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  1. 50601
  2. 50602

    A novel missense pathogenic variant c.9455T > G (p.L3152R) in CDH23 underlies autosomal recessive non-syndromic hearing loss by Ladan Sadeghian, Marziyeh Hoseinzadeh, Mohammad reza Pourreza, Saeed Khalili, Najmeh Fattahi, Mohammad Amin Tabatabaiefar

    Published 2025-06-01
    “…This study aimed to identify the genetic cause of autosomal recessive non-syndromic hearing loss (ARNSHL) in a large Iranian family using next-generation sequencing and structural bioinformatics. Methods After a comprehensive clinical evaluation of a large family with a history of HL the GJB2 gene was sequenced, and 7 loci were screened through genetic linkage analysis. …”
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    Article
  3. 50603

    The smart senior care demand in China in the context of active ageing: a qualitative study with multiple perspectives by Qiyuan Huang, Fang Liu, Song Ge, Shuang Teng, Xiang Wu, Xiao Zhang, Zhe Qu, Ying Li, Aming Wang, Mei Li, Xianping Tang, Xianping Tang

    Published 2025-04-01
    “…This study aimed to explore the needs and expectations of relevant stakeholders of smart senior care in China in the context of active aging.MethodsThis is a qualitative descriptive study, in which 21 semi-structured interviews were conducted between October 2021 and March 2022. …”
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  4. 50604

    Towards a net-zero healthcare system in Kenya: Stakeholder perspectives on opportunities, challenges and priorities by Iris Martine Blom, Melvine Anyango Otieno, Susannah Mayhew, Neil Spicer, Andy Haines, Sarah Whitmee

    Published 2025-03-01
    “…Methods: This study employs qualitative methods, including 21 semi-structured interviews with key stakeholders and a Delphi consensus process, to explore stakeholder perspectives on Kenya's journey to a net-zero healthcare system. …”
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    Article
  5. 50605
  6. 50606

    Aligning the principles and practice of research integrity and research fairness in global health: a mixed-methods study by Sandra Alba, Rutuja Patil, Martijn Wienia, Masja Straetemans, Francis Kombe, Gowri Gopalakrishna, Harry Coleman, Nima Yaghmaei, Joseph Bukulu Sempa, Jake D Mathewson, Hannah Kabelka, Preeti Sohoni

    Published 2024-03-01
    “…Despite extensive academic discussions, empirical data on these aspects, especially in the context of global health, remain limited.Methods To address this gap, we conducted a mixed-methods study focusing on research integrity and fairness. …”
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    Article
  7. 50607

    Culinary connections: The mediating role of customer brand co-creation behavior in gastronomic and revisit intentions by Ni Made Purnami, Ni Wayan Mujiati, Ayu Putu Laksmi Danyathi, Uswatun Siwi Kartika Sari, Desak Komang Dea Marcellina Putri Darmada

    Published 2025-01-01
    “…This study investigates the mediating role of customer brand co-creation behavior in the effect of gastronomic experience on revisit intention among Generation Z café visitors in Bali, Indonesia. Data were collected from 250 respondents via an online survey and analyzed using Partial Least Squares Structural Equation Modeling. …”
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  8. 50608
  9. 50609

    Technology Anxiety in Virtual Reality Adoption: Examining the Impact of Age, Past Experience, and Cybersickness by Eman Al Khalifah, Ramy Hammady, Mahmoud Abdelrahman, Ons Al-Shamaileh, Mostafa Marghany, Hatana El-Jarn, Alyaa Darwish, Yusuf Kurt

    Published 2025-01-01
    “…Using an extended Technology Acceptance Model (TAM), the research integrates age and past use as antecedents of TA and evaluates their influence on perceived ease of use (PEoU), perceived enjoyment (PENJ), and user attitudes. Data from 206 participants were analysed using Partial Least Squares Structural Equation Modelling (PLS-SEM) following a VR pilgrimage experience. …”
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    Article
  10. 50610

    Exploring the Relationship Between Excessive Social Media Use and Eating Disorders Among Young Adults: Evidence From a Bangladesh‐Based Cross‐Sectional Study by Trisha Mallick, Md. Hasan Al Banna, Tasnim Rahman Disu, Shammy Akter, Tareq Mahmud, Tasnima Akhter Tasin, Nargees Akter, Md. Saiful Alam, Md. Nazmul Hassan

    Published 2025-05-01
    “…Methods We conducted an online‐based cross‐sectional study among 550 young adults aged 18 to 27 in Bangladesh. A structured questionnaire was used to obtain the survey data. …”
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    Article
  11. 50611
  12. 50612

    Wind speed forecasting approach using conformal prediction and feature importance selection by Cesar Vinicius Zuege, Stefano Frizzo Stefenon, Cristina Keiko Yamaguchi, Viviana Cocco Mariani, Gabriel Villarrubia Gonzalez, Leandro dos Santos Coelho

    Published 2025-07-01
    “…Furthermore, a Bayesian Optimization with Tree-structured Parzen Estimators (BO-TPE) will be used to tune the hyperparameters of the models. …”
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  13. 50613

    Peer support and online cognitive behavioural therapy for substance use concerns: protocol for a randomised controlled trial by Allison Crawford, Claire de Oliveira, Glyn Davies, Lena C Quilty, Gord Garner, Elizaveta Klekovkina, Jeffrey D Wardell, Sarah Elison-Davies, Michael Corman, Jeffrey Alfonsi, John Weekes

    Published 2022-12-01
    “…Results will help to optimise the effectiveness of structured online substance use interventions provided as an adjunct to standard care in hospital-based treatment programmes. …”
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    Article
  14. 50614

    Integrative analysis of saliva-derived exosomal proteome and lipidome for the diagnosis of esophageal squamous cell carcinoma by Wei Zhong, Jian Liu, Junhua Xie, Zhiyan Zhang, Zhiwen Gong, Zhixiang Yan, Qingdong Cao

    Published 2025-08-01
    “…The proteomic characteristics of ESCC were primarily manifested in immune responses, disruption of tissue structural homeostasis, and enhanced antifungal and antimicrobial humoral immune responses. …”
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    Article
  15. 50615

    An Overview of Treatment in Pediatric Bladder-bowel Dysfunction: A Single-Center Experience by Mahli Batuhan Özdoğar, Ömer Ergin, Hasan Turan, Özgür Özdemir Şimşek, Özgür Olukman

    Published 2025-08-01
    “…Objective: This study aimed to evaluate the clinical characteristics, treatment responses, and outcomes of pediatric patients diagnosed with bladder-bowel dysfunction, highlighting a structured management approach including urotherapy, pharmacotherapy, and rehabilitation techniques. …”
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    Article
  16. 50616

    Optimized enrichment of murine blood–brain barrier vessels with a critical focus on network hierarchy in post-collection analysis by Hanaa Abdelazim, Audra Barnes, James Stupin, Ranah Hasson, Carmen Muñoz-Ballester, Kenneth L. Young, Stefanie Robel, James W. Smyth, Samy Lamouille, John C. Chappell

    Published 2025-05-01
    “…Positioned between upstream arteries and downstream veins, these microvessels have unique structural features, such as the absence of vascular smooth muscle cells (vSMCs) and a relatively thin basement membrane, to facilitate highly efficient yet selective exchange between the circulation and the brain interstitium. …”
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  17. 50617

    Lessons learned from the COVID-19 pandemic: opportunities and challenges to leverage investments in HIV, tuberculosis and malaria for pandemic preparedness and response by Abu Abdul-Quader, Jinkou Zhao, Laurence Slutsker, Kevin M De Cock, Anthony Mounts, Deanna Tollefson, Naisa Rahman, Meng-Yu Chen, Yannick Kamga, Samuel Ngobua, David Lowrance, Joseph S Bresee, Arunmozhi Balajee

    Published 2025-04-01
    “…This manuscript systematically documents how these programmes were used in response to understand both the barriers and facilitators encountered in the process.Methods From March through August 2023, we conducted 72 structured interviews with staff in 13 countries who played central roles in the response. …”
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    Article
  18. 50618

    Addressing System Challenges in Mental Health Services Research for Youth in the Child Welfare System: Insights From the Foster Care Family Navigator Trial by Marina Tolou‐Shams, Megan Ramaiya, Jannet L. Salas, Adrian Aguilera, Martha Shumway, Brian Borsari, Emily Dauria, Jill D. Berrick

    Published 2025-03-01
    “…Systems‐level challenges that impacted proposed research trial design and data collection included: (1) Limited system staff time and compensation processes; (2) Staff training and knowledge; and (3) System disruptions. …”
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  19. 50619

    A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune Evasion by Roshan Nepal, Ghais Houtak, George Bouras, Sholeh Feizi, Gohar Shaghayegh, Keith Shearwin, Mahnaz Ramezanpour, Alkis James Psaltis, Peter‐John Wormald, Sarah Vreugde

    Published 2025-08-01
    “…Further, φSa3int prophage domestication led to reduced phagocytosis implying φSa3int prophage mediates escape of S. aureus from human innate immunity. Our data further show that in addition to adding novel prophage‐encoded virulence, φSa3int prophage domestication also affects the expression of non‐prophage (bacterial) genes and suppresses expression of structural proteins of resident prophages. …”
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  20. 50620