Hints of Disk Substructure in the First Brown Dwarf with a Dynamical Mass Constraint by Alejandro Santamaría-Miranda, Pietro Curone, Laura Pérez, Nicolas T. Kurtovic, Carolina Agurto-Gangas, Anibal Sierra, Itziar de Gregorio-Monsalvo, Nuria Huélamo, James M. Miley, Aina Palau, Paola Pinilla, Isabel Rebollido, Álvaro Ribas, Pablo Rivière-Marichalar, Matthias R. Schreiber, Jinshi Sai, Benjamín Carrera

“…This tentative disk structure could be linked to a possible planetary companion in the process of formation. …”
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Multi-omics analysis in primary T cells elucidates mechanisms behind disease-associated genetic loci by Chenfu Shi, Danyun Zhao, Jake Butler, Antonios Frantzeskos, Stefano Rossi, James Ding, Carlo Ferrazzano, Charlotte Wynn, Ryan Malcolm Hum, Ellie Richards, Muskan Gupta, Khadijah Patel, Chuan Fu Yap, Darren Plant, Richard Grencis, Paul Martin, Antony Adamson, Stephen Eyre, John Bowes, Anne Barton, Pauline Ho, Magnus Rattray, Gisela Orozco

“…We generated 108 Hi-C libraries (49 billion reads), 128 RNA-seq libraries and 126 ATAC-seq libraries. These data enhance our understanding of the mechanisms by which GWAS variants impact gene regulation, revealing how genetic variation alters chromatin accessibility and structure in primary cells at an unprecedented scale. …”
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Polarization Characteristics of the Hyperactive FRB 20240114A by Jin-Tao Xie, Yi Feng, Di Li, Yong-Kun Zhang, Deng-Ke Zhou, Yuanhong Qu, Xiang-han Cui, Jian-Hua Fang, Jia-Ying Xu, Chen-Chen Miao, Mao Yuan, Chao-Wei Tsai, Pei Wang, Chen-Hui Niu, Xianglei Chen, Mengyao Xue, Junshuo Zhang

“…We analyze the fluence and waiting-time distributions of FRB 20240114A, revealing a right-skewed fluence distribution and a bimodal waiting-time structure, suggesting intrinsic emission timescales and potential multiple burst populations. …”
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Non-typhoidal Salmonella among slaughterhouse workers and in the pork value chain in selected districts of Uganda by Velma Kivali, Velma Kivali, Velma Kivali, Kristina Roesel, Kristina Roesel, Ian Dohoo, Lordrick Alinaitwe, Lordrick Alinaitwe, Lordrick Alinaitwe, Lordrick Alinaitwe, James Katamba Bugeza, James Katamba Bugeza, Jolly Justine Hoona, Denis Rwabiita Mugizi, Denis Rwabiita Mugizi, Clovice Kankya, Sinh Dang-Xuan, Sinh Dang-Xuan, Istvan Szabo, Uwe Rösler, Anika Friese, Elizabeth A. J. Cook, Elizabeth A. J. Cook

“…Antimicrobial resistance profiles were determined using tube microdilution and Sensititre® EUVSEC3® plates. Semi- structured questionnaires with 35 questions were used to collect data on demographics, work related risk factors and activities outside the slaughterhouse.Results and discussionOverall NTS prevalence was 19.2% (365/1899). …”
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Effectiveness of a multicomponent intervention to promote physical activity during the school day: rationale and methods of the MOVESCHOOL study by Francisco J. Bandera-Campos, Francisco J. Bandera-Campos, Alberto Grao-Cruces, Alberto Grao-Cruces, Daniel Camiletti-Moirón, Daniel Camiletti-Moirón, Fátima Martín-Acosta, Fátima Martín-Acosta, Raúl Muñoz-González, María González-Pérez, María González-Pérez, Abel Ruiz-Hermosa, Abel Ruiz-Hermosa, Miguel Vaquero-Solís, Miguel Vaquero-Solís, Carmen Padilla-Moledo, Carmen Padilla-Moledo, David Sánchez-Oliva, David Sánchez-Oliva, David Sánchez-Oliva

“…Additionally, qualitative data were gathered through semi-structured individual interviews and focus groups, and information will be evaluated with thematic analysis.DiscussionThe MOVESCHOOL study represents a pioneering effort in Spain, being the first of its kind to evaluate the effectiveness of a multicomponent programme in secondary schools. …”
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Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanoma by Andrea Anichini, Francesca P. Caruso, Vincenzo Lagano, Teresa M. R. Noviello, Rossella Tufano, Gabriella Nicolini, Alessandra Molla, Ilaria Bersani, Francesco Sgambelluri, Alessia Covre, Maria F. Lofiego, Sandra Coral, Anna Maria Di Giacomo, Elena Simonetti, Barbara Valeri, Mara Cossa, Filippo Ugolini, Sara Simi, Daniela Massi, Massimo Milione, Andrea Maurichi, Roberto Patuzzo, Mario Santinami, Michele Maio, Michele Ceccarelli, Roberta Mortarini, On behalf of the EPigenetic Immune-oncology Consortium Airc (EPICA) investigators

“…Abstract Background We developed an integrated multi-omics analysis in metastatic melanoma (MM) cohorts to associate DNA methylation profiles with tumor progression, survival, response to adjuvant immunotherapy, structure of the tumor immune microenvironment and transcriptional programs of immunity and melanoma differentiation. …”
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Prevalence of hepatitis C virus co-infection in adults living with HIV in Mexico: a cross-sectional, seroprevalence study in a nationally representative sampleResearch in context by Pablo F. Belaunzarán-Zamudio, Juan L. Mosqueda-Gómez, J. Oggún Cano-Torres, Claudia Guillén-López, Teresa Muñoz-Trejo, Kenia Escobedo-López, Alejandro Rivera-Marroquín, Akio Murakami-Ogasawara, José L. Sánchez-Bello, Margarita M. Rosas-Dossetti, Elizabeth Papaqui-Limón, Alethse De la Torre-Rosas, Juana Díaz-García, Juan G. Sierra-Madero, Pablo F. Belaunzarán-Zamudio, Juan L. Mosqueda-Gómez, J. Oggun Cano-Torres, Claudia Guillén-López, Teresa Muñoz-Trejo, Kenia Escobedo-López, Alejandro Rivera Marroquin, Akio Murakami-Ogasawara, José L. Sánchez-Bello, Margarita M. Rosas-Dossetti, Elizabeth Papaqui-Limón, Alethse De la Torre-Rosas, Juana Díaz-García, Bibiana M. Barbosa-Ramírez, Oscar Castillo-Soria, Alain Espinoza-Pérez, Jorge Gaxiola-Lugo, Alfredo Pérez-Valenzuela, Krissel García-Hernández, Elvira E. Riojas-Moncada, Juana Díaz-García, Juan Beltrán-Saldaña, Felipe De Jesús Escobar-Del Real, Ma. del Pilar Abarca-de Hoyos, Susana Raviela, Ma. Eugenia Figueroa-Santana, Jorge A. Gamboa-Marroquin, Andrea Cárdenas-Ortega, Mario J. Hernández-Morales, Adonay Jiménez-Jiménez, Manuel Vidal-López, Roberto Rodríguez-Díaz, Berenice Robles-Villafuerte, Arturo Alatorre-Manjarrez, Corazón Moreno-Mex, Ivonne Sánchez-López, Jorge Silva-Herrera, Nora Mora-Suárez, Daniel Pérez-Larios, Juan G. Sierra-Madero

“…Methods: Using a complex-survey design, we collected blood samples and applied structured questionnaires between May 2nd, 2019 and February 17th, 2020 in a nationally, representative sample of adults receiving care for HIV-infection in 24 randomly selected HIV-care centres in 8 socio-demographically regions in Mexico. …”
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Unearthing the climate history of the Atacama Desert in northern Chile – deep drilling in two clay pans of the Coastal Cordillera by V. Wennrich, J. Diederich-Leicher, B. N. Blanco-Arrué, B. N. Blanco-Arrué, C. Büttner, S. Buske, E. Campos Sepulveda, T. Dunai, J. Feller, E. Galego, A. Hasberg, N. Leicher, D. A. López, J. Maldonado, A. Medialdea, A. Medialdea, L. Ninnemann, L. Ninnemann, R. Perryman, J. C. Ríos-Contesse, B. Ritter, S. Scheidt, B. Vargas-Machuca, P. Yogeshwar, P. Yogeshwar, M. Melles

“…Electromagnetic and seismic surveys yielded a three-layer structure in both basins consisting of the resistive basement overlain by a low-resistivity basal and a high-resistivity upper sediment unit with total sediment thicknesses of more than <span class="inline-formula">∼</span> 100 and <span class="inline-formula">∼</span> 160 m in the Playa Adamito Grande (PAG) and Paranal clay pans, respectively. …”
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Kun–Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile by Yan Ma, Xingdong Chen, Jie Wei, Li Guo, Jian Huang, Li Xie, Lei Chen, Ping Lu, Wei Sun, Wei Shi, Feng Ding, Liping Zhang, Yue Zhang, Linlin Zhang, Rui Song, Yi Huang, Jun Shen, Hong Xu, Zhigang Chen, Qian Shen, Ying Ma, Yiwen Zhang, Hongxia Li, Yihui Zhai, Biao Xu, Xian Zhou, Jun Sun, Bing Wu, Rui Su, Xiaoyan Yu, Jianhong Zhu, Yihong Huang, Ling Gong, Nana Wu, Jingjing Sun, Tianyi Liu, He Yuan, Yiwen Shen, Jiaojiao Liu, Xia Han, Juanjuan Wu, Yinghua Sun, Suxiang Xu, Qinyi Zhang, Na Xie, Jianfeng Ji, Weizhi Mo, Yuanxin Liu, Xinghua Shi, Wanshan Qiu, Jiapeng Mi, Juhua Yan, Minghui Zhu, Pei Feng, Wenqian Sheng, Mingqin Tai, Chunqin Zhou, Qian Jin, Chengyu Gu, Xiujuan Huang, Qinfang Qian, Yixin Cao, Haochen Shen, Ziwen Xue, Yucui Ma, Juan Tian, Yingdan Zhang, Weiyuan Zhuang, Kaiqun Yang, Xiaohui Shen, Yanwei Gu, Beibei Shi, Chenhong Pan, Hongmei Zhou, Xiuchen Zhang, Meihua Tang, Kaixuan Gu, Hongping Liu, Yuanxian Li

“…Structured CKD questionnaires were administered, and biosamples (urine and dried blood spots) were obtained for the long-term storage and analysis using standard procedures. …”
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The effect of age and sex on brain metabolites: from childhood to adulthood by María Ortuño, Adriana Fortea, Isabel Valli, Emma Muñoz-Moreno, Roger Borràs, Irene Martínez-Serrano, Mireia Masias Bruns, Patricia Camprodon-Boadas, Enric Vilajosana, Lydia Fortea, Joaquim Raduà, Elena de la Serna, Inmaculada Baeza, Josefina Castro-Fornieles, Gisela Sugranyes

“…This cross-sectional study set out to examine the relationship between levels of neurometabolites and age and sex —key modulators of brain function and structure—, continuously from childhood to early adulthood, in areas relevant to the study of psychiatric disorders.Magnetic resonance spectroscopy (¹H MRS) data was acquired in the dorsomedial prefrontal region (dmPF) and the medial temporal lobe (mTL) in 128 healthy individuals aged 7 to 34 years, 68.5 % females (ndmPF = 124; nmTL = 75). …”
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Incidence, clinical and genomic trends of hospital- and Non-hospital-onset KPC-producing Klebsiella pneumoniae infections before and during the COVID-19 era: a ten-year interrupted... by Manuel Recio-Rufián, Teresa López-Viñau, Víctor Gálvez-Soto, Ángela Cano, Rafael Ruiz-Montero, Belén Gutiérrez-Gutiérrez, Irene Gracia-Ahufinger, Germán Peñalva, Juan Antonio Marín-Sanz, Miriam Marín-Sanz, David Segorbe, Juan Jesús Pineda-Capitán, Montserrat Muñoz-Rosa, Cristina Riazzo, Federico Giovagnorio, Elisa Ruiz-Arabi, José David Torres-Peña, Juan José Castón, Isabel Machuca, Inmaculada Salcedo-Leal, Luis Martínez-Martínez, Elena Pérez-Nadales, Julián Torre-Cisneros, KLEBMAN study group

“…Whole-genome sequencing and PERMANOVA evaluated the genomic structure of ST512/KPC-3 isolates. Multivariable regression analysed the association between infection type and clinical outcomes. …”
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Safety of a co-designed cognitive behavioural therapy intervention for people with type 1 diabetes and eating disorders (STEADY): a feasibility randomised controlled trialResearch... by Marietta Stadler, Natalie Zaremba, Amy Harrison, Jennie Brown, Divina Pillay, Jacqueline Allan, Rachael Tan, Salma Ayis, Emmanouela Konstantara, Janet Treasure, David Hopkins, Khalida Ismail

“…Baseline mental health data (Structured Clinical Interview for DSM-5, SCID-5RV), and secondary biomedical outcomes (HbA1c; glucose time in range; TIR) and person-reported outcome measures (PROM: Diabetes Eating Problems Survey-Revised, DEPS-R; Eating Disorder Examination Questionnaire Short, EDE-QS; Type 1 Diabetes Distress Scale, T1DDS; Generalised Anxiety Disorder Assessment, GAD-7; Patient Health Questionnaire, PHQ-9; Impact of Diabetes Profile, DIDP) were collected. …”
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Hemoglobin state-flux: A finite-state model representation of the hemoglobin signal for evaluation of the resting state and the influence of disease. by Randall L Barbour, Harry L Graber, San-Lian S Barbour

“…Inspection of the coefficient arrays reveals that they are governed predominantly by first-order rate processes, and that each array class exhibits preferred structure that is mainly independent of the others. …”
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Gonadal Histology and Expression Analysis of Sex Characteristic Genes in Grass Carp at Different Ages by Bo QI, Shengjie LI, Jinxing DU, Xiaofang XIAO, Dongyun ZHANG, Tao ZHU, Caixia LEI, Zhijun LIU, Hongmei SONG

“…Anti-Müllerian hormone (amh) regulates the structure of reproductive organs and the differentiation and development of reproductive cells. …”
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Effects of nutritional counseling on dietary patterns in patients with mild cognitive impairment: insights from the BrainFit-Nutrition study by Etienne Hanslian, Etienne Hanslian, Melanie Dell’Oro, Julia K. Schiele, Julia K. Schiele, Farid I. Kandil, Farid I. Kandil, Dzenita Hasanbasic, Dzenita Hasanbasic, Cirus Henn, Elmar Graessel, Julia-Sophia Scheuermann, Petra Scheerbaum, Andreas Michalsen, Andreas Michalsen, Michael Jeitler, Michael Jeitler, Michael Jeitler, Michael Jeitler, Christian S. Kessler, Christian S. Kessler, Christian S. Kessler

“…While the primary outcome of the BrainFit-Nutrition study assessed the impacts of diet and cognitive training on cognitive performance, this secondary data analysis focuses on dietary habits and their changes over time. …”
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Probiotics improve eggshell quality via regulating microbial composition in the uterine and cecum by Yuxiang Lu, Hengyong Xu, Zhi Hu, Dan Li, Alma Rustempasic, Yuxin Zhou, Qingqing Deng, Jiaxue Pu, Xiaoling Zhao, Yao Zhang, Yiping Liu, Yan Wang

“…Furthermore, the changes of these phenotypes are closely related to the microbial structure of the uterus and cecum. Overall, the data suggest that dietary probiotics improved uterine and cecal microbiota, optimized egg quality, eggshell quality, uterus development, and regulated mineralization gene expression and ion content in serum and eggshell, thereby improving productivity of laying hens. …”
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Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations by Adrien Goncalves, Susana Ochoa, Steffen Moritz, Łukasz Gawęda, Alvaro Cavieres, Caroline König, Rabea Fischer, Antonia Meinhart, Maria Lamarca, Rosa Ayesa-Arriola, Ryan Balzan, Kerem Böge, Tania Lecomte, Stéphane Raffard, Fabrice Berna

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Directly replanting with GF296 extends the years of ratooning and yield in sugarcane by Huiwen Zhou, Hanmin Luo, Youchen Wei, Hongchui Wei, Yuanke Wei, Ming Liu, Ming Li, Jianhua You, Yangrui Li, Haifeng Yan, Lihang Qiu

“…At harvest in the 3rd, 4th, and 5th ratoon years, data on important agronomic traits and sucrose content of the sugarcane populations under the replanting and non-replanting treatments were investigated. …”
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Water Supply Reliability in Maweizao Irrigation Area Based on GIS by FU Jian-jun, LI Yun-qi, YUAN Li, CHEN Peng, GONG Rou-yan

“…[Methods] Using daily meteorological data from 1989 to 2019 in the irrigation area, the intra-seasonal rainfall frequency analysis method was employed to identify typical representative years and characteristic values for normal years (P=50%), moderately dry years (P=75%), and dry years (P=90%). …”
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The difficult process of autonomous choice: using I-poems to understand experiences of abortion-seekers in The Netherlands by Lianne Holten, Rosalie van der Wolf, Marit S. G. van der Pijl

“…This qualitative feminist study used transcripts of semi-structured, in-depth interviews with abortion-seekers from previous research to create I-poems. …”
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