Gender-affirming hormonal therapy induces a gender-concordant fecal metagenome transition in transgender individuals by Timur Liwinski, Matthias K. Auer, Johanna Schröder, Ina Pieknik, Christian Casar, Dorothee Schwinge, Lara Henze, Günter K. Stalla, Undine E. Lang, Alina von Klitzing, Peer Briken, Thomas Hildebrandt, Jeanne C. Desbuleux, Sarah V. Biedermann, Paul-Martin Holterhus, Corinna Bang, Christoph Schramm, Johannes Fuss

“…Abstract Background Limited data exists regarding gender-specific microbial alterations during gender-affirming hormonal therapy (GAHT) in transgender individuals. …”
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Edible microcapsules containing canola oil for cultivated meat production by Juliano Douglas Silva Albergaria, Ana Elisa Antunes dos Santos, Jorge Luís Melo Guadalupe, Isabella Paula de Araújo, Aline Gonçalves Lio Copola, João Paulo Ferreira Santos, Erika Cristina Jorge, Luciana de Oliveira Andrade, Aline Bruna da Silva

“…Fourier Transform Infrared Spectroscopy (FTIR) further validated the chemical structure of the materials. Microsphere stability in aqueous media was also evaluated. …”
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Transfer Learning Empowered Multiple‐Indicator Optimization Design for Terahertz Quasi‐Bound State in the Continuum Biosensors by Shengfeng Wang, Bingwei Liu, Xu Wu, Zuanming Jin, Yiming Zhu, Linjie Zhang, Yan Peng

“…However, prior approaches primarily establish one‐to‐one mappings between structure and optical response, neglecting the trade‐offs among key performance indicators. …”
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The genome landscape of the Xinglong buffalo by Yuan Chai, Shiyuan Li, Hui Wu, Yong Meng, Yujing Fu, Hong Li, Guansheng Wu, Junming Jiang, Taoyu Chen, Yuqing Jiao, Qiaoling Chen, Li Du, Lianbin Li, Churiga Man, Si Chen, Hongyan Gao, Wenguang Zhang, Fengyang Wang

“…The population genetic structure analysis indicates that at K = 3, the Xinglong buffalo for the first time showed a distinct ancestral origin from other water buffalo. …”
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“You do it for the patient”: a qualitative analysis of changes to primary care nurses’ workplace demands and resources during the COVID-19 pandemic in Canada by Sarah Spencer, Lindsay Hedden, Julia Lukewich, Emily Gard Marshall, Maria Mathews, Samina Idrees, Jennifer E. Isenor, Ruth Martin-Misener, Leslie Meredith, Crystal Vaughan, Dana Ryan, Dana Ryan

“…Accordingly, we sought to understand the personal and professional experiences of nurses working in primary care settings in Canada during the COVID-19 pandemic to inform future pandemic responses and health workforce planning that account for primary care nurses’ mental and physical needs.MethodsWe conducted semi-structured interviews with licensed and registered practical nurses, registered nurses, and nurse practitioners working in primary care in four Canadian provinces: British Columbia, Newfoundland and Labrador, Nova Scotia, and Ontario. …”
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The clinical spectrum associated with ERCC5 mutations: Is there a relationship between phenotype and genotype? by Jinpeng Zhang, Jiannan Ma, Yuanyuan Luo, Siqi Hong, Li Jiang, Tianyi Li

“…The gene mutation has not been reported and was predicted to seriously affect the protein structure. According to a review of 59 cases of ERCC5 mutations, cerebrooculofacioskeletal syndrome (COFS) occurred in 16 cases, XP in 19 cases, and XP/CS in 24 cases. …”
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Design of cross-reactive antigens with machine learning and high-throughput experimental evaluation by Chelsy Chesterman, Thomas Desautels, Luz-Jeannette Sierra, Kathryn T. Arrildt, Adam Zemla, Edmond Y. Lau, Shivshankar Sundaram, Jason Laliberte, Lynn Chen, Aaron Ruby, Mark Mednikov, Sylvie Bertholet, Dong Yu, Kate Luisi, Enrico Malito, Corey P. Mallett, Matthew J. Bottomley, Robert A. van den Berg, Daniel Faissol

“…The top mutant identified underwent biophysical and x-ray crystallographic characterization to confirm that the overall structure of fHbp was maintained throughout this epitope engineering experiment. …”
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Myths and misconceptions of intimate partner violence among sexual and gender minorities: a qualitative exploration by Stefan Kurbatfinski, Stefan Kurbatfinski, Nicole Letourneau, Nicole Letourneau, Nicole Letourneau, Nicole Letourneau, Nicole Letourneau, Susanne Marshall, Dawn McBride, Jason Novick, Keira Griggs, Arielle Perrotta, Arielle Perrotta, Morgan Daye, Carrie McManus, Kendra Nixon

“…This study sought to: (1) develop a compendium of myths and misconceptions that SGM individuals exposed to IPV and relevant service providers shared they encountered; (2) describe the impacts of these myths and misconceptions on SGM individuals experiencing IPV; and (3) make recommendations to address these myths and misconceptions.MethodsThis qualitative study used data from a larger project focused on SGM IPV where SGM individuals who experienced IPV (n = 18) and service providers who supported SGM individuals experiencing IPV (n = 8) were interviewed using semi-structured formats. …”
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Evaluating the new family medicine internship programmes in the Western Cape, South Africa by Lauren N. Hutton, Louis S. Jenkins, Robert Mash, Klaus von Pressentin, Steve Reid, Jennie Morgan, Paul Kapp

“…Many interns reported no structured teaching programme (41.7% – 55.6%). Most supervision was from medical officers and registrars. …”
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Recognition and cleavage of human tRNA methyltransferase TRMT1 by the SARS-CoV-2 main protease by Angel D'Oliviera, Xuhang Dai, Saba Mottaghinia, Sophie Olson, Evan P Geissler, Lucie Etienne, Yingkai Zhang, Jeffrey S Mugridge

“…We also determined the structure of an Mpro-TRMT1 peptide complex that shows how TRMT1 engages the Mpro active site in an uncommon substrate binding conformation. …”
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Bayesian trial of adalimumab versus secukinumab for children with juvenile idiopathic arthritis associated uveitis or chronic anterior uveitis by Athimalaipet V Ramanan, Andrew D Dick, Thomas Jaki, Gianmarco Caruso, David S Robertson, Ashley P Jones, Ben Hardwick, Sian Drake, Balini Balasubramaniam, Coziana Ciurtin, Ivan Foeldvari, Elke O Kreps, Alice Leahy, Kristina May, Pierre Quartier, Matthieu P Robert, Gabriele Simonini, Catherine Guly, Michael W Beresford

“…Methods Nine international experts in paediatric rheumatology, paediatric ophthalmology and/or paediatric uveitis took part in a structured Bayesian prior elicitation meeting. Results The final consensus was that adalimumab is expected to yield a higher response rate than secukinumab (mean 0.67 vs. 0.55). …”
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Knowledge, attitudes, practices, and vaccination coverage of medical students toward hepatitis B virus in North Sudan, 2023 by Osama M.I. Mohamed, Hassan S.H. Mohammedali, Shimaa N.A. Mohamed, Hussein A.S. Ahmed, Alaa A.M. Mohamedsalih, Ola M.A. Abdalgani, Tebian A.A. Mohammedosman, Alaa A.A. Ali, Thuiba A.H. Ali, Othman N.O. Amin, Mohamed A. Issak, Mohamed O. Abdelaziz

“…Methods A cross-sectional study was conducted from January to June 2023 among medical students in North Sudan. Data were collected using a structured scale using online Google Forms. …”
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Assessment of knowledge, attitude, anxiety level and perceived mental healthcare needs toward mpox infection among nursing students: A multi-center cross-sectional study by Mona Gamal Mohamed, Md Rabiul Islam, Sirwan Khalid Ahmed, Shimaa Abdelrahim Khalaf, Hanan Abdelrazik Abdelall, Kochr Ali Mahmood, Ekram M. Abdel Khalek, Judie Arulappan, Syed Masudur Rahman Dewan

“…Participants completed a structured questionnaire covering sociodemographic information, knowledge of mpox, attitudes towards the disease, levels of anxiety, and perceived mental healthcare needs. …”
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Association of non-exercise physical activity with sarcopenia compared with that of exercise habits among community-dwelling older adults: A 7-year follow-up from the Kashiwa Cohor... by Weida Lyu, Tomoki Tanaka, Bo-Kyung Son, Yasuyo Yoshizawa, Katsuya Iijima

“…Therefore, NEPA may be a practical alternative to structured exercises for older adults.…”
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Study on the incremental carbon sink of tea plantations under spatio-temporal variation characteristics by Yaxiang Pan, Yaxiang Pan, Jingling Bao, Jingling Bao, Yuxuan Ji, Yuxuan Ji, Wen Li, Wen Li, Weiyu Lin, Shuisheng Fan, Shuisheng Fan, Shuisheng Fan, Liyu Mao, Liyu Mao

“…In this study, we selected the data of nine prefecture-level cities in Fujian Province, a major province of tea industry, from 2010 to 2022, and borrowed the standard deviation ellipse and trend surface analysis methods to clarify the spatial and temporal evolution of the carbon sinks in tea plantations, and combined with the geodetic detector model to explore the driving factors of spatial differentiation. …”
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Atmospheric Boundary Layer Stability in Urban Beijing: Insights from Meteorological Tower and Doppler Wind Lidar by Linlin Wang, Bingcheng Wan, Yuanjian Yang, Sihui Fan, Yi Jing, Xueling Cheng, Zhiqiu Gao, Shiguang Miao, Han Zou

“…The limited understanding of the structure of the urban surface atmospheric boundary layer can be attributed to its inherent complexity, as well as a deficiency in comprehensive measurements. …”
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Changes in the intestinal microbiota induced by the postnatal environment and their association with hypertension by Patrizia Dardi, Camille Perella Coutinho, Sarah de Oliveira, Simone Aparecida Teixeira, Renaide Rodrigues Ferreira Gacek, Eduardo Purgatto, Marco Aurélio Ramirez Vinolo, Marcelo Nicolás Muscará, Luciana Venturini Rossoni

“…In this sense, the current study explored the influence of normotensive and hypertensive postnatal environments on the intestinal microbiota structure, composition, and functional capacity of SHR and Wistar rats. …”
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Development of Ecological Environment Monitoring Network System in China by Qiao Wang, Shaomin Liu, Guoqiang Wang, Yinglan A, Baolin Xue, Ziwei Xu, Jin Wu

“…Although China has built a large-scale, comprehensive, and well-structured ecological environment monitoring network, it is insufficient to meet the major national demands of the new era, such as reducing pollution and carbon emissions, ecological protection and restoration, and addressing climate change. …”
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Prevalence and intensity of intestinal and soil-transmitted helminths infection among children in internally displaced camps in Mogadishu Somalia by Bashiru Garba, Hodo Aideed Asowe, Najib Isse Dirie, Yushau Umar, Abdikani Omar Salah, Ahmed Abdirahim Hussien, Ikram Abdirahman Mohamud Alasow, Fartun Abdullahi Hassan Orey, Jihaan Hassan, Jamal Hassan Mohamoud, Mohamed Hussein Adam, Mohamed Adam Mahamud, Mohamed Mustaf Ahmed

“…This study was undertaken to assess the prevalence and intensity of intestinal and soil-transmitted helminth infections among school-aged children in the Deyniile and Kahda internally displaced persons camps. A well-structured questionnaire was used to collect sociodemographic, behavioral and environmental data from the respondents, while fresh stool samples were collected to detect helminths via the cellophane-based Kato–Katz technique. …”
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Clinical and epidemiological characteristics of imported intestinal infections in children by E. Yu. Pylaeva, N. N. Zverevа, А. А. Erovichenkov, S. K. Pylaeva, E. A. Artamonova, N. Yu. Pshenichnaya, A. M. Demkina, O. N. Solodovnikova, Yu. N. Khlypovka, A. Yu. Dyagileva, A. Kh. Nurpeysova, A. U. Berestovskaia, O. V. Shamsheva, D. N. Protsenko

“…Imported intestinal infections most often occurred with symptoms of gastroenteritis, were assessed by CDS at 5 points, and rotavirus predominated in the etiological structure.…”
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