Therapeutic potential of miR-204-5p in intervertebral disc degeneration: targeting the SSRP1/NF-κB pathway to inhibit apoptosis by Chenhao Zhao, Qiuwei Li, Cailiang Shen

“…This study investigated the protective role of miR-204-5p in IVDD by targeting the Structure-specific recognition protein-1(SSRP1)/nuclear factor-kappa B (NF-κB) signaling pathway. …”
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Employing Quantum Entanglement for Real-Time Coordination of Distributed Electric Vehicle Charging Stations: Advancing Grid Efficiency and Stability by Dawei Wang, Hanqi Dai, Yuan Jin, Zhuoqun Li, Shanna Luo, Xuebin Li

“…Visual analytics using 3D surface plots and disaggregated bar charts confirm structured demand-price interactions and smooth, stable price evolution. …”
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Plant-derived antiviral drugs as novel hepatitis B virus inhibitors: Cell culture and molecular docking study by Mohammad K. Parvez, Md. Tabish Rehman, Perwez Alam, Mohammed S. Al-Dosari, Saleh I. Alqasoumi, Mohammed F. Alajmi

“…Being the most important drug target, a 3-D structure of HBV polymerase (Pol/RT) was modeled and docked with the active compounds, including lamivudine as standard. …”
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Neisseria Meningitidis Carriage Among Hajj and Umrah Pilgrims: A Systematic Review and Meta-Analysis by Raghad Alhajaji, Manal Alfahmi, Sadin Ayman Alamri, Aseel Ayman Alamri, Khalid Al Sulaiman, Sulaiman Ibrahim Alsugair, Hadeel Adel Alsulimani

“…The findings of this study remain inconclusive due to significant heterogeneity and underscore the need for comprehensive and well-structured primary studies to gather strong evidence.…”
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Development of a Method for Obtaining Nanoscale Magnesium Carbonate Stabilized with Chitosan as the Basis of Scaffold Matrices for Regenerative Medicine by A. V. Blinov, Z. A. Rekhman, A. A. Gvozdenko, M. A. Yasnaya, M. A. Kolodkin, M. A. Taravanov

“…The creation of three-dimensional matrices based on scaffolds for the formation of systems that are as close as possible to bone tissue in structure has been studied. It is known that the active substances of the scaffold matrix can be hydroxyapatite, tricalcium phosphate, as well as silicates, carbonates of magnesium, calcium, copper, zinc, and manganese. …”
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Beyond the classroom: how parents view motivation as a key to self-directed learning in township schools by Tebogo Siziba, Tebogo Siziba, Bernadette Geduld, Bernadette Geduld, Charlene Du Toit-Brits, Charlene Du Toit-Brits

“…Using a purpose-orientated and convenient sampling, 10 parents or guardians of two schools in Gauteng were selected. Semi-structured face-to-face interviews facilitated data collection and inductive thematic analysis was used. …”
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Assessment of smoking cessation outcomes in patients with cardiovascular disease: A retrospective cohort study from Türkiye by Yagmur Gokseven Arda, Guzin Zeren Ozturk

“…A CVD diagnosis alone did not significantly enhance success, highlighting the need for tailored behavioral support and structured follow-up. Optimizing cessation programs with individualized interventions may improve outcomes, particularly in high-risk CVD patients.…”
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Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study. by Xue Li, Xiangrui Meng, Yazhou He, Athina Spiliopoulou, Maria Timofeeva, Wei-Qi Wei, Aliya Gifford, Tian Yang, Tim Varley, Ioanna Tzoulaki, Peter Joshi, Joshua C Denny, Paul Mckeigue, Harry Campbell, Evropi Theodoratou

“…<h4>Methods and findings</h4>A phenome-wide association study (PheWAS) together with a Bayesian analysis of tree-structured phenotypic model (TreeWAS) was performed to examine disease outcomes related to genetically determined serum urate levels in 339,256 unrelated White British individuals (54% female) in the UK Biobank who were aged 40-69 years (mean age, 56.87; SD, 7.99) when recruited from 2006 to 2010. …”
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Analysis of Factors Influencing Adoption of Human Resource Practices by Small and Medium Scale Enterprises in Nigeria by Rukayat Oloruntoyin Rabiu, Wahid Damilola Olanipekun, Ayodeji Gbenga Bamidele, Olasehinde Israel Awe

“…The factors influencing the use of human resources by small and medium scale enterprises in the article are studied in the following logical sequence: using a structured questionnaire developed in the form of the Rensis Likert scale, an array of primary data is forme. …”
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Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China by Huan Zhang, Su Dong, Caiping Mao, Yuejuan Fang, Junjie Ying

“…The antimicrobial susceptibility testing data revealed that KPZM16 possesses an extensively drug-resistant (XDR) profile, whereas KPZM6 is a susceptible K. pneumoniae. …”
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Evaluation of tissue computed tomography number changes and dosimetric shifts after conventional whole-breast irradiation in patients undergoing breast-conserving surgery by Joo Hwan Lee, Dong Soo Lee, So Hyun Park, Young Kyu Lee, Jeong Soo Kim, Yong Seok Kim

“…Dosimetric parameters (V 105% , V 103% , V 100% , V 98% , V 95% , V 90% : V x% indicates volumes which receive X% of prescribed doses) between initial and re-sim CT scans were compared. The CT number data (CT mean , CT max , CT min ) of the original and irradiated CT (re-sim CT) scans from each representative structure (lung, rib bone, soft tissue, muscle, etc.) were examined and recruited. …”
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Treatment Outcome of Epileptic Patients Receiving Antiepileptic Drugs in Ethiopia: A Systematic Review and Meta-Analysis by Taklo Simeneh Yazie, Belayneh Kefale, Mulugeta Molla

“…A systematic literature search was conducted using PubMed/Medline, Science Direct, PsycINFO, Hinnarri databases, and Google Scholar for grey literatures. Data were extracted with structured format prepared using Microsoft Excel and exported to Stata/MP 16.0 software for analyses. …”
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Translation and Validation of Family Stigma Stress Scale (FSSS) Among Caregivers of Patients With Mental Illness in Pakistan by Rabia Khawar, Imtiaz Ahmad Dogar, Mehwish Shakil, Samavia Hussain, Ammara Butt, Rizwana Amin, Hafiz Shafique Ahmad, Bushra Akram, Ayesha Sheraz, Hira Ahmad, Memoona Aslam

“…Data were analysed through SPSS version 26 and AMOS version 24. …”
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SELECTION CRITERIA OF COMPOUNDS FOR DEVELOPMENT OF HIGH-POTENT ANALGESICS AND OTHER CNS DRUGS by A. V. Sosnov, F. M. Semchenko, V. N. Tohmahchi, A. A. Sosnova, M. I. Vlasov, A. S. Radilov, D. V. Krivorotov

“…In order to analyze best practices, develop a strategy for highly effective controlled medicinal and veterinary drugs (analgesics, anesthetics, antidotes and other vital therapies) and coordinate theirdevelopment and production it is necessary to create competent management structure combining the tasks of provision of civilian population and personnel of national defense agencies of effective and safe drugs.…”
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Challenges and needs in the management of non-alcoholic fatty liver disease from the perspective of gastroenterology and hepatology specialists: a qualitative study by Farzad Salmanizadeh, Sakineh Sabzevari, Sara Shafieipour, Mohammad Javad Zahedi, Afshin Sarafinejad

“…Fifteen Iranian GH specialists selected by purposive sampling. Data were collected through semi-structured interviews. …”
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Genome-Wide Association Study for Belly Traits in Canadian Commercial Crossbred Pigs by Zohre Mozduri, Graham Plastow, Jack Dekkers, Kerry Houlahan, Robert Kemp, Manuel Juárez

“…To identify quantitative trait loci (QTLs) and genes linked to key carcass traits, we conducted a genome-wide association study (GWAS) using whole-genome sequencing data from 1118 commercial pigs (Duroc sires and Yorkshire/Landrace F1 dams). …”
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The Effect of Maternal Attitudes and Depression on Bonding During the Postpartum Period by Şenyaşar Meterelliyoz K, Çağlar Mengi K, Yazar MS, Akbay Kısa AS

“…The findings indicated that an individual with a psychiatric diagnosis was 2.653 times more likely to exhibit impaired bonding (OR: 2.653, 95% CI: [1.08– 6.517]; p = 0.033), and those with a higher AToM score were 1.044 times more likely to display impaired bonding (OR: 1.044, 95% CI: [1.013– 1.075]; p = 0.004).Conclusion: The cognitive structure of the mother is associated with impaired mother-baby bonding. …”
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Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation... by Daren K Heyland, Andrew Day, G John Clarke, Catherine (Terri) Hough, D Clark Files, Marina Mourtzakis, Nicolaas Deutz, Dale M Needham, Renee Stapleton

“…Compared with standard of care, the benefits of greater protein intake combined with structured exercise started early after the onset of critical illness remain uncertain. …”
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Predictors of vitamin D status in undernourished and well-nourished children 6–59 months old, in the JB Marks Municipality of South Africa by JA Carboo, L Malan, M Lombard, N Maleka, A Nienaber, R Claire Dolman-Macleod

“…Objective: to investigate the predictors of vitamin D (vitD) status of undernourished and well-nourished children aged under five years in the North West Province of South Africa.Design: this cross-sectional study assessed sociodemographic data, nutritional supplement intake, vitD-rich food consumption, and sunlight exposure via a structured questionnaire. …”
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The Eagle Eyes: an Intervention Utilizing Visual Thinking Strategies to Enhance the Observation Skills of Medical Students by Najmeh Ghorbani, Maryam Alizadeh, Azadeh Sayarifard, Abdoljavad Khajavi, Philip Yenawine

“…Abstract Background Visual Thinking Strategies (VTS) is an evidence-based pedagogical approach that uses art analysis and structured inquiry to enhance observation, critical thinking, and teamwork, especially in medical training for clinical skills development. …”
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