Novel Dural Opening Technique in Intradural Extramedullary Tumors at the Craniovertebral Junction: Three-Year Single-Center Experience by Giovanni Federico Nicoletti, Francesca Graziano, Federica Paolini, Roberta Costanzo, Manikon Poullay Silven, Massimo Furnari, Domenico Gerardo Iacopino, Rosario Maugeri, Bipin Chaurasia, Gianluca Ferini, Giuseppe Emmanuele Umana, Gianluca Scalia

“…<b>Background/Objectives:</b> The craniovertebral junction (CVJ) poses unique challenges in the surgical management of intradural extramedullary (IDEM) tumors due to its complex anatomy and proximity to critical neurovascular structures. This study presents a comprehensive review of a single center’s experience over three years in managing IDEM tumors at the CVJ, emphasizing a novel approach to dural opening aimed at improving surgical access and patient outcomes. …”
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Design and methods of an adaptive trial to test comparative effectiveness of readmission reduction approaches following infection and sepsis hospitalizations (ACCOMPLISH) by Kristin Mayes, Victor B. Talisa, Adelina Malito, Florian B. Mayr, Kelly Williams, Kalpana Char, Richard Wadas, Elizabeth Lorenzi, Kert Viele, Rana Awdish, Derek C. Angus, Chung-Chou Ho Chang, Sachin Yende

“…Methods: Adults admitted to the hospital with sepsis or lower respiratory tract infection (index admission) are recruited and randomized to usual care (structured telephonic support [STS]) or one of four post-discharge RPM care models in addition to STS. …”
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Implementation of a Patient Navigation Program to Support Representative Participation in Cancer Clinical Trials by Sukh Makhnoon, Fabian Robles, Jessica L. Lee, D'Angelo Grant, Marisol Rojas, Ang Gao, Carla Pezzia, Venkata Eluri, Navid Sadeghi, Song Zhang, Thomas Hulsey, Rebecca Renn, Erin L. Williams, Heather Kitzman, David E. Gerber

“…Evaluation was guided by the Reach, Effectiveness, Adoption, Implementation, and Maintenance framework and incorporated programmatic data, structured surveys of patients and staff, and qualitative patient interviews. …”
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Thalamus and consciousness: a systematic review on thalamic nuclei associated with consciousness by Martina Cacciatore, Francesca Giulia Magnani, Filippo Barbadoro, Camilla Ippoliti, Mario Stanziano, Mario Stanziano, Letizia Clementi, Anna Nigri, Lorenzo Nanetti, Silvia Marino, Fabio La Porta, Lucia Francesca Lucca, Francesco Prada, Francesco Prada, Matilde Leonardi

“…IntroductionConsciousness relies on both cortical and subcortical structures and their feedforward and feedback pathways. …”
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Australian treatment outcome study: protocol for the 18–20-year follow-up of a prospective longitudinal cohort examining the natural history of heroin dependence and associated mor... by Maree Teesson, Paul S Haber, Christina Marel, Katherine Mills, Rachel Visontay, Jack Wilson, Shane Darke, Joanne Ross, Tim Slade, Katherine Haasnoot, Madeleine Keaveny, Chris Tremonti

“…The 18–20-year follow-up will consist of: (1) a structured interview; (2) physical health assessment; and (3) data linkage. …”
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Prevalence of tick-borne pathogens in feeding and questing Ixodes ricinus ticks from Southern Sweden by Chiara Cialini, Alessandra Cafiso, Mattias Waldeck, Åsa Lundgren, Johan Fält, Bo Settergren, Phimphanit Choklikitumnuey, Giulia Chiappa, Eleonora Rosso, Laura Roveri, Elisa Fesce, Nicola Ferrari, Per-Eric Lindgren, Chiara Bazzocchi, Giulio Grandi

“…This study highlights the presence of several zoonotic TBPs in Skåne, emphasizing the need for a structured monitoring plan and preventive strategies within a One Health framework.…”
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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

“…In this study, participants who underwent free cataract surgery between January and August 2014 received a telephone interview based on a structured questionnaire. Data were collected on patient demographics, resources, health conditions, reasons for undergoing the free surgery and overall evaluation of the free cataract surgery programme.Results Among the 833 participants, the mean surgical age was 76.85±7.46 years (95% CI 76.34 to 77.36), and the male to female ratio was 385:448. …”
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Research on the Protection Status and Development Strategies for New Varieties of Lychee and Longan in China by Yingjie WEN, Zhixian TANG, Fachao SHI, Hailun LIU, Yonghua JIANG, Qian YAN

“…These include outdated breeding techniques, a lack of diversity in breeding entity structures, inefficiencies in variety conversion, and complexities within the technical and legal dimensions of variety protection. …”
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OrthoticS for TReatment of symptomatic flat feet In CHildren (OSTRICH): a randomised controlled trial by Sarah Cockayne, Kalpita Baird, Sally Gates, Caroline Fairhurst, Joy Adamson, Rachel M Bottomley-Wise, Amie Woodward, Michael R Backhouse, Rachel Bye, Nina Davies, Catherine Hewitt, Colin Holton, Peter Knapp, Anne-Maree Keenan, Stewart Morrison, Daniel Parker, Daniel C Perry, Sarah Ronaldson, Mark Smith, Tim Theologis, Victoria Exley, Jane McAdam, David J Torgerson

“…Limitations We could not deliver the study objectives as planned. Due to the limited data available, we were unable to undertake the planned analysis. …”
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Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

“…Quantitative data were analyzed using descriptive statistics. …”
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O-prenylchalcones inhibit cell proliferation and activate apoptosis by inducing mitochondrial dysfunction in gastric cancer cells by José C. Espinoza-Hicks, Yarely M. Salinas-Vera, Javier Camarillo-Cisneros, Alejandro A. Camacho-Dávila, Jessica L. Hernández-Rivera, Nadia Flores-Huerta, Eloisa Ibarra-Sierra, Carlos Pérez-Plasencia, María Elizbeth Álvarez-Sánchez, Ángeles C. Tecalco-Cruz, César López-Camarillo

“…The interactions between the O-prenylchalcones and selected oncoproteins were predicted by first identifying the most stable conformers, and approximately 5,000 structures were evaluated by force field molecular dynamics. …”
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Feasibility of a tailored, combined intervention with mind-body elements to prevent burnout in healthcare professionals (LAGOM) in a mixed-methods multicenter single-arm trial by Marleen Schröter, Anna K. Koch, Julia Berschick, Julia K. Schiele, Martin Bogdanski, Melanie Steinmetz, Judith Czakert, Wiebke Stritter, Christian S. Kessler, Georg Seifert

“…The feasibility of electrophysiological measures like pulse and respiration activity was assessed. Semi-structured interviews with a subgroup were qualitatively analyzed following a qualitative content analysis approach. …”
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Factors Influencing Measles Vaccine Compliance: A Descriptive-correlational Study in Barangay C, Northern Mindanao by Rhy Kenji Enguio, Zenju Espinosa, Ashley Jenn Fallarna, Ferdinand Gabriel Galarrita, Justine Jean Guillermo, Jasimah Gutoc, Rhea Mae Janolino, Aleks Jimenez, Kayle Mae Labasano, Jade Godwin Lagua, Ariel Lacdo-O, Edmund Zheen Regor Moreno, Paolo Araune, Ivy Go

“…Materials and Methods: This study utilized a non-experimental quantitative descriptive design to examine factors influencing measles vaccination compliance among residents of barangay C. The study data were collected using a structured survey questionnaire that served as the instrument designed to measure compliance across psychosocial factors and behavioral-specific cognitions. …”
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Chronic unilateral vestibular hypofunction: a qualitative study exploring the full spectrum of symptoms and impacts through the ICF framework by Mustafa Karabulut, Hamide Avci, Eda Yalçınkaya, Merel Kimman, Wolfgang Viechtbauer, Alfarghal Mohamad, Vincent Van Rompaey, Nils Guinand, Angélica Perez Fornos, Levent Özlüoğlu, Osman Nuri Özgirgin, Raymond van de Berg

“…Data collection continued until thematic saturation was reached. …”
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Enhancing nurses’ communication about psychosocial needs and changes in intimacy and sexuality in patients with advanced cancer: a mixed-method study by Susanne A.M. Arends, Corien M. Eeltink, Floortje K. Ploos van Amstel, Astrid W. Oosten, Donna C. Ruijter, Nelleke van der Loo, Barbara Harterink-Poker, Anneke L. Francke, Irene P. Jongerden

“…Perceived competences and documentation regarding communication about psychosocial needs were determined using a survey questionnaire, patient record screening, and semi-structured interviews with nurses. Results: In total 53 hospital nurses participated in the training. …”
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Seroprevalence of anti-SARS-CoV-2 antibodies and risk of viral exposure among healthcare workers in the South Kivu province, eastern Democratic Republic of the Congo: a cross-secti... by Denis Mukwege, Andreas Kalk, Tim Eckmanns, Andreas Nitsche, Fabian H Leendertz, Tshass B Chasinga, Jean-Paul Buhendwa Cikwanine, Sarah Kribi, Jonathan Tunangoya Yoyu, Natalie Hofmann, Marica Grossegesse, Sara Tomczyk, Ann C Vietor, Aline B Kusinza, Eric Munguakonkwa, Maroyi Raha, Nelson S Kambale, Rodrigue B Ayagirwe, Grit Schubert

“…The present study aims to measure the impact of SARS-CoV-2 on HCWs in central sub-Saharan Africa.Setting A cross-sectional serological study was conducted at six urban and five rural hospitals during the first pandemic wave in the South Kivu province, Democratic Republic of the Congo (DRC).Participants Serum specimens from 1029 HCWs employed during the first pandemic wave were collected between August and October 2020, and data on demographics and work-related factors were recorded during structured interviews.Primary and secondary outcome measures The presence of IgG antibodies against SARS-CoV-2 was examined by ELISA. …”
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Complementary medicine among individuals experiencing homelessness in Switzerland: a quantitative and qualitative descriptive study by Véronique S. Grazioli, Evelyne Hangartner, Patrick Bodenmann, Luana Schaad, Léa Grosjean, Justin Nikles, David J. T. Campbell, Laurent Hyvert, Tshahé Anongba Varela, Susan E. Collins, Caroline Leblanc, Christine Loignon, Chantal Berna

“…A subsample of the survey participants (n = 18) and 14 professionals working in the homeless-serving sector participated in semi-structured interviews exploring perceived utility of CM for PEH. …”
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The antioxidant property of CAPE depends on TRPV1 channel activation in microvascular endothelial cells by Miltha Hidalgo, Bárbara Railef, Vania Rodríguez, Carolina Navarro, Vanessa Rubio, Jorge Meneses-Pacheco, Sandra Soto-Alarcón, Christine Kreindl, Carolina Añazco, Leandro Zuñiga, Omar Porras

“…Herein, we hypothesized that a subfamily of TRP ion channels works as the molecular entity that recognizes CAPE at the plasma membrane and allows a fast shift in the antioxidant capacity of intact endothelial cells (EC).By monitoring cytoplasmic Ca2+ in a microvascular EC model, we compared the calcium responses evoked by three structurally related compounds: caffeic acid phenethyl ester, neochlorogenic acid and caffeic acid. …”
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MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study by Jefree Johari, Robert D. Hontz, Brian L. Pike, Tupur Husain, Norhayati Rusli, Rozainanee Mohd-Zain, Vunjia Tiong, Hai-Yen Lee, Boon-Teong Teoh, Sing-Sin Sam, Chee-Sieng Khor, Shih-Keng Loong, Juraina Abd-Jamil, Siti-Sarah Nor'e, Hasmawati Yahaya, Naim Che-Kamaruddin, Jose A. Garcia-Rivera, Sazaly AbuBakar

“…ELISAs and micro-neutralization assays were performed to detect the presence of MERS-CoV IgG antibodies. Sociodemographic data, symptoms experienced during Hajj, and history of exposure to camels or camel products were recorded using structured pre- and post-Hajj questionnaires. …”
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Traditional uses and importance of Strychnos L. (Loganiaceae): A cross-cultural and spatial variation study in Benin by Donald Djidohokpin, Gbèwonmèdéa Hospice Dassou, Gnimansou Abraham Favi, Octave Mathieu Zountangni, Jéronime Marie-Ange Sènami Ouachinou, Judicael Makponsè, Ghyslain Kpetikou, Gbèkponhami Monique Tossou, Hounnankpon Yédomonhan, Aristide Cossi Adomou

“…Detailed information about uses and homemade herbal remedies regarding the medicinal category was collected. Data were analyzed through the citation frequencies and homemade remedy report (HR) using Excel. …”
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