Contextual factors in value-based decision support to enhance health technologies adoption: the case of biosimilars by Maximilian Otte, Maximilian Otte, Maximilian Otte, Zoltán Kaló, Zoltán Kaló, Zoltán Kaló, Hussain Abdulrahman Al-Omar, Meindert Boysen, Yingyao Chen, Ana Paula Beck Da Silva Etges, Ana Paula Beck Da Silva Etges, Guvenc Kockaya, Iñaki Gutierrez-Ibarluzea, Ahmed Mohammed Seyam, Deirdre Mullen, Deirdre Mullen, Hans-Peter Dauben, Hans-Peter Dauben, Hans-Peter Dauben

“…The MCDA framework offers a structured approach to operationalize these principles. …”
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Orthopaedic Consultation is Associated With Fewer Patient-Perceived Barriers to Total Joint Arthroplasty by Insa Mannstadt, BS, BA, J. Alex B. Gibbons, BA, Troy B. Amen, MD, MBA, Mangala Rajan, PhD, Sarah R. Young, PhD, Henry Tischler, MD, Michael L. Parks, MD, Mark Figgie, MD, Anne Bass, MD, Linda Russell, MD, Bella Mehta, MD, MS, Iris Navarro-Millán, MD, Susan M. Goodman, MD

“…Methods: We performed a post-hoc analysis of questionnaire responses based on data from a previous study that used semi-structured interviews with patients with advanced osteoarthritis. …”
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Inaccuracies of venous thromboembolism risk assessment and prevention practices among medically ill patients by Brandyn D. Lau, Aditya Bhave, Jennifer C. Yui, Rakhi Naik, Kathryn E. Dane, John Lindsley, Dauryne L. Shaffer, Peggy S. Kraus, Erik H. Hoyer, Elliott R. Haut, Michael B. Streiff

“…Leveraging existing structured data to autopopulate VTE risk assessments can assist providers in improving accuracy. …”
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METASOMATIC AND MAGMATIC PROCESSES IN THE MANTLE LITHOSPHERE OF THE BIREKTE TERRAIN OF THE SIBERIAN CRATON AND THEIR EFFECT ON THE LITHOSPHERE EVOLUTION by Lidia V. Solov’eva, Tatiana V. Kalashnikova, Sergei I. Kostrovitsky, Alexei V. Ivanov, Stanislav S. Matsuk, Ludmila F. Suvorova

“…Mica and ilmenite contents sharply decrease in garnetized xenolithes, where these two minerals, as soon as olivine and pyroxenes are replaced by garnet.Euhedral, subhedral, sideronitic and porphyraceous structures in garnetless xenoliths suggest the primary magmatic genesis of the rocks. …”
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An indoor air pollution research strategy for the United Arab Emirates by Jacqueline MacDonald Gibson, Rahaf Ajaj, Ahmed Al Khazraji, Latifa Al Shamsi, William P. Bahnfleth, Daniel Bonn, Katherine Bronstein, Rania Dghaim, Taher Eldanaf, Mohamed El Sadig, Moshood Olawale Fadeyi, Diana Francis, Grace Kilroy, Samrin Ahmed Kusum, Yuguo Li, Amal Mubarak Madhi, Mily Mathew, Shelly L. Miller, Jordan Peccia, Driss Samri, Riad Saraiji, Pawel Wargocki, Fares H. Zaitoun, MD

“…UAE summer temperatures routinely exceed 42°C (108°F), discouraging outdoor activity and limiting natural ventilation of structures. Yet, little research is available on indoor air quality in the UAE. …”
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Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease by Zachary Gaertner, Cameron Oram, Amanda Schneeweis, Elan Schonfeld, Cyril Bolduc, Chuyu Chen, Daniel Dombeck, Loukia Parisiadou, Jean-Francois Poulin, Rajeshwar Awatramani

“…We developed an optimized pipeline for single-nuclear RNA sequencing (snRNA-seq) and generated a high-resolution hierarchically organized map revealing 20 molecularly distinct DA neuron subtypes belonging to three main families. We integrated this data with spatial MERFISH technology to map, with high definition, the location of these subtypes in the mouse midbrain, revealing heterogeneity even within neuroanatomical sub-structures. …”
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Physical activity, screen time, and sleep quality of students during remote learning by Elias dos Santos Batista, Helder Xavier Bezerra, Gabriel Pereira Maciel, Alesandra Araújo de Souza, Marcela Rodrigues de Castro, Valter Cordeiro Barbosa Filho, Rodrigo Ramalho Aniceto

“…An online questionnaire was structured, including recall information about behaviors before and during remote learning. …”
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De Novo Reconstruction of 3D Human Facial Images from DNA Sequence by Mingqi Jiao, Jiarui Li, Bingxu Zhong, Siyuan Du, Shuning Li, Manfei Zhang, Qibin Zhang, Zhongming Liang, Fan Liu, Chunman Zuo, Sijia Wang, Luonan Chen

“…Difface can generate 3D facial images of individuals solely from their DNA data, projecting their appearance at various future ages. …”
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Ultradiffuse Dwarf Galaxies Hosting Pseudobulges by Yu Rong, Hong-Xin Zhang, Cheng Cheng, Qi Guo, Weiyu Ding, Zichen Hua, Huiyuan Wang, Xu Kong

“…By analyzing data from DESI Legacy Imaging Survey of the dwarf galaxies in the Arecibo Legacy Fast Alfa Survey, we have identified five ultradiffuse galaxies (UDGs) featuring central pseudobulges. …”
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The role of offensive and creative priming videos in enhancing youth football players’ performance during small-sided games by Diogo Coutinho, Diogo Coutinho, Bruno Gonçalves, Bruno Gonçalves, Sara Santos, Sara Santos, Sigrid Olthof, Rafael Ballester Lengua, André Roca, Bruno Travassos, Bruno Travassos, Bruno Travassos

“…Coaches can leverage offensive priming to improve structured passing and positioning, while creative priming may inspire exploratory movements and innovative shooting attempts.…”
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Transition from child to adult health services for young people with cerebral palsy in Ireland; implications from a mixed-methods study [version 2; peer review: 2 approved] by Owen Hensey, Amanda Breen, Aisling Walsh, Mary Owens, Claire Kerr, Sebastian Koppe, Grace Lavelle, Meriel Norris, Michael Walsh, Jennifer M. Ryan, Thilo Kroll, Jennifer Fortune

“…Methods A convergent parallel mixed-methods study was conducted. Data were collected from people with cerebral palsy aged 16–22 years, parents, and health professionals using surveys and semi-structured interviews, which were both informed by a framework of nine key transition practices. …”
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Investigation of an extensive outbreak of HIV infection among children in Sindh, Pakistan: protocol for a matched case–control study by Victoria Simms, Rashida Ferrand, Baseer Achakzai, Iqbal Azam, Amna R Siddiqui, Apsara Ali Nathwani, Syed H Abidi, Syed Faisal Mahmood, Sobiya Sawani, Abdul M Kazi, Aneeta Hotwani, Sikander Ali Memon, Jamila Soomro, Saqib Ali Shaikh, Quaid Saeed, Palwasha Khan, Fatima Mir

“…Following written informed consent from the guardian, a structured questionnaire will be administered to collect data on sociodemographic indices and exposure to risk factors for parenteral, vertical and sexual (only among those aged above 10 years) HIV transmission. …”
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Optimising Paediatric Transition to Intensive Care for Adults (OPTICAL): study protocol for a mixed method study by Padmanabhan Ramnarayan, Louise Rose, Julie Taylor, Christina Pagel, Jo Wray, Sarah E Seaton, Kate Oulton, Sonya Crowe, Rum Thomas, Qi Huang, Paul R Mouncey, Katherine Malbon, Anjalika Mallick, Charmaine Kohn, Sue Ben Abraham, Clare Windsor

“…To do this, we will: (1) link and analyse UK national data (years 2017–2024) on paediatric and adult ICU admissions, hospital inpatient, outpatient and emergency care visits and survival status, to determine the clinical characteristics and healthcare resource utilisation from teenage years to early adulthood of people admitted to an ICU as a young person (admission aged 14 and 15), and how these relate to ICU admissions after age 16; (2) conduct semistructured interviews, online forums and surveys with TYA patients, carers and health professionals to understand their experience of transition in ICU services; and (3) synthesise these strands of evidence and use a structured process of stakeholder engagement to propose potential targeted improvements as appropriate.Ethics and dissemination This study was approved by the East of England - Cambridge South Research Ethics Committee on 1 August 2024 (research ethics committee number 24/EE/0108), and the Health Research Authority Confidentiality Advisory Group (CAG) on 7 October 2024 (CAG number 24/CAG/0068). …”
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Vulvovaginal candidiasis: knowledge, practices and occurrence among pregnant women receiving antenatal care in a teaching hospital, Ghana by Florence Shine Edziah, Florence Shine Edziah, Princess Ruhama Acheampong, Philip Apraku Tawiah, Cedric Dzidzor Amengor, Godsway Edem Kpene, Grace Otobea Amponsah, Priscilla Appiah Baffoe, Georgina Korankye, John Gameli Deku

“…This study assessed the knowledge, practices and occurrence of Vulvovaginal candidiasis among pregnant women accessing antenatal care at a teaching hospital in Ghana.MethodsA cross-sectional study was conducted among 336 pregnant women receiving antenatal care at the Ho Teaching Hospital. A structured questionnaire was used to assess their knowledge of the infection and practices on vaginal hygiene. …”
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The experience of immersive virtual reality in patients with heart failure during cardiac rehabilitation: a qualitative study by Valentina Micheluzzi, Valentina Micheluzzi, Gavino Casu, Gavino Casu, Francesco Burrai, Antonella Canu, Antonio Sircana, Pierluigi Merella, Pierluigi Merella, Angelo Laconi, Angelo Laconi, Andrea Chelo, Andrea Chelo, Piero Cozzula, Michela Piredda, Ercole Vellone, Ercole Vellone

“…The intervention group experienced iVR in natural settings, while the control group received standard care. Semi-structured individual interviews were conducted in person after the intervention group’s eighth rehabilitation session. …”
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Сontent of cytokines and growth factors in the intraocular fluid of patients with primary open-angle glaucoma by V. V. Chernykh, V. I. Konenkov, O. V. Ermakova, N. B. Orlov, O. O. Obukhova, A. V. Eremina, A. N. Trunov

“…Increase concentrations of IL-7 in the intraocular fluid of patients with primary open-angle glaucoma allows us to assume participation in the pathogenesis of the primary open-angle glaucoma of this autocrine mediator of activation of the growth of lymphatic structures.…”
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Strengthening neonatal care through ward assistants: a Kenyan case study in enhancing infection prevention and control practices by Michuki Maina, Nancy Odinga, Vincent Kagonya, Gloria Ngaiza, Sebastian Fuller, Onesmus Onyango, Caroline Waithira, Dorothy Oluoch, David Gathara, Peter Mwangi, Loise Mwangi, Penina Musyoka, Lucy Kinyua, Lydia Thuranira, Virginia Njoroge, Ngina Mwangi, Zainab Kioni, Mike English, Edna Mutua

“…Methods This study employed a mixed methods approach in four public neonatal units in Kenya to assess the impact of deploying ward assistants on IPC practices. Data collection included structured and unstructured observations, in-depth interviews, and focus group discussions with healthcare workers and caregivers. …”
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Experiences and perceptions of Chinese patients enrolled in a clinical trial assessing tuina and manual therapies for knee osteoarthritis: a nested qualitative study by Luping Liu, Lingyun Zhang, Sina Li, Meiling Cai, Siyu Han, Zhiwen Weng, Qianji Chen, Yixuan Gao, Xiaoming Yang, Yang Zhang, Duoduo Li, Changxin Liu, Ya’nan Sun, Xiyou Wang, Changhe Yu

“…The interviews were conducted by two researchers who have extensive experience interviewing KOA patients, and data were gathered through face-to-face, semi-structured interviews to ensure a high level of information power. …”
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Effects of timely case conferencing between general practitioners and specialist palliative care services on symptom burden in patients with advanced chronic disease: results of th... by Tina Mallon, Josefine Schulze, Nadine Pohontsch, Thomas Asendorf, Jan Weber, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Judith Dams, Michael Freitag, Christiane Müller, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx

“…Methods The cluster-randomised controlled trial compared a structured palliative care nurse visit followed by an interprofessional case conference to usual care. …”
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Molecular characterization of carbapenem-resistant and virulent plasmids in Klebsiella pneumoniae from patients with bloodstream infections in China by Yongqiang Yang, Yanxian Yang, Guanping Chen, Minmin Lin, Yuan Chen, Ruowen He, Klibs N. Galvão, Mohamed Abd El-Gawad El-Sayed Ahmed, Adam P. Roberts, Yiping Wu, Lan-Lan Zhong, Xiaoxue Liang, Mingyang Qin, Xin Ding, Wenbin Deng, Songyin Huang, Hong-Yu Li, Min Dai, Ding-Qiang Chen, Liyan Zhang, Kang Liao, Yong Xia, Guo-Bao Tian

“…We described 29 KPC-2 plasmids showing diverse structures, two virulence plasmids in two KPC-2-producing Kp, and two novel multidrug-resistant (MDR)-virulent plasmids. …”
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