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  1. 64541
  2. 64542
  3. 64543
  4. 64544

    HOTSED: A new integrated model for assessing potential hotspots of sediment sources and related sediment dynamics at watershed scale by Manuel La Licata, Alberto Bosino, Seyed Hamidreza Sadeghi, Mattia De Amicis, Andrea Mandarino, Andrea Terret, Michael Maerker

    Published 2025-03-01
    “…Subsequently, we used data stored in the IM to estimate the geomorphic Potential of Sediment Sources (PSS) through a relative scoring system. …”
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  5. 64545
  6. 64546
  7. 64547

    The impact of circWWC3 on neoadjuvant therapy for triple-negative breast cancer and the construction of a nomogram for predicting pathological complete response after neoadjuvant t... by Haoqi Wang, Haoqi Wang, Hongbo Liu, Hongbo Liu, Shan Gao, Lijia Wang, Zihao Bai, Yi Zhang, Peijin Zhang, Fei Liu, Fei Liu, Cuizhi Geng, Cuizhi Geng

    Published 2025-07-01
    “…Therefore, it is crucial to identify new molecular targets for precise treatment and to develop predictive models for pCR to facilitate tailored therapeutic approaches.MethodsWe conducted a study involving a cohort of TNBC patients who underwent NAT, collecting data on clinicopathological indicators, MRI parameters, and pathological remission outcomes. …”
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  8. 64548
  9. 64549

    Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice by Victor J. Johnson, Cynthia V. Rider, Michael I. Luster, Cynthia J. Willson, Shawn Harris, Billie Stiffler, James Blake, Esra Mutlu, Veronica Godfrey, Brian Burback, Reshan Fernando, Suramya Waidyanatha, Gary R. Burleson, Dori R. Germolec

    Published 2025-03-01
    “…Additionally, there are several weaknesses in existing immunotoxicity databases for PACs in experimental animals, limiting their applicability in quantitative risk assessment. Careful characterization of strong positive and clear negative PACs is needed in order to lay the foundation for generating robust immunotoxicity data for structurally diverse PACs that have not yet been evaluated.MethodsIn the current study, adult B6C3F1/N female mice were treated daily for 28 consecutive days by oral administration of B(a)P to provide dose levels ranging between 2 and 150 mg/kg bodyweight/day. …”
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  10. 64550
  11. 64551

    Factors influencing public health engagement in alcohol licensing in England and Scotland including legal and structural differences: comparative interview analysis by Niamh Fitzgerald, Andrea Mohan, Richard Purves, Rachel O’Donnell, Matt Egan, James Nicholls, Nason Maani, Maria Smolar, Andrew Fraser, Tim Briton, Laura Mahon

    Published 2024-02-01
    “…They were less likely to try to block applications. When they agreed changes to applications with businesses instead of objecting, fewer formal licensing meetings were needed. …”
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  12. 64552

    Association of the atherogenic index of plasma and high-sensitivity C-reactive protein with incident cardiovascular disease: evidence from a national cohort of middle-aged and olde... by Ping-an Lian, Fei Xie, Wei Zhang, Shuai Cheng, Yun-fei Zhao, Lin Li, Shan-fu Liang, Zhan-zhan Zhu, Jun-yue Zhang, Jiao-jiao Cui, Jie Du, Lei Yin, Shen-wei Zhang

    Published 2025-08-01
    “…BackgroundThe atherogenic index of plasma (AIP), an emerging biomarker of lipid dysregulation, and high-sensitivity C-reactive protein (hs-CRP), an established marker of inflammation, are both implicated in the development of cardiovascular disease (CVD). …”
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  13. 64553
  14. 64554

    Gut bacteria Prevotellaceae related lithocholic acid metabolism promotes colonic inflammation by Liping Chen, Zhenghao Ye, Junhua Li, Lijia Wang, Yu Chen, Meiping Yu, Jian Han, Jiangeng Huang, Dongyan Li, Yongling Lv, Kai Xiong, De’an Tian, Jiazhi Liao, Ursula Seidler, Fang Xiao

    Published 2025-01-01
    “…Analysis of the microbiome and metagenomic data revealed changes in the gut microbiota, notably an increased abundance of an unclassified genus within the family Prevotellaceae in DSS-induced colitis mice. …”
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  15. 64555
  16. 64556

    Haplotype-resolved assemblies of the MHC region in five widely used tumor cell lines by Haozhe Yuan, Mengping Jiang, Xingyu Xu, Jialiang Zhu, Shulong Dong, Weida Meng, Dandan Zhang, Jiakang Ma, Yicheng Lin, Ziqiang Chen, Shaoyang Sun, Wenqing Qiu, Yun Liu

    Published 2025-09-01
    “…The major histocompatibility complex (MHC) region plays a crucial role in immune function and is implicated in various diseases and cancer immunoediting. …”
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  17. 64557

    Three-dimensional direct lithography of stable quantum dots in hybrid glass by Dezhi Zhu, Shangben Jiang, Ying Wang, Dejun Liu, Weijia Bao, Liwei Liu, Junle Qu, Yiping Wang, Changrui Liao

    Published 2025-01-01
    “…Based on hybrid 3D nanolithography, bicolor multilayer micro-/nano- structures are manufactured for applications in 3D data storage and optical information encryption. …”
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  18. 64558

    Peripheral blood immune cells from individuals with Parkinson's disease or inflammatory bowel disease share deficits in iron storage and transport that are modulated by non-steroid... by MacKenzie L. Bolen, Beatriz Nuñes Gomes, Blake Gill, Kelly B. Menees, Hannah Staley, Janna Jernigan, Nikolaus R. McFarland, Ellen M. Zimmermann, Christopher E. Forsmark, Malú Gámez Tansey

    Published 2025-04-01
    “…Additionally, this communication can be modulated by several environmental factors; specifically, our data further support existing literature demonstrating a role for non-steroidal anti-inflammatory drugs (NSAIDs) in modulating immune transcriptional states in inflamed individuals. …”
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  19. 64559

    Association between genetically proxied PCSK9 inhibition and prostate cancer risk: A Mendelian randomisation study. by Si Fang, James Yarmolinsky, Dipender Gill, Caroline J Bull, Claire M Perks, PRACTICAL Consortium, George Davey Smith, Tom R Gaunt, Tom G Richardson

    Published 2023-01-01
    “…We also investigated whether putative mediators may play a role in findings for traits previously implicated in PrCa risk (i.e., lipoprotein a (Lp(a)), body mass index (BMI), and testosterone). …”
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  20. 64560

    NRF1-Induced lncRNA DDX11-AS1 Contributes to the Progression of Hepatocellular Carcinoma via Activating CA9 Expression and the MEK/ERK Pathway by Li Y, Shi M, Bie B, Tian H, Li J, Li Z, Sun J

    Published 2025-05-01
    “…Nevertheless, the exact biological functions and fundamental molecular processes of DDX11-AS1 in HCC require further in-depth investigation.Methods: A comprehensive bioinformatics analysis was carried out to explore the expression of DDX11-AS1 and its clinical implication in HCC utilizing the TCGA data. qRT-PCR was employed to validate the expression of DDX11-AS1 in HCC tissues/cell lines. …”
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