Bacteria‐Mediated Tumor‐Targeting Delivery of Multienzyme‐Mimicking Covalent Organic Frameworks Promoting Pyroptosis for Combinatorial Sono‐Catalytic Immunotherapy by Yunyun Liu, Lihua Xiang, Yitong Li, Shen Zhang, Ying Zhang, Hui Shi, Hui Liu, Dou Du, Bangguo Zhou, Beibei Ye, Shaoyue Li, Haohao Yin, Huixiong Xu, Yifeng Zhang

“…Moreover, PEG‐CuP‐COF showed outstanding glutathione peroxidase‐mimicking activities, impairing the antioxidant defense in tumor cells and enhancing sonodynamic efficiency by making them more vulnerable to ROS‐induced damage. …”
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Qing Hua Chang Yin ameliorates chronic colitis in mice by inhibiting PERK–ATF4–CHOP pathway of ER stress and the NF-κB signalling pathway by Liya Liu, Youqin Chen, Yuying Han, Xinran Zhang, Yulun Wu, Jing Lin, Liujing Cao, Meizhu Wu, Huifang Zheng, Yi Fang, Lihui Wei, Thomas J. Sferra, Anjum Jafri, Xiao Ke, Jun Peng, Aling Shen

“…Compared with the DSS group, QHCY significantly improved symptoms of chronic colitis like DAI increase, weight loss, colon shortening and histological damage. It notably reduced serum levels of IL-6, IL-1β and TNF-α. …”
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Aqueous extract of Solanum americanum Mill. relieves functional constipation by modulating the enteric nervous system and gut micro-ecosystems by Xiaoyu Gao, Xiaoyu Gao, Xiaoyu Gao, Yanan Li, Yifan Hu, Yifan Hu, Weixing Yang, Lei Peng, Jun Sheng, Yang Tian, Lu Yao, Yan Zhao

“…Notably, SAAE alleviated loperamide-induced gut inflammation, damaged gut barrier, and gut microbiota disruption. …”
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Exploring novel roles of lipid droplets and lipid metabolism in regulating inflammation and blood–brain barrier function in neurological diseases by Luo Fu, Luo Fu, Ting Luo, Ting Luo, Zhongnan Hao, Yongli Pan, Yongli Pan, Wenqiang Xin, Lin Zhang, Lin Zhang, Zhuhong Lai, Haitao Zhang, Hua Liu, Wei Wei, Wei Wei

“…Surface modifications of liposomes can further enhance their targeting efficiency, enabling them to selectively bind to specific brain cell types, including neurons, astrocytes, and microglia. …”
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Double effects of mitigating cyanobacterial blooms using modified clay technology: regulation and optimization of the microbial community structure by Jianan Zhu, Jianan Zhu, Zhiming Yu, Zhiming Yu, Zhiming Yu, Xihua Cao, Xihua Cao, Xihua Cao, Wenbin Jiang, Wenbin Jiang, Liyan He, Liyan He, Xiaomiao Zang, Xiaomiao Zang, Xiuxian Song, Xiuxian Song, Xiuxian Song

“…Results revealed that the dominant bloom species were Microcystis, and an 87.68–97.01% removal efficiency of whole algal biomass was achieved after 3 h of MC treatment. …”
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Numerical Evaluation of the Effectiveness of the Use of Endplates in Front Wings in Formula One Cars under Multiple Track Operating Conditions by Aldo Saul Laguna-Canales, Guillermo Urriolagoitia-Sosa, Beatriz Romero-Ángeles, Miguel Martinez-Mondragon, Miguel Angel García-Laguna, Reyner Iván Yparrea-Arreola, Jonatan Mireles-Hernández, Francisco Carrasco-Hernández, Alejandro Urriolagoitia-Luna, Guillermo Manuel Urriolagoitia-Calderón

“…The last change in the technical regulations of Formula One that came into force in 2022 brought with it significant changes in the aerodynamics of the vehicle; among these, those made to the front wing stand out since the wing was changed to a more straightforward shape with fewer parts but with no less efficiency. The reduction in its components suggests that if one part were to suffer damage or break down, the efficiency of the entire front wing would be affected; however, from 2022 to date, there have been occasions in which the cars have continued running on the track despite losing some of the endplates. …”
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Influence of the pH Synthesis of Fe₃O₄ Magnetic Nanoparticles on Their Applicability for Magnetic Hyperthermia: An In Vitro Analysis by Bárbara Costa, Eurico Pereira, Vital C. Ferreira-Filho, Ana Salomé Pires, Laura C. J. Pereira, Paula I. P. Soares, Maria Filomena Botelho, Fernando Mendes, Manuel P. F. Graça, Sílvia Soreto Teixeira

“…<b>Conclusions</b>: It was found that the pH of the reaction can influence the size, morphology, magnetization, and thermal efficiency of the MNP. The MNP with the highest composition of Fe₃O₄ was synthesized with a pH of 12.75, with a cubic morphology and a SAR value of 92.7 ± 3.2 W/g.…”
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Flowers and Leaves of <i>Artemisia absinthium</i> and <i>Artemisia annua</i> Phytochemical Characterization, Anti-Inflammatory, Antioxidant, and Anti-Proliferative Activities Evalu... by Mădălina Țicolea, Raluca Maria Pop, Marcel Pârvu, Lia-Oxana Usatiuc, Ana Uifălean, Dalina Diana Pop, Eva Fischer-Fodor, Floricuța Ranga, Crina Claudia Rusu, Adriana Florinela Cătoi, Francisco Palma-Garcia, Luciana-Mădălina Gherman, Alina Elena Pârvu

“…The tested plant extracts had significant and dose-dependent in vivo anti-inflammatory and antioxidant activity, with the <i>A. annua</i> flowers extract having the lowest efficiency. The anti-inflammatory and antioxidant activity biomarkers correlated with the extracts’ chemical composition. …”
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γ-Aminobutyric Acid Alleviates Salinity-Induced Impairments in Rice Plants by Improving Photosynthesis and Upregulating Osmoprotectants and Antioxidants by Jiaxin Feng, Tianyang Zhou, Yibiao Gu, Chenchen Shu, Kuanyu Zhu, Weiyang Zhang, Hao Zhang, Lijun Liu, Zhiqin Wang, Junfei Gu, Jianchang Yang

“…These combined effects help maintain photosynthetic efficiency and support overall plant growth under salt-stressed environments. …”
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<i>Salmonella</i> Typhi-Exposed Placentae: Chorionic Villi Histomorphology and Neonatal Birthweight by Patience B. Tetteh-Quarcoo, Joana Twasam, Kevin Kofi Adutwum-Ofosu, John Ahenkorah, Bismarck Afedo Hottor, Nicholas T. K. D. Dayie, Peter Ofori Appiah, Emmanuel Afutu, Fleischer C. N. Kotey, Emilia Asuquo Udofia, Nii Koney-Kwaku Koney, Benjamin Arko-Boham, Eric S. Donkor

“…Although birthweight may appear unaffected, the observed changes point to reduced placental efficiency and merit further research into their developmental consequences and long-term effects on babies.…”
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Nanotechnology-based herbal medicine: Preparation, synthesis, and applications in food and medicine by Farhang H. Awlqadr, Kithar Rasheed Majeed, Ammar B. Altemimi, Arkan Mohammed Hassan, Syamand Ahmed Qadir, Mohammed N. Saeed, Aryan Mahmood Faraj, Tablo H. Salih, Alaa Jabbar Abd Al‐Manhel, Mazin A.A. Najm, Efstathia Tsakali, Jan F.M. Van Impe, Ahmed A. Abd El-Maksoud, Tarek Gamal Abedelmaksoud

“…Nonetheless, nanotechnology has found its way into these chemical compositions, bringing about the issues of scaling up, cost-efficiency, regulatory compliance, and safety concerns. …”
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Reproductive Success of <i>Trichogramma ostriniae</i> over <i>Trichogramma dendrolimi</i> in Multi-Generational Rearing on Corn Borer Eggs by Yu Wang, Asim Iqbal, Kanwer Shahzad Ahmed, Yuan-Yuan Zhou, Chen Zhang

“…The <i>Trichogramma dendrolimi</i> Matsumura and <i>T. ostriniae</i> Pang and Chen are the most efficient biocontrol agents for controlling ACB among the available <i>Trichogramma</i> species. …”
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Veterinary Perspectives on Hemoglobin-Based Oxygen Carriers in Experimental Hemorrhagic Shock: Insights from Rabbit Models by Ștefania-Mădălina Dandea, Alina-Diana Hașaș, Vlad-Alexandru Toma, Maria Lehene, Florina Scurtu, Cosmin Petru Peștean, Răzvan-Andrei Codea, Lucia-Victoria Bel, Iulia Melega, Radu Silaghi-Dumitrescu, Bogdan Sevastre

“…As previously described, HBOCs based on ovine hemoglobin display better efficiency in the context of hemorrhagic shock compared to those based on the more commonly used bovine hemoglobin. …”
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The protective effects of FeOx/NC nanozymes on chondrocytes by scavenging reactive oxygen species by Jianfeng GUO, Rongwei ZHANG, Zhangrui HUANG, Zhiquan PANG, Shixing LUO

“…Macroscopic and histological evaluations demonstrated that FeOx/NC treatment alleviated cartilage damage compared with the saline group. Conclusion FeOx/NC nanozymes exhibit excellent biocompatibility and possess multi-enzyme catalytic activity, enabling them to efficiently scavenge intracellular ROS in chondrocytes, thereby suppressing oxidative stress and alleviating the progression of OA.…”
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Melatonin Alleviates Photosynthetic Injury in Tomato Seedlings Subjected to Salt Stress via OJIP Chlorophyll Fluorescence Kinetics by Xianjun Chen, Xiaofeng Liu, Yundan Cong, Yao Jiang, Jianwei Zhang, Qin Yang, Huiying Liu

“…Conversely, the injection of exogenous p-CPA exacerbated salt stress-related damage to the photosystem of tomato seedlings and diminished the beneficial effects of MT. …”
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Press Forward: Advancing Vaccine Production With High Hydrostatic Pressure Inactivation for Global Health Equity by Miss Martina Brandolini, Dr Alessandra Mistral De Pascali, Mr Giorgio Dirani, Mr Massimiliano Guerra, Ms Silvia Zannoli, Prof Pietro Rocculi, Dr Michele Morbarigazzi, Dr Davide Lelli, Dr Antonio Lavazza, Dr Francesca Battioni, Prof Monica Cricca, Prof Alessandra Scagliarini, Prof Vittorio Sambri

“…Discussion: Preliminary results show HHP efficacy in producing viral inactivates that can efficiently be used as immunogens in murine animal models. …”
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Synergistic effects of foliar applied glycine betaine and proline in enhancing rice yield and stress resilience under salinity conditions by Sobhi F. Lamlom, Aly A. A. El-Banna, Honglei Ren, Bassant A. M. El-Yamany, Ehab A. A. Salama, Gawhara A. El-Sorady, Mohamed M. Kamara, Amal Mohamed AlGarawi, Ashraf Atef Hatamleh, Abdelsalam A. Shehab, Ahmed M. Abdelghany

“…With the increasing salinization of agricultural lands, finding effective agronomic practices and treatments to mitigate salt-induced damage in rice crops is critical for ensuring food security. …”
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Comparative pharmacodynamics of intranasal and enteral administration of captopril for uncomplicated hypertensive crises by I. L. Kechyn, V. V. Hladyshev, I. О. Pukhalska

“…Uncomplicated hypertensive crises without acute or progressive damage to the target organs pose a potential threat to the patient’s life and require rapid reduction of arterial pressure within hours or days in an outpatient setting. …”
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The Acute Effects of Cannabidiol on Physiological and Subjective Responses to Endurance Exercise: A Dose-Ranging Randomised Controlled Crossover Trial by Ayshe Sahinovic, Namson S. Lau, Angelo Sabag, Rebecca Gordon, Amanda J. Cox, Katie Walker, Christopher Irwin, Ben Desbrow, Nathan Johnson, Paul J. Austin, Paul Haber, Iain S. McGregor, Danielle McCartney

“…CBD also had a limited effect on exercise physiology and performance, with heart rate, exercise efficiency (i.e., $${\dot{\text{V}}}$$ V ˙ O2), $${\dot{\text{V}}}$$ V ˙ O2peak and time to exhaustion (TTE) unchanged relative to placebo (p’s > 0.05). …”
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ELABELA promotes the migration and homing of bone marrow mesenchymal stem cells to myocardial injury sites through the ERK1/2/miR-299a-5p/Exo70 pathway by Jing-Yu Hou, Hao Wu, Shuang-Mei Li, Xiao-Jing Li, Shu-Jun Yang, Xu-Xiang Chen, Chang-Qing Zhou, Hui-Bao Long, Hai-Dong Wu, Jia-Ying Fu, Ya-Jie Guo, Tong Wang

“…BackgroundBone marrow mesenchymal stem cells (BMSCs) hold promise for repairing myocardial injury following acute myocardial infarction (AMI), but their clinical application is hindered by poor migration, homing efficiency, and survival rates. Previously, we demonstrated that ELABELA (ELA), a small peptide, enhances the survival of rat BMSCs under hypoxia-reoxygenation (H/R) conditions by activating ERK1/2. …”
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