Intraperitoneal injection but not oral administration of ellagic acid: a novel immunomodulator via targeting casein kinase 2 signaling pathway by Wenhui Qi, Bing Han, Tingting Cui, Peixin Shen, Zhuohua Zhao, Yaping Yan, Libin Wang, Xinyu Lu, Yuan Zhang, Xing Li

“…In addition, intraperitoneal EA also ameliorated the brain damage in a neuromyelitis optica (NMO) model, and significantly prevented the immune rejection of allograft skin graft. …”
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Enhancing neurological disease diagnostics: fusion of deep transfer learning with optimization algorithm for acute brain stroke prediction using facial images by Fadwa Alrowais, Mohammed Alqahtani, Jahangir Khan, Achraf Ben Miled, Da’ad Albalawneh, Abdulwhab Alkharashi, Samah Al Zanin, Radwa Marzouk

“…Furthermore, fusion models such as Inception-V3 and EfficientNet-B0 perform the feature extraction. Moreover, the hybrid of convolutional neural network and bidirectional long short-term memory (CNN-BiLSTM) model is employed for the brain stroke classification process. …”
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Radiopharmaceuticals and their applications in medicine by Siqi Zhang, Xingkai Wang, Xin Gao, Xueyao Chen, Linger Li, Guoqing Li, Can Liu, Yuan Miao, Rui Wang, Kuan Hu

“…Radiopharmaceutical therapy, which directly causes systematic and irreparable damage to targeted cells, has attracted increasing attention in the treatment of refractory diseases that are not sensitive to current therapies. …”
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CD44-targeted virus-mimicking nanomedicine eliminates cancer stem cells and mitigates chemoresistance in head and neck squamous cell carcinoma by Yiwen Chen, Zhen Qin, Yujia Wang, Baoxin Gu, Jing Wang, Yunfei Zheng, Yuting Niu, Lingfei Jia

“…The rough surface of VNP-HA provided better drug delivery efficiency than smooth nanoparticles modified with HA. …”
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Phytochemical composition and biological activities of extracts from Astragalus membranaceus arieal parts by Mohamed El Amine Smaali, Fadila Khaldi, Maya Bouafia, Fatima Kerroum, Mohamed Abidi, Mohamed Lahmadi, Nassim Madi, Barbara Sawicka, Sheikh F. Ahmad, Sabry M. Attia, Wafa Zahnit, Mohammed Messaoudi

“…The extracts had a strong protective effect of Fenton-induced DNA damage. The XTT test revealed that the extracts had weaker cytotoxicity profile against EMT6 cell line. …”
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Development and application of a curcumin-cinnamon essential oil nanoemulsion agent against mycobacteria by Zhihui Lei, Zhihui Lei, Zhihui Lei, Yixuan Ren, Jinyao Wang, Haisu Shi, Hu Lin, Hong Chen, Lijun Bi, Lijun Bi, Yutang Wang, Hongtai Zhang, Hongtai Zhang, Hongtai Zhang

“…The nanoemulsion demonstrated high encapsulation efficiency (90.2%) and stability, with a stability coefficient of 0.984. …”
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Variability of Material Solutions for the Perimeter Walls of Buildings in Post-Industrial Settlements as Part of Energy Rehabilitation and Achieving Carbon Neutrality by Hamed Afsoosbiria, Darja Kubečková, Oskar Kambole Musenda, Khaled Mohamed

“…Overall, the findings underscore the importance of advanced materials in achieving efficient thermal performance while balancing architectural and structural demands. …”
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Percutaneous cryoablation in soft tissue tumor management: an educational review by Sylvain Bodard, Ruben Geevarghese, Leo Razakamanantsoa, Julien Frandon, Elena N. Petre, Clement Marcelin, François H. Cornelis

“…PCA functions by freezing tissue, which induces ice crystal formation and cell death without damaging collagen structures. Technical considerations include the selection and handling of cryoprobes and cryogenic agents, procedural duration, and choice of image guidance for precision. …”
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Adaptation of Grain Cleaning Equipment for Kalonji and Sesame Seeds by Ramadas Narayanan, Vu Hoan Tram, Tieneke Trotter, Charissa Rixon, Gowrishankaran Raveendran, Federico Umansky, Surya P. Bhattarai

“…Threshing and cleaning are crucial for efficient harvest procedures that are carried out to separate the grains from the biomass and eliminate any potential contaminants or foreign debris. …”
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Evaluating environmental impacts of thorium extraction: A comparative study of solvent and electrosorption technologies using life cycle assessment (LCA) by Naseem Akhtar, Aznan Fazli Ismail, Marlia Mohd Hanafiah, Syazwani Mohd Fadzil, Sulgiye Park

“…Our study shows that electrosorption from WLP demonstrates superior environmental sustainability compared with solvent extraction from monazite, positioning it a more viable and efficient approach for radioactive waste treatment.…”
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A combined model of shoot phosphorus uptake based on sparse data and active learning algorithm by Tianli Wang, Yi Zhang, Haiyan Liu, Fei Li, Dayong Guo, Ning Cao, Yubin Zhang

“…The soil ecosystem has been severely damaged because of the increasingly severe environmental problems caused by excessive application of phosphorus (P) fertilizer, which seriously hinders soil fertility restoration and sustainable farmland development. …”
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In Vitro Antimicrobial Efficacy Assessment of Ethanolic, Aqueous, and Dual Solvent Extracts of Mushroom <i>Ganoderma lucidum</i>: Genomic and Morphological Analysis by Ewunkem Akamu, Lydia Merrills, Zahirah Williams, Brittany Justice, Uchenna Iloghalu, Vera Williams, Dinesh Singh

“…Mushrooms seem to be a promising, and possibly more efficient, alternative method to that of conventional antimicrobials. …”
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Experimental investigation and predictive modelling of CO2 laser processing of wood-plastic composites (WPCs) by Sharizal Ahmad Sobri, Teoh Ping Chow, Tan Koon Tatt, Mohd Hisham Nordin, Andi Hermawan, Mohd Natashah Norizan

“…This study provides essential guidance for optimizing laser machining of WPCs, promoting precision, reduced thermal damage, and sustainable manufacturing practices.…”
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Versatile enhancement of the killing potential of anti-cancer agents achieved by peptide mimetics of the PCNA interface towards specialized DNA polymerases by Yiovana Verónica Okraine, María Belén de la Vega, Sofía Venerus Arbilla, Ginette Moyano, Agostina P. Bertolin, Horacio M. Pallarés, Lisa Wiesmüller, Sabrina F. Mansilla, Vanesa Gottifredi

“…Abstract Cancer cells that survive chemotherapy achieve full DNA duplication despite the accumulation of damaged DNA triggered by chemotherapy. This happens because the synthesis of DNA at damaged sites is granted by tolerance events including translesion DNA synthesis (TLS), a process that promotes the use of specialized DNA polymerases (S-Pols) for DNA synthesis. …”
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Effect of dietary quercetin supplementation on high-starch diet-induced growth impairment, metabolic dysregulation, and oxidative stress in largemouth bass (Micropterus salmoides) by Yexin Wei, Xin Liu, Jia Huang, Haijie Chen, Yuanfa He, Yongjun Chen, Shimei Lin

“…Compared with the LS group, the HS group exhibited significant growth inhibition and liver damage. Notably, quercetin supplementation significantly improved weight gain (WG), specific growth rate (SGR), and protein efficiency ratios (PER); reduced blood glucose, serum triglycerides (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and liver enzyme activities (AST and ALT). …”
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Enhancing crop resilience to water stress through iron nanoparticles: A critical review of applications and implications by Tajwar Alam, Sanaullah Jalil, Ghulam Jilani, Arshad Nawaz Chaudhry, Zia Ul-Haq, Iram Naz, Muhammad Abbas Khan, Xinghong Yang, Marian Brestic, Milan Skalicky, Ayman El Sabagh

“…Particularly, Fe-NPs improve water use efficiency (WUE) and root development, facilitating water and nutrient uptake under stress conditions. …”
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Stereotactic Radiosurgery in the Complex Treatment of Patients With Epilepsy Associated With Various Structural Brain Lesions by V. V. Krylov, V. A. Rak, A. S. Tokarev, M. V. Sinkin, I. S. Trifonov, O. L. Yevdokimova, V. N. Stepanov, E. N. Rozhnova, G. V. Koinash

“…BACKGROUND Structural damage to the brain substance in adults is one of the most common causes of epilepsy. …”
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Research and Performance Evaluation of Environmentally Friendly Shale Inhibitor TIL-NH₂ for Shale Gas Horizontal Wells by Yuexin Tian, Xiangjun Liu, Yintao Liu, Haifeng Dong, Guodong Zhang, Biao Su, Xiaofeng Liu, Yifan Hu, Jinjun Huang, Zeze Lu

“…This research provides a high-efficiency and environmentally friendly new inhibitor for green drilling fluid systems in horizontal shale gas wells, offering important references for technological advancements in unconventional energy development.…”
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MIF tautomerase inhibitor TE-11 prevents inflammatory macrophage activation and glycolytic reprogramming while reducing leukocyte migration and improving Crohn’s disease-like colit... by Eszter Vámos, Viola Bagóné Vántus, Péter Deák, Nikoletta Kálmán, Eva Maria Sturm, Barsha Baisakhi Nayak, Lilla Makszin, Tamás Loránd, Ferenc Jr Gallyas, Balázs Radnai

“…We performed qPCR, ROS and nitrite determinations, ELISA measurements, mitochondrial oxygen consumption rate and extracellular acidification rate determinations.ResultsTE-11 improved mucosal damage, reduced inflammation score and concentration of IL-1β and IL-6 in the colon. …”
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Numerical simulation optimization analysis and field test for large deformation control of soft rock in Tabaiyi Tunnel by Jieli LI, Jiaguo ZHANG, Quansheng CHEN, Rui AO, Jihao SUN, Pengxiao GUAN

“…Under the original support, there were large deformation of the initial support, deformation of the steel arch frame, and sudden mud and water influx. The deformation and damage mechanism of the surrounding rock was studied by field investigation, rock structure analysis and numerical simulation. …”
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