THE ROLE OF PLASMA ENRICHED WITH PLATELETS AND GROWTH FACTORS IN MODERN MEDICAL PRACTICE by O.V. Pavlenko, R.Yu. Bida

“…It is a technology developed to promote the regeneration, repair and healing of the injured and damaged tissues. In the article below, we have elaborated the methods of PRGF-Endoret application to patients suffering from injuries or damages to soft tissue in the maxillofacial area. …”
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Integrative application of licorice root extract and melatonin improves faba bean growth and production in Cd-contaminated saline soil by Shimaa A. Abd El Mageed, Ali A. S. Sayed, Ahmed Shaaban, Khaulood A. Hemida, Abdelsattar Abdelkhalik, Wael M. Semida, Ibrahim A. A. Mohamed, Mohammed A. H. Gyushi, Yasmine H. Abd Elmohsen, Taia A. Abd El Mageed

“…Results Cadmium (Cd) and salinity-induced stress significantly altered leaf integrity, photosynthetic efficiency, total soluble sugars (TSS), free proline (FPro), total phenolic, DPPH, and total soluble proteins (TSP), non-enzymatic and enzymatic antioxidants, growth characteristics and yield-related traits. …”
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SRT3025-loaded cell membrane hybrid liposomes (3025@ML) enhanced anti-tumor activity of Oxaliplatin via inhibiting pyruvate kinase M2 and fatty acid synthase by Xiaobin Wang, Shulin Li, Zichen Li, Zhuona Lin, Zhifeng Wang

“…Drug encapsulation efficiency and loading capacity were determined to investigate the advantages of the SRT3025-loaded cell membrane hybrid liposomes (3025@ML). …”
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Dietary protein re-alimentation following restriction improves protein deposition via changing amino acid metabolism and transcriptional profiling of muscle tissue in growing beef... by Jiaqi Wang, Chun Shen, Guangyong Zhao, Mark D. Hanigan, Mengmeng Li

“…Compared to the CON, REC reduced retained N (P < 0.05), and protein re-alimentation increased retained N and N utilization efficiency (P < 0.05), due to reduced urinary urea, hippuric acid, and creatinine excretions (P < 0.05). …”
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Comparison of wind farm control strategies under realistic offshore wind conditions: turbine quantities of interest by J. A. Frederik, E. Simley, K. A. Brown, G. R. Yalla, L. C. Cheung, P. A. Fleming

“…<p>Wind farm flow control is a strategy to increase the efficiency and therefore lower the levelized cost of energy of a wind farm. …”
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Preparation, characterization and application of polymeric ultra-permeable biodegradable ferromagnetic nanocomposite adsorbent for removal of Cr(VI) from synthetic wastewater: kine... by Evans Suter, Hilary Rutto, Robert Makomere, Musamba Banza, Tumisang Seodigeng, Sammy Kiambi, Wesley Omwoyo

“…Cr(VI) concentrations exceeding a few parts per billion (ppb) can cause serious health problems such as asthma, blood cancer, kidney-related diseases, liver and spleen damage, as well as neurological system, immunological deficiencies, and reproductive issues. …”
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RESULTS OF AN OBSERVATIONAL PROSPECTIVE STUDY OF THE EFFICACY AND SAFETY OF BELIMUMAB (BENLYSTA®) IN SYSTEMIC LUPUS ERYTHEMATOSUS IN REAL CLINICAL PRACTICE by E. A. Aseeva, S. K. Soloviev, A. A. Mesnyankina, T. M. Reshetnyak, N. E. Lopatina, S. I. Glukhova, E. L. Nasonov

“…BLM was used as monthly intravenous infusions at a dose of 10 mg/kg. The efficiency and safety of the therapy were evaluated monthly and 1 year after the initiation of treatment with BLM; SLE activity was estimated using SLEDAI-2K; a physician’s global assessment of disease activity on a visual analogue scale (VAS); anti-DNA antibody level changes, complement levels, a GC dose, damage index, and adverse events were determined.Results and discussion. …”
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Effects of High Temperature Stress on Leaf Chlorophyll Fluorescence Characteristics of Kiwifruit by Li Hualong, Wang Jinghong, Zhang Weimin, Bai Qinfeng, Zhang Tao, Pan Yuying, Quan Wenting

“…The high temperature damage of kiwifruit is particularly prominent, such as leaf wilting, shedding, fruit sunburn, fruit drop, and even tree death.In order to explore the effects of high temperature stress on photosynthetic apparatus of kiwifruit leaves and establish a heat injury identification index based on chlorophyll fluorescence response, the variation characteristics of the FO(minimal recorded fluorescence intensity), Fm(maximal recorded fluorescence intensity), Fa(maximal photochemistry efficiency), ΔWK(relative variable fluorescence difference at 300 μs), Tr(trapped energy flux per area at t=0), Et(electron transport flux per area at t=0), Dd(dissipated energy flux per area at t=0), Rm (density of QA-reducing PSⅡ reaction centers) in kiwifruit leaves under 30 ℃, 33 ℃, 36 ℃, 39 ℃, 42 ℃, 45 ℃, 48 ℃, 50 ℃, 52 ℃, 54 ℃ condition are studied by using the technique of fast chlorophyll fluorescence induction dynamics analysis(JIP-test). …”
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Development and Test of Pomelo Fruit Inventory Grading Management System Based on RFID Technology by Haijun QI, Jintao ZHANG, Bofeng ZENG, Yizhi LUO, Xingxing ZHOU

“…【Objective】Aiming at the problems of easy damage of bulk stacking, difficulty in inventory grading management, and low degree of digitization in inventory management of pomelo processing and circulation enterprises, a digital management system for pomelo inventory grading was proposed.…”
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Phenomenon of suppression of estrogen signaling in breast cancer cells under ultraviolet irradiation: role of Snail proteins by D. V. Sorokin, O.  E. Andreeva, A. M. Scherbakov, D. I. Salnikova, M. V. Gudkova, M. A. Krasil’nikov

“…The study of the effect of irradiation or any other DNA-damaging agents on the sensitivity of tumors to conservative therapy, drug or hormonal, is among the most imporant tasks that determine the efficiency of combined therapy of cancer patients.Aim. …”
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Novel Hypericin-loaded nanoparticles as a new drug delivery system ameliorate olanzapine-induced early renal injury and oxidative stress: In vitro and in vivo approaches by Abeer M. Abd El-Hameed, Fatimah A.R. AbdulAlim, Amal H. Alsehli, Fadwa A. Elroby

“…An entrapment efficiency of around 95.61 ± 0.28 %, and a prolonged release of less than 20 % after 12 h were validated by the current results. …”
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Development and Application of an In Vitro Drug Screening Assay for <i>Schistosoma mansoni</i> Schistosomula Using YOLOv5 by María Alejandra Villamizar-Monsalve, Javier Sánchez-Montejo, Julio López-Abán, Belén Vicente, Miguel Marín, Noelia Fernández-Ceballos, Rafael Peláez, Antonio Muro

“…Conclusions: This AI-powered method significantly improves accuracy and time efficiency compared to traditional microscopy. It enables the evaluation of compounds for potential schistosomiasis drugs without the need for dyes or specialized equipment, facilitating more efficient drug assessment.…”
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Fiber reinforced ceramic matrix composites: from the controlled fabrication to precision machining by Shuoshuo Qu, Yuying Yang, Peng Yao, Luyao Li, Yang Sun, Dongkai Chu

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Analysis of Whole-Genome for <i>Alternaria</i> Species Identification by Ying Yang, Yutong Gan, Wenjie Xu, Yuanhao Huang, Tianyi Xin, Rui Tan, Jingyuan Song

“…Therefore, AGE proves to be a highly robust and efficient method for the detection of <i>Alternaria</i> species, offering broad potential for various applications.…”
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METTL16 is Required for Meiotic Sex Chromosome Inactivation and DSB Formation and Recombination during Male Meiosis by Lisha Yin, Nan Jiang, Wenjing Xiong, Shiyu Yang, Jin Zhang, Mengneng Xiong, Kuan Liu, Yuting Zhang, Xinxin Xiong, Yiqian Gui, Huihui Gao, Tao Li, Yi Li, Xiaoli Wang, Youzhi Zhang, Fengli Wang, Shuiqiao Yuan

“…Collectively, this study identified METTL16 as a key regulator of male meiosis and demonstrated that it modulates meiosis by interacting with MSCI‐related factors and regulating m6A levels and translational efficiency (TE) of meiosis‐related genes.…”
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Proteostasis Decline and Redox Imbalance in Age-Related Diseases: The Therapeutic Potential of NRF2 by Brigitta Buttari, Antonella Tramutola, Ana I. Rojo, Niki Chondrogianni, Sarmistha Saha, Alessandra Berry, Letizia Giona, Joana P. Miranda, Elisabetta Profumo, Sergio Davinelli, Andreas Daiber, Antonio Cuadrado, Fabio Di Domenico

“…By inducing NRF2, it is possible to mitigate the damaging effects of oxidative stress, metabolic dysfunction, and inflammation, thus reducing protein misfolding. …”
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Effects of the replacement of fishmeal with defatted black soldier fly (Hermetia illucens) larvae meal in high lipid diets on growth, serum liver antioxidant and disease resistance... by Weibin Huang, Wanting Huang, Wenshan Cai, Hao Liu, Menglong Zhou, Beiping Tan, Hengyang Song, Xiaohui Dong

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Application of Microsponge Drug Platform to Enhance Methotrexate Administration in Rheumatoid Arthritis Therapy by Noemi Fiaschini, Patrizia Nadia Hanieh, Daniela Ariaudo, Rita Cimino, Carlo Abbate, Elena Romano, Francesca Cavalieri, Mariano Venanzi, Valeria Palumbo, Manuel Scimeca, Roberta Bernardini, Maurizio Mattei, Alberto Migliore, Antonio Rinaldi

“…Results: A highly stable and rounded-shaped micrometric MSP, characterized by an open porosity inner structure, achieved both a high MTX loading efficiency and a slow release of MTX after injection. …”
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Application of mesenchymal stem cells in liver fibrosis and regeneration by Zhenyu Liu, Junkai Ren, Cheng Qiu, Ying Wang, Tong Zhang

“…MSCs are crucial in reversing liver fibrosis and repairing liver damage through the secretion of growth factors, regulation of signaling pathways, and modulation of immune responses. …”
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Size effect-based improved antioxidant activity of selenium nanoparticles regulating Anti-PI3K-mTOR and Ras-MEK pathways for treating spinal cord injury to avoid hormone shock-indu... by Peixin Liu, Xiaodong Liu, Zihao Wu, Kui Shen, Zhaofeng Li, Xiaowei Li, Qifeng Wu, Leung Chan, Zhong Zhang, Yutong Wu, Liwen Liu, Tianfeng Chen, Yi Qin

“…In vivo studies indicated that LNT-UsSeNPs efficiently penetrated the BSCB and effectively inhibited the apoptosis of spinal neurons. …”
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