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2961
2-Deoxy-D-Glucose and ES-936 sensitize cancer- but not normal cells to both low- and high LET irradiation
Published 2025-08-01“…The utilization of glycolysis even under aerobic conditions in cancer cells presents a unique target to deprive cancer cells of energy and metabolites required not only for their rapid cell growth but also for the repair of irradiation induced DNA damage. Furthermore, cancer cells have been observed to exhibit elevated levels of reactive oxygen species and potentially react more sensitively to an induced disturbance of the redox balance, especially after irradiation mediated oxidative stress. …”
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2962
Storm Surge Risk Assessment Based on LULC Identification Utilizing Deep Learning Method and Multi-Source Data Fusion: A Case Study of Huizhou City
Published 2025-02-01“…Among the frequent natural disasters, there is a growing concern that storm surges may cause enhanced damage to coastal regions due to the increase in climate extremes. …”
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2963
Employing Neural Networks, Fuzzy Logic, and Weibull Analysis for the Evaluation of Recycled Brick Powder in Concrete Compositions
Published 2024-12-01“…Additionally, an impact damage evolution equation was presented for mixtures containing RBP. …”
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2964
Liposome-encapsulated antibiotics and biosurfactants: an effective strategy to boost biofilm eradication in cooling towers
Published 2025-06-01“…Liposomes were produced with initial diameters of 100 and 200 nm, and encapsulation efficiencies were 56.7% for rhamnolipid, 47.3% for meropenem, and 31.25% for chloramphenicol. …”
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2965
Rock and machine interaction law during TBM crossing fault and prevention and control technology of jamming disaster in Shoushan No.1 Mine
Published 2025-08-01“…These problems not only affect the efficiency of TBM excavation, but also pose a serious threat to its structural stability, which eventually leads to the occurrence of jamming disaster. …”
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2966
Mechanism of MCP-1 in Acute Lung Injury and Advanced Therapy by Drug-Loaded Dextrin Nanoparticle
Published 2018-01-01“…Because of the high transfection efficiency of inhibitor RS102895packgaed by polyaldehyde dextran nanoparticles, this phenomenon particularly reached a significant level. …”
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2967
Naphthalimide-polyamine conjugates: a promising avenue for targeted anticancer therapy
Published 2025-12-01Get full text
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2968
The Effects of New Selective PPARα Agonist CP775146 on Systematic Lipid Metabolism in Obese Mice and Its Potential Mechanism
Published 2020-01-01“…Conclusion. CP775146 efficiently alleviates obesity-induced liver damage, prevents lipid accumulation by activating the liver fatty acid β-oxidation pathway, and regulates the expression of genes that control brown fat-like pathway in eWAT.…”
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2969
Longitudinal Changes of Serum Creatine Kinase and Acute Kidney Injury among Patients with Severe COVID-19
Published 2022-01-01“…Several etiologies have been identified, including pigment deposition likely associated with myopathic damage. Nevertheless, the relationship between longitudinal creatine-kinase trends and renal outcomes is uncertain. …”
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2970
The Effect of Cirata Reservoir Sediment on Early Developmental Stage of Common Carp (Cyprinus carpio) Embryo
Published 2009-07-01“…The damage of eggs and larval morphologies in treatments with sediment supernatant was likely caused by the presence Pb and organic matters which act in synergy. …”
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2971
Osteoplastic biomaterials from organic and mineral components of the bone matrix: a literature review
Published 2024-11-01“…The use of biomaterials created using biomimetics principles increases the efficiency of bone tissue damage restoration.…”
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2972
Construction and Influence of Induced Pluripotent Stem Cells on Early Embryo Development in Black Bone Sheep
Published 2025-04-01“…The piggyBac+TET-on transposon induction system has a high efficiency in integrating exogenous genes in multiple cell types, can precisely integrate to reduce genomic damage, has a flexible gene expression regulation, and a strong genetic stability. …”
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2973
Comparison of enzymatic and bisulfite conversion of circulating cell-free tumor DNA for DNA methylation analyses
Published 2025-06-01“…The cytosine conversion efficiency was 99–100% for both enzymatic and bisulfite conversion. …”
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2974
Optimization of the Lens Nucleus Fragmentation during Phacoemulsification in Patients with Pseudoexfoliation Syndrome
Published 2018-10-01“…The proposed technology is gentle crushing of the lens nucleus in patients with PES, you can reduce the pressure on the fibers of the zonule, the probability of damage to the ligaments and posterior capsule of the lens based on the use of phacofragmentation original design. …”
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2975
Fibroblast IRF7-mediated chondrocyte apoptosis affects the progression of collapse in steroid-induced osteonecrosis of the femoral head
Published 2025-03-01“…HE was used to compare the characteristics of synovial tissue damage, and immunofluorescence and immunohistochemistry were used to compare the expression levels of VIM, IRF7, and IFNα. …”
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2976
Potential of Bacillus subtilis PB6 in corn-based diets to combat subclinical necrotic enteritis in broilers
Published 2025-10-01“…In conclusion, Pb improves feed efficiency and mitigates the adverse effects of SNE-induced damage to intestinal health, while Xy enhances pre-challenge growth without augmenting Pb’s benefits during NE.…”
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2977
LOW AND MEAN RADIATION DOSES IMPACT ON THE CEREBRAL TRACTS STRUCTURE OF THE CHERNOBYL ACCIDENT LIQUIDATORS IN THE REMOTE PERIOD (BASED ON ROUTINE AND DIFFUSION-TENSOR MAGNETIC RESO...
Published 2018-01-01“…To evaluate correlation between brain structural damages and radiation exposure level for the Chernobyl nuclear power plant accident liquidators, routine and diffusion tensor magnetic resonance imaging methods are efficient to visualize and evaluate those damages; it is also important to compare magnetic resonance imaging data of liquidators with results, received for people of the same age and the same stage of cerebral vascular disease (the discirculatory encephalopathy of I and II stage), but who did not participate in the Chernobyl accident liquidation and did not suffer from other liquidation factors and radiation catastrophe aftermaths. …”
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2978
Mechanisms and potential of mesenchymal stem cell-derived exosomes for treating radiation-induced intestinal injury
Published 2025-06-01“…Radiation-induced intestinal injury (RIII) is a prevalent complication of radiotherapy for abdominal and pelvic tumors, characterized by acute and chronic damage to intestinal tissues. Current treatments are primarily symptomatic, lacking effective targeted therapies. …”
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2979
Assessing the effects of drought stress on photosynthetic performance and physiological resistance in camphor seedling leaves.
Published 2025-01-01“…Stomatal limit value (Ls) and water use efficiency (WUE) followed the order: D1>CK>D2>D3. Light energy transmission to PSI by the unit reaction center (REo/RC) initially increased then decreased, significantly smaller in D3 compared to D1. …”
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2980
Cybercrime as a New Object of Statistical Analysis
Published 2021-12-01“…Various ways of increasing the efficiency of the work of law enforcement agencies are proposed. …”
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