Early diagnosis and personalized comprehensive treatment of nasopharyngeal carcinoma based on Epstein-Barr virus-specific markers by CHEN Jie, LIANG Shuming, LIU Liting, MAI Haiqiang

“…This article reviews their current application value in NPC.…”
Get full text

Targeted Nanoparticle-Based Therapies for Nasopharyngeal Carcinoma: Enhancing Radiosensitization, Photothermal Therapy, and Diagnostics by Wang T, Wu H, Wang L, Lou N, Guo L

“…In this review, we aim to provide a comprehensive summary of the current state of targeted nanoparticle-based interventions in NPC therapy and to outline the potential for these technologies to improve therapeutic outcomes.Keywords: nasopharyngeal carcinoma, nanomedicine, nanoparticle, treatment, nanotechnology…”
Get full text

Bibliometric analysis reveals the research hotspots and trends of nasopharyngeal carcinoma immunotherapy by Gang Wang, Xiaosu Zou, Jingjin Weng, Guiping Lan, Min Li, Jiazhang Wei, Wenqian Nong, Qicong Chen, Weiwei Miao, Honglin Luo, Shenhong Qu

“…However, the literature lacks a comprehensive and objective overview of the current research status and trends of immunotherapy-related fields in NPC. …”
Get full text

Human induced neural progenitor cells generated from three-dimensional aggregate-based culture significantly improve post-stroke recovery in tMCAO mice by Zeqin Fu, Yue Hu, Yuxia Wang, Zhijie Liu, Mengyuan Li, Yanqiu Guo, Zhiwei Hu, Xingqiang Lai, Junyuan Hu, Yan Liao, Cheguo Cai

“…Results iNPCs generated from three iPSC lines displayed high NPC marker expression and an average 176-fold cell expansion over the 12-day culture period. …”
Get full text

Coacervate-pore complexes for selective molecular transport and dynamic reconfiguration by Hao Wang, Hui Zhuang, Wenjing Tang, Jun Zhu, Wei Zhu, Lingxiang Jiang

“…Looking forward, we expect the current work to establish a basis for developing liquid-based NPC analogs using a large pool of synthetic coacervates and biomolecular condensates.…”
Get full text

Research on a DC interconnection system based on a cascaded three-level converter for an island multi-energy microgrid by Xiaomin Liu, Zheng Wang, Shangke Liu, Bin Bai, Xiangnan Du

“…Subsequently, corresponding additional control strategies for DC voltage sharing and AC current sharing among C-NPC modules are designed for the island multienergy microgrid to achieve reliable power supply. …”
Get full text

Salivary MicroRNAs as Potential Noninvasive Biomarkers for the Diagnosis of Nasopharyngeal Carcinoma: Protocol for a Scoping Review by Anton Sony Wibowo, Sagung Rai Indrasari, Camelia Herdini, Dewajani Purnomosari, Sulis Ernawati

“…Globally, an estimated 133,354 cases and 80,008 deaths were attributed to NPC in 2020. Early diagnosis plays a key role in managing NPC. …”
Get full text

Technical Design and Economic Investigations for Reducing CO2 Emission considering Environmental Protection Agency Standards by Employing an Optimum Grid-Connected PV/Battery Syste... by Habib Forootan Fard, Morteza Fahim Alavi, Hassan Sharabaty, Milad Ahmadzadeh, Ibrahim Mahariq

“…Using an optimized hybrid system instead of a system without any renewables modeled in HOMER software in which the initial capital is limited reduces the cost of energy (COE) and the total net present cost (NPC) by 16% and 11%, respectively. The COE and NPC for the current system without any renewables are 0.121 ($/kWh) and 2.28 M ($), respectively. …”
Get full text

A Novel Five-Level Knight Multilevel Inverter With Phase Disposition Modulation Technique by Y. Vijaya Sambhavi, R. Vijayapriya

“…The proposed inverter is constructed by modifying the conventional 5L neutral point clamped multilevel inverter (NPC MLI). The NPC MLI architecture involves a large number of components for higher level and higher switching frequency operation. …”
Get full text

Full-Bridge ZVS-PWM Hybrid Switched-Capacitor Isolated DC-DC Converter by Anderson Alves, Ivo Barbi

“…The principle of operation, static gain, current stress in the power semiconductors, and commutation analysis are presented in this paper. …”
Get full text

PLUNC downregulates the expression of PD-L1 by inhibiting the interaction of DDX17/β-catenin in nasopharyngeal carcinoma by Ranran Feng, Yilin Guo, Meilin Chen, Ziying Tian, Yijun Liu, Su Jiang, Jieyu Zhou, Qingluan Liu, Xiayu Li, Wei Xiong, Lei Shi, Songqing Fan, Guiyuan Li, Wenling Zhang

“…Currently, the relationship between PLUNC (as a tumor-suppressor) and PD-L1 in NPC is unclear. …”
Get full text

Neutral point clamped inverter for enhanced grid connected PV system performance based on hexagonal space vector modulation by R. Palanisamy, K. Vijayakumar, Mohammad Imtiyaz Gulbarga, Mohammed Al Awadh, Liew Tze Hui

“…Additionally, the research evaluates neutral current behavior to ensure stability and compliance with grid codes. …”
Get full text

Sphingolipids and mitochondrial function, lessons learned from yeast by Pieter Spincemaille, Bruno P.A. Cammue, Karin Thevissen

“…Next, we will discuss recent findings in yeast SL research concerning a crucial signaling role for SLs in orchestrating mitochondrial function, and translate these findings to relevant disease settings such as WD and NPC. In summary, recent research shows that S. cerevisiae is an invaluable model to investigate SLs as signaling molecules in modulating mitochondrial function, but can also be used as a tool to further enhance our current knowledge on SLs and mitochondria in mammalian cells.…”
Get full text

Inability of α-cyclodextrins to accommodate cholesterol potentially underlies their lack of efficacy and ototoxicity in Niemann-Pick disease type C treatment by Yusei Yamada, Mayuko Tanaka, Yusei Ikeda, Yuki Kondo, Toru Takeo, Naomi Nakagata, Toru Miwa, Hiroki Takeda, Yorihisa Orita, Keiichi Motoyama, Taishi Higashi, Hidetoshi Arima, Takahiro Seki, Yuki Kurauchi, Hiroshi Katsuki, Katsumi Higaki, Kotaro Matsusaka, Kentaro Minami, Naoki Yoshikawa, Ryuji Ikeda, Muneaki Matsuo, Tetsumi Irie, Yoichi Ishitsuka

“…A cyclic heptasaccharide, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD), is currently under clinical investigation for treating NPC, but its ototoxicity remains problematic. …”
Get full text

Systematic Optimize and Cost-Effective Design of a 100% Renewable Microgrid Hybrid System for Sustainable Rural Electrification in Khlong Ruea, Thailand by Montri Ngao-det, Jutturit Thongpron, Anon Namin, Nopporn Patcharaprakiti, Worrajak Muangjai, Teerasak Somsak

“…Simulation results indicate the optimal configuration (S1) achieves an NPC of USD 362,687 and COE of USD 0.19/kWh, with a 100% renewable fraction, outperforming the current diesel–hydro system (NPC USD 3,400,000, COE USD 1.85/kWh, 61.4% renewable). …”
Get full text

Nickel Foam-Supported FeP Encapsulated in N, P Co-Doped Carbon Matrix for Efficient Electrocatalytic Hydrogen Evolution by Jianguo Zhong, Ting Zhang, Jianqiang Tian, Wei Gao, Yuxin Wang

“…To tackle these challenges, we developed an efficient and straightforward approach to load metal-organic framework-derived N/P co-doped carbon-encapsulated FeP nanoparticles onto a nickel foam substrate (FeP@NPC/NF-450). This catalyst exhibits exceptional HER activity in 0.5 M H₂SO₄ and 1.0 M KOH solutions, with overpotentials of 68.3 mV and 106.1 mV at a current density of 10 mA cm⁻², respectively. …”
Get full text

Design of a Tri-linked Symmetry IGCT Phase Module with Compact Structure by LI Yanyong, HU Jiaxi, SUN Baotao

“…It designed a tri-linked structural symmetry IGCT phase module based on NPC three-level circuit with high density and high reliability. …”
Get full text

Chemoimmunotherapy as induction treatment in concurrent chemoradiotherapy for patients with nasopharyngeal carcinoma stage IVa by Kun-Peng Wu, Qing-Qing Li, Xu-Qiang Luo, Xiao-Xi Wang, Yan-Zhen Lai, Dan Tian, Hong-cheng Yang, Xue-Ling Wei, Lan-Ying Wang, Qiu-Ming Li, Dao Zhu, Si-Jie Chen, Yang-Si Li

“…Background Chemoimmunotherapy is the first-line therapy for patients with recurrent or metastatic nasopharyngeal carcinoma (NPC) and is currently the main induction treatment option for patients with locoregionally advanced NPC. …”
Get full text

Tislelizumab as adjuvant therapy following endoscopic surgery for resectable recurrent nasopharyngeal carcinoma: a randomized clinical trial by Tian Wang, Xicai Sun, Hao Ding, Dehui Wang, Wanpeng Li, Haoyuan Xu, Quan Liu, Huankang Zhang, Yufei Yang, Huapeng Yu, Yurong Gu, Houyong Li

“…Currently, there is a lack of effective and well-tolerated adjuvant treatment regimens. …”
Get full text

The evolution of prophylactic neck irradiation in nasopharyngeal carcinoma: Changing concepts and irradiation ranges by Wenjun Liao, Yue Zhao, Shichuan Zhang

“…Abstract The approach to prophylactic neck irradiation in nasopharyngeal carcinoma (NPC) has undergone significant changes. For decades, prophylactic whole‐neck irradiation has been the standard for all patients with NPC; however, it is linked to a high risk of late complications. …”
Get full text