IFP35, a novel DAMP, aggravates neuroinflammation following acute ischemic stroke via TLR4/NF-κB/NLRP3 signaling by Mengmeng Zhang, Bingnan Guo, Xiaowei Zhang, Dong Han, Lanxin Lv, Xiaoqing Yan, Chenglei Su, Dafei Chai, Ningjun Zhao, Xianliang Yan, Shuqun Hu

“…Conclusions This study revealed IFP35 as a novel DAMP released during cerebral ischemia that promotes neuroinflammation and injury, expanding the current understanding of inflammatory networks following stroke.…”
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Effectiveness of biomarker-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection: the BATCH RCT by Cherry-Ann Waldron, Philip Pallmann, Simon Schoenbuchner, Debbie Harris, Lucy Brookes-Howell, Céu Mateus, Jolanta Bernatoniene, Katrina Cathie, Saul N Faust, Josie Henley, Lucy Hinds, Kerry Hood, Chao Huang, Sarah Jones, Sarah Kotecha, Sarah Milosevic, Helen Nabwera, Sanjay Patel, Stéphane Paulus, Colin VE Powell, Jenny Preston, Huasheng Xiang, Emma Thomas-Jones, Enitan D Carrol

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Single-cell and spatial atlas of glioblastoma heterogeneity: characterizing the PCLAF+ subtype and YEATS4’s oncogenic role by Siqi Ma, Yuwei Sun, Shaowei Zheng, Yilong Fu, Liangyu Wang, Dun Liu, Henan Jiao, Xuqiang Zhu, Xueyuan Li, Dongming Yan, Di Chen, Zi Ye

“…These findings provided novel targeted intervention strategies to address GBM heterogeneity and treatment resistance, offering promising avenues for overcoming current therapeutic limitations.…”
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An implementation facilitation intervention to improve the musculoskeletal X-ray reporting by radiographers across London by Paul Lockwood, Christopher Burton, Theresa Shaw, Nicholas Woznitza, Emma Compton, Heather Groombridge, Natasha Hayes, Uday Mane, Anna O’Brien, Stephanie Patterson

“…Abstract Background The National Healthcare Service (NHS) radiology service delivery in London is representative of the current pressures and challenges faced in England of Musculoskeletal (MSK) X-ray reporting workforce shortages, and national turnaround time (TATs) targets. …”
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Development of Explainable Machine Learning Models to Identify Patients at Risk for 1-Year Mortality and New Distant Metastases Postendoprosthetic Reconstruction for Lower Extremit... by Jiawen Deng, BHSc, Myron Moskalyk, BHSc, MSc, Madhur Nayan, MD, PhD, Ahmed Aoude, MEng, MD, FRCSC, Michelle Ghert, MD, FRCSC, Sahir Bhatnagar, PhD, Anthony Bozzo, MSc, MD, FRCSC

“…We performed a secondary analysis of data from the Prophylactic Antibiotic Regimens in Tumor Surgery trial, which included 604 patients. …”
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Identification of Priority Areas for Ecological Restoration at a Small Watershed Scale: A Case Study in Dali Prefecture of Yunnan Province in China by Qiyuan Zhou, Qiuping Zhu, Yu Feng, Jinman Wang

“…To address this gap, this study selected Dali Prefecture in Yunnan Province, a region characterized by dense river networks, as the research area to identify the priority areas of ecological restoration. …”
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An integrative review of new nurse practitioners’ experiences in rural healthcare practice by Candace Stidolph, Jennifer Kawi, Catherine Dingley, Ann Marie Hart, Jarod Giger, Rebecca Benfield, Andrew Thomas Reyes

“…This integrative review aimed to analyze and synthesize various types of empirical reports and theoretical articles about new NPs' experiences in rural primary healthcare practice; identify current literature gaps; and discuss implications for education, policy, and further research. …”
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Review of Research on Foundation Scour of River-Crossing Bridges by WANG Lu, LIU Hong-wei, WEI Kai, Bruce Melville, NIE Rui-hua

“…To build a more comprehensive understanding of foundation scour of river-crossing bridges, future studies should better integrate flume experiments, prototype monitoring, numerical modeling, theoretical analysis, artificial neural networks, and deep learning methods. …”
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PREdiction and Diagnosis using Imaging and Clinical biomarkers Trial in Traumatic Brain Injury (PREDICT-TBI) study protocol: an observational, prospective, multicentre cohort study... by Siva Senthuran, Lewis Campbell, Jennifer Fleming, Virginia Newcombe, Michael Reade, Silvia Manzanero, James Walsham, Nathan Brown, Xuan Vinh To, Clifford Pollard, Fatima Nasrallah, Judith Bellapart, Esther Jacobson, Jason Meyer, Janine Stuart, Tracey Evans, Shekhar S Chandra, Jason Ross, James McCullough

“…Study findings will be disseminated by peer-review publications and presented at national and international conferences and clinical networks.Trial registration number ACTRN12620001360909.…”
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Crab shell polypeptides enhance calcium dynamics and osteogenic activity in osteoporosis by Xiaolei Dong, Xiaolei Dong, Guangmin Zhang, Chong Sun, Hui Zhang, Jinmeng Zhen, Xinlei Li, Xiaohui Xu, Jiane Liu, Xiangzhong Zhao, Yiming Zhang, Linlin Liu, Shaoqi Tian, Daijie Wang, Zheng Wang, Zheng Wang, Bing Li

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The WHEAT pilot trial—WithHolding Enteral feeds Around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: a multicentre, electronic patient recor... by Neena Modi, Jon Dorling, Chris Gale, Tjeerd Van Staa, Louise Linsell, Ursula Bowler, Ed Juszczak, Mark A Turner, Sena Jawad, Amanda Forster, Andy King, Jenny McLeish, Helen Robberts, Kayleigh Stanbury

“…The trial will recruit in two neonatal networks in England for 9 months. Data collection will continue until all infants have reached 40+0 corrected gestational weeks or neonatal discharge. …”
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Representation of Iran among Iraqi social media users (A case study of Facebook users after the defeat of ISIS until the martyrdom of Hajj Qassem Soleimani) by mohsen finizadeh bidgoli

“…However, in today's world—and likely in the future—soft power and public diplomacy offer some of the most relevant frameworks for understanding power’s current form and function. At the same time, the growing importance of social networks has become an undeniable reality. …”
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Addictive behaviour of adolescents and young men in the education system: Review of psychological and pedagogical research by S. A. Minyurova, O. V. Kruzhkova, I. V. Vorobyeva, A. I. Matveeva

“…Not only chemical addiction leads to serious problems, but also social networks, smartphones, gaming addictions lead to a significant decrease in the level of physical and mental health of adolescents and young men, socio-psychological maladaptation in society, violation of their psychological well-being and in critical cases – the development of suicidal risks. …”
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Studying Spatiotemporal Changeability of Oak Forests in Zagros in Response to Rainfall Variation by Zahra Alirezai, Amir Gandomkar, Morteza khodagholi, Alireza Abbasi

“…Spatial analysis of the implementation of the greenness estimator model showed that the rainfall threshold of oak greenery (EVI> 0.4) was equal to 320 mm, above which the EVI index increased by 0.88 for each millimeter of rainfall growth of the studied oaks. …”
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Implementing an exercise oncology model to reach rural and remote individuals living with and beyond cancer: a hybrid effectiveness-implementation protocol for project EXCEL (EXerc... by Daniel Sibley, Margaret L McNeely, Anil Abraham Joy, Nicole Culos-Reed, Sarah McKillop, Guanmin Chen, Robin Urquhart, Nicholas Giacomantonio, Scott Grandy, Melanie Keats, Lauren C Capozzi, Miroslaw Rajda, Daniel Santa Mina, Leslie Hill, Danielle Bouchard, Julianna Dreger, Chad W Wagoner, Colleen Cuthbert, George J Francis, Manuel Ester, Emma McLaughlin, Max Eisele, Jodi Langley, Joy Chiekwe, Thomas Christensen, Kristin Campbell, Amanda Wurz, Rosemary Twomey, David Langelier, Chris Blanchard, Erin McGowan, Travis Saunders, Robert Rutledge, Tallal Younis, Lori Wood, Stephanie Snow, Judith Purcell, Carolina Chamorro Vina, Shabbir Alibhai, David Eisenstat, Beverly Wilson, Danielle Briand, Terri Billard, Naomi Dolgoy, Paula Ospina-Lopez, Shaneel Pathak

“…To improve accessibility to exercise oncology programs, we have designed the EXercise for Cancer to Enhance Living Well (EXCEL) study.Methods and analysis EXCEL is a hybrid effectiveness-implementation study. …”
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Antiprotozoal Natural Products from Endophytic Fungi Associated with Cacao and Coffee by Cristopher A. Boya P., Candelario Rodriguez, Randy Mojica-Flores, Jean Carlo Urrutia, Víctor Cantilo-Diaz, Masiel Barrios-Jaén, Michelle G. Ng, Laura Pineda, Alejandro Llanes, Carmenza Spadafora, Luis C. Mejía, Marcelino Gutiérrez

“…Tandem liquid chromatography–mass spectrometry (LC–MS) analysis of the organic extracts from different strains via the feature-based Global Natural Products Social (GNPS) molecular networking platform allowed us to dereplicate a series of metabolites (<b>10</b>–<b>23</b>) in the extracts. …”
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Identifying and Leveling Factors Affecting Women's Leisure Time with Emphasis On Physical Activities by Shahoo Zamani Dadanh, Shirin Zardoshtiyan

“…Gimmez et al. (2021) investigated the sports and free time activities of Muslim women and stated that sporting events can foster nationalism. An analysis of current political and public discourses on Muslim women's sports and free time showed that this group is facing many limitations. …”
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Proceedings of the 15th European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals by Sophie Tourdot, Karien Bloem, Lysie Champion, Anne S. De Groot, Axel Ducret, Patrick Garidel, Joanna Grudzinska-Goebel, Michael Gutknecht, Timothy Hickling, Frank Horling, Marina Ichetovkin, Alison Johnson, Issa Jyamubandi, Anette Karle, Arno Kromminga, Ebru Aydin Kurtulmus, Floris Loeff, Bernard Maillere, Lydia Michaut, Francesca Minelli, Morten Nielsen, Vivek Nayak, Robert Nelson, Marc Pallardy, Sofie Pattyn, Joao Pedras-Vasconelos, Elise Pepermans, Alain Poyau, Matthias Reichel, Amy Rosenberg, Zuben Sauna, Manisha Saxena, Noel Smith, Veerle Snoeck, Lester Thoo, Michael Tovey, Daniela Verthelyi, Rene Wuttke, Daniel Yerly, Daniel Kramer

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Progress and Challenges in Morphodynamics of Braided Rivers in Source Region of Yangtze River by LI Zhi-wei, OUYANG Wei-qi

“…An integrated research framework that combines process analysis, threshold identification, and evolutionary trend modeling should be established. …”
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Designing an entrepreneurial ecosystem model in a university with a knowledge-based approach by Nahid Mir, Amin Rahimi Kia, Mehry Daraei

“…AbstractThe aim of the current research is to Designing an entrepreneurial ecosystem model in the university with a knowledge-oriented approach. …”
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