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381
Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4
Published 2025-12-01“…Hypoxia-inducible factor-1 (HIF-1) activation plays an essential role in CKD; however, the specific contribution of tubular HIF-1 to renal TIF remains unclear. In the current study, the mechanism underlying HIF-1-mediated TIF was investigated. …”
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382
Job insecurity, work passion, and work–life balance in diverse work arrangements
Published 2025-05-01“…Orientation: The coronavirus disease 2019 (COVID-19) pandemic shifted work settings, revealing gaps in current literature on how work arrangements affect employee experiences and well-being. …”
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383
Ethnozootechnical Perspectives on the Decline of Traditional Knowledge About Local Goat and Sheep Breeds in the Semi-Arid Region of Paraíba, Brazil
Published 2025-06-01“…Two workshops were held to assess the diversity of breeds in the past landscape (PP) and current landscape (PA), using the Recall technique. …”
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384
Assessing Immunization Coverage and the Negative Impact of Local Vaccine Production Cessation in Ecuador
Published 2025-03-01“…For BCG, median coverage decreased from 100% during the production period to 87.8% post-cessation (<i>p</i> < 0.0001). …”
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385
Effect of social perspectives in the relationship between suicidal ideation and depression among young women in slums of Kampala, Uganda
Published 2025-06-01“…Conclusion Intervention programs geared towards building resilience among young women in Uganda may reduce suicidal ideation directly or indirectly by decreasing depression, especially in urban slum settings.…”
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386
Jian-Pi-Gu-Shen-Hua-Yu Decoction Alleviated Diabetic Nephropathy in Mice through Reducing Ferroptosis
Published 2024-01-01“…Diabetic nephropathy (DN), one of the most frequent complications of diabetes mellitus, is a leading cause of end-stage renal disease. However, the current treatment methods still cannot effectively halt the progression of DN. …”
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387
Study of Different Recycling Approaches for Gypsum-Based Composites with Recycled Rubber Aggregates
Published 2025-02-01“…Therefore, this research outlines the potential of gypsum recycling with recycled rubber aggregates, thus promoting the circularity of construction products and decreasing the building’s environmental footprint. This represents a novelty compared to current studies, which are more oriented towards recycling and recovery of waste from conventional plasterboards.…”
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388
Comparing the technical and individual possession statistics of academy players across different age groups in match-play.
Published 2025-01-01“…<h4>Conclusion</h4>Attacking players (AM & ST) are required to move the ball quicker as they progress from U16 to U23's within the current English football academy. Further exploration is required to assess if these changes are context specific given requirements of those age groups.…”
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389
Micro nutrients as immunomodulators in the ageing population: a focus on inflammation and autoimmunity
Published 2024-12-01“…For example, it points out the modulatory effects of vitamin D on both innate and adaptive immunity, with a specific focus on its ability to suppress pro-inflammatory cytokines synthesis while enhancing regulatory T-cell function. In the same context, also zinc is described as important nutrient for thymic function and T-cell differentiation but exhibits immunomodulatory functions by decreasing inflammation. …”
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390
A Review of Renewable Energy Technologies in Municipal Wastewater Treatment Plants (WWTPs)
Published 2024-12-01“…Through a comprehensive review of current practices and emerging technologies, this study underscores the transformative potential of these innovations in advancing low-emission wastewater management.…”
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391
Impacts of CACNB4 overexpression on dendritic spine density in both sexes and relevance to schizophrenia
Published 2024-12-01“…Overexpressing the gene that encodes the voltage-gated calcium channel subunit β4, CACNB4, selectively reduced small spine density in vitro. In the current study we extended this observation in an intact mammalian system within a relevant neurodevelopmental context. …”
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392
Administrator Turnover: The Roles of District Support, Safety, Anxiety, and Violence from Students
Published 2024-11-01“…Findings highlight the importance of district support of administrators for reducing mental health concerns and transfer/quit intentions in the context of student violence against school administrators. …”
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393
A Sociological study of the Relationship between Smartphone Addiction and Phubbing Case Study18-29 Year Old Females of Ramhormoz City
Published 2024-12-01“…The statistical population of the current research includes all women aged 18 to 29 in Ramhormoz city. …”
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394
Continuing the continuous harvests of food production: from the perspective of the interrelationships among cultivated land quantity, quality, and grain yield
Published 2025-01-01“…This successive increase in food production in the context of decreasing acreage and ecological deterioration of CL depend mainly on the amount of chemical fertilizer usage, the total power of agricultural machinery and rural electricity consumption. …”
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395
Cognitive Outcomes and Functional Performance for Patients After Open Heart Surgery
Published 2024-04-01“… Context: Open heart surgery is a lifesaving procedure for patients who need coronary artery bypass graft (CABG) and heart valve replacement or repair (HVR). …”
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396
Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension
Published 2025-07-01“…Adoptive transfer of aGM-treated BMDMs into SSHTN mice resulted in decreased renal trafficking. Additionally, aGM treatment of BMD-Macs, CD38+ BMD-M1 Macs, BMD-DCs, and CD38+ BMD-cDC2s led to decreased pro-inflammatory gene expression. …”
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397
Strategies for adaptation of Russian commercial banks to innovative technologies
Published 2025-07-01“…The article discusses the strategies of the bank in the innovation sphere, which are important components of general development strategies, their content and the order of choice in the context of digitalization of the economy and global changes in the world banking system. …”
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398
An Agent-Based Simulation and Optimization Approach for Sustainable Urban Logistics: A Case Study in Lisbon
Published 2025-05-01“…The research focuses on a real-world case study, comparing the company’s current operational scenario with an optimized scenario generated through a PDP-TW model adapted from the literature. …”
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399
The implementation of Safety Management Systems in healthcare: a systematic review and international comparison
Published 2025-03-01“…Safety management systems need to be context-specific to be effective. Evidence on the use of safety management systems in health care is therefore needed to inform policy decisions. …”
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400
Mapping evidence of spinal manipulation therapy for headaches in South Africa: a scoping review of grey literature
Published 2025-08-01“…Abstract Objective Spinal manipulative therapy (SMT) has been demonstrated to be an effective management approach for primary headaches; however, current literature often excludes data from South Africa (SA). …”
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