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261
Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons
Published 2025-06-01“…Therefore, in the present study we aim to characterise metabolomic profiles of insomnia and CI alone in order to address a significant gap in current research regarding the pathways through which insomnia may lead to CI in older persons. …”
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262
Protocol for a randomized controlled trial of patient–portal–based screening for substance use among people with HIV
Published 2025-08-01“…This will lay the groundwork for the second aim, the focus of the current manuscript, RCT to measure the effectiveness of a population health, patient portal-based substance use screening program. …”
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263
Impact of Climate Change on the Narrow Endemic Herb Psilopeganum sinense (Rutaceae) in China
Published 2025-03-01“…Our results not only provide a scientific basis for managing P. sinense resources in the context of climate change but also serve as an important reference for restoring wild P. sinense populations.…”
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264
Dynamics of educational activity of students under the influence of digitalisation
Published 2021-10-01“…This study is based on the use of specific approaches to industry-specific sociological knowledge (youth and education): community, system, structural-functional, institutional, temporal, thesaurus, network, panoramic (pedagogical science). The current research employs the results of a mass survey conducted among students (N = 1825, 19 universities of the Sverdlovsk region) according to the authors’ method. …”
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265
Complementary Strategy of Maternal Immunization with RSVpreF Vaccine and Monoclonal Antibodies for the Prevention of Respiratory Syncytial Virus Among Italian Infants: A Cost-Effec...
Published 2025-07-01“…Methods Using a model (with a cohort framework and a Markov-type process) specifically adapted to the Italian context, the study provided cost-effectiveness and cost-utility assessment of prevention strategies adding the maternal vaccination to the existing immunization opportunities with palivizumab or nirsevimab administered to high risk and unprotected infants. …”
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266
Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria...
Published 2025-03-01“…These findings support the ongoing use of AL with a single dose of PQ as the primary treatment option for uncomplicated P. falciparum infections in the study area. In the context of the emergence and spread of partial artemisinin-based combination therapy(ACT) resistance in Africa, regular monitoring of the efficacy of current artemisinin-based combinations is recommended for the early detection of emerging drug resistance in the study setting and beyond.…”
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267
Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH).
Published 2019-01-01“…Activation of PPARα pathway was supported by observed decrease in serum lipid levels. Our findings provide important insights into the role of TSP-1 in context of NAFLD/NASH and TSP-1 may be a target of interest to develop anti-fibrotic therapeutics for NAFLD/NASH.…”
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268
Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies
Published 2023-01-01“…The problem of correct in time diagnostics has the socially significant nature. Currently, international consensus and national protocols for the treatment and prevention of venous thromboembolism are regularly reviewing. …”
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269
The Effect of Training Experience on Cardiac Morphology in Resistance Exercise Practitioners: A Study on Left Ventricular Systolic and Diastolic Parameters and Left Atrium Mechanic...
Published 2024-12-01“…In this context, cohort studies are needed to analyze in detail the reasons for the decrease in diastolic parameters in these individuals.…”
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270
Legal Challenges of Marine Insurance Laws in the Use of Unmanned Ships
Published 2025-03-01“…While such defects can lead to severe incidents, most current insurance policies do not cover these risks. …”
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271
Paradigms of the agricultural system in times of COVID-19
Published 2021-05-01“…Until the end of the 20th century, world agriculture underwent a transition towards a new technological paradigm, very different from that of the green revolution, based on the current “bio” revolutions, in which human beings have transformed biodiversity by placing it at their service1. …”
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272
Indian Himalayan Arabidopsis thaliana population reflects deep history and might be the source of species expansion in the eastern edge
Published 2025-07-01“…The genetic diversity of Indian populations was found to decrease towards east and west of its peripheral region. …”
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273
Re-use of Building Products in the Netherlands
Published 2019-01-01“…This research departs from the desire to understand the practice of reuse of building products from a systemic standpoint, to illuminate its current condition and help to foresee future perspectives. …”
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274
Changes in tree-ring wood density of European beech (Fagus sylvatica L.), silver fir (Abies alba Mill.), and Norway spruce (Picea abies (L.) H. Karst.) in European mountain forests...
Published 2024-12-01“…Abstract Key message We found a significant increase in the latewood density of European beech, and a decrease in the latewood and mean wood density of silver fir and Norway spruce in European mountain forests over the period 1901–2016. …”
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275
miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway
Published 2025-03-01“…Abstract Purpose Polycystic ovary syndrome (PCOS) is currently recognized as a condition that affects several systems in the body, including the reproductive, endocrine, and cardiovascular systems. …”
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276
Banking Models Under the Impact of the Post-Crisis Organizational Changes Apt to Confer Sustainable Financial Stability - Romanian Experience
Published 2012-06-01“…The banking model practiced in Romania continues to be the traditional one. Currently, the most important challenges of the Romanian banking system are the growth of the non-performing loans, the loans in foreign currency to unhedged borrowers, the pressure to meet the Basel III requirements, as well as the possibility that the exposure of foreign banks towards Romania to decrease.…”
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277
Sustainable agricultural mechanization in Timor-Leste: status, challenges and further action
Published 2024-01-01“…Beyond this, a reform of the current government mechanization hire schemes is needed: integrated approaches, as found from business model analyses and training exercises during field missions, are needed, that entail context-specific solutions for targeted rural communities, with special attention given to participatory extension, inclusive co-validation of technologies, and private sector-led business model development around mechanization service delivery. …”
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278
Turkey’s Nuclear Energy Ambitions: Past Efforts, Present Strategies, and Future Directions
Published 2025-06-01“…Nuclear power plants, popularized by the promise of decreasing dependency on foreign resources and providing supply security, meet 10% of the world’s energy needs as of 2023. …”
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279
Impact of a Saline Soil Improvement Project on the Spatiotemporal Evolution of Groundwater Dynamic Field and Hydrodynamic Process Simulation in the Hetao Irrigation District
Published 2025-05-01“…Reducing irrigation to 80% of the current water supply of the Yellow River enables groundwater level stabilization (2.05 ± 0.12 m burial depth) within 5–7 years. …”
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280
An experimental study on the effects of electronic medicinal product information on vaccine hesitancy
Published 2025-04-01“…We conclude, by relating the current study to the relevant literature, that salience and information overload could be the main driver of vaccine hesitancy in the context of this study.…”
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