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  1. 461

    Stochastic simulation modeling of the economics of providing additional living space for housed dairy cows by Jake S. Thompson, Chris D. Hudson, Jon N. Huxley, Jasmeet Kaler, Martin J. Green

    Published 2024-12-01
    “…When building a new shed with a high living space versus control at a 4.00% interest rate, a median net return on infrastructure investment of +£23.00 per cow per year was identified (range –£25.91 to +£64.16 for 10th to 90th percentile). Since decreased living space is likely to lead to poorer welfare, it can be considered a negative production externality associated with current production systems, the cost of which should also be accounted for when analyzing the economics of housing. …”
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  2. 462
  3. 463

    Neutrophil-to-Lymphocyte ratio as surrogate for JAK2V617F suppression and event-free survival in polycythemia vera by Tiziano Barbui, Arianna Ghirardi, Victoria Empson, Francesca Fenili, Giuseppe Gaetano Loscocco, Annalisa Condorelli, Alessandra Iurlo, Daniele Cattaneo, Elena Rossi, Valerio De Stefano, Paola Guglielmelli, Christoph Klade, Heinz Gisslinger, Alessandro Rambaldi, Joseph M. Scandura, Alessandro Maria Vannucchi

    Published 2025-08-01
    “…Abstract Chronic systemic inflammation is a key driver of polycythemia vera (PV) progression, but the immunomodulatory effects of current treatments remain poorly defined. The neutrophil-to-lymphocyte ratio (NLR) is an accessible biomarker of systemic inflammation proven in other contexts, but its role in monitoring PV disease activity has not been established. …”
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  4. 464

    Climate and human activities alter coupling of soil macro- and micronutrients: Evidence from a long-term experiment in typical steppes by Yi Zhou, Shenghua Chang, Xiaojuan Huang, Wenjun Wang, Fujiang Hou, Yanrong Wang, Zhibiao Nan

    Published 2025-04-01
    “…Our results showed decreases in soil Zn and Fe stocks, alongside increases in Cu, SOC, and STN stocks over time. …”
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  5. 465

    NECROSIS AS A COMPLICATION OF LOCAL ANESTHESIA IN DENTISTRY by V.V. Lepsky, C. V. Osik

    Published 2018-03-01
    “…However, as a rule, most of the groups of painkillers contain vasoconstrictors of the cartridge, such as adrenaline hydrochloride, noradrenaline, although the last one is currently banned for use because of the complications that it can cause. …”
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  6. 466

    MHD analysis of couple stress nanofluid through a tapered non-uniform channel with porous media and slip-convective boundary effects by P. Deepalakshmi, G. Shankar, E.P. Siva, D. Tripathi, O. Anwar Bég

    Published 2025-05-01
    “…The current research addresses the peristaltic transport mechanism that propels fluid through a conduit through rhythmic contraction and relaxation of the conduit walls, a phenomenon evident in numerous biological systems, including the gastrointestinal tract. …”
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  7. 467

    Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

    Published 2023-08-01
    “…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
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  8. 468
  9. 469

    SOUTH AFRICAN USERS’ FUNCTION AND EXPERIENCE WITH A MAGNETORHEOLOGICAL MICROPROCESSOR KNEE: A MIXED METHODS STUDY by Surona Visagie, Benje Theron

    Published 2025-06-01
    “…CONCLUSION: This study provides context specific scientific evidence that may support funding decisions for MPKs in South Africa. …”
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  10. 470

    Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

    Published 2025-07-01
    “…(Malvaceae), abbreviated as TFA, in the context of MAFLD. Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. …”
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  11. 471

    Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT by Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger

    Published 2024-10-01
    “…Modelling suggested that provision of oral tenofovir/emtricitabine pre-exposure prophylaxis increased human immunodeficiency virus testing, with anti-retroviral therapy initiation at diagnosis, and reductions in the level of condom-less sex, that each played an important role in decreasing human immunodeficiency virus incidence among men who have sex with men, and that the current human immunodeficiency virus incidence would have been double what it is if any one of them had not occurred. …”
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  12. 472

    Comparative Ethics of Modern Payment Models by Jacob Riegler

    Published 2023-01-01
    “…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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  13. 473

    Comparative Ethics of Modern Payment Models by Jacob Riegler

    Published 2023-01-01
    “…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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  14. 474

    Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning by Bronagh Walsh, Carole Fogg, Tracey England, Sally Brailsford, Paul Roderick, Scott Harris, Simon Fraser, Andrew Clegg, Simon de Lusignan, Shihua Zhu, Francesca Lambert, Abigail Barkham, Harnish Patel, Vivienne Windle

    Published 2024-10-01
    “…Mean face-to-face appointments were generally similar within frailty categories across age groups, but with a notable decrease in appointments with older age in the severe category. …”
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  15. 475

    Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

    Published 2025-07-01
    “…We interviewed 52 men and women from Black African and Caribbean communities in London who had been identified as having previous or current problems adhering to their medication. Two separate analyses were conducted. …”
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  16. 476

    Is social theory losing its relevance? A call for social impact and cocreation from dialogic sociology by Elisabeth Torras-Gómez, Mar Joanpere, Carmen Elboj, Mengna Guo, Esther Oliver, Ane Lopez de Aguileta, Marta Soler-Gallart

    Published 2025-06-01
    “…Abstract Currently, the interest in and use of social theory by policy-makers, organizations, and citizens have decreased worldwide. …”
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  17. 477

    Health and economic evaluation of cytomegalovirus vaccination strategy among young women in China: a modelling study by Bin Zhang, Gang Qin, Jun-Tao Shu, You-Jia Wu, Yin-Hua Jiang, Yi-Wen Ge, Meng-Zhao Yin

    Published 2025-05-01
    “…Background Congenital cytomegalovirus (cCMV) infection imposes a substantial economic burden on both families and society in China. There is currently a paucity of dynamic models to study cytomegalovirus (CMV) vaccination strategies for China’s high-seroprevalence population (over 95%). …”
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  18. 478

    Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

    Published 2023-03-01
    “…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
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  19. 479

    Comparative abundance and diversity of populations of the Pseudomonas syringae and Soft Rot Pectobacteriaceae species complexes throughout the Durance River catchment from its Fren... by Morris, C.E., Lacroix, C., Chandeysson, C., Guilbaud, C., Monteil, C., Piry, S., Rochelle Newall, E., Fiorini, S., Van Gijsegem, F., Barny, M.A., Berge, O.

    Published 2023-09-01
    “…The dynamics of human and animal pathogens in catchments have been widely studied in a large variety of contexts allowing the optimization of disease risk reduction. …”
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