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381
Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia
Published 2025-06-01“…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
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382
Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1
Published 2025-03-01“…Overexpression of the splicing factor 3b subunit 1 (SF3B1) and neurogenic locus notch homolog protein 1 (NOTCH1) factors is typically found in chronic lymphocytic leukemia (CLL), leading to the development of chemotherapy resistance. Objective The current investigation aims to evaluate the chemosensitivity of CLL cells by blocking NOTCH1 and SF3B1 using chitosan lactate (CL) nanoparticles (NPs). …”
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383
Job Satisfaction Analysis of Nurses, who Work in Neurology and Neurosurgery Units
Published 2022-12-01“…Satisfaction, facing problems and motivation are currently strategic points to be analysed in terms of nurses’ work. …”
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384
Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants...
Published 2025-03-01“…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
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385
High prevalence of the hotspot complement factor I p.Ile357Met pathogenic variant in Tunisian atypical hemolytic uremic syndrome patients: report of three new cases and review of t...
Published 2025-08-01“…The recurrence of this variant in the Tunisian cohort led us to suggest that it could be characteristic of the Tunisian population.MethodsIn this context, we conducted the current study which included 8 adults and three children with suspected aHUS and decreased factor I levels, as well as one relative. …”
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386
Wisdom of the Established Pattern
Published 2023-06-01“…According to their example, if someone is opposed to increasing as well as decreasing the average human intelligence, they need a good reason for why the current level is optimal. …”
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387
ChatGPT's perspectives on real numbers, straight lines, and probability—A quantitative study on the influence of prompting
Published 2025-07-01“…Large language models like ChatGPT are currently a hot topic in mathematics education research. …”
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388
Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study
Published 2025-06-01“…ABSTRACT: Background context: Posterior lumbar fusion (PLF) is a common procedure, for which patients with systemic conditions may be considered. …”
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389
Presentation of Financial Assets in the Statistics of Foreign Economic Relations
Published 2023-05-01“…The paper identifies the main directions for the statisticalstudy of financial assets, based on current international standards, taking into account national practice. …”
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390
Registry-based surveillance of paediatric home respiratory support in Switzerland: methodology and initial findings
Published 2025-06-01“…This first publication aims to present the SwissPedHRS methodology and describe the current paediatric population with home respiratory support in Switzerland and its evolution from 2001 to 2023. …”
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391
A Sociological study of the Relationship between Smartphone Addiction and Phubbing Case Study18-29 Year Old Females of Ramhormoz City
Published 2024-12-01“…The statistical population of the current research includes all women aged 18 to 29 in Ramhormoz city. …”
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392
Reassessing immediate coal phase-out: Dual imperatives of capacity control and renewables expansion in China’s net-zero strategy
Published 2025-09-01“…Broader context: Reducing CO2 emissions in power systems is crucial for China in achieving its net-zero emission target. …”
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393
SolarSegNet: A multimodal frequency-aware network for photovoltaic power stations extraction using Sentinel-1 and Sentinel-2 images in coastal China
Published 2025-08-01“…Current deep learning-based remote sensing methods for photovoltaic (PV) power stations identification primarily focus on inland high-irradiance areas, but exhibit significant limitations in accurately delineating boundary of multi-scale PV power stations in coastal regions. …”
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394
Winter wheat yield responses to growing degree days: Long-term trends and adaptability in major producing areas of China
Published 2025-01-01“…This study provides crucial insights into current challenges and offers a foundation for future research on yield forecasting under varying climate scenarios.…”
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395
Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases
Published 2025-04-01“…Helminth infection can also negatively impact vaccine efficacy by suppressing B cell activity, reducing antibody levels, and decreasing vaccine effectiveness against infectious diseases. …”
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396
The association between dietary fat quality and quantity and hospitalization duration in COVID-19 in Iranian patients: a cross-sectional study
Published 2025-04-01“…Additionally, there was a positive association between CSI levels and DH. Current findings indicate that the quality and balance of dietary fats may play a crucial role in modulating inflammatory responses and clinical outcomes.…”
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397
Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review
Published 2025-02-01“…Following this, the specific interacting contexts and underlying mechanisms were appraised, and the synthesis focused on developing context–mechanism–outcome configurations (CMOCs), which formed the basis of the emerging programme theory. …”
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398
DEVELOPMENT PROSPECTS OF THE RUSSIAN MARKET OF TECHNICAL SERVICING AND REPAIR IN THE СONTEXT OF A PANDEMIC
Published 2021-02-01“…Currently, at a time of decreasing automotive production caused by the suspension of the plants in the period of lockdown, the reduction in purchasing power of communities connected with the risk of unemployment occurrence in consequence of business failures, the decline in wages and lower vacancy rates, is foreseen reduced demand for new cars against the background of significant increase in sales volumes in the used cars market segment and, therefore, sharp increase in demand for car services performing technical servicing and repair. …”
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399
Determining the Teachers' Attitude towards "Mistake" and "Making Mistakes" in the Learning Process and Improving the Culture facing it (case study: elementary school students)
Published 2024-03-01“…With these perceptions, teachers may react differently to students' mistakes. In this context, the teacher's attitude, his awareness and experience of the impact of mistakes on progress and success in dealing with students' mistakes are very important. …”
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400
Does Beta Explain Global Equity Market Volatility – Some Empirical Evidence
Published 2013-06-01“…In this study, we examine Capital Asset Pricing Model (CAPM) in its international context (ICAPM) using the monthly equity returns for 26 countries (18 developed and 8 emerging markets) between July 1996 and June 2011 and adopting the US investor’s perspective. …”
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