The role of anifrolumab in reshaping the treatment landscape of extra-renal systemic lupus erythematosus by Fulvia Ceccarelli, Matteo Piga, Alessandra Bortoluzzi, Laura Coladonato, Micaela Fredi, Daniele Mauro, Chiara Tani, Luca Iaccarino

“…Hypothetical scenarios derived from clinical practice were examined to identify real-life contexts suitable for the early initiation of anifrolumab treatment. …”
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Protocol for a randomized controlled trial of patient–portal–based screening for substance use among people with HIV by Eric Roessler, Daniela Zimmer, Jon Grant, Harold Pollack, Basmattee Boodram, Jessica Schmitt, Jessica Schmitt, Eleanor Friedman, Jade Pagkas-Bather, Jade Pagkas-Bather, Russell A. Brewer, Jessica Ridgway, Neda Laiteerapong, Neda Laiteerapong

“…BackgroundAchieving Equity in Patient Outcome Reporting for Timely Assessments of Life with HIV and Substance Use (ePORTAL HIV-S) is a research project funded by the National Institute for Drug Abuse to implement and evaluate multi-level interventions to decrease barriers to substance use screening and treatment for PLWH. …”
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Impact of Climate Change on the Narrow Endemic Herb Psilopeganum sinense (Rutaceae) in China by Ruixiong Deng, Kaitong Xiao, Xin Chen, Beibei Huang, Haoran Li, Lin Wu, Hang Ning, Hui Chen

“…Our results not only provide a scientific basis for managing P. sinense resources in the context of climate change but also serve as an important reference for restoring wild P. sinense populations.…”
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Re-use of Building Products in the Netherlands by Loriane Icibaci

“…As the anthropogenic environment evolves, it is relevant to comprehend how fit the industrial system is in this dynamic context, leading to the second part of the study: The evolution of the housing stock as dynamic reserves (supply of reusable products). …”
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Dynamics of educational activity of students under the influence of digitalisation by D. Yu. Narkhov, E. N. Narkhova, D. V. Shkurin

“…The fixation of qualitative changes in educational activity in non-standard conditions, along with the development of a theoretical basis for the digital educational community of students, is necessary for making qualified managerial decisions.The aim of the present research was to identify the factors and dynamics of students as a digital educational community in the context of self-isolation and online learning.Methodology and research methods. …”
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Complementary Strategy of Maternal Immunization with RSVpreF Vaccine and Monoclonal Antibodies for the Prevention of Respiratory Syncytial Virus Among Italian Infants: A Cost-Effec... by Barbara Polistena, Fabio Midulla, Giovanni Sotgiu, Daniela d’Angela, Roberto Di Virgilio, Federico Spandonaro

“…Methods Using a model (with a cohort framework and a Markov-type process) specifically adapted to the Italian context, the study provided cost-effectiveness and cost-utility assessment of prevention strategies adding the maternal vaccination to the existing immunization opportunities with palivizumab or nirsevimab administered to high risk and unprotected infants. …”
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Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria... by Bontu Abate, Bokretsion Gidey Brhane, Tsegahun Manyazewal, Hussien Mohammed, Yonas Wuletaw, Moges Kassa, Mesay Hailu, Getachew Tollera, Geremew Tasew, Ashenafi Assefa, Eyasu Makonnen

“…These findings support the ongoing use of AL with a single dose of PQ as the primary treatment option for uncomplicated P. falciparum infections in the study area. In the context of the emergence and spread of partial artemisinin-based combination therapy(ACT) resistance in Africa, regular monitoring of the efficacy of current artemisinin-based combinations is recommended for the early detection of emerging drug resistance in the study setting and beyond.…”
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Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
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Life expectancy by religious affiliation in Finland 1972–2020 by Julia Klein, Jan Saarela, Martin Kolk

“…Non-affiliated persons have about one-year shorter life expectancy than Evangelical Lutherans, but the difference has decreased over time, and they currently are at a similar level. …”
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Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique by Mohan K Thomas, James A Dsilva, Ateesh J Borole, Sudhir M Naik, Soma G Sarkar

“…Context: Facial fillers have revolutionized the field of cosmetic facial rejuvenation as it has become the prime sought - after rejuvenation procedure offering youthful, 3-dimensional look with minimal invasiveness. …”
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Impact of a Saline Soil Improvement Project on the Spatiotemporal Evolution of Groundwater Dynamic Field and Hydrodynamic Process Simulation in the Hetao Irrigation District by Yule Sun, Liping Wang, Zuting Liu, Yonglin Jia, Zhongyi Qu

“…This work investigated the spatiotemporal evolution patterns and influencing factors of the groundwater environment in the context of soil salinity–alkalinity improvement, as well as the impact of irrigation on the ionic characteristics of groundwater. …”
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Strategies for adaptation of Russian commercial banks to innovative technologies by O. S. Solenaya

“…The article discusses the strategies of the bank in the innovation sphere, which are important components of general development strategies, their content and the order of choice in the context of digitalization of the economy and global changes in the world banking system. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Thermal and radiative effects on unsteady MHD flow of Casson fluid past a rotating porous medium with variable mass diffusion by J. Prakash, A. Selvaraj, P. Ragupathi, Qasem M. Al-Mdallal, S. Saranya

“…From the above results it can be seen that there are applications of these findings in the industrial and environmental context for example during MHD flow and filtration processes.…”
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Job Satisfaction Analysis of Nurses, who Work in Neurology and Neurosurgery Units by Anna Rymkiewicz

“…Satisfaction, facing problems and motivation are currently strategic points to be analysed in terms of nurses’ work. …”
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Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
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Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies by O. B. Gordeeva, M. S. Karaseva, D. E. Lavretsky, M. A. Babaikina, N. D. Vashakmadze, M. A. Soloshenko, G. V. Revunenkov, E. A. Abashidze, M. V. Egorova

“…Thrombosis in children with genetically determined thrombophilia often occur in the context of risk factors. In the early neonatal period, the deficiency of anticoagulant factors manifests as the form of fulminant purpura, followed by the development of skin necrosis. …”
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Investigating the Relationship between Types of Deprivation and Social Tolerance among Citizens of Tehran by Negar Firouzeh, Khadijeh Safiri

“…This positive and significant relationship between political deprivation and social tolerance could be understood in the context of societal bipolarity and the widening gap between the state and its citizens. …”
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Evaluation of Total Electron Content Prediction Using Three Ionosphere‐Thermosphere Models by O. Verkhoglyadova, X. Meng, A. J. Mannucci, J.‐S. Shim, R. McGranaghan

“…The meanings of contingency table elements for the prediction performance are analyzed in the context of ionosphere modeling. Prediction success is between about 0.2 and 0.5 for weak ionospheric disturbances and decreases for strong disturbances. …”
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Characterization of the Power Distribution Network for Commercialized STM32s Using a Resonance Frequency Measurement Method by Marie Peyrard, Gilles Jacquemod, Nicolas Froidevaux

“…The present tendency of increasing current density and operating frequency, along with decreasing operating voltage, significantly diminishes voltage margins. …”
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