Characterization of a novel Leishmania antigen containing a repetitive domain and its potential use as a prophylactic and therapeutic vaccine by Bianca de Oliveira, Wanessa M. Goes, Frederico C. Nascimento, Juliana B. T. Carnielli, Eden R. Ferreira, Alex Fiorini de Carvalho, Pablo Victor Mendes dos Reis, Milton Pereira, Tiago Queiroga Nery Ricotta, Liliane Martins dos Santos, Renan Pedra de Souza, Diego Esteban Cargnelutti, Jeremy C. Mottram, Santuza R. Teixeira, Ana Paula Fernandes, Ricardo T. Gazzinelli

“…ABSTRACT Human visceral leishmaniasis (HVL) is the second most lethal tropical parasitic disease. Currently, no prophylactic or therapeutic vaccines exist for HVL. …”
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Effects of KCNQ2 gene truncation on M-type Kv7 potassium currents. by Jon Robbins, Gayle M Passmore, Fe C Abogadie, Joanne M Reilly, David A Brown

“…Measurements of tetraethylammonium block did not indicate an increased expression of Kv7.5-containing subunits, implying a compensatory increase in Kv7.2 expression from the remaining KCNQ2 gene. …”
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Hybrid hydrogels containing gradients in gold nanoparticles for localized delivery of mesenchymal stem cells and enhanced nerve tissues remodeling in vivo by Jie Gao, Yiduo Zhou, Gang Xu, Zhongqing Wei, Liucheng Ding, Wei Zhang, Yi Huang

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Machine learning application to predict binding affinity between peptide containing non-canonical amino acids and HLA-A0201. by Shan Jiang, Zhaoqian Su, Nathaniel Bloodworth, Yunchao Liu, Cristina E Martina, David G Harrison, Jens Meiler

“…However, such modifications are increasingly recognized as critical mediators of peptide immunogenicity. …”
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Formulation of Topical Drug Delivery Systems Containing a Fixed-Dose Isoniazid–Rifampicin Combination Using the Self-Emulsification Mechanism by Melissa van Deventer, Richard K. Haynes, Marius Brits, Joe M. Viljoen

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Numerical Simulation Study on the Air/Water Counter- current Flow Limitation in Nuclear Reactors by youssef morghi, Amir Zacarias Mesquita

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Current Research on Quantifying Cotton Yield Responses to Waterlogging Stress: Indicators and Yield Vulnerability by Long Qian, Yunying Luo, Kai Duan

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The current state and prospects for the development of the Ukrainian market of veterinary drugs for the treatment of skin diseases by I. V. Bushuieva, M. V. Ohloblina

“…The trend of increasing incidence of skin diseases of various etiologies and the frequency of complications caused by them (dermatitis, allergies, secondary infections, eczema, trichophytosis, dermatophytosis, dermatomycosis, etc.) is increasing in Ukraine. …”
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Numerical Simulation of Dispersion and Ventilation of Hydrogen Clouds in Case of Leakage Inside a Large-Scale Industrial Building by Khaled Yassin, Stephan Kelm, Ernst-Arndt Reinecke

“…Additionally, locating the exhaust outlets near the ceiling can decrease the combustible cloud volume by more than 25% compared to side openings far below the ceiling. …”
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Evaluating the Impact Performance of Environmentally Friendly Asphalt Concrete Slabs Containing Different Proportions of Recycled Concrete Aggregate and Corrugated Steel Fibers by Walid Mansour, Diaa Ashraf, Ali Basha

“…Abstract The current research focuses on recycling construction waste by producing asphalt concrete mixtures containing varying proportions of recycled concrete aggregate (RCA), ranging from 0 to 50%. …”
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Experimental and Mechanism Study on Axial Compressive Performance of Double Steel Tube Columns Filled with Recycled Concrete Containing Abandoned Brick Aggregate by Yuanyuan Sun, Dongxu Hou, Yanbiao Shi, Yamei Sun, Fancheng Meng, Dong Chen

“…The investigation indicated that, under the current conditions, the presence of the inner steel tube only increased the strength by 0.14%. …”
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Policy Formulations to Establish More Dry Port Infrastructures to Increase Seaport Efficiency, Productivity, and Competitiveness in Bangladesh by Razon Chandra Saha, Khairir Bin Khalil

“…In the findings, 82.50% of participants agreed that existing facilities are not enough and need to establish more dry ports to handle current and future volumes of containers. Moreover, the responses reveal a division of opinion on establishing a dry port outside of Chattogram, with a notable inclination towards opposition. …”
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Concurrent Chemoradiotherapy Increases the Levels of Soluble Immune Checkpoint Proteins in Patients with Locally Advanced Cervical Cancer by Chao Liu, Xiaohui Li, Aijie Li, Wenxue Zou, Rui Huang, Xiaoyu Hu, Jinming Yu, Xiaoling Zhang, Jinbo Yue

“…The levels of soluble T-cell immunoglobulin and mucin-domain containing-3 (sTIM-3) significantly increased during CCRT (P=0.041), while those of the soluble B and T lymphocyte attenuator (sBTLA), sCD40, soluble glucocorticoid-induced tumor necrosis factor receptor ligand (sGITRL), sCD80, sCD86, sPD-1, sPD-L1, sCTLA-4, and soluble inducible T-cell costimulator (sICOS) significantly increased after CCRT (all P<0.05). …”
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Current approaches to the use of antiplatelet and anticoagulant drugs in pregnant women with thrombocytopenia caused by hemostasis activation by O. L. Mysik, M. S. Zainulina

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Structure and Electrocatalytic Properties of Sulfur-Containing Multi-Walled Carbon Nanotubes on a Titanium Substrate Modified by a Helium Ion Beam by Petr M. Korusenko, Egor V. Knyazev, Alexander S. Vinogradov, Ksenia A. Kharisova, Sofya S. Filippova, Ulyana M. Rodionova, Oleg V. Levin, Elena V. Alekseeva

“…The results indicate that the ion beam treatment of the S-MWCNT system led to an increase in the level of imperfections on the surface structures of the nanotubes due to the formation of point defects on their outer walls and the appearance of oxygen-containing functional groups, including SO_x groups, near these defects. …”
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CAR-T cells containing CD28 versus 4-1BB co-stimulatory domains show distinct metabolic profiles in patients by Molly S. Cook, Ellen King, Katie R. Flaherty, Khadiza Siddika, Sophie Papa, Reuben Benjamin, Anna Schurich

“…The most common CAR-T cell products currently in the clinic for DLBCL differ in their co-stimulation moiety, containing either CD28 or 4-1BB, which initiate distinct signaling pathways. …”
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Holistic Dynamic Modeling and Simulation of Alkaline Water Electrolysis Systems Based on Heat Current Method by Yi-Chong Jiang, Shi-Meng Dong, Zheng Liang, Xiao-Li Wang, Lei Shi, Bing Yan, Tian Zhao

“…Hydrogen production technology is becoming increasingly important with the rapid development of hydrogen energy. …”
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Successive increases in the resistance of Drosophila to viral infection through a transposon insertion followed by a Duplication. by Michael M Magwire, Florian Bayer, Claire L Webster, Chuan Cao, Francis M Jiggins

“…This resistant allele has rapidly increased in frequency under directional selection and is now the commonest form of the gene in natural populations. …”
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Retrospective and current state of forest territories of the border areas of the Bryansk region exposed to radioactive contamination by T. A. Marchenko, A. I. Radin, A. N. Razdaivodin

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U-SCAD: An Unsupervised Method of System Call-Driven Anomaly Detection for Containerized Edge Clouds by Jiawei Ye, Ming Yan, Shenglin Wu, Jingxuan Tan, Jie Wu

“…Container technology is currently one of the mainstream technologies in the field of cloud computing, yet its adoption in resource-constrained, latency-sensitive edge environments introduces unique security challenges. …”
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