Nanostructured Strategies for Melanoma Treatment—Part I: Design and Optimization of Curcumin-Loaded Micelles for Enhanced Anticancer Activity by Valentina Paganini, Andrea Cesari, Silvia Tampucci, Patrizia Chetoni, Susi Burgalassi, Michele Lai, Giulia Sciandrone, Silvia Pizzimenti, Fabio Bellina, Daniela Monti

“…Additionally, free curcumin induced a 30% increase in cytoplasmic area, indicating necrosis, whereas TPGS30ELP15 decreased the cytoplasmic area by 20%, suggesting apoptosis. …”
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Heat Removal Performance Analysis of HTR-PM Reactor Cavity Cooling System under Accident Condition by QIN Haiqi, LI Xiaowei, ZHANG Li, LIU Xiongbin, ZHENG Yanhua, WU Xinxin

“…When the atmosphere temperature increases from 25 ℃ to 42 ℃, the maximum concrete temperature increases from 86 ℃ to 111 ℃. …”
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The Effects of Creatine Monohydrate and/or Whey Protein on the Muscle Protein Synthesis and Anabolic Signaling Responses in Non-Stressed C₂C₁₂ Murine Myotubes by Nicholas J. Kontos, Joshua S. Godwin, Anthony Agyin-Birikorang, Darren G. Candow, Christopher M. Lockwood, Michael D. Roberts, Christopher B. Mobley

“…<b>Conclusions</b>: WP increases protein synthesis and anabolic signaling with no additive effect from CRE. …”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…Those who were persistent smokers reported increasing respiratory symptoms. In contrast, the symptoms decreased among those who quit tobacco smoking, but there was no significant difference in respiratory symptoms between quitters with and without e-cigarette use. …”
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Development of a hydrogel-based three-dimensional (3D) glioblastoma cell lines culture as a model system for CD73 inhibitor response study by Marjan Bahraminasab, Samira Asgharzade, Ali Doostmohamadi, Atefeh Satari, Farkhonde Hasannejad, Samaneh Arab

“…GBM cells treated with CD73 inhibitors significantly decreased the proliferation rate and expression of VEGF and HIF1-α in the optimal hydrogel. …”
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Assessing Immunization Coverage and the Negative Impact of Local Vaccine Production Cessation in Ecuador by Esteban Ortiz-Prado, Lissette Carolina Villacreses-Brito, Jorge Vasconez-Gonzalez, Cristina Anabel Jacome, Marlon Arias-Intriago, Juan S. Izquierdo-Condoy

“…For BCG, median coverage decreased from 100% during the production period to 87.8% post-cessation (<i>p</i> < 0.0001). …”
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Investigating the Therapeutic Effects of Albendazole, Mebendazole, and Praziquantel Nanocapsules in Hydatid Cyst-Infected Mice by Nooshinmehr Soleymani, Soheil Sadr, Cinzia Santucciu, Abbas Rahdar, Giovanna Masala, Hassan Borji

“…Drug resistance is the main challenge in treating parasitic diseases, including cystic echinococcosis (CE). Hence, the current study aims to investigate the effect of nanocapsules containing albendazole (ABZ), mebendazole (MBZ), and praziquantel (PZQ) on treating hydatid cysts in mice using these high-potency drugs. …”
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Research on tetrahedral adaptive mesh grading refinement for intersecting faults by CHEN Yingxian, ZHU Zhe, MA Huiru, FU Jiepeng

“…Current tetrahedral adaptive mesh refinement techniques have primarily focused on the 3D reconstruction and analysis of simple stratified geological bodies. …”
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AI-based volumetric six-tissue body composition quantification from CT cardiac attenuation scans for mortality prediction: a multicentre study by Jirong Yi, PhD, Anna M Marcinkiewicz, MD, Aakash Shanbhag, MSc, Robert J H Miller, MD, Jolien Geers, MD, Wenhao Zhang, PhD, Aditya Killekar, MSc, Nipun Manral, MSc, Mark Lemley, BSc, Mikolaj Buchwald, PhD, Jacek Kwiecinski, MD, Jianhang Zhou, MSc, Paul B Kavanagh, MSc, Joanna X Liang, MPH, Valerie Builoff, BSc, ProfMD Terrence D Ruddy, BSc, ProfMD Andrew J Einstein, BSc, Attila Feher, MD, Edward J Miller, Prof, ProfMD Albert J Sinusas, Prof, ProfMD Daniel S Berman, Prof, ProfPhD Damini Dey, Prof, Piotr J Slomka, PhD

“…Summary: Background: CT attenuation correction (CTAC) scans are routinely obtained during cardiac perfusion imaging, but currently only used for attenuation correction and visual calcium estimation. …”
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New insights on physicochemical features and toxicological outcome provided from incineration of nanocomposites by Claire Longuet, Carine Chivas-Joly, Nora Lambeng, Valérie Forest, Lara Leclerc, Gwendoline Sarry, Jérémie Pourchez, José-Marie Lopez-Cuesta

“…A specific management of nanocomposites end-of-life should be implemented as recommended by the Organization for Economic Co-operation and Development (OECD) in order to limit nanoparticles dissemination by landfilling and particularly in incineration facilities where their presence is significantly increasing. The aim of our study was to expand the current knowledge of the partition of nanowaste, mainly in case of nanocomposites mixture, and the potential synergetic or antagonistic impact of potential hazardous nanowastes on the toxicological profile. …”
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The prevalence of obesity and overweight among Iranian population: an umbrella systematic review and meta-analysis by Azadeh Dehghani, Roghayeh Molani-Gol, Maryam Mohammadi-Narab, Abdolreza Norouzy, Mohammad Hassan Abolhassani, Seyed Mohammad Tabatabaee Jabali, Abdolreza Pazouki, Fahimeh Soheilipour, Fatemeh Mohammadi-Nasrabadi

“…The meta-analyses included in this study examined the prevalence of obesity and overweight in Iran. The current umbrella meta-analysis finally contained 24 meta-analyses. …”
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Development of a composite material based on a processed product of agricultural crop by Zura Yessimsiitova, Murat Toktar, Alibek Mutushev, Aizhan Konysbayeva, Gulmira Yeltay, Aliya Bagybekkyzy, Akmaral Kydyrkhanova, Damira Yussayeva

“…Anthropogenic influence on the environment contributes to an increase in the content of heavy metals in soils. This is facilitated by the developed industrial sector, high population density and large-scale growth of urban areas. …”
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A Comparison of the 𝜶2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain by Sarah Nickolls, Hannah Mace, Rebecca Fish, Michelle Edye, Rachel Gurrell, Magnus Ivarsson, Tom Pitcher, Sachi Tanimoto-Mori, Denise Richardson, Catherine Sweatman, Janet Nicholson, Cameron Ward, John Jinks, Christine Bell, Kimberly Young, Huw Rees, Andrew Moss, Ross Kinloch, Gordon McMurray

“…GABAA receptors containing α2/3 subunits are current targets in the battle to develop new pain medications, as they are expressed in the spinal cord where increasing inhibitory drive should result in analgesia. …”
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Monitoring Welfare of Individual Broiler Chickens Using Ultra-Wideband and Inertial Measurement Unit Wearables by Imad Khan, Daniel Peralta, Jaron Fontaine, Patricia Soster de Carvalho, Ana Martos Martinez-Caja, Gunther Antonissen, Frank Tuyttens, Eli De Poorter

“…Monitoring animal welfare on farms and in research settings is attracting increasing interest, both for ethical reasons and for improving productivity through the early detection of stress or diseases. …”
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Novel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement by Daniela Dellosso Cibim, Miki Taketomi Saito, Priscila Alves Giovani, Ana Flávia Sanches Borges, Vanessa Gallego Arias Pecorari, Orisson Ponce Gomes, Paulo Noronha Lisboa-Filho, Francisco Humberto Nociti-Junior, Regina Maria Puppin-Rontani, Kamila Rosamilia Kantovitz

“…Furthermore, regardless of TiO2 concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2 presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2 groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2 at 5%. …”
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Image-based honey bee larval viral and bacterial diagnosis using machine learning by Duan C. Copeland, Brendon M. Mott, Oliver L. Kortenkamp, Robert J. Erickson, Nathan O. Allen, Kirk E. Anderson

“…When tested on an independent dataset from Illinois containing additional viral pathogens not present in training data, the models showed higher accuracy for EFB (72–88%) than viral infections (28–68%), highlighting both the promise and current limitations of this approach. …”
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An explainable AI-driven deep neural network for accurate breast cancer detection from histopathological and ultrasound images by Md. Romzan Alom, Fahmid Al Farid, Muhammad Aminur Rahaman, Anichur Rahman, Tanoy Debnath, Abu Saleh Musa Miah, Sarina Mansor

“…While deep learning has demonstrated potential, many current models struggle with limited accuracy and lack of interpretability. …”
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High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations by Nobue Tamamura, Yoshihiko Hagiwara, Hirokazu Kato, Yusuke Ono, Kenji Takahashi, Kazuya Koyama, Hiroki Sato, Tetsuhiro Okada, Hidemasa Kawabata, Yu Ohtaki, Chiho Maeda, Miyuki Mori, Shin-ichi Chiba, Mishie Tanino, Kenzui Taniue, Takashi Anazawa, Ryoji Inaba, Yusuke Mizukami

“…Abstract Cancer genomics aims to personalize treatments by identifying genetic abnormalities in cancer cells. However, current analytical techniques face limitations in simplicity and cost-effectiveness. …”
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Pharmacological correction of hepatotoxicity induced by anti-tuberculosis drugs by D. S. Sukhanov, E. V. Timofeev, Y. S. Alekseeva, K. A. Nagornova

“…Hepatoprotective drugs of various origin and chemical composition are used for the correction and prevention of drug-induced liver injury. Currently, preparations of plant origin (from milk thistle, licorice, soy), animal origin, preparations of bile acids, and some others are isolated. …”
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Hybrid surface layers with antibacterial and anti-inflammatory activity for implants materials by Mariia A. Piatkova, Konstantine V. Nadaraia, Arina I. Ponomarenko, Igor V. Manzhulo, Mariia S. Gerasimenko, Arina I. Pleshkova, Evgeny A. Belov, Igor M. Imshinetskiy, Ksenia A. Fomenko, Ivan S. Osmushko, Aleksey G. Kozlov, Sergey V. Gnedenkov, Dmitry V. Mashtalyar

“…Currently, there is an essential need for bioresorbable bone implants with antibacterial, anti-inflammatory properties as well as osteoinductivity. …”
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