A New Human SCARB2 Knock-In Mouse Model for Studying Coxsackievirus A16 and Its Neurotoxicity by Haiting Wu, Ziou Wang, Yiwei Zhang, Lingfeng Hu, Jinling Yang, Caixing Zhang, Mumeng Lou, Na Pi, Qiyan Wang, Shengtao Fan, Zhangqiong Huang

“…Therefore, there is an urgent need for a more reliable and effective animal model to study CVA16. In this study, we successfully created a hSCARB2 KI mouse model targeting the ROSA26 locus using CRISPR/Cas9 gene editing technology. …”
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DEVELOPING YOUTH RESILIENCE IN CONDITIONS OF SOCIAL INSTABILITY AND WAR by Vira Syniakova, Yuliia Bokhonkova, Mykyta Minin

“…The aim of this study is to determine the psychological features of resilience formation among youth in conditions of social instability and military conflict, and to outline effective strategies for its development and support. …”
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HIIT versus MICT in MASLD: mechanisms mediated by gut-liver axis crosstalk, mitochondrial dynamics remodeling, and adipokine signaling attenuation by Dongkun Deng, Lin Xu, Yufei Liu, Chang Li, Qingfeng Jiang, Jiaming Shi, Shuo Feng, Yunhua Lin

“…It is noteworthy that HIIT was more effective in improving mitochondrial function in MASLD than MICT (P < 0.001). …”
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The Efficacy of Remineralizing Materials on Artificial Enamel Lesions: An In Vitro Study by Gustė Klimaitė, Arūnas Vasiliauskas, Pranas Grinkevičius, Dominyka Grinkevičienė, Deivydas Šapalas

“…While fluoride-based treatments remain the gold standard, their effectiveness has limitations, prompting interest in innovative remineralization technologies. …”
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Biosample collection in a biobank to solve problems of personalized medicine by O. V. Kopylova, A. I. Ershova, A. N. Meshkov, M. S. Pokrovskaya, I. A. Efimova, A. S. Limonova, A. V. Blokhina, Z. Z. Serebryanskaya, S. A. Smetnev, V. I. Mikhailina, R. P. Myasnikov, A. V. Kiseleva, E. V. Garbuzova, V. A. Metelskaya, A. L. Borisova, O. M. Drapkina

“…Preanalytical phase standardization creates the prerequisites for multicenter national and international cooperation.…”
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Physicochemical and Structural Properties of Freeze-Dried Lacto-Fermented Peach Snacks by Emilia Janiszewska-Turak, Szymon Ossowski, Zuzanna Domżalska, Klaudia Gregorek, Joanna Sękul, Katarzyna Pobiega, Katarzyna Rybak

“…Fermentation increased acidity (>22 mg/kg), decreased sugars (up to 43.5%), and raised salt content (to ~0.5%), effectively altering the fruit’s chemical profile. Dry matter content decreased by 6.0% (P_LP) and 7.2% (P_FF), while water activity remained low (0.13–0.15). …”
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Single-cell transcriptomics reveal the prognostic roles of epithelial and T cells and DNA methylation-based prognostic models in pancreatic cancer by Jing Du, Yaqian Zhao, Jie Dong, Peng Li, Yan Hu, Hailang Fan, Feifan Zhang, Lanlan Sun, Dake Zhang, Yuhua Zhang

“…Prognostic models based on DNAm markers of these cells effectively predicted patient survival, especially 5-year overall survival (AUC = 0.834). …”
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MRI-based deep learning and radiomics for predicting the efficacy of PD-1 inhibitor combined with induction chemotherapy in advanced nasopharyngeal carcinoma: A prospective cohort... by Yiru Wang, Fuli Chen, Zhechen Ouyang, Siyi He, Xinling Qin, Xian Liang, Weimei Huang, Rensheng Wang, Kai Hu

“…A prediction model was then created using these radiomic characteristics and DLFs to determine the effectiveness of PD-1 inhibitor combined with GP chemotherapy. …”
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Induced hepatocyte-like cells derived from adipose-derived stem cells alleviates liver injury in mice infected with Echinococcus Multilocularis by Hui Liu, Xiaojuan Bi, Ning Yang, Xue Zhang, Bingbing Fang, Nuerbaiti Kusuman, Wenmei Ma, Jing Li, Jin Chu, Li Sun, Liang Li, Guodong Lü, Renyong Lin

“…The expression of hepatocyte lineage markers was assessed and iHEPs function was evaluated by Periodic acid-Schiff staining. iHEPs were intravenously transplanted into mice infected with Echinococcus multilocularis. Histopathological analysis and liver function tests were used to assess therapeutic effects. …”
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Ultra-small defect-engineered UiO-66 on cellulose nanocrystal template for advanced carbon dioxide capture membrane by Xinyu Wang, Seyed Fatemeh Seyedpour, Sabahudin Hrapovic, Usha D. Hemraz, Mohammad Mozafari, Masoud Soroush, Muhammad Amirul Islam, Arash Mollahosseini, Mohtada Sadrzadeh, Jae-Young Cho

“…These results highlight the potential of CNC-UiO-66 hybrid membranes for efficient and cost-effective CCUS applications, particularly in flue gas treatment.…”
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Prognostic factors of disability progression in multiple sclerosis in real life: the OFSEP-high definition (OFSEP-HD) prospective cohort in France by Francis Guillemin, Jonathan Epstein, Pierre Labauge, Christine Lebrun-Frénay, Eric Thouvenot, Laurent Magy, Jerome De Sèze, Pierre Clavelou, Pierre Branger, Alain Créange, Elisabeth Maillart, Thibault Moreau, Hamza Achit, Bruno Stankoff, Emmanuelle Leray, Gilles Edan, Sandra Vukusic, Olivier Heinzlef, Aurélie Ruet, Yohann Foucher, Philippe Cabre, Olivier Casez, Guillaume Mathey, Jonathan Ciron, Eric Berger, Caroline Papeix, Helene Zephir, David Laplaud, Inès Doghri, Amélie Dos Santos, Romain Casey, Fabien Rollot

“…Purpose To determine prognostic factors of disability in multiple sclerosis (MS), that is, (1) identify determinants of the dynamics of disability progression; (2) study the effectiveness of disease-modifying treatments (DMTs); (3) merge determinants and DMTs for creating patient-centred prognostic tools and (4) conduct an economic analysis.Participants Individuals registered in the French Observatoire Français de la Sclérose en Plaques (OFSEP) database were included in this OFSEP-high definition cohort if they had a diagnosis of MS, were ≥15 years old and had an Expanded Disability Status Scale (EDSS) score &lt;7. …”
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Implementation of a Scalable Online Weight Management Programme in Clinical Settings: Protocol for the PROPS 2.0 Programme (Partnerships for Reducing Overweight and Obesity with Pa... by David Westfall Bates, Jason P Block, Lipika Samal, Ronen Rozenblum, Caroline M Apovian, Benjamin M Scirica, Heather J Baer, John E Orav, JoAnn Cho, Sarah H Noonan, Richard Fay, Ashley C McCarthy, Alexander J Blood, Naomi Fisher, Jorge Plutzky, Michela Tucci, Marian McPartlin, Willam J Gordon, Katherine D McManus, Cheryl Morrison-Deutsch

“…The RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework is guiding the evaluation.Ethics and dissemination The Mass General Brigham Human Research Committee approved this protocol. …”
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Ferroptosis mediated by the IDO1/Kyn/AhR pathway triggers acute thymic involution in sepsis by Zimei Cheng, Kexin Wang, Yixue Wang, Tingyan Liu, Jingjing Li, Yaodong Wang, Weiming Chen, Reyihangu Awuti, Hetian Zhou, Wenjia Tong, Zhenhao Yu, Yao Wang, Guoyun Su, Weiguo Yang, Yufeng Zhou, Guoping Lu, Caiyan Zhang

“…Treatment with 1-methyltryptophan (IDO1 inhibitor) effectively restore thymic function and improve survival in septic mice. …”
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Defining analytical skills for human resources analytics: A call for standardization by Konrad Kulikowski

“…Then, the gap analyses reveal that important analytical KSAs, such as knowledge of sales and marketing, skills in operations analysis, and abilities in mathematical and inductive reasoning, are not expected from HR occupations, creating serious barriers to HR analytics development. …”
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Willingness to pay for a new biopesticide to control mango fruit flies by Boureima Tassembédo, Mathieu Ouédraogo, Karim Nébié, Antonio Alain Coffi Sinzogan, Patrice Toé

“…Practical value / implications. To effectively control fruit flies, it is necessary for decision makers to work closely with the private sector to make the yeast waste-based biopesticide for fruit fly control affordable by creating incentives for its multiplication and distribution. …”
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Shifting sands: The influence of coral reefs on shoreline erosion from short-term storm protection to long-term disequilibrium by Stephan A Bitterwolf, Borja G Reguero, Curt D Storlazzi, Michael W Beck

“…While the flood protection benefits of reefs have been well-documented, their effects on shoreline erosion are comparatively less understood. …”
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Stress Management in the Modern Workplace and the Role of Human Resource Professionals by Cam T.H. Tran, Hieu T.M. Tran, Huy T.N. Nguyen, Dung N. Mach, Hung S.P. Phan, Bahaudin G. Mujtaba

“…According to the analysis of five interviews with experienced managers from Vietnamese companies, there are recommendations on how to form and implement stress management strategies for human resource managers. …”
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Genomic regions of Solanum tuberosum L. associated with the tuber eye depth by I. V. Totsky, I. V. Rozanova, A. D. Safonova, A. S. Batov, Yu. A. Gureeva, A. V. Kochetov, E. K. Khlestkina

“…It will be possible to screen the breeding material and to breed the varieties more effectively using current markers associated with a shallow tuber’s eye depth.…”
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Recognizing the dimensions and components of school social responsibility in order to achieve the appropriate mode by mahmood noori, kolsum nami, mahdi bagheri

“…Introduction School is one of the most effective spaces for education, promoting a culture of participation, and crystallization of students' personality and accountability. …”
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DNA Specimen Preservation Using DESS and DNA Extraction in Museum Collections by Eri Ogiso-Tanaka, Daisuke Shimada, Akito Ogawa, Genki Ishiyama, Ken-ichi Okumura, Kentaro Hosaka, Chikako Ishii, Kyung-Ok Nam, Masakazu Hoshino, Shuhei Nomura, Showtaro Kakizoe, Yasuhide Nakamura, Isao Nishiumi, Minako Abe Ito, Taiju Kitayama, Norio Tanaka, Tsuyoshi Hosoya, Utsugi Jinbo

“…This creates a pressing need to develop more widely applicable DNA preservation methods. …”
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