Novel homozygous frameshift mutation of ITGB3 in the Glanzmann thrombasthenia patient with abnormal bone metabolism and congenital bone defects by Yujiao Luo, Nina Guo, Yewei Wang, Ji Li

“…The expression levels of CD41 (αIIb) and CD61 (β3) on the platelet surface and total in platelet were detected by flow cytometry and Western blot. Bioinformatics analysis was used to evaluate the pathogenicity of mutation sites and their effects on protein structure and function. …”
Get full text

Piloting the Extension for Community Healthcare Outcomes (ECHO) Pediatric Oncology Telehealth Education Program in Western Kenya: Implementation Study by Tyler Severance, Gilbert Olbara, Festus Njuguna, Martha Kipng'etich, Sandra Lang'at, Maureen Kugo, Jesse Lemmen, Marjorie Treff, Patrick Loehrer, Terry Vik

“…ConclusionsThe Project ECHO platform created a dynamic virtual platform to continue to engage stakeholders across western Kenya. …”
Get full text

Integrated Optimization of Manufacturing and Reinforcement Parameters in Hybrid Reinforced Aluminum Matrix Composites through Multi-Response Research and Taguchi-Grey Relationship... by Chandrasekhar Rao Bandaru, Seshappa Angadi, Mounika Thati, Subbaratnam Bhavanasi, Prudhvi Raj Konka, Ganni Aditya

“…Hybrid electric vehicles (HEVs) become widely favored in the global mobility sector owing using their cost-effectiveness with superior energy efficiency in comparison to traditional components. …”
Get full text

Climatic Assessment of Walls Inspired by Hierarchical (Hereditary) Structures in Nature by Leila sadat Hamidian Divkolaei, Seyyedeh Mahsa Bagheri

“…Nature, as the mother of man and all creatures and a source full of ideas, technology and all tested phenomena, can be a stable source for creating ideas and modeling it for humans in order to reduce the effects of various crises. …”
Get full text

Successful Expression of DNA-Based Vaccine Construct Encoding Human Papillomavirus Type 16 E7 Fused to Heat Shock Protein B1 in Eukaryotic Cells by Reyhane Najafi1, Azam Bolhassani2*, Maryam Montazeri1, Elnaz Agi3

“…Introduction: Developing potent therapeutic vaccines against human papillomaviruses (HPVs) is crucial for the effective management of various HPV-associated cancers. …”
Get full text

Agent-Based Adaptive Dynamic Round Robin (AADRR) Scheduling Algorithm by Zafar Iqbal Khan, Muzafar Khan, Syed Nasir Mehmood Shah

“…Additionally, AADRR efficiently manages preemptable tasks, using dynamic scheduling policies to accommodate variations in process priority and CPU burst times, ensuring fair scheduling, efficient resource utilization, and dynamic adaptability. To validate the effectiveness of the AADRR algorithm, we performed a comparative performance analysis with twelve other algorithms, including five traditional CPU scheduling algorithms and seven advanced job scheduling techniques, demonstrating optimal performance results. …”
Get full text

Needs of the network: a qualitative study of the needs of family members, partners and close friends of people with a severe mental illness (SMI) by Gwen van Husen, Thijs J. Burger, Mariken B. de Koning, Matty A.S. de Wit, Menno W. Segeren, Aartjan T.F. Beekman

“…We used reflexive thematic analysis to analyze the data, resulting in three themes of perceived needs and useful support. …”
Get full text

The impacts of freeze-thaw cycles on polypropylene fiber-reinforced clayey soil stabilized with alkali-activated fly ash by Arash Rajaee, Nafiseh Talebi, Saeed Abrishami

“…While initial FTCs caused no mass loss, subsequent cycles led to increased mass loss and remained below 2 % for all samples. Microstructural analysis results corroborated UCS test results. Although the primary chemical composition remained unchanged after 12 FTCs, these cycles induced morphological changes such as critical void formation and cracking within the gel structure. …”
Get full text

Studying the Behavior of Avoiding Cultural and Social Information of Students and Presenting a Model by Mohsen Shirazi Mehrabad, Afshin Mousavi Chelak, Maryam Salami, Soraya Ziaei

“…And favoring intellectual and intellectual information and disfavoring instinctive information, helping comprehensive growth and preventing one-dimensional growth and development of students, increasing comprehensive analysis of the state of oneself and the country, cultural and social development of students, cultural self-confidence and lack of orientation towards culture It was alien to the strategies resulting from this interview.Conclusion: Considering the impact of cultural and social information on the growth and development of students and the prevalence of information avoidance behavior among students, by knowing this behavior and coping strategies, the harms and negative effects of this behavior can be created with factors such as explaining the value of cultural information. …”
Get full text

Reporting Digital Health Implementations Based on the iCHECK-DH Guidelines and Checklist: Development of an Interactive Toolkit by Anuradha Liyanage, Shakira Irfaan, Loshan Moonesinghe, Kaushalya Kasturiaratchi, Caroline Perrin Franck, Rada Hussein

“…MethodsThe iCHECK-DH toolkit was developed through an iterative process informed by best practices for creating user-friendly toolkits. A targeted literature review and analysis of World Health Organization documents were conducted to identify best practices in toolkit design. …”
Get full text

Improving the technology of pate products by using additives from non-traditional raw materials of plant origin by Y. Matsuk, A. Geredchuk, I. Bleskov

“…The study confirmed the ecological effectiveness of the proposed approach, as utilizing plant-based waste materials reduces food losses and minimizes environmental impact. …”
Get full text

Prediction model of axillary lymph node status using an automated breast volume ultrasound radiomics nomogram in early breast cancer with negative axillary ultrasound by Qianqing Ma, Qianqing Ma, Junli Wang, Zhengzheng Tu, Jingwen She, Jianhui Zhu, Feng Jiang, Chaoxue Zhang

“…Using unsupervised cluster analysis, intratumoral and peritumoral 5mm were classified into 3 habitats, and they differed in PR and Her-2 expression. …”
Get full text

Exploring nurse and patient perspectives on WeChat-based prenatal education in Chinese public hospitals: a qualitative inquiry by Yushi He, Guangmei Fan, Guangrui Fan, Dandan Liu

“…Data were analyzed using thematic analysis to identify commonalities and divergences between nurse-driven and patient-driven experiences. …”
Get full text

Toward Interoperable Digital Medication Records on Fast Healthcare Interoperability Resources: Development and Technical Validation of a Minimal Core Dataset by Eduardo Salgado-Baez, Raphael Heidepriem, Renate Delucchi Danhier, Eugenia Rinaldi, Vishnu Ravi, Akira-Sebastian Poncette, Iris Dahlhaus, Daniel Fürstenau, Felix Balzer, Sylvia Thun, Julian Sass

“…The lack of interoperable medication data within and across hospitals not only creates an administrative burden through redundant data entry but also increases the risk of errors due to human mistakes, imprecise data transformations, and misinterpretations. …”
Get full text

Evaluation of high school-based dengue solution model in Southern Thailand: a community participatory action research by Charuai Suwanbamrung, Sandeep Kumar Mehraj, Melkamu Worku Kercho, Muhammad Haroon Stanikzai, Temesgen Anjulo Ageru, Jiraporn Jaroenpool, Panatda Pibul, Shamarina Shohaimi, Eskinder Israel

“…Abstract Introduction By the time the globe started to tackle the COVID-19 pandemic, Southeast Asian countries had faced an increased dengue incidence, which has eventually become an important public health problem. However, effective and sustainable disease control measures in the area are still lacking. …”
Get full text

Study on scientific productivity determination and scientific productivity improvement of rock burst mine by Feng CUI, Zhong LUO, Xingping LAI, Jianqiang CHEN, Baoshan PENG, Lei ZOU, Xudong LIU

“…The top-level design of productivity improvement in rock burst mine is constructed, and it is clearly pointed out that the key to control productivity is the impact risk brought by productivity improvement, so as to achieve the balance between mining intensity and unloading pressure and reduce the impact risk, thus effectively improving productivity. The integrated technical path from scientific planning of mine field scope and scientific design of coal face to scientific determination and improvement of productivity in rock burst mine is constructed, which provides scientific guidance for scientific determination and improvement of productivity in rock burst mine.…”
Get full text

Assessment of caregiving burden among caregivers of older adults with stroke in Saudi Arabia: analytical cross-sectional study by Ala’a Alahmadi, Sami A R Al-Dubai, Rana A. Alhelali, Hamadi A. Alrefaei, Nader M. Alqerafi

“…Consider them an integral part of the care team, as their unpaid caregiving helps improve the efficiency and effectiveness of care.…”
Get full text

What can be learned from the impact of the COVID-19 crisis on work participation among people with work disabilities? A qualitative practice & policy perspective approach by Mara de Visser, Trees Juurlink, Astrid Bosma, Marloes Zijl, Johannes R. Anema, Maaike A. Huysmans

“…Job loss and detrimental effects on mental health were identified. Other barriers to work participation included hampered collaboration between stakeholders during lockdowns and fewer job opportunities due to workplace shutdowns. …”
Get full text

CrossFit^® and Its Influence on Health Behaviors, Functional Capacity, and Psychosocial Outcomes: An Explorative Study of Gender Differences in Athlete Perspectives by Alessandra Amato, Luca Petrigna, Leonardo Di Gregorio, Giuseppe Musumeci

“…<b>Methods</b>: A total of 202 participants (age 34.3 ± 10.0 years) with at least 6 months of CrossFit^® experience completed an online self-reported questionnaire not previously published but created following published guidelines. The questions explore athletes’ perceptions of their improvements in physical fitness, injury occurrence, and the effects on mental well-being. …”
Get full text

Cancer-associated fibroblasts gene signature: a novel approach to survival prediction and immunotherapy guidance in colon cancer by Wenbing Zhang, Chi Yang, Ye Lu, Ye Lu, Chenling Tang, Mengyu Zhao, Zhaohui Wang, Jidong Gao, Jidong Gao, Shuangjiu Hu, Zhihua Chen

“…Ultimately, we verified MAN1B1 expression and function through in vitro assays.ResultsRelying on the bulk RNA-seq and scRNA-seq data study, we created a predictive profile with 11 CAFGs. The profile effectively differentiated survival differences among cohorts of colon adenocarcinoma patients. …”
Get full text