Healthcare collapse and disease spread: a qualitative study of challenges in Gaza strip by Samer Abuzerr, Kate Zinszer, Hussam Mahmoud

“…The semi-structured interview guide used in this study was specifically developed by the research team to address the study’s objectives. …”
Get full text

Exploring pre-service teachers’ generative AI readiness and behavioral intentions by Phuong Bui, Tiina Korhonen, Sini Kontkanen, Sorella Karme, Satu Piispa-Hakala, Marjaana Veermans

“…This study underscores the importance of developing GenAI competencies among pre-service teachers to ensure effective, responsible, and pedagogically meaningful AI adoption. …”
Get full text

Improving Surgical Site Infection Prediction Using Machine Learning: Addressing Challenges of Highly Imbalanced Data by Salha Al-Ahmari, Farrukh Nadeem

“…<b>Methods</b>: Using routine SSI surveillance data from multiple hospitals in Saudi Arabia, we analyzed a dataset of 64,793 surgical patients, of whom 1632 developed SSI. Seven machine learning algorithms were created and tested: Decision Tree (DT), Gaussian Naive Bayes (GNB), Support Vector Machine (SVM), Logistic Regression (LR), Random Forest (RF), Stochastic Gradient Boosting (SGB), and K-Nearest Neighbors (KNN). …”
Get full text

In-hospital mortality for aspiration pneumonia in a tertiary teaching hospital: A retrospective cohort review from 2008 to 2018 by Dongho Shin, Gerald Lebovic, R. Jun Lin

“…Conclusion Elderly patients are a high-risk population for developing aspiration pneumonia and are at higher risk of death when hospitalized for this condition. …”
Get full text

Structure-based design of a single-chain triple-disulfide-stabilized fusion-glycoprotein trimer that elicits high-titer neutralizing responses against human metapneumovirus. by Li Ou, Steven J Chen, I-Ting Teng, Lijuan Yang, Baoshan Zhang, Tongqing Zhou, Andrea Biju, Cheng Cheng, Wing-Pui Kong, Nicholas C Morano, Erik-Stephane D Stancofski, John-Paul Todd, Yaroslav Tsybovsky, Shuishu Wang, Cheng-Yan Zheng, John R Mascola, Lawrence Shapiro, Ruth A Woodward, Ursula J Buchholz, Peter D Kwong

“…While promising subunit vaccines are being developed with prefusion-stabilized forms of the fusion glycoproteins (Fs) of RSV and PIVs, for which neutralizing titers elicited by the prefusion (pre-F) conformation of F are much higher than for the postfusion (post-F) conformation, with HMPV, pre-F and post-F immunogens described thus far elicit similar neutralizing responses, and it has been unclear which conformation, pre-F or post-F, would be the most effective HMPV F-vaccine immunogen. …”
Get full text

Assessment of the Impact of Floods to the Local Community in Nyarusiza Sub-County Kisoro District. by Murengezi, Innocent

“…The study investigated the impact of floods on the local communities and developed policy options not only to mitigate flooding in communities of Kisoro District but also Uganda at large Nyarusiza Sub-county, Kisoro District. …”
Get full text

Clinical application values of a novel synthetic training simulator for bulbar urethral anastomosis by Jing‐Dong Xue, Ping Zhang, Yue‐Min Xu, Ying‐Long Sa, Hui‐Quan Shu, Lin Wang, Hong Xie, Chao Li, Wei Zhang, Chao Feng, Deng‐Long Wu

“…Abstract Purpose This study aimed to report a newly developed, high‐fidelity synthetic simulator to simulate excision and primary anastomotic (EPA) bulbar urethroplasty and its clinical use for new practitioners in shortening the learning curve. …”
Get full text

How to Enhance the Future of Urban Environments Through Smart Sustainable Urban Infrastructures? by Mazin Al-Saffar, Afrah Bathsha, Ching-Hsing Chang, Hui Ge, Xiaowen Huang, Kaiwen Shi, Yan Lu, Zhiyuan Peng, Wenyan Sun, Heying Wang, Ruoying Wang, Wei Zhou, Zhujun Ye, Mengxue Yu, Zhujun Zha, Xiaoyu Bao, Kaixiang Zhou

“…Leaders, governments, architects, urban designers, developers, planners and business leaders need to make decisions and find solutions for how billions of urbanites will live in the future. …”
Get full text

Lived experiences of adults living With HIV/AIDS receiving antiretroviral therapy at werabe comprehensive specialized hospital in Silte zone, Ethiopia by Abdulmejid Mustefa, Lonsako Abute, Kemal Lemnuro, Abdulkerim Badgeba, Delwana Bedru, Bisrat Feleke Bubamo, Gizachew Beykaso, Feleke Doyore Agide, Abinet Arega Sadore

“…Examining adult PLWHA experiences from various angles helps find gaps, develop plans, and put policies and coping mechanisms in place. …”
Get full text

The Geographical Distribution of Global Biobanks by Farzad Parvizpour, Sarvenaz Salahi, Mohammad Amin Mahmanzar, Karim Rahimian, Neda Esfandiari, Zahra Fatahi, Niousha Khoshdast, Reyhaneh Yarmohammadi, Mohamad Amir Amirkhani, Arefeh Jafarian

“…The protocolfor this review consisted of the following steps: i. Developing a search strategy to identify biobanks from each continent,ii. …”
Get full text

Opportunity for health and wellbeing co-benefits of climate adaptation policies and programs: a Delphi study in the Australian Capital Territory by A Lal, Z A Becvarik, Tomoko Sugiura, Daniel Miller, T Tsheten, L V White, E I Walsh, A Richardson

“…Future research needs to develop a standardised methodology to measure co-benefits that incorporates indicators considered most relevant and important by experts, with the prioritisation of co-benefits in this Delphi study providing a guide for research and evaluation in other contexts beyond the ACT.…”
Get full text

Evaluating educational effectiveness of three-dimensional (3D)-printed training models and custom-made fibula model for osteotomy and flap inset training in head and neck reconstru... by Dharmik Gondalia, Mohit Parakh, Kunal Mokhale, Vineet Kumar, Ameya Bindu, Mayur Mantri, Saumya Mathews, Dushyant Jaiswal, Akshay Bhavke, Vinay Kant Shankhdhar

“…Conclusion Low-cost 3D-printed training models and custom-made fibula models represent an effective and reproducible training tool for developing technical skills in head and neck reconstructive surgery. …”
Get full text

Identifying practices of information transfer between the hospital and primary care for older adults: a scoping review protocol by Philippe Desmarais, Claire Godard-Sebillotte, Thomas Tannou, Emily G. McDonald, Dounia Rouabhia, Géraldine Layani, Dimitri Yang, Martina Alkot, Andrea Quaiattini, Sabrina Lessard, Aigul Zaripova, Carolyn Pavoni, Sandrine Couture, Yu Qing Huang, Catherine Richer, Julia Chabot, Felix Pageau, Matthieu Calafiore, Karin Fink, Gulin Yilmaz, Beuscart Jean-Baptiste

“…We will use a search strategy developed with a specialised librarian to search four databases (MEDLINE, Embase, CINAHL and AgeLine) and reference lists of selected studies. …”
Get full text

Deterministic Fabrication of Fluorescent Nanostructures Featuring Distinct Optical Transitions by Marijn Rikers, Ayesheh Bashiri, Ángela Barreda, Michael Steinert, Duk-Yong Choi, Thomas Pertsch, Isabelle Staude

“…While various methods were already developed for creating localized emitters, in this work we present a new method for the deterministic fabrication of fluorescent nanostructures featuring well-defined optical transitions; it works with a minimal amount of steps and is scalable. …”
Get full text

Biomineralized engineered Lactococcus lactis-based in situ vaccination enhances antitumor immunity via sequential activation of chemo-immunotherapy by Yan Wang, Qin Liu, Baorui Liu, Jie Shao, Junmeng Zhu, Rutian Li, Ziqi Chen, Yaohua Ke, Lanqi Cen, Wenmei Rao, Sen Hong, Yanhong Chu, Xiaoping Qian

“…An efficient co-delivery system to optimize chemo-immunotherapy is urgently needed.Methods We have previously developed an engineered Lactococcus lactis (FOLactis) expressing Flt3L and OX40L to activate immune cells. …”
Get full text

Dissecting the link between PD-1/PD-L1-based immunotherapy and cancer pain: mechanisms, research implications, and artificial intelligence perspectives by Marco Cascella, Brigida Miranda, Carmen Gagliardi, Lucia Santaniello, Milena Mottola, Alida Mancusi, Laura Ferrara, Federica Monaco, Francesca Gargano, Francesco Perri, Alessandro Ottaiano, Maurizio Capuozzo, Ornella Piazza, Stefano Pepe, Anna Crispo, Agostino Guida, Giovanni Salzano, Giustino Varrassi, Luigi Liguori, Francesco Sabbatino, The TRIAL Group

“…Understanding these mechanisms is crucial for developing future research directions in order to optimize pain management strategies in cancer patients. …”
Get full text

EIF2AK2 protein targeted activation of AIM2-mediated PANoptosis promotes sepsis-induced acute kidney injury by Siwei Wei, Lei Wu, Zhen Xiang, Xiaoxiao Yang, Dongjie Pei, Liubing Jiang, Zhen Du

“…Here, we evaluated the role of absent in melanoma 2 (AIM2) and eukaryotic translation initiation factor 2 alpha kinase 2 (EIF2AK2) in septic AKI.Methods A septic AKI model was created through cecal ligation and puncture (CLP), while an in vitro model was developed using lipopolysaccharide (LPS)-stimulated HK2 cells. …”
Get full text

Matrix Corrected SIMS In Situ Oxygen Isotope Analyses of Marine Shell Aragonite for High Resolution Seawater Temperature Reconstructions by Oliver M. Medd, Laura M. Otter, Ian S. Williams, Richard A. Stern, Michael W. Förster, Stephen M. Eggins, Laura Rodriguez‐Sanz, Nerilie J. Abram, Miaohong He, Michael J. Ellwood, Jessica A. Hargreaves, Stewart J. Fallon, Brett M. Knowles

“…Abstract Marine shells incorporate oxygen isotope signatures during growth, creating valuable records of seawater temperature and marine oxygen isotopic compositions. …”
Get full text

Digitally deployed, GP remote consultation video intervention that aims to reduce opioid prescribing in primary care: protocol for a mixed-methods evaluation by Nick Hex, Christopher Price, Yu Fu, Ben Allen, Tracy Finch, Denis Martin, Cormac G Ryan, Alan M Batterham, Niki Jones, Ewan Maule

“…A pilot intervention using smartphone video messaging has been developed to remotely explain the rationale for opioid reduction and facilitate self-initiation of support. …”
Get full text

Test-retest reliability of FreeSurfer-derived volume, area and cortical thickness from MPRAGE and MP2RAGE brain MRI images by Graham N. Knussmann, Jeffrey S. Anderson, Molly B.D. Prigge, Douglas C. Dean, III, Nicholas Lange, Erin D. Bigler, Andrew L. Alexander, Janet E. Lainhart, Brandon A. Zielinski, Jace B. King

“…Background and purpose: Large MRI studies often pool data gathered from widely varying imaging sequences. Pooled data creates a potential source of variation in structural analyses which may cause misinterpretation of findings. …”
Get full text