Exploring in silico drug design and pharmacokinetics study for identification of potent antidepressant agents by Sabitu Babatunde Olasupo, Adamu Uzairu, Gideon Shallangwa, Sani Uba

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Modeling and predicting individual variation in COVID-19 vaccine-elicited antibody response in the general population. by Naotoshi Nakamura, Yurie Kobashi, Kwang Su Kim, Hyeongki Park, Yuta Tani, Yuzo Shimazu, Tianchen Zhao, Yoshitaka Nishikawa, Fumiya Omata, Moe Kawashima, Makoto Yoshida, Toshiki Abe, Yoshika Saito, Yuki Senoo, Saori Nonaka, Morihito Takita, Chika Yamamoto, Takeshi Kawamura, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Yong Dam Jeong, Daiki Tatematsu, Marwa Akao, Yoshitaka Sato, Shoya Iwanami, Yasuhisa Fujita, Masatoshi Wakui, Kazuyuki Aihara, Tatsuhiko Kodama, Kenji Shibuya, Shingo Iwami, Masaharu Tsubokura

“…As we learned during the COVID-19 pandemic, vaccines are one of the most important tools in infectious disease control. To date, an unprecedentedly large volume of high-quality data on COVID-19 vaccinations have been accumulated. …”
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Valorization of bourbon stillage through production of tunable pure mycelium materials by Keya Rani Roy, Zachary Byrd, Michael P. Sama, Tyler J. Barzee

“…Other fungal phyla such as Mucoromycota offer benefits of faster growth, but suppression of sporulation is often more difficult. The production of PMM is a relatively new area and sufficient quantitative data is lacking on the effective cultivation and processing steps required to optimize the materials for different potential applications. …”
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Efficacy evaluation of allergen-specific immunotherapy in children with asthma: a systematic review and meta-analysis by Kangping Wu, Suling Wu, Lina Wang

“…Conclusion Allergen-specific immunotherapy showed a positive effect in improving the symptoms of childhood asthma and reducing the need for medication, but there was significant heterogeneity among different studies. More high-quality RCTs are needed in the future to further explore the safety and long-term efficacy of immunotherapy to optimize its application in the management of childhood asthma.…”
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Uncertainty Quantification and Assimilation Method Based on Evaluated Nuclear Data Sampling Method by HUANG Yihan, ZU Tiejun, LIU Zhengming, CAO Liangzhi, WU Hongchun

“…The sampling method developed based on evaluated nuclear data aims to more accurately quantify uncertainties and adjust prior nuclear data using measurement results and calculation uncertainties. …”

Research on Lightweight Dynamic Security Protocol for Intelligent In-Vehicle CAN Bus by Yuanhao Wang, Yinan Xu, Zhiquan Liu, Suya Liu, Yujing Wu

“…With the integration of an increasing number of outward-facing components in intelligent and connected vehicles, the open controller area network (CAN) bus environment faces increasingly severe security threats. …”
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Identification of relevant analytical methods for adeno-associated virus stability assessment during formulation development by Carina Rodenstein, Eva Schmid, Natalia Markova, Andreas Seidl

“…As functionality assays, such as reporter gene assays, are already established for rapid quality control assessments, they are not addressed in this study. …”
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Synergistic enhancement of recycled aggregate concrete using hybrid natural-synthetic fiber reinforcement and silica fume by Danish Akbar, Faisal Shabbir, Ali Raza, Nabil Ben Kahla

“…SEM images revealed denser interfacial transition zones (ITZ) and a more compact microstructure, attributed to the pozzolanic activity of silica fume and the effective crack-bridging behavior of the fibers. …”
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Coverage and contextual factors associated with insecticide-treated net use among women of reproductive age in Nigeria: evidence from the 2021 malaria indicator survey data. by Amadou Barrow, Oluwakemi Christie Ogidan, Chimezie Igwegbe Nzoputam, Michael Ekholuenetale

“…Although insecticide-treated nets (ITNs) are essential interventions for preventing malaria, their use in Nigeria is still sub-optimal. Understanding the factors influencing ITN use is essential to improve malaria control strategies. …”
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Joint formation mechanism and mechanical properties of laser brazed Zn coated steel under different defocusing conditions by Xiaoye Zhao, Hanwen Yang, Adrian Gerlich, Y. Norman Zhou

“…Laser brazing, producing a class-A joint surface in automotive, relies on the defocus control to manage laser heating mode and braze performance. …”
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About the creation of sterile lines of sweet pepper in breeding for heterosis by S. V. Koroleva, N. V. Polyakova, O. G. Pistun

“…Based on the results obtained, it is advisable to identify the breeding material for the Rf gene in the ACC, since the proposed growing regime serves as a provocative background and allows for more effective control over the manifestation of sterility.…”
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The effect of 8-week combined balance and plyometric training on change of direction performance of young badminton players by Cheng Guo, Mian Xu

“…The BP regimen proved more effective than the PL in improving dynamic balance, neuromuscular control, and stability, suggesting that integrating balance training with plyometric exercises is superior for optimizing performance and preventing injuries in this athletic population.…”
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Influence of soil phosphorus fertilizer forms on phosphorus uptake, morphology, and growth of leafy vegetables by Godfrey Nakitare Nambafu, Nicolai Hoeppner, Holger Bessler, Joseph Patrick Gweyi-Onyango, Darius O. Andika, Samuel Mwonga, Christof Engels

“…Spider plants absorbed high levels of P from all the P treatments, but could not convert more of it to biomass formation. African nightshade performed well in KH2PO4 and Phytate, but poorly in the rock P and FePO4. …”
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ACE inhibitor spirapril effects on circadian blood pressure profile, quality of life, and psychological status in patients with Stage I-II arterial hypertension by V. M. Gorbunov, M. I. Smirnova, G. F. Andreeva, A. D. Deev

“…Spirapril also improved socialisation, self-control, optimism, and general energy level.Conclusion. …”
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Real-World Experience with Carbidopa-Levodopa Extended-Release Capsules (Rytary®): Results of a Nationwide Dose Conversion Survey by Robert A. Hauser, Ghazal Banisadr, Kara Vuong, David Freilich, Stanley Fisher, Richard D’Souza

“…The dose conversion table in the CD-LD ER prescribing information was similar to the table used in the pivotal clinical trial and is considered by many prescribing HCPs to be less than optimal. By the end of the dose conversion period in that trial, dosing in 76% of subjects was adjusted for symptom control; roughly 60% of patients required a higher dose and about half required more frequent administration than the recommended TID dosing. …”
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Advances in Therapy for Urothelial and Non-Urothelial Subtype Histologies of Advanced Bladder Cancer: From Etiology to Current Development by Whi-An Kwon, Ho Kyung Seo, Geehyun Song, Min-Kyung Lee, Weon Seo Park

“…For localized disease, curative options such as surgical resection or radiotherapy are available; however, treatment options become more limited in recurrence or metastasis, where systemic therapy is primarily used to control disease progression and palliate symptoms. …”
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Exploring secular trends and types of tuberculosis burden in India over past three decades through insights from the Global Burden of Disease Study 2019 by Krittika Bhattacharyya, Ravi Prakash Jha, Deepak Dhamnetiya, Priyanka Patel, Neha Shri, Mayank Singh

“…AMR complicates TB management by limiting the efficacy of existing drugs, making it even more critical to address resistant strains with innovative solutions. …”
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Study on the Analgesic Efficacy of Femoral Nerve Block for Post-Hip Arthroscopy Pain by Mengwen Xue, Li Zhang, Ruiping Bai, Rui An, Jiarui Li, Xin Shen

“…Therefore, we designed this study to investigate the analgesic efficacy and optimal drug concentrations of FNB after hip arthroscopy. …”
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SINGLE STEP IMPLANTATION OF AN ARTIFICIAL SPHINCTER OF THE BLADDER AND PENILE PROSTHESIS AS A METHOD OF CORRECTING OF ERECTILE DYSFUNCTION AND URINARY INCONTINENCE by P. S. Kyzlasov, M. M. Sokol’shchik, N. A. Goncharov, S. V. Porowski, V. P. Sergeev, D. I. Volodin, A. A. Kisileva, M. V. Zabelin

“…Artificial sphincter allows you to fully control the process of retention of urine and urination. …”
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Clinical study of short-term spinal cord stimulation for herpes zoster-associated pain by Lei Zuo, Ai Su, YaChen Xie, XiaoQiu Yang

“…Conclusions Short-term spinal cord stimulation is a safe and effective short-term treatment for HZAP, offering faster and more effective pain relief and quality of life improvement compared to nerve block therapy. …”
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