Impact of Hypoalbuminemia on Outcomes Following Hepatic Resection: A NSQIP Retrospective Cohort Analysis of 26,394 Patients by Dunavan Morris-Janzen, Sukhdeep Jatana, Kevin Verhoeff, A. M. James Shapiro, David L. Bigam, Khaled Dajani, Blaire Anderson

“…Multivariable logistic regression models were used to assess the independent effect of HA on various outcomes. …”
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Efficacy of TIPS plus extrahepatic collateral embolisation in real-world data: a validation study by Chao Chen, Feng Zhang, Hao Wu, Wei Wu, Hui Xue, Yuzheng Zhuge, Chunqing Zhang, Guangchuan Wang, Zhengjie Li, Qiong Wu, Bo Wei, Jun Tie, Xiubin Sun, Lianhui Zhao, Yifu Xia, Jiao Xu, Peijie Li

“…Controlling post-TIPS portal pressure gradient (pPPG) within 7 mm Hg<pPPG<8.5 mm Hg improved prognosis, especially in TIPS+E group.Conclusion Our real-world data validation confirms the high efficacy of TIPS+E in reducing rebleeding and HE, particularly when using 8 mm diameter stents, embolising GV+SPSS and maintaining an optimal pPPG.…”
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Antibiotic stewardship in hematological patients with Escherichia coli and Klebsiella pneumoniae bloodstream infections: evaluating short-course and carbapenem-sparing strategies by Yuqing Cui, Xiaomeng Feng, Ling Pan, Qingsong Lin, Jieru Wang, Sisi Zhen, Yuping Fan, Xin Chen, Yizhou Zheng, Yingchang Mi, Fengkui Zhang, Xiaofan Zhu, Zhijian Xiao, Erlie Jiang, Mingzhe Han, Jianxiang Wang, Sizhou Feng

“…Propensity score matching (PSM) controlled for confounding variables, and data were analyzed using multivariate regression models. …”
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A novel tetrahedral framework nucleic acid-based antibiotic delivery system: overcoming biofilm barriers to combat chronic infections by Yue Hu, Zhou Chen, Xinggang Mao, Di Qu, Dongsheng Zhai, Na Li, Shan Zhou, Xiaoyan Xue, Mingkai Li

“…PMB@Td outperformed conventional liposome-encapsulated PMB (PMB@Lipo), achieving half-maximal biofilm eradication concentrations (MBEC50) of 12.8 µM versus 16.3 µM for PMB@Lipo. In murine models of biofilm- associated skin and pulmonary infections, PMB@Td effectively controlled bacterial burden and mitigated inflammatory responses without observable toxicity. …”
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Belief in building a full-fledged distance learning course in athletic training by Andrii Yefremenko, Illia Shutieiev

“…They are presented as three main blocks: theoretical, practical and controlling. An algorithm for organising practical training in athletic training has been formed. …”
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Innovative treatment of toxic oily petroleum wastewater with magnetic sludge under UVA light by Saeedeh Rastgar, Habibollah Younesi, Hassan Rezeai, Hajar Abyar

“…Kinetic and isotherm studies further elucidated the behavior of the photocatalytic process, revealing that the removal of toxic oily wastewater with Char/Fe3O4/TiO2 adhered closely to pseudo-first-order kinetic models, as well as the Freundlich and Henderson isotherm models. …”
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Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation by Chunxiang Lu, Aoxiang Jin, Chuang Gao, Hao Qiao, Huazhen Liu, Yi Zhang, Wenbin Sun, Shih-Mo Yang, Yuanyuan Liu

“…Compared to traditional methods, our proposed strategy enables high-throughput production of size-controlled spheroids with excellent shape retention, while enhanced gas exchange during culture improves differentiation marker expression. …”
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Synergistic behavioral and neuroplastic effects of psilocybin-NMDAR modulator administration by Tom Ben-Tal, Ilana Pogodin, Alexander Botvinnik, Tzuri Lifschytz, Uriel Heresco-Levy, Bernard Lerer

“…These findings support the hypothesis that combinations of SP with NMDAR modulators could optimize the therapeutic potential of SP by mitigating adverse effects and enhancing neuroplasticity. …”
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Optically tunable catalytic cancer therapy using enzyme-like chiral plasmonic nanoparticles by Haeun Kang, Subin Yu, Ryeong Myeong Kim, Youngbi Kim, Sang Chul Shin, Dohyub Jang, Jeong Hyun Han, Sugyeong Hong, Eunice EunKyeong Kim, Sun Hee Kim, Dong June Ahn, Jeong Woo Han, Sehoon Kim, Ki Tae Nam, Luke P. Lee, Dong Ha Kim

“…By sequentially activating GOD and POD reactions with right-handed CPL (RC) followed by left-handed CPL (LC), we achieve 1.25- and 1.9-fold enhanced catalytic performance (overall 1.3 times enhancement) compared to non-controlled cascade reactions by creating an optimal acidic environment for the subsequent reaction. …”
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Efficacy and safety of topical vs. oral calcium channel blockers for chronic anal fissures: a systematic review and meta-analysis by Tianshuo Li, Pengfei Ye, Xinli He, Chen Li, Lanlan Xi, Zuowu Xi

“…Random-effects models were used to pool effect sizes, with sensitivity analyses to assess robustness. …”
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A Systematic Review of Pneumonitis Following Treatment with Immune Checkpoint Inhibitors and Radiotherapy by Melina Yerolatsite, Nanteznta Torounidou, Anna-Lea Amylidi, Iro-Chrisavgi Rapti, George Zarkavelis, Eleftherios Kampletsas, Paraskevi V. Voulgari

“…We assessed the risk of bias using the Cochrane Risk of Bias Tool version 2 for randomized controlled trials and the RTI Risk of Bias Item Bank for non-randomized trials. …”
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Numerical Simulation of the Impact of Oxygen Enrichment Technology on Fuel Combustion and CO Emissions During Sintering by Zhen LI, Zhengjian LIU, Jianliang ZHANG, Yaozu WANG

“…We employed Computational Fluid Dynamics (CFD) to develop separate models for the combustion of fuel particles and for sintering machines. …”
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Neutrophil-to-albumin ratio mediates the association between Life’s Crucial 9 and chronic obstructive pulmonary disease by Jing Feng, Hongyang Gong

“…These findings highlight the potential value of optimizing cardiovascular health in COPD prevention strategies and underscore the importance of controlling inflammation and improving nutritional status. …”
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Healthcare provider interventions to support medication adherence: state-of-the-science overview by Jacob Crawshaw, Nicola McCleary, Nicola McCleary

“…Hundreds of randomized controlled trials and dozens of systematic reviews on the effectiveness of HCP-delivered interventions have been conducted to date. …”
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Associations of interpersonal and socioeconomic early life adversity dimensions with adolescents’ corticolimbic circuits, cognition, and mental health by Yumeng Yang, Tianjiao Kong, Ran Liu, Liang Luo

“…However, associations of threat, unpredictability, and deprivation in dimensional models of ELA with corticolimbic circuits were unclear. …”
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BARD1 serum autoantibodies for the detection of lung cancer. by Maxim Pilyugin, Pascaline Descloux, Pierre-Alain André, Viktoria Laszlo, Balazs Dome, Balazs Hegedus, Sylvain Sardy, Samuel Janes, Andrea Bianco, Geoffrey J Laurent, Irmgard Irminger-Finger

“…Using fitted Lasso logistic regression we determined the optimal combination of BARD1 antigens to be used in ELISA for discriminating lung cancer from healthy controls. …”
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The prevalence and correlates of biomarker positive unhealthy alcohol use among women living with and without HIV in San Francisco, California. by Jennifer P Jain, Yifei Ma, Carol Dawson-Rose, Glenn-Milo Santos, Alvina Han, Jennifer Price, Judith A Hahn, Phyllis C Tien

“…Using multivariable logistic regression, we identified the correlates of PEth levels suggestive of unhealthy alcohol use (>50 ng/ml) among the 168 women who reported no or low-risk drinking (<7 drinks per week) in the past six months, while controlling for age in years and race/ethnicity. Among the 168 women in the analysis sample, the median age was 55; 51% identified as Black/African American, 47% were living with HIV and 28% had PEth levels ≥50 ng/ml which are suggestive of unhealthy alcohol use. …”
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Pharmacological treatment for connective tissue disease-associated interstitial lung involvement: Protocol for an overview of systematic reviews and meta-analyses. by Fotini B Karassa, Konstantinos I Bougioukas, Eleftherios Pelechas, Anastasia Skalkou, Evangelia Argyriou, Anna-Bettina Haidich

“…However, there is uncertainty on what constitutes the optimal treatment options from a variety of competing interventions. …”
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Beyond Anesthesia: Ketamine’s Expanding Role in Chronic Pain and Psychiatric Disorders by Christopher Zaki

“…Ongoing research is needed to optimize dosing strategies, assess long-term safety, and integrate ketamine into multidisciplinary care models. …”
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Emerging trends in synthesis, characterization, and mechanism of action of antibody-drug and antibody-nanoparticle conjugates by Tanu Dixit, Annamraju Aswini, Harshal Nikam, Anuradha Vaidya, Selvan Ravindran

“…Despite progress, both platforms face translational hurdles: ADCs contend with manufacturing complexity and resistance mechanisms, while ACNPs require standardized in vitro models to predict in vivo behavior. This review emphasizes the significance of comparative efficacy studies and strategies for optimizing antibody density and orientation on nanoparticles. …”
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