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10581
Association between early enteral nutrition and 28-Day mortality in mechanically ventilated patients with sepsis: a retrospective analysis of the MIMIC-IV database
Published 2025-04-01“…The sensitivity and robustness of the evaluation results under different models, including optimal matching (adjusted odds ratio (aOR) 1.52, 95% CI 1.21–1.92, p < 0.001), inverse probability of treatment weighting (aOR 1.27, 95% CI 1.02–1.58, p = 0.034), and logistic regression analysis (aOR 1.48, 95% CI 1.18–1.84, p = 0.001), confirmed the association between early enteral nutrition and increased 28-day mortality in mechanically ventilated septic patients. …”
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10582
Dual-targeted N-PMIplus@CA nanoplatform for concurrent MDM2 and β-catenin inhibition in p53 wild-type lung adenocarcinoma
Published 2025-10-01“…The dual-inhibition strategy significantly restored p53 function, downregulated β-catenin signaling, suppressed tumor proliferation, and promoted apoptosis in LUAD cell lines and murine models. Remarkably, treatment with N-PMIplus@CA yielded superior antitumor efficacy in subcutaneous and orthotopic LUAD models compared with monotherapy controls, without detectable systemic toxicity. …”
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10583
Sustained Release of αO-Conotoxin GeXIVA[1,2] via Hydrogel Microneedle Patch for Chronic Neuropathic Pain Management
Published 2025-04-01“…This study developed a sustained-release hydrogel microneedle patch encapsulating GeXIVA[1,2] to address these challenges. Optimized 4:3 (<i>w</i>/<i>w</i>) polyvinyl alcohol (PVA)–sucrose hydrogel formulation achieved 98.6% structural integrity and controlled swelling (ratio = 1.9 at 48 h). …”
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10584
Investigating hydrocarbon potential utilizing isopach maps in the paleo-environment of the external Fars region, Zagros fold-thrust belt
Published 2025-06-01“…Notably, the findings reveal that the Nezamabad Fault functions as a significant basement fault, actively controlling hydrocarbon distribution during geological epochs. …”
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10585
Evolution of burnout syndrome in Spanish healthcare professionals during and after the COVID-19 pandemic: psychosocial variables involved
Published 2025-02-01“…The results of the repeated measures General Linear Models, after controlling for the effect of the covariates show that the evolution of emotional exhaustion is associated with the levels of depression at T1 (p = 0.031), of cognitive fusion at T2 (p < 0.001) and of resilience at T2 (p = 0.039). …”
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10586
Change in Stress Among Individuals with Chronic Health Conditions and Low Health Literacy Using a Tailored Communication App Promoting Self-Management
Published 2025-06-01“…Latent growth curve modeling (LGM) computed in Mplus was used to assess changes in stress over time and its impact on quality of life. …”
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10587
Dataset on the long-term monitoring of foundation vertical deformations on medium-expansive soilMendeley Data
Published 2025-04-01“…This is necessary for understanding the soil-structure interaction under natural field conditions, which differs considerably from controlled laboratory studies. This dataset presents a great possibility of being reused by researchers to support further studies on soil-structure interaction, develop predictive models for expansive soils, and analyze long-term structural stability. …”
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10588
A Review on Automated Detection and Identification Algorithms for Highway Pavement Distress
Published 2025-05-01“…To address these gaps, we propose four future directions: (1) enhancing environmental adaptability through multi-sensor datasets, (2) optimizing datasets via self-supervised learning, (3) deploying lightweight models on edge devices for real-time analysis, and (4) integrating predictive maintenance frameworks. …”
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10589
Numerical analysis of the influence of sidewalls on full-span finite-width cavity flows
Published 2025-12-01“…Additionally, the observed upper bound of secondary flow energy and Reynolds stresses in full-span cases identifies an optimal finite width, offering valuable insights for controlling flow oscillations and energy extraction in full-span finite-width cavity flows.…”
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10590
Divisor equitably strong non-split divisor equitable domination in graphs
Published 2025-02-01“… In epidemiology, the spread of diseases can be modelled using graphs, where individuals are nodes, and edges represent potential pathways for disease transmission. …”
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10591
Methane Synthesis as a Source of Energy Loss Impacting Microbial Protein Synthesis in Beef Cattle—A Review
Published 2025-04-01“…This review underscores the need for integrated approaches combining dietary strategies, advanced feed additives, and improved prediction models to optimize ruminal fermentation, enhance MPS, and reduce the environmental footprint of beef cattle systems.…”
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10592
Association of OAS1 and MxA variants with COVID-19 in Pakistani patients
Published 2024-09-01“…Results: The OAS1 gene rs2660 exhibited an association with COVID-19 susceptibility in various genetic models. The risk decreased with AG genotype (OR = 0.23, 95% CI = 0.09-0.58; p = 0.0011) compared to GG in codominant models. …”
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10593
From in vitro development to accessible luminal interface of neonatal bovine-derived intestinal organoids
Published 2025-05-01“…Rectal organoid-derived monolayers were further assessed by electron microscopy and barrier function assays, demonstrating stable transepithelial electrical resistance and controlled paracellular permeability. Conclusions Optimized methods for adult bovine intestinal organoids and rectal organoid-derived monolayers are applicable to neonatal intestinal epithelial stem cells. …”
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10594
GAMMA-SPECTROMETER FOR WATER AREAS AND BOTTOM SEDIMENTS RADIATION MONITORING
Published 2016-12-01“…The spectrometer can output measurement results with threedimensional geographical coordinates as index maps of distribution with necessary resolution and accuracy. Monte Carlo models of spectrometer and controlled objects are developed in order to determine the detector response functions to given radionuclides in given measurement geometries without use of expensive standard measures of activity. …”
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10595
Mechanism-based subtyping in binge eating: understanding neurobehavioral heterogeneity across negative emotionality, approach behavior, and executive function
Published 2025-06-01“…We analyzed data from 612 participants (ages 18–59, 66% female) from the enhanced Nathan Kline Institute-Rockland Sample, including 461 controls and 151 individuals with BE behaviors. Using data-driven statistical modeling of comprehensive, multimodal measures across the three hypothesized domains, we identified subtypes of BE. …”
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10596
Return to Play and Functional Outcomes Following Treatment of Acute Achilles Tendon Ruptures: A Systematic Review and Meta-Analysis
Published 2024-12-01“…The included studies were assessed regarding the level and quality of evidence. Fixed-effects models were employed for I2 < 25% and random-effects models for I2 ≥ 25%. …”
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10597
Effectiveness of mobile stroke units in reducing time to thrombolysis in acute ischemic stroke: a scoping review
Published 2025-06-01“…Included randomized controlled trials (RCTs), observational studies, and meta-analyses (using both fixed-effects and random-effects models) were synthesized narratively, with data on time reductions, treatment rates, outcomes, and limitations extracted by two blinded reviewers (NA and EK) and tabulated. …”
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10598
Capacitive Sensing of Solid Debris in Used Lubricant of Transmission System: Multivariate Statistics Classification Approach
Published 2025-07-01“…Controlled tests were performed using five mixing ratios of large-to-small particles (100:0, 75:25, 50:50, 25:75, and 0:100) at a fixed debris mass of 0.5 g per 25 mL of SAE 85W-140 automotive gear oil. …”
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10599
Design and high strain rate response of a nanostructured bainitic steel for enhanced austenite stability
Published 2025-07-01“…A combination of thermodynamic modeling (MUCG83) and advanced processing techniques, including electro-slag remelting and controlled austempering, was employed to tailor the transformation behavior. …”
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10600
Social Compliance With NPIs, Mobility Patterns, and Reproduction Number: Lessons From COVID-19 in Europe
Published 2025-01-01“…Non-pharmaceutical interventions (NPIs), such as lockdowns, travel restrictions, and social distancing mandates, play a critical role in controlling the spread of infectious diseases by shaping human mobility patterns. …”
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