Encapsulation of Nicardipine Hydrochloride and Release from Biodegradable Poly(D,L-lactic-co-glycolic acid) Microparticles by Double Emulsion Process: Effect of Emulsion Stability... by Nopparuj Soomherun, Narumol Kreua-ongarjnukool, Sorayouth Chumnanvej, Saowapa Thumsing

“…Poly(D,L-lactic-co-glycolic acid) (PLGA) is an important material used in drug delivery when controlled release is required. The purpose of this research is to design and characterize PLGA microparticles (PLGA MPs) implants for the controlled release of nicardipine hydrochloride (NCH) in vitro. …”
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Effectiveness of Biochar on Cd Migration and Bioaccumulation in a Multi-Species Alkaline Fluvo-Aquic Soil System by Dongqin Li, Changhong Lai, Hongzhi He, Dian Wen, Yiran Cao, Zhichao Wu, Furong Li, Hanzhi Shi, Xu Wang, Guikui Chen

“…However, alkaline stress from biochar suppressed wheat biomass by 42%, while earthworm Cd concentrations rose 30–45%, correlating with reduced survival (75% vs. 85–87% in controls). Structural equation modeling identified pH-driven chemisorption as the primary Cd immobilization mechanism, yet biochar amplified ecotoxicity to soil fauna. …”
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Optimising research investment by simulating and evaluating monitoring strategies to inform a trial: a simulation of liver fibrosis monitoring by Alice J. Sitch, Jacqueline Dinnes, Jenny Hewison, Walter Gregory, Julie Parkes, Jonathan J. Deeks

“…This work highlights the data necessary and the general method for evaluating the performance of monitoring strategies, allowing appropriate strategies to be selected for evaluation. Modelling work should be conducted prior to full scale investigation of monitoring strategies, allowing optimal monitoring strategies to be assessed.…”
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Microbial Biosensor for Sensing and Treatment of Intestinal Inflammation by Duolong Zhu, Jeffrey Galley, Jason Pizzini, Elena Musteata, Martin V. Douglas, Walter J. Chazin, Eric P. Skaar, Jeffrey J. Tabor, Robert A. Britton

“…Abstract Synthetic biology has enabled the development of biosensors to detect intestinal inflammation, yet few target the clinically validated biomarker of intestinal inflammation calprotectin with both diagnostic and therapeutic capabilities. Here, an optimized calprotectin biosensor is presented that leverages a zinc uptake regulator (Zur) controlled promoter coupled with a memory circuit to detect and record intestinal inflammation in vivo. …”
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NEW APPROACH TO ADDITIONAL LEFT-TURN SECTIONS OF THE TRAFFIC SIGNAL REGULATION by A. P. Zhigadlo, S. V. Dorokhin, D. V. Likhachev

“…The authors explained that the new approach, which took into account such parameters as speed, vehicle delays and queue length, allowed effectively controlling the intersection due to the optimal choice of the necessary traffic organization method and due to the result of changes in the parameters by combining the intensity of the left-turn flow and forward flow.Results. …”
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An elasticity-curvature illusion decouples cutaneous and proprioceptive cues in active exploration of soft objects. by Chang Xu, Yuxiang Wang, Gregory J Gerling

“…Our findings shed light on how we volitionally explore soft objects, i.e., by controlling surface contact force to optimally elicit and integrate proprioceptive inputs amidst indiscriminable cutaneous contact cues. …”
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VR interactive input system based on INS and binocular vision fusion by Hongxia Zhao, Bei Wang

“…This study explores the application of inertial measurement units and binocular vision fusion technology in virtual reality interactive input systems, with the aim of improving the tracking accuracy of the system through optimized pose models and visual algorithms. A virtual reality measurement technology that integrates inertial measurement units and binocular vision is proposed by using an improved Kalman filtering algorithm to process inertial measurement units data, and combining it with the SURF algorithm optimized binocular vision system. …”
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Extracted step parameters during the timed up and go test discriminate between groups with different levels of cognitive ability—a cross-sectional study by Niklas Löfgren, Lars Berglund, Vilmantas Giedraitis, Kjartan Halvorsen, Erik Rosendahl, Kevin J. McKee, Anna Cristina Åberg

“…The optimal cut-off indicated a step length of less than 32.9% (CI95 = 22.1–43.0) of body height to identify SCI compared with controls. …”
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The Relationship Between Nutrition Knowledge and Dietary Behavior of Student-Athletes by Kerry Smith, Kathleen Fritch, James Rost, Amy Jo Riggs, Juliann McBrayer, Monika Krah

“…Correlation between nutrition knowledge and dietary behavior and hierarchical linear regression modeling were utilized in this study. No significant relationship was found between nutrition knowledge and dietary behavior while controlling for the identified covariates. …”
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Trends in Myocardial Infarction risk by HIV status in two U.S. healthcare systems. by Alexandra N Lea, Asya Lyass, Leo B Hurley, Rachel Q Ehrbar, Taylor F Mahoney, Leila H Borowsky, Wei He, Jorge Plutzky, Virginia A Triant, Michael J Silverberg

“…Adjusted models controlled for demographics and traditional CVD risk factors. …”
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The effect of changing heat use patterns on residential energy efficiency in a Japanese smart community by Le Na Tran, Qian Wu, Huong Thanh Hoang

“…Given the lack of properly designated energy models for residential energy reduction, the primary objective of this study is to implement integrated energy prediction models and occupant-related parameters in proposing human-centered energy-saving and low-carbon building solutions. …”
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Precisely Tailoring Molecular Structure of Doxorubicin Prodrugs to Enable Stable Nanoassembly, Rapid Activation, and Potent Antitumor Effect by Chengcheng Feng, Yuting Wang, Jiaxu Xu, Yanzi Zheng, Wenhu Zhou, Yuequan Wang, Cong Luo

“…Carrier-free prodrug nanoassemblies, which rely on the design of prodrug molecules, offer a promising strategy to optimize both drug delivery efficiency and controlled drug release profiles. …”
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Assessment of the use of remote sensing methods to protect agricultural lands from invasive plants by Lugovskoy Alexander, Terekhin Mikhail, Perskaya Victoria, Morkovkin Dmitry, Wang Yanmin

“…The article substantiates the position that the optimal application of the method helps to solve the problem of controlling the distribution sites of hogweed and providing cartographic data on of Sosnowskyi's hogweed to the required territory. …”
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A Review of Recent Research on Flow and Heat Transfer Analysis in Additively Manufactured Transpiration Cooling for Gas Turbines by Kirttayoth Yeranee, Yu Rao

“…Previous research has concluded that well-designed transpiration cooling achieves cooling effectiveness up to five times higher than the traditional film cooling methods, minimizes jet lift-off, improves temperature uniformity, and reduces coolant requirements. Optimized coolant controls, graded porosity designs, complex topologies, and hybrid cooling architectures further enhance the flow uniformity and cooling effectiveness in AM transpiration cooling. …”
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A Video Dataset for Classroom Group Engagement Recognition by Weigang Lu, Yang Yang, Runfei Song, Ying Chen, Tao Wang, Cunling Bian

“…Recognition of group engagement in the classroom helps us understand students’ learning state and optimize teaching and study processes. While existing research predominantly focuses on individual engagement recognition through controlled lab-based computer interactions, this paradigm was fundamentally misaligned with authentic classroom dynamics. …”
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Hyperbaric oxygen therapy as a potential treatment for post-traumatic stress disorder associated with traumatic brain injury by Eve DJ, Steele MR, Sanberg PR, Borlongan CV

“…There is some evidence of a putative prophylactic or preconditioning benefit of HBOT exposure in animal models of brain injury, and the optimal time frame for treatment is yet to be determined. …”
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Effect of prophylactic low level laser therapy on oral mucositis: a systematic review and meta-analysis. by Sapna Oberoi, Gabriele Zamperlini-Netto, Joseph Beyene, Nathaniel S Treister, Lillian Sung

“…<h4>Methods</h4>MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials were searched until February 2014 for randomized controlled trials (RCTs) comparing prophylactic LLLT with placebo or no therapy in patients with cancer or undergoing hematopoietic stem cell transplantation (HSCT). …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…The adaptive architectural layout: How the control of a semi-autonomous mobile robotic partition was shared to mediate the environmental demands and resources of an open-plan office. …”
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Engineered Magnetic-Functionalized Carbon Xerogels for Sustainable Arsenic Removal: Bridging Adsorption Efficiency with Regenerability by Sasirot Khamkure, Prócoro Gamero-Melo, Audberto Reyes-Rosas, Alejandro Zermeño-González, José Luis Álvarez-Cruz, Elim Albiter Escobar, Gabriela Eleonora Moeller-Chávez, Victoria Bustos-Terrones

“…Adsorption kinetics followed Elovich (R² = 0.9396) and Power Function (R² = 0.9443) models, indicating chemisorption dominance. Response Surface Methodology optimized desorption parameters using a Central Composite Design with three factors and two center points with repetition. …”
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Electrospun composite nanofibers for wound healing: synthesis, characterization, and clinical potential of biopolymer-based materials by Prashant D. Yadav, Pramod V. Londhe, Sachin S. Chavan, Dadaso D. Mohite, Ghansham B. Firame, Sarang S. Kadam, Mahesh J. Patil, M. I. Ansari

“…Electrospinning is employed to produce these NFs with controlled diameters and morphologies. This review discusses the preparation methods, optimal electrospinning parameters, and challenges like solution viscosity and environmental conditions. …”
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