Fractionated stereotactic radiotherapy of brainstem metastases – Clinical outcome and prognostic factors by Anna Krämer, Laura Hahnemann, Fabian Schunn, Christoph A. Grott, Michael Thomas, Petros Christopoulos, Jonathan W. Lischalk, Juliane Hörner-Rieber, Philipp Hoegen-Saßmannshausen, Tanja Eichkorn, Maximilian Y. Deng, Eva Meixner, Kristin Lang, Angela Paul, Fabian Weykamp, Jürgen Debus, Laila König

“…Overall survival (OS), local control (LC) and total intracranial brain control (TIBC) were analyzed via Kaplan-Meier method. …”
Get full text

Regenerative ability and micropropagation of <I>Petunia hybrid</I> in vitro by S. A. Borovaya, N. G. Boginskaya

“…The pot culture of the regenerants was established under controlled conditions in a light room (photoperiod was 16 hours, temperature was 23°С).Results. …”
Get full text

Structure activity relationship of dendrimer microbicides with dual action antiviral activity. by David Tyssen, Scott A Henderson, Adam Johnson, Jasminka Sterjovski, Katie Moore, Jennifer La, Mark Zanin, Secondo Sonza, Peter Karellas, Michael P Giannis, Guy Krippner, Steve Wesselingh, Tom McCarthy, Paul R Gorry, Paul A Ramsland, Richard Cone, Jeremy R A Paull, Gareth R Lewis, Gilda Tachedjian

“…<h4>Conclusions</h4>Dendrimers can be engineered with optimized potency against HIV and HSV representing a unique platform for the controlled synthesis of chemically defined multivalent agents as viral entry inhibitors. …”
Get full text

Effect of caffeine ingestion on time trial performance in cyclists: a systematic review and meta-analysis by Bin Chen, Li Ding, Qiyang Qin, Tze-Huan Lei, Olivier Girard, Yinhang Cao

“…The selected studies comprised crossover, placebo-controlled investigations into the effects of caffeine ingestion on cycling TT performance. …”
Get full text

Emergence of porcine-derived hybrid Escherichia coli with dual-disease manifestations in intestinal and extraintestinal niches by Xinming Pan, Jianan Liu, Zhonghao Chen, Caiying Li, Rong Chen, Zhen Zhang, Song Liang, Zongfu Wu, Huochun Yao, Jiale Ma

“…These findings underscore the prevalence of hybrid pathogenic E. coli strains in pigs, presenting new challenges for disease control.…”
Get full text

Region-based U-nets for fast, accurate, and scalable deep brain segmentation: Application to Parkinson Plus Syndromes by Mengyu Li, Magnús Magnússon, Ingibjörg Kristjánsdóttir, Sigrún Helga Lund, Thilo van Eimeren, Lotta M. Ellingsen

“…The source code and trained model will be made publicly available on GitHub.…”
Get full text

Heterogeneity of Locked‐Pasture Snow Conditions Modulate Habitat and Movement Choices of a Facultative Migrant by Katherine B. Gura, Glen E. Liston, Adele K. Reinking, Bryan Bedrosian, Kelly Elder, Anna D. Chalfoun

“…We used a novel ecological application of SnowModel, a snow evolution modeling system, to estimate fine‐scale, physical snow properties likely to influence access to prey. …”
Get full text

Spatial Conflicts of Productive-Living-Ecological Land in Urumqi City of Xinjiang Wei Autonomous Region by Wang Shanshan, Wu Zhaopeng, Wang Juanjuan, Yin Huihui, Li Bincai

“…[Methods] A spatial conflict measurement model at the grid scale was constructed for Urumqi City from the three factors of external pressure, vulnerability, and stability. …”
Get full text

Therapeutic and Prognostic Potential of G Protein‐Coupled Receptors in Lung Adenocarcinoma: Evidence From Transcriptome Data and In Vitro Experiments by Feiyan Yang, Jianye Yang, Guobiao Yang, Ya Zhang

“…The model established based on these five genes harbored moderate predictive performance for the survival of patients with LUAD. …”
Get full text

Factors determining cognitive, motor and language scores in low birth weight infants from North India. by Ravi Prakash Upadhyay, Sunita Taneja, Suman Ranjitkar, Sarmila Mazumder, Nita Bhandari, Tarun Dua, Laxman Shrestha, Tor A Strand

“…<h4>Methods</h4>This secondary data analysis was conducted using data from LBW infants enrolled soon after birth in an individually randomized controlled trial (RCT) and followed up till end of 1st year. …”
Get full text

Sensor-Integrated Inverse Design of Sustainable Food Packaging Materials via Generative Adversarial Networks by Yang Liu, Lanting Guo, Xiaoyu Hu, Mengjie Zhou

“…An enhanced EquiformerV2 graph neural network was employed to accurately predict the formation energy, stability, and sensor-measurable properties of candidate materials. The model achieved a mean absolute error of 12 meV/atom for formation energy on the OMat24 test set (25% improvement over baseline models), while predictions of sensor-measured functional properties reached <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mi>R</mi><mn>2</mn></msup></semantics></math></inline-formula> values of 0.84–0.89 through the integration of experimental measurements and physics-based proxy models. …”
Get full text

Efficacy and safety of quadriceps tendon autograft versus bone–patellar tendon–bone and hamstring tendon autografts for anterior cruciate ligament reconstruction: a systematic revi... by Xiao-Feng Zhang, Pan Liu, Jun-Wu Huang, Yao-Hua He

“…All pooled analyses were performed using a random-effects model. Results Twenty-one studies (3 randomized controlled trials [RCTs], 3 prospective studies, and 15 retrospective studies) involving 2964 patients with ACLR were selected for meta-analysis. …”
Get full text

A hybrid recommendation system for Chinese character components using a dual-tower neural network and a deterministic algorithm by Shaoqing Yang

“…Furthermore, this enhanced awareness strongly correlates with HSK progression (r = 0.71, p < 0.01), suggesting that the proposed framework provides a solid foundation for sustained language acquisition.Future research will implement transformer-based behavior modeling to advance adaptive personalization. While this work focuses on optimizing for mobile accessibility using a dual-tower architecture, future research will explore lightweight Transformer-based models to capture dynamic contextual semantics for more complex character structures.…”
Get full text

Navigating the shots: Parental willingness to immunize their children with COVID-19 vaccines in Saudi Arabia explored through a systematic review and meta-analysis. by Moustafa Abdelaal Hegazi, Mohamed Hesham Sayed, Nadeem Shafique Butt, Turki Saad Alahmadi, Nadeem Alam Zubairi, Wesam Abdelaziz Elson

“…<h4>Conclusion</h4>This was the first SRMA from Saudi Arabia which emphasized the priority to focus on vaccine-related factors as main/key strategy of COVID-19 vaccines' drivers to convince parents in a logical way based on accurate cumulative and emerging scientific data about efficacy and safety of COVID-19 vaccines to optimize their uptake by children/adolescents. This SRMA can provide valuable insights for development of evidence-based policies to improve parental willingness to vaccinate children, which is crucial for controlling SARS-CoV-2 spread and promoting herd immunity in the community particularly if the virus continues to pose a major threat.…”
Get full text

Analytic Buckling Solution of Composite Classical Rectangular Thin Plates Using Galerkin Variational Approach by Thompson Edozie Okeke, Festus Chukwudi Onyeka, Uzor Onyia, Benjamin Nnamdi Ekwueme

“…Furthermore, a significant percentage difference is noted when comparing approximate solutions, while a low percentage difference of 0.43% with the author’s derived displacement function indicates close agreement, demonstrating the high level of accuracy and reliability of the proposed model in predicting buckling load of plates. Hence, it can be recommended for stability analysis, especially where the material properties need to be controlled in a specific direction to optimize performance.…”
Get full text

The impact of physical activity on working memory in children with ADHD: a meta-analysis by Gong Cheng, Gong Cheng, Ce Song, XiaoQin Hong

“…Standardized mean differences were calculated using a random-effects model. Subgroup analyses were conducted by intervention characteristics such as duration, frequency and total time. …”
Get full text

Mind–body training outperforms other physical activities in reducing frailty and enhancing quality of life in older adults: a network meta-analysis by Guangwen Liu, Renkai Ge, Huiling Zhu

“…Future studies should focus on long-term effects and dose–response relationships to optimize frailty management and health promotion in older adult individuals.…”
Get full text

Association between triglyceride-glucose related indices and at-risk NASH in U.S. adults with NAFLD: results from NHANES 2017-2020 by Hanchen Ma, Wenjie Zhang, Wenjie Zhang, Zheng Zhao, Shuaichen Jin, Linchuan Li, Linchuan Li, Ruizhao Zong, Ruizhao Zong, Wuyang Li, Wuyang Li, Ziwei Zhang, Ziwei Zhang, Shichang Cui, Shichang Cui, Yunmiao Pan, Jiankang Zhu, Jiankang Zhu, Guangyong Zhang, Guangyong Zhang, Guangyong Zhang

“…Composite indices (TyG-WC, TyG-WHR, TyG-WtHR, TyG-BMI) each showed higher ORs than TyG alone in Model 3. TyG-WtHR exhibited the strongest association both as a continuous variable and across tertiles in Model 3, demonstrating a near-linear dose-response relationship. …”
Get full text

Polymer-Functionalized Magnetic Nanoparticles for Targeted Quercetin Delivery: A Potential Strategy for Colon Cancer Treatment by Júlia Borges de Macedo, Julia Narayana Schoroeder Bueno, Carla Cristine Kanunfre, José Ricardo de Arruda Miranda, Andris Figueiroa Bakuzis, Priscileila Colerato Ferrari

“…The 24 h drug release was controlled in MNP-CS-Q (up to 6.4%) and MNP-FA-CS-Q (up to 7.7%) in a simulated tumor medium, with Fickian diffusion release mechanism correlated to the Korsmeyer–Peppas model (R > 0.99). …”
Get full text

Smart photonic wristband for pulse wave monitoring by Renfei Kuang, Zhuo Wang, Lin Ma, Heng Wang, Qingming Chen, Arnaldo Leal Junior, Santosh Kumar, Xiaoli Li, Carlos Marques, Rui Min

“…The results indicated that the smart photonic wristband had a high signal-to-noise ratio and low latency, with the measurement error controlled at approximately 3.7%. This optimized pulse signal could be used for further medical diagnosis and was capable of objectively monitoring subtle pulse signal changes, such as the pulse waveform at different positions of Cunkou and pulse waveforms before and after exercise. …”
Get full text