Immunoinformatic-driven design and evaluation of multi-epitope mRNA vaccine targeting HIV-1 gp120 by Muhammad Zeeshan Ahmed, Muhammad Zeeshan Ahmed, Tazeen Rao, Zeeshan Mutahir, Sarfraz Ahmed, Najeeb Ullah, Suvash Chandra Ojha

“…Molecular docking and simulation revealed a strong and stable binding affinity of vaccine immunization with immune cells’ pattern recognition receptors (TLR4). Immune simulations demonstrated a potent primary immune response characterized by a gradual increase in immunoglobulins and a corresponding decline in antigen concentration. …”
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Evaluating hepatitis B screening, prevalence, vaccination coverage, and linkage to care in Abuja, Nigeria: insights from a cross-sectional study by Ogechukwu MaryAnn Akabuike, Mabel Kamweli Aworh, Nkiruka Lynda Uzoebo, John Erwat, Onyinyechi Agukwe, Kingsley Ngong, Amos Dangana, Kenneth Enwerem, Idris Nasir Abdullahi

“…Vaccination uptake declined with each subsequent dose, but more older participants completed the third dose. A similar pattern of HBV prevalence was observed across gender and age groups. …”
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Comprehensive overview of genotype distribution and prevalence of human papillomavirus in cervical lesions by Yang Liu, Chengquan Zhao, Tiannan Wang, Yuhong Ye, Terrel Jones, Xianxu Zeng

“…Women with atypical glandular cell (AGC) Pap test results showed a specific HPV genotyping pattern and extended HPV genotyping may be helpful for the clinical management of AGCs. …”
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Effect of breast milk olfactory experience on physiological indicators in very low birth weight infants: a randomized clinical trial by Ling Yu, Yibo Tao, Pin Jia, Liling Li, Tianchan Lv, Li Wang, Qinqin Song, Xia Huan, Chan Liu, Yalan Dou, Yan Xuan, Xiao-jing Hu

“…A narrower range of fluctuation was observed across all physiological indicators in the intervention group, indicating a more stable pattern compared to the control group. Although no significant difference was found in heart rate variability (50.35 ± 9.61 vs. 48.03 ± 10.2, t=-1.320, P = 0.187), a significant difference was noted in the average heart rate between the two groups (155.65 ± 6.80 vs. 153.58 ± 4.22, t=-2.141, P = 0.032). …”
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Mechanisms and equation improvement for gas seepage in coal seams around boreholes subjected to high-pressure CO2 foam fracturing by Mingkun PANG, Tianyu ZHANG, Hongyu PAN, Xianfeng SONG, Shan WU, Tianjun ZHANG

“…MethodsUsing an independently developed apparatus for gas seepage experiments on fractured coals around boreholes, this study investigated the coals with pores and fractures distributed in an annular pattern around boreholes from the perspective of varying initial pore structures. …”
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Study on the Response of Cotton Leaf Color to Plant Water Content Changes and Optimal Irrigation Thresholds by Binbin Mao, Lulu Wang, Junhui Cheng, Bing Chen, Jiandong Wang, Kai Zhang, Xiaowei Liu

“….; (2) plant water content continuously decreased across five measurement periods following irrigation during the bud, flowering, and boll development stages, with R and G color values of the five functional leaves showing declining trends between 2:30 p.m. and 7:00 p.m., while B color values exhibited no consistent pattern; (3) correlation analysis revealed significant positive correlations between plant water content and R and G color values of the five functional leaves during the 2:30 p.m. to 5:00 p.m. period, with highly significant correlations observed for the third and fourth leaves from the apex; (4) univariate and bivariate linear regression models were successfully established between cotton water content and R and G color values of the third and fourth leaves from the top; and (5) under 72% plant water content conditions, cotton achieved the highest yield and Irrigation Water Use Efficiency, indicating that 72% represents the optimal irrigation threshold. …”
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Results of the population study of the prevalence and risk factors of the food intolerance in children of different school age by О. Р. Pakholchuk

“…But specific IgE levels to food showed other pattern: it increases in young school children in two times and decreases in elders. …”
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Characteristics, health care utilization and cost of patients hospitalized with heart failure by Hanna Winkler, Dorothee Riedlinger, Andrea Figura, Liane Schenk, Martin Möckel, Thomas Reinhold

“…To provide optimal care to these high-risk patients, it is important to know their characteristics and health care utilization patterns.MethodsThis secondary data analysis of the EMANet data set used data from the hospital information system (HIS) of eight hospitals from the center of Berlin to identify patients with heart failure having had at least one hospital treatment during the year 2016. …”
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Trace elements composition of the scleral shell of the eye in various forms of glaucoma by L. L. Arutyunyan, E. N. Iomdina, Yu. S. Morozova, S. Yu. Anisimova, S. I. Anisimov

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Decoding Artificial Intelligence: A Tutorial on Neural Networks in Behavioral Research by Javier Martínez-García, Juan José Montaño, Rafael Jiménez, Elena Gervilla, Berta Cajal, Antonio Núñez, Federico Leguizamo, Albert Sesé

“…Method: The tutorial guides readers step-by-step through building a backpropagation MLP using a simulated data matrix (N = 1,000) with psychological variables, demonstrating ANNs’ versatility in predicting continuous variables and classifying (binary and polytomous) patterns. …”
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Genotyping by Amplicon Sequencing (GBAS) With Newly Developed SSR and EPIC Markers Reveals Structure in Populations of the Green Toad (Bufotes viridis) Across Rural and Urban Envir... by Vincent Kendlbacher, Yoko Philipina Krenn, Thapasya Vijayan, Christina Rupprecht, Magdalena Spießberger, Manuel Curto, Lukas Landler, Harald Meimberg

“…Clustering methods using EPIC markers revealed ecologically coherent results, showing weaker genetic structure in rural environments, whereas the SSRs' signal reflected drift‐induced patterns. Our findings suggest that the green toad exhibits a degree of resilience to urban environments. …”
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Global, regional, and national disease burden of tobacco-related Alzheimer’s disease among individuals over the age of 55: a global burden of disease study by Tianyi Dong, Shipeng Zhang, Hanyu Wang, Yanjie Jiang, Qinxiu Zhang, Qinxiu Zhang, Xueying Li, Lanfang He, Lanfang He

“…This study aims to explore the epidemiological patterns and trends concerning tobacco-related Alzheimer’s disease at global, national and regional levels.MethodsWe analyzed data on mortality, age-standardized DALY rate (ASDR), and estimated annual percentage changes (EAPCs) sourced from the Global Burden of Disease data for 2021. …”
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Insights into Biological and Ecological Features of Four Rare and Endemic Plants from the Northern Tian Shan (Kazakhstan) by Gulbanu Sadyrova, Aisha Taskuzhina, Alexandr Pozharskiy, Kuralai Orazbekova, Kirill Yanin, Nazym Kerimbek, Saule Zhamilova, Gulzhanat Kamiyeva, Ainur Tanybaeva, Dilyara Gritsenko

“…Chloroplast genome assemblies revealed characteristic patterns of plastid evolution, including structural conservation in <i>S. nidulans</i> and <i>R. wittrockii</i>, and a reduced inverted repeat region in <i>A. rubtzovii</i>, consistent with its placement in the IR-lacking clade of Fabaceae. …”
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A Synergistic Approach Using Photoacoustic Spectroscopy and AI-Based Image Analysis for Post-Harvest Quality Assessment of Conference Pears by Mioara Petrus, Cristina Popa, Ana Maria Bratu, Vasile Bercu, Leonard Gebac, Delia-Mihaela Mihai, Ana-Cornelia Butcaru, Florin Stanica, Ruxandra Gogot

“…Additionally, artificial intelligence (AI) models, particularly convolutional neural networks (CNNs), were explored to enhance data interpretation, enabling early detection of ripening and spoilage patterns through volatile compound profiling. This study advances our understanding of post-harvest physiological processes and proposes new strategies for improving storage and distribution practices for climacteric fruits.…”
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Non-temperature environmental drivers modulate warming-induced 21st-century permafrost degradation on the Tibetan Plateau by Fu Ziteng, Wu Qingbai, Chen Anping, Wang Luyang, Jiang Guanli, Gao Siru, Yun Hanbo, Chen ji

“…Notably, precipitation patterns exert contrasting effects on permafrost: Increasing precipitation south of 34oN leads to active layer thinning and permafrost cooling, while in the north it deepens the active layer and warms permafrost. …”
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Aggregation potency and proinflammatory effects of SARS-CoV-2 proteins by Monica Costa, Da-Wei Wang, Kai-Dong Zhao, Lin Yuan, Anita Krisko, Jia-Yi Li, Tiago Outeiro, Wen Li

“…We observed distinct expression and distribution patterns of ten SARS-CoV-2 proteins in the two cell lines, meanwhile forming aggregation puncta and inducing pro-inflammatory responses. …”
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Simulation of the future evolution track of “production–living–ecological” space in a coastal city based on multimodel coupling and wetland protection scenarios by Yitong Yin, Rongjin Yang, Zechen Song, Yuying Zhang, Yanrong Lu, Le Zhang, Meiying Sun, Xiuhong Li

“…This paper provides a solid theoretical support for the sustainable management and protection of wetlands in coastal cities and possible PLES conflict patterns and provides a scientific basis for future territorial spatial planning and policy balance analysis.…”
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A review of sound-based pig monitoring for enhanced precision production by Md Nasim Reza, Md Razob Ali, Md Asrakul Haque, Hongbin Jin, Hyunjin Kyoung, Young Kyoung Choi, Gookhwan Kim, Sun-Ok Chung

“…The integration of machine learning and artificial intelligence (AI) is further enhancing the capacity to interpret complex sound patterns, enabling the automated detection of abnormal behaviors or health issues. …”
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Developing an Educational-career guidance Curriculum Framework in the Iran's Education system by Behrooz Rahimi, Rezvan Hakimzadeh, Mohammad Javadipour, Keyvan Salehi, Mohammad KHademi Koleh lou

“…The findings of the research, the elements and components of the educational-career guidance curriculum framework in Iran's education and training system in 6 elements and 17 components including; Logic (why, what), goals (development of educational, career, individual-social insight), content (learning areas, content organization pattern, content selection criteria), implementation (time, teacher-consultant, learning approach and activities, infrastructure and requirements) ), evaluation (role, process, tools and techniques) and learning outcomes (self-awareness, exploration and educational -career). …”
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Providing a model of purchase intention and customer experience on customer behavior in virtual networks by Kazem Tolooee, Hossein budaghi Khajeh Noubar, Hossein Gharehbiglo, Mojtaba Ramazani

“…The collection tool in this research includes a questionnaire of purchase intention pattern based on customers' experience in designed virtual networks. …”
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