CD32a receptor in health and disease by N. A. Arsentieva, O. K. Batsunov, I. V. Kudryavtsev, A. V. Semenov, Areg A. Totolian

“…Low-affinity Fcγ-receptors that recognize the Fc portion of immunoglobulin (Ig) molecules, usually being in antigen-bound state, thus representing a link between innate and adaptive immunity. …”
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Docking investigation of Thevetia peruviana plant compounds for targeting molluscicidal activity against Biomphalaria alexandrina snails, the intermediate host of Schistosoma manso... by Samah I. Ghoname, Basma H. Amin, Asmaa T. Mohamed, Olfat A. Hammam, Hebat-Allah A. Dokmak

“…The analysis of docking scores provides a quantitative measure of binding affinity, where more negative values indicate stronger interactions. …”
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New approach to generating of human monoclonal antibodies specific to the proteolytic domain of botulinum neurotoxin A by Marina Vladimirovna Silkina, Alena Sergeevna Kartseva, Alena Konstantinovna Riabko, Mariia Aleksandrovna Makarova, Metkhun Madibronovich Rogozin, Yana Olegovna Romanenko, Igor Georgievich Shemyakin, Ivan Alekseevich Dyatlov, Victoria Valerievna Firstova

“…Immunotherapy with neutralizing monoclonal antibodies (MAbs) is considered to be the most effective immediate response to BoNT exposure. …”
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DFT Studies on Physicochemical Properties and Spectral Data of 2-Thiophene Carboxylic Acid Thiourea Derivatives by Andreea Neacsu, Carmellina Badiceanu, Cristina Stoicescu, Viorel Chihaia

“…A vibrational analysis of the considered structures was performed, and the experimental FT-IR ATR spectra of the solid powders are presented.…”
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A review of studies on the roles of p75NTR in the tooth development and tissue regeneration by Shi-Ting LI, Xia YU, Xiu-Jie WEN

“…p75NTR, a low affinity neurotrophic factor receptor, is considered as a typical neural crest marker. …”
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Treatment of hypertension in obese patients: focus on telmisartan by I. E. Deneka, A. V. Rodionov, V. V. Fomin

“…The role of the adiponectin peptide is considered, which synthesis is stimulated by partial PPARy receptor agonists (as mentioned above — telmisartan). …”
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Pour un apprentissage/enseignement des collocations verbo-nominales d’existence en termes de ‘constructions’ by Catherine Fuchs, Sylvie Garnier

“…It is shown that the (more or less strong) compatibilities and the incompatibilities between verbs and nouns can be explained to learners in terms of the ‘facet’ (i.e. point of view) that the verb imposes on the name, according to its meaning in the construction considered. It is also shown that the comparison of two constructions expressing the same main idea makes it possible to measure their degree of semantic proximity, on the basis of the (in)compatibilities of verbs with the major categories of nouns, and of their more or less strong affinity (or absolute incompatibility) with the types of names. …”
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Exploiting subtractive genomics to identify novel drug targets and new immunogenic candidates against Bordetella pertussis: an in silico study by Mahshid Khazani Asforooshani, Mahshid Khazani Asforooshani, Narjes Noori Goodarzi, Narjes Noori Goodarzi, Behzad Shahbazi, Behzad Shahbazi, Nayereh Rezaie Rahimi, Kimia Mahdavian, Mahdi Rohani, Farzad Badmasti

“…SphB2-based MEV was designed using six linear B-cell epitopes of the extracellular loops of the autotransporters. The binding affinity and feasibility of the interaction between MEV and TLR2, TLR4, and HLA-DR-B were computationally confirmed by molecular dynamics.ConclusionIt appears that proteins involved in translation and metabolism can be considered novel drug targets. …”
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Reexamining the Characteristics of Assassination and Muhāribah in Imamiyyah Jurisprudence by Mustafa GHayoomzadeh, Ahmad Moradkhani, alireza asgari

“…Alongside this, the issue of assassination and targeted killings is also considered in criminal jurisprudence due to its conceptual and legal affinity with the discussions of Muhāribah. …”
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Geonics (geomimetics) and search for optimal solutions in building materials science by V. S. Lesovik, A. А. Sheremet, I. L. Chulkova, A. E. Zhuravleva

“…Methodological approaches and validation of the emergence of a new transdisciplinary area -geonics, which is considered as the art of applying knowledge of the inorganic world, are presented.Materials and methods. …”
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APTAMERS ARE NEW PHARMACOLOGICAL SUBSTANCES FOR THE DEVELOPMENT OF ANTICOAGULANTS by A. V. Mazurov, V. A. Spiridonova

“…In the future, such primary aptamers can be chemically modified to optimize their structure and increase stability. Aptamers are considered to be chemical (oligonucleotide) analogues of monoclonal antibodies: their specificity is similar to that of antibodies, and they have high affinity to their targets. …”
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Lamiyyat al-'Arab’s Binary Contrasts: A Study in Anthropology by Ali Akbar Noreside, Shaker Aamery, Maliha Yaqoubizade

“…The most important of these contrasts was the contrasts between the seclusion and affinity, pride and abjection, hunger and satiation, delicacy and hardness, patience and dread, etc. …”
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Robust Plasma Cell Response to Skin-Inoculated Dengue Virus in Mice by Raúl A. Maqueda-Alfaro, Edith Marcial-Juárez, Juana Calderón-Amador, Julio García-Cordero, Mariana Orozco-Uribe, Felipe Hernández-Cázares, Uziel Medina-Pérez, Luvia E. Sánchez-Torres, Adriana Flores-Langarica, Leticia Cedillo-Barrón, Juan C. Yam-Puc, Leopoldo Flores-Romo

“…Finally, we found a progressive appearance of high-affinity neutralizing DENV-specific IgG further supporting GC involvement. …”
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A human monoclonal antibody isolated from Japanese encephalitis virus vaccine-vaccinated volunteer neutralizing various flaviviruses by Dong Chen, Dong Chen, Dong Chen, Jiayi Zhang, Jiayi Zhang, Jiayi Zhang, Yusha Liu, Jiayang Zhu, Jie Chen, Hongxia Ni, Jinsheng Wen

“…The epitopes on E proteins of JEV/ZIKV recognized by mAb LZY3412 were analyzed using molecular docking and constructing E protein mutants.ResultsOur results show that recombinant mAb LZY3412 has high-affinity with the E proteins of three viruses, with the kinetically derived binding affinity (KD) values of 440 and 482.5 nM against JEV-E protein and ZIKV-E protein, respectively; recombinant mAb LZY3412 can efficiently neutralize JEV and ZIKV infections in vitro, with the NT50 values of 19.9 ng/mL and 631 ng/mL, respectively; application of recombinant mAb LZY3412 can significantly improve the percentage survival and reduce the serum viral loads of neonatal mice infected with JEV or ZIKV. …”
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THE ESSENCE OF AN IMAGE IN ENGLISH-AMERICAN IMAGISM: SINGULAR VERSUS UNIVERSAL by Yevheniya S. Chernokova.

“…And throughout Imagism development, this inner affinity is being weakened until a distant outer resemblance is left. …”
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Attenuated T cell responses to a high-potency ligand in vivo. by Emily Corse, Rachel A Gottschalk, Michelle Krogsgaard, James P Allison

“…Our results reveal a level of control over T cell activation in vivo not recapitulated in in vitro assays and highlight the importance of considering in vivo efficacy of TCR ligands as part of vaccine design.…”
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Effect of Volume Fraction of Carbon Nanotubes on Structure Formation in Polyacrylonitrile Nascent Fibers: Mesoscale Simulations by Pavel Komarov, Maxim Malyshev, Pavel Baburkin, Daria Guseva

“…This process represents one of the stages in the production of PAN composite fibers, which are considered as precursors for carbon fibers with improved properties. …”
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Vitamin D Binding Protein Impact on 25-Hydroxyvitamin D Levels under Different Physiologic and Pathologic Conditions by Pegah Yousefzadeh, Sue A. Shapses, Xiangbing Wang

“…We suggest that DBP should be considered in the interpretation of 25(OH)D levels.…”
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Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens by Michael K. Fenwick, Phillip G. Pierce, Jan Abendroth, Kayleigh F. Barrett, Lynn K. Barrett, Kalinga Bowatte, Ryan Choi, Ian Chun, Deborah G. Conrady, Justin K. Craig, David M. Dranow, Bradley Hammerson, Tate Higgins, Donald D. Lorimer, Peer Lukat, Stephen J. Mayclin, Stephen Nakazawa Hewitt, Ying Po Peng, Ashwini Shanbhogue, Hayden Smutney, Matthew Z. Z. Stigliano, Logan M. Tillery, Hannah S. Udell, Ellen G. Wallace, Amy E. DeRocher, Isabelle Q. Phan, Bart L. Staker, Sandhya Subramanian, Wesley C. Van Voorhis, Wulf Blankenfeldt, Rolf Müller, Thomas E. Edwards, Peter J. Myler

“…Although griselimycin clearly co-evolved with Gram-positive β-clamps, binding affinity measurements demonstrate that the high selectivity observed previously extends to the Gram-negative orthologs, with K D values ranging from 7 to 496 nM for the wild-type orthologs considered. …”
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Successful Management of a Giant Pituitary Lactosomatotroph Adenoma Only with Cabergoline by Emre Bozkirli, Okan Bakiner, Emine Duygu Ersozlu Bozkirli, Eda Ertorer, Neslihan Bascil Tutuncu, Nilgun Guvener Demirag

“…However, surgical or more aggressive approach must be considered where indicated.…”
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