GS-DTA: integrating graph and sequence models for predicting drug-target binding affinity by Junwei Luo, Ziguang Zhu, Zhenhan Xu, Chuanle Xiao, Jingjing Wei, Jiquan Shen

“…Abstract Background Drug-target binding affinity (DTA) prediction is vital in drug discovery and repositioning, more and more researchers are beginning to focus on this. …”
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Electroadhesion between a flat touchscreen and the human finger with randomly self-affine fractal surface by M. Feshanjerdi

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Fuzzy Adaptive Dynamic Surface Control with Constant Gain for Non-Affine Pure-Feedback Systems by Lian Chen, Yixu Wang, Jianjun Cui, Daiyue Wang, Song Ling

“…This paper considers tracking control of non-affine pure-feedback systems with uncertain disturbances. …”
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Evolving superpixel-level affinity based on contrastive learning and good neighbors for hyperspectral image clustering by Yao Qin, Guisong Xia, Kun Li, Yuanxin Ye, Weiping Ni

“…Recently, graph clustering has been applied to hyperspectral image (HSI) clustering and proves to be effective on capturing the complex affinity among hyperspectral samples to a certain extent. …”
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Evidence of variable human Fcγ receptor-Fc affinities across differentially-complexed IgG by Andrew R. Crowley, Matthew R. Mehlenbacher, Mohammad M. Sajadi, Anthony L. DeVico, George K. Lewis, Margaret E. Ackerman

“…Antibody-mediated effector functions are widely considered to unfold according to an associative model of IgG-Fcγ receptor (FcγR) interactions. …”
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Machine learning models for predicting interaction affinity energy between human serum proteins and hemodialysis membrane materials by Simin Nazari, Amira Abdelrasoul

“…Various membrane materials with distinct characteristics, chemistry, and orientation are considered in conjunction with different proteins. A comparative analysis of linear regression, K-nearest neighbors regression, decision tree regression, random forest regression, XGBoost regression, lasso regression, and support vector regression is conducted to predict affinity energy. …”
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Flavone and Flavonol derivatives as adenosine A1/A2A receptor ligands: Structure-affinity insights by Irna Groenewald, Helena D. Janse van Rensburg, Gisella Terre'Blanche

“…Remarkably, it was observed that methylation on the C3 position of ring C increased A1 AR affinity and selectivity. Although only four compounds showed A2A AR affinity, it was seen that replacing the phenyl ring B with a furan ring resulted in compound 39 with the best A2A affinity of 0.25 μM. …”
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GramSeq-DTA: A Grammar-Based Drug–Target Affinity Prediction Approach Fusing Gene Expression Information by Kusal Debnath, Pratip Rana, Preetam Ghosh

“…Drug–target affinity (DTA) prediction is a critical aspect of drug discovery. …”
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Quantifying antibody binding: techniques and therapeutic implications by James Lodge, Lewis Kajtar, Rachel Duxbury, David Hall, Glenn A. Burley, Joanna Cordy, James W.T. Yates, Zahra Rattray

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Comprehensive inventory of páramo birds and their habitat affinities in a conservation hotspot, the Macizo del Cajas Biosphere Reserve, southern Ecuador by Pedro X. Astudillo, Santiago Barros, Fernando R. Villegas, David C. Siddons, Steven C. Latta

“…We also provide notes on habitat affinity and important new, rare, restricted range, and threatened birds. …”
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Zero-Sum Game-Based Tracking Control for Fully-Coupled Nonaffine AUV With Unknown Affine Disturbance Using Critic Network by Gaofeng Che, Xiaoqiang Hu

“…In this paper, the unknown affine disturbance is considered and a two-player zero-sum game (TPZSG) is employed to design tracking control scheme for fully-coupled nonaffine AUV (FCNAUV). …”
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In Silico Profiling of Binding Affinities of Hybrid Molecules of Oseltamivir carboxamides cross-linked with Hydroxamic acid as possible Anti-influenza agents by Sumia Samer Tayah, Shakir Mahmood Alwan, Kenza Mansoor

“…These hybrids have recorded slightly higher PLP fitness, binding affinities represented as docking scores (59.14-72.23 Kcal/mol) based on the lowest docking scores on the target enzyme compared to Oseltamivir acid (56.24 Kcal/mol).    …”
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Low nanomolar affinity to major grass pollen allergen Phl p 5 as achieved in an unmutated human antibody-lineage ancestor by Mattias Essén, Eric Franciskovic, Céleste Sele, Magdalena Godzwon, Mats Ohlin, Mats Ohlin

“…This antibody, although subjected only to a low level of hypermutation resulting in six amino acid substitution across the heavy and light chain variable domains, has achieved sub-nM affinity for the allergen, suggesting that antibodies specific for this major group of allergens can be of high affinity even at the naïve, unmutated stage. …”
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Can Brand Affinity Outperform Political Parties' Rejection When Nominating Celebrity Politicians in a Post-Rebellion Multi-Party Context? by Maya A. BouNassif, Alaaeldin Abass, Amal El Kurdi

“…This study contributes to the moderating role of brand affinity towards celebrity politicians. It considers celebrities' cognitive perceived benefits and voting intention relationship in a multi-party parliamentarian election. …”
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Computational Investigation of Montelukast and Its Structural Derivatives for Binding Affinity to Dopaminergic and Serotonergic Receptors: Insights from a Comprehensive Molecular S... by Nasser Alotaiq, Doni Dermawan

“…MM/PBSA calculations quantified binding affinities, while ADME-Tox profiling predicted pharmacokinetic and toxicity risks. …”
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A quasi affine transformation evolution algorithm with evolution matrix selection operation for parameter estimation of proton exchange membrane fuel cells by Mohammad Aljaidi, Pradeep Jangir, Sunilkumar P. Agrawal, Sundaram B. Pandya, Anil Parmar, Samar Hussni Anbarkhan, Laith Abualigah

“…Abstract Electrochemical energy conversion technologies include proton exchange membrane fuel cells (PEMFCs) where proton interchange is an alternative to diesel distributed generation, and PEMFCs are considered as a promising backup power source and a tool to regulate power consumption. …”
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The Robust Control of a Nonsmooth or Switched Control-Affine Uncertain Nonlinear System Using an Auxiliary Robust Integral of the Sign of the Error (ARISE) Controller by Sujata Basyal, Jonathan Ting, Kislaya Mishra, Brendon Connor Allen

“…To deal with uncertainties in a dynamic system, many nonlinear control approaches have been considered. Unique challenges arise from uncertainties that are bounded by constants, which has led to the development of both continuous and discontinuous control methods. …”
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Mito Stress Assay of PBMCs With Seahorse XFe96 Flux Analyzer and Comparison of Poly-D-Lysine and Poly-L-Lysine for Cell Affinity by Kumudu Subasinghe, R. Berry III, Megan Rowe, Ali Winters, Shaohua Yang, Nicole Phillips

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Petrology and petrogenesis of a tuff layer in the Upper Red Formation, north of Tabriz (NW Iran): shoshonitic magmatism with high Ba and Sr affinity by Morovvat Faridazad, Nasser Ashrafi

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Neurological aspects of COVID-19. Management of patients with neurological diseases considering epidemiological situation by E. G. Demianovskaia, S. M. Kryzhanovskiy, A. S. Vasiliev, V. I. Shmirev

“…Structure of virion SARS-CoV-2 determine possible affinity for a number of receptors expressed on the neuronal membrane; viral proteins or genetic material were found in the nervous tissue. …”
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