Causal associations between 17 common autoimmune diseases and aortic diseases: a Mendelian randomization study by Dongliang Chen, Shengchen Liu, Jian Li, Yueyun Zhou, Tong Jing, Aizeretiaili Maimaiti, Fuhua Huang

“…Background: Previous studies have identified correlations between autoimmune and aortic diseases; however, the causal connection between these conditions remains uncertain and lack of comprehensiveness. …”
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Cross ethnic Mendelian randomization analysis reveals causal relationship between air pollution and risk of kidney stones by Shuangping Li, Aijia Mu, Zhinan Jing, Ziyi Liu, Xinfang Cao, Jincheng Guo, Yujia Xi, Qiang Guo

“…Additionally, the MVMR result revealed the directly causative connection between a single PM2.5 absorbance and the increase in kidney stone risk (OR = 1.77, 95%CI: 1.06–2.98, p = 0.03). …”
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Optimizing Circuit Reusing and its Application in Randomized Benchmarking by Zhuo Chen, Guoding Liu, Xiongfeng Ma

“…We establish a theoretical framework connecting the variance of experimental estimators with the reusing times $R$. …”
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The effects of coagulation factors on the risk of lung cancer: a Mendelian randomization study by Heran Zhou, Xinye Mao, Junhua Guo, Xuefei Yang, Ting Huang

“…Bidirectional two sample MR analyses were performed using genome-wide significant single nucleotide polymorphisms (SNPs) as instrumental variables. …”
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The Influence of Protecting Leadership Voices from Below Behaviour on the Digital Transformation of Insurance Firms in Kenya by John Odindo, Kepha Njenga, George K’aol

“…This study, grounded in adaptive leadership framework, adopted a positivist approach and a descriptive research design to study a target population of 392 supervisors from the 56 registered insurance firms listed by the Insurance Regulatory Authority. The final sample of 127 respondents, represented a response rate of 63%, was drawn using a stratified random sampling technique. …”
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Unraveling the causal relationship and underlying mechanisms between cathepsins on liver cancer: findings from mendelian randomization and bioinformatics analysis by Xiaoxue Wang, Zexin Zhu

“…Nonetheless, there have been limited clinical trials examining the connection between cathepsins and PLC. Therefore, we conducted a two-sample Mendelian randomization (MR) study to evaluate the causal relationship between cathepsins and PLC. …”
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The Effectiveness of a Positive Intervention Program Based on the Components of Resilience and Forgiveness in Autonomy and Emotional Processing in Victims Students by Shahrooz Nemati, rahim badri gargari, Yousef Adib, Sepideh Kazemi

“…The research population included all male and female students being victims of bullying in second secondary schools in Bostan Abad, Iran in the academic year of 2023-2024. A sample of 30 students were selected using the convenience sampling method and were. randomly assigned into experimental and control groups. …”
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Bidirectional Mendelian randomization study of the relationship between brain imaging-derived phenotypes and obstructive sleep apnea by ZHANG Huihua, GAN Jing, HOU Miaomiao, LU Na

“…Genetically determined reduced risk of OSA was associated with a resting-state functional connectivity characteristic (IVW β=-0.10, 95%CI -0.19‒-0.01, P=0.025), representing the functional connectivity strength between the bilateral frontal poles and the right frontal-parietal cortex. …”
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Interleukin-4 and specific IgE to oranges levels study in persons with allergic anamnesis by A. S. Prilutskiy, N. B. Abylgazinova, K. Y. Tkachenko

“…Currently allergic diseases pose a global health concern. The connection between immunoglobulin E antibodies (IgE-Ab) and allergic disorders is well established. …”
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Nicotine-induced changes in surface properties of restorative materials and dental enamel: An in vitro study on flavored e-cigarette exposure by Maria Salem Ibrahim, Fatimah M. Alatiyyah, Abdulsalam M. Alsalman, Rayan F. Alzenidi, Ali A. Albattat, Ahmed S. Alkhaldi

“…Methods The study utilized nanohybrid packable resin composite restorations, resin-modified glass ionomer (RMGI), and dental enamel samples (n=10). These samples were exposed to electronic cigarettes with different nicotine concentrations (3, 20, or 50 mg) using a customized chamber connected to a vacuum machine. …”
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Appraising the causal effects of circulating micronutrients on liver cirrhosis: Evidence from large‐scale Mendelian randomization analysis by Junlong Lin, Jialin Chen, Zhichao Li, Baifeng Qian, Yunpeng Hua

“…However, the lack of randomized controlled experiments has impeded the ability to establish a cause‐and‐effect connection regarding micronutrients and cirrhosis of the liver. …”
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Association between chronic kidney disease and colorectal cancer: evidence from meta-analysis and Mendelian randomization by Shuyi Qian, Yuting Gong, Ying Chen

“…This research utilized a meta-analysis of cohort studies along with two-sample Mendelian randomization (MR) approaches to explore the causal impact of CKD on CRC. …”
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Causal relationship between inflammatory cytokines and polycystic ovary syndrome: a bidirectional mendelian randomization study by Danling Tian, Jinfeng Chen, Liang Liu

“…We performed an interactive MR study to assess the causal relationships between 91 inflammatory cytokines and PCOS using Genome Wide Association Study (GWAS) data. We underwent dual-sample MR analysis with inverse variance weights (IVW) as the predominant MR methodology with multiple validity and heterogeneity analyses. …”
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Potential causal association between gut microbiota, inflammatory cytokines, and acute pancreatitis: A Mendelian randomization study by Xiaofeng Wang, Yiwen Qiu, Ying Di, Hou Shaohua, Wei Wu, Weiyi Wang, Huan Liu, Pu Li

“…Recent studies have increasingly emphasized the substantial connection among gut microbiota, inflammatory cytokines, and AP. …”
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Causal Effect of Obstructive Sleep Apnea on Sick Sinus Syndrome: A Bidirectional Mendelian Randomization Study by Chen W, Pan W, Ling L, Jiang B, Zhang Y, Su X, Jiang T, Lin J

“…This study aims to investigate the potential causal relationship between OSA and the development of SSS.Methods: To evaluate the association between OSA and SSS, we utilized a bidirectional two-sample Mendelian randomization (MR) method. Genetic variant OSA association data were sourced from FinnGens genome-wide association studies, comprising 410,385 individuals, while SSS association data were obtained from deCODE genetics, involving a dataset of 1, 000,187 individuals. …”
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Integrative multi-omics investigation of sleep apnea: gut microbiome metabolomics, proteomics and phenome-wide association study by Shuxu Wei, Ronghuai Shen, Xiaojia Lu, Xinyi Li, Lingbin He, Youti Zhang, Xianxi Huang, Zhouwu Shu

“…C–C motif chemokine 28 showed causal relationships in both directions (forward IVW, P = 0.0336; reverse IVW, P = 0.0336). Intermediate connections were found between the Holdemanella genus and urinary plasminogen activator levels with SA. …”
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The gut microbiota and diabetic nephropathy: an observational study review and bidirectional Mendelian randomization study by Yi Zhen Han, Yang Zhi Yuan Wang, Xing Yu Zhu, Bo Xuan Du, Yao Xian Wang, Xue Qin Zhang, Jia Meng Jia, Wei Jing Liu, Hui Juan Zheng

“…We verified the possible connection between certain genetically modified genera and DN, thereby emphasizing the connection between the “gut-kidney” axis and new insights into the GM’s role in DN pathogenesis underlying DN. …”
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Experimental inconsistencies undermine accurate characterization of microplastics and identification of environmental drivers:a metadata analysis in Chinese aquatic environment by Qinwei Chen, Peng Wang, Ru Liu, Mingjun Ding, Hua Zhang, Gaoxiang Huang, Minghua Nie

“…The abundance of microplastics was found to be significantly influenced by both human activities and natural processes, including farmland areas, landscape connectivity and annual mean precipitation. Furthermore, significant variations in the characteristics of microplastics were observed between experimental treatments, with the sampling method identified as a key factor influencing their observed abundance. …”
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Genetically predicted plasma metabolites mediate the causal relationship between gut microbiota and osteosarcoma by Xiuyu Qin, Zhuming Fan, Shaopeng Qiao, Jian Li, Jia Lv

“…Abstract Previous research has demonstrated a close connection between the development of osteosarcoma (OS) and variations in the abundance of specific gut microbiota (GM). …”
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Serum vitamin C levels and risk of osteoporosis: results from a cross-sectional study and Mendelian randomization analysis by Zhiwen Liu, Zijing Peng, Yelin Zhong, Jianjun Wu, Sicheng Xiong, Wei Zhong, Jiehua Luo, Zhihai Zhang, Hongxing Huang

“…This suggests the need for further investigation into the connection between vitamin C and bone health.…”
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