Music-induced cognitive change and whole-brain network flexibility: a pilot study by E. Lydia Wu-Chung, Melia E. Bonomo, Anthony K. Brandt, Bryan T. Denny, Christof Karmonik, Christof Karmonik, J. Todd Frazier, Karl Blench, Christopher P. Fagundes, Christopher P. Fagundes, Christopher P. Fagundes, Christopher P. Fagundes

“…Music engagement utilizes multiple brain regions dually involved in higher cognitive functions. Yet the neurobiology of music-induced cognitive change remains understudied. …”
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Proteins of the SubB family provide multiple mechanisms of serum resistance in Yersinia pestis by François Pierre, Alexandre Baillez, Amélie Dewitte, Agustin Rolandelli, Florent Sebbane

“…Altogether, the data suggest that at least two members of the SubB protein family function as virulence factors, conferring resistance to serum complement through a unique mode of action.…”
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Provisional measures’ application in custody hearings: a study based on homeless people’ arrests. by Vinícius de Assis Romão

“…Data collection took place at the Núcleo de Prisão em Flagrante e Audiências de Custódia in Salvador, in two periods of the year 2018, to understand the meanings conferred by judges, prosecutors and defenders regarding provisional measures in kind. …”
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The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation. by Philippe A Hasgall, David Hoogewijs, Marius B Faza, Vikram G Panse, Roland H Wenger, Gieri Camenisch

“…Although HELZ interacted with the poly(A)-binding protein (PABP) via its PAM2 motif, PABP was dispensable for HELZ function in protein translation. Importantly, downregulation of HELZ reduced translational initiation, resulting in the disassembly of polysomes, in a reduction of cell proliferation and hypophosphorylation of ribosomal protein S6.…”
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Th17 Cells Are More Protective Than Th1 Cells Against the Intracellular Parasite Trypanosoma cruzi. by Catherine W Cai, Jennifer R Blase, Xiuli Zhang, Christopher S Eickhoff, Daniel F Hoft

“…However, Th17 cells are not believed to have a significant function against intracellular infections. In contrast to this paradigm, we have discovered that Th17 cells provide robust protection against Trypanosoma cruzi, the intracellular protozoan parasite that causes Chagas disease. …”
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ATRX modulates the escape from a telomere crisis. by Helene E B Geiller, Adam Harvey, Rhiannon E Jones, Julia W Grimstead, Kez Cleal, Eric A Hendrickson, Duncan M Baird

“…Telomerase activity is the principal telomere maintenance mechanism in human cancers, however 15% of cancers utilise a recombination-based mechanism referred to as alternative lengthening of telomeres (ALT) that leads to long and heterogenous telomere length distributions. Loss-of-function mutations in the Alpha Thalassemia/Mental Retardation Syndrome X-Linked (ATRX) gene are frequently found in ALT cancers. …”
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CLINICAL COURSE, LONG–TERM EFFECTS AND OUTCOMES HEPATITIS A IN CHILDREN by V.F. Uchaikin, T.V. Cherednichenko, O.B. Kovalev

“…Hepatitis A is usually a self' limiting disease and infection confers lifelong immunity. However, the hepatitis A has of great clinical importance in children. …”
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ClpB chaperone as a promising target for antimicrobial therapy: A narrative review by Sachini J. Udari, Sayoka Shamodhi, Rumesh M. Nelumdeniya, Udayana Ranatunga, Nimesha N. Senadeera, Chathuranga B. Ranaweera

“…This review explores the function of ClpB in the survival of ESKAPE pathogens and the protozoan Plasmodium falciparum. …”
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Complement Activation: An Emerging Player in the Pathogenesis of Cardiovascular Disease by Angela M. Carter

“…An increasing body of evidence supports a functional role for complement activation in the pathogenesis of CVD through pleiotropic effects on endothelial and haematopoietic cell function and haemostasis. …”
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Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase. by Iker Lamas, Laura Merlini, Aleksandar Vještica, Vincent Vincenzetti, Sophie G Martin

“…We conclude that scaffold-mediated positive feedback, gated by Ras activity, confers robust polarization for rod-shape formation.…”
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The Sesquiterpenes(E)-ß-Farnesene and (E)-α-Bergamotene Quench Ozone but Fail to Protect the Wild Tobacco Nicotiana attenuata from Ozone, UVB, and Drought Stresses. by Evan C Palmer-Young, Daniel Veit, Jonathan Gershenzon, Meredith C Schuman

“…Although the sesquiterpenes (E)-ß-farnesene and (E)-α-bergamotene might confer benefits under intermittent heat stress, which was not tested, any roles in relieving abiotic stress may be secondary to their previously demonstrated functions in biotic interactions.…”
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The mre11 A470 alleles influence the hereditability and the segregation of telosomes in Saccharomyces cerevisiae. by In-Joon Baek, Daniel S Moss, Arthur J Lustig

“…MRE11 strains confer a telomere size of 300 base pairs of G+T irregular simple sequence repeats. …”
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Neurobiology Youth Follow-up Study: protocol to establish a longitudinal and prospective research database using multimodal assessments for current and past mental health treatment... by Daniel F Hermens, Sharon L Naismith, Adam J Guastella, Jan Scott, Elizabeth M Scott, Ian B Hickie, Frank Iorfino, Chloe Wilson, Alissa Nichles, Natalia Zmicerevska, Cathrin Rohleder, Yun Ju Christine Song, Joanne Sarah Carpenter, Blake Hamilton, Dagmar Koethe, F Markus Leweke, Catherine McHugh, Jacob Crouse, Nicholas Ho, Naomi Wray, Kathleen R Merikangas

“…This article describes the protocol for setting up a large-scale database that will collect longitudinal, prospective data that incorporate clinical, social and occupational function, neuropsychological, circadian, metabolic, family history and genetic metrics. …”
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4E10-resistant HIV-1 isolated from four subjects with rare membrane-proximal external region polymorphisms. by Kyle J Nakamura, Johannes S Gach, Laura Jones, Katherine Semrau, Jan Walter, Frederic Bibollet-Ruche, Julie M Decker, Laura Heath, William D Decker, Moses Sinkala, Chipepo Kankasa, Donald Thea, James Mullins, Louise Kuhn, Michael B Zwick, Grace M Aldrovandi

“…Naturally occurring Env variants described in our study also represent unique tools for probing the structure-function of HIV-1 envelope.…”
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Electric field stimulation directs target-specific axon regeneration and partial restoration of vision after optic nerve crush injury. by Timothy Kim, Ege Iseri, Micalla G Peng, Sasha Medvidovic, Timothy Silliman, Pooyan Pahlavan, Gengle Niu, Connie Huang, Anahit Simonyan, Javad Pahnahad, Petcy Yao, Phillip Lam, Vahini Garimella, Mahnaz Shahidi, Michael S Bienkowski, Darrin J Lee, Biju Thomas, Gianluca Lazzi, Kimberly K Gokoffski

“…In addition to partial anatomical restoration, ACB waveforms conferred partial restoration of visual function as measured by pattern electroretinogram recordings and local field potential recordings in the superior colliculus-and did so without the need for genetic manipulation. …”
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Understanding the mechanisms of a combined physical and psychological intervention for people with neurogenic claudication: protocol for a causal mediation analysis of the BOOST tr... by Sarah Lamb, Hopin Lee, Esther Williamson, Christine Comer

“…The primary mechanism of interest is walking capacity, and secondary mediators include fear-avoidance behaviour, walking self-efficacy, physical function, physical activity and/or symptom severity. …”
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TENDINopathy Severity Assessment-Achilles: a study protocol for cross-cultural adaptation and psychometric properties patient-reported outcome instrument in Persian athletes with A... by Bahram Sheikhi, Hadi Akbari

“…Findings from this study will be disseminated to the athletes, clinicians and researchers through peer-reviewed journals and national and international conferences.…”
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Quantifying the fitness advantage of polymerase substitutions in Influenza A/H7N9 viruses during adaptation to humans. by Judith M Fonville, David F Burke, Nicola S Lewis, Leah C Katzelnick, Colin A Russell

“…We use a mathematical model of within-host virus evolution to estimate the fitness advantage required for a substitution to reach predominance in a single infection as a function of the duration of infection and the fraction of mutant present in the virus population that initially infects a human. …”
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Borrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity. by Adam S Coleman, Xiuli Yang, Manish Kumar, Xinyue Zhang, Kamoltip Promnares, Deborah Shroder, Melisha R Kenedy, John F Anderson, Darrin R Akins, Utpal Pal

“…Together, these results suggest that the function of a selectively expressed B. burgdorferi gene, BbCRASP-2, is not essential for complement resistance or infectivity in the murine host.…”
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Effects of flexi-bar training on muscle strength and physical performance in older people with dynapenia: the protocol of a randomised controlled trial by Xinxin Wang, Ning Wei, Mengyu Lyu

“…This study will investigate the effects of a 12-week flexi-bar training programme on muscle strength and physical function in older people with dynapenia.Methods and analysis A total of 114 participants (aged more than 65 years) with age-related muscle loss will participate in a 12-week flexi-bar training programme. …”
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