Investigating the Role of BAFF and Its Receptors in Renal Transplant Recipients with Chronic Antibody-Mediated Rejection by Shima Afzali, Saeedeh Salehi, Abbas Shahi, Marzie Esmaeili, Samad Farashi Bonab, Azin Peykari, Farzaneh Bagherpour, Bita Ansaripour, Tayebeh Soleimanian, Fatemeh Pour-Reza-Gholi, Aliakbar Amirzargar

“…Due to their roles in B cell function, we intended to evaluate the B cell activating factor (BAFF) and its receptors including BAFF receptor (BAFF-R), B cell maturation antigen (BCMA), and transmembrane activator and cyclophilin ligand interactor (TACI) in renal transplant patients. …”
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Endoscopic variceal ligation combined with carvedilol versus endoscopic variceal ligation combined with propranolol for the treatment of oesophageal variceal bleeding in cirrhosis:... by Jing Wang, Meng Li, Lei Wang, Li Zhang, Ling Yang, Jian Wang, Duolao Wang, Rong Wang, Ya Peng, Chao Ma, Yiling Li, Yi Chen, Jing Xu, Xiaolong Qi, Hua Ye, Zhendong Jin, Hongyun Zhao, Wei Yan, Liwei Zhang, Chuan Liu, Andres Cardenas, Li Du, Ying Song, Biao Xie, Zhi Wei, Jianzhou Li, Wenhui Zhang, Qinghua Pan, Huiling Xiang, Shaoting Zhang, Shuairan Zhang, Xuan Liang, Shengjuan Hu, Lijun Peng, Xiaojie Zhang, Jingyi Xu, Xiaochao Liu, Huanhai Xu, Zhixu Fan, Lichun Shao, Pengyuan He, Qianlong Li, Yunhai Wu, Liyao Zhang, Dianliang Fang, Quanke Li, Dongli Xia, Yuchen Lv, Zongchao Zhang, Chaoguang Yan, Yuxia Wan, Haiming Fang, Wenlong Yang, Xiangman Zhang, Wei Rao, Xiurong Xia, Qiang Qiao, Ruimiao Yu, Changzhen Ren, Yuejun Yang, Zhenzhen Zhai, Xuejin Liu, Xingjun Lu, Yansheng Jia

“…The findings of this trial will be disseminated through peer-reviewed publications, conference presentations and healthcare professionals to guide future clinical practice.Trial registration number Chinese Clinical Trial Registry (Registration number: ChiCTR2400089692).…”
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An ABC transporter-mediated transport and metabolism of the pesticide bentazone in rice (Oryza sativa L.) by Yuxin Qiao, Yujue Wang, Yucheng Gu, Nan Zhang, Hong Yang, Jintong Liu

“…Methods: We established the rice transgenic lines overexpressing (OE) a rice OsABC transporter and its knockout lines by CRISPR-Cas9 to characterize the gene function and measured the accumulation of BNTZ residues in rice. …”
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Integrative anticoagulation of nafamostat mesylate in double plasma molecular adsorption system plus sequential half-dose plasmapheresis for patients with liver failure: a randomis... by Lang Bai, Ling Zhang, Fang Wang, Yingying Yang, Juan Liao, Zhiwen Chen, Xiankun Sun

“…The secondary outcomes include liver function indicators, extracorporeal circulation pressures, coagulation function parameters, all-cause mortality rates and survival rates. …”
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Polygenic prediction of human longevity on the supposition of pervasive pleiotropy by M. Reza Jabalameli, Jhih-Rong Lin, Quanwei Zhang, Zhen Wang, Joydeep Mitra, Nha Nguyen, Tina Gao, Mark Khusidman, Sanish Sathyan, Gil Atzmon, Sofiya Milman, Jan Vijg, Nir Barzilai, Zhengdong D. Zhang

“…Leveraging the genetic correlation between aging-related traits (ARTs), we aimed to model the additive variance in lifespan as a function of the cumulative liability from pleiotropic segregating variants. …”
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Identification and Partial Characterization of an L-Tyrosine Aminotransferase (TAT) from Arabidopsis thaliana by Pranav R. Prabhu, André O. Hudson

“…In vivo analysis by functional complementation showed that the gene was able to complement an E. coli with a background of aminotransferase mutations that confers auxotrophy for L-Tyrosine and L-Phenylalanine.…”
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Clinical effectiveness and cost-effectiveness of the rehabilitation enablement in chronic heart failure facilitated self-care rehabilitation intervention for people with heart fail... by John G F Cleland, Kate Jolly, Christi Deaton, Louise Taylor, Rod S Taylor, Aynsley Cowie, Alex McConnachie, Julia Frost, Colin Greaves, Chim C Lang, Emma McIntosh, Valerie Smith, Samantha van Beurden, Patrick J Doherty, Hasnain M Dalal, Tracy Ibbotson, Melvyn Hillsdon, Anna Placzek, Jessica C Bollen, Iain Squire, Emma Burrell, Nick Hartshorne-Evans, Elizabeth A Thomson, Claire O’Hare, Katie Dudman, Heather Fraser, Mohammad Jarallah

“…Introduction Heart failure with preserved ejection fraction (HFpEF) is common and causes functional limitation, poor health-related quality of life (HRQoL) and impairs prognosis. …”
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An efficient bivalent vaccine against duck Tembusu and duck plague viruses based on ribosomal skipping of DHAV-1 2A1 and abundant expression of DPV protein by Liping Wu, Xuewen Deng, Mingshu Wang, Anchun Cheng

“…In summary, the use of the DHAV-1 2A1 ribosomal skip function for the expression of exogenous proteins is feasible. …”
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Lung Health of Early COPD (LHEC): A Multi-Center Cohort Study—Rational and Design by Li W, Lei J, Li B, Tang X, Peng Y, Huang K, Yang T

“…By setting a narrower range of lung function thresholds to define pre- and mild-COPD, this study will effectively observe the early disease progression of COPD patients in a shorter period of time. …”
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Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation... by Daren K Heyland, Andrew Day, G John Clarke, Catherine (Terri) Hough, D Clark Files, Marina Mourtzakis, Nicolaas Deutz, Dale M Needham, Renee Stapleton

“…Introduction Survivors of critical illness often experience significant morbidities, including muscle weakness and impairments in physical functioning. This muscle weakness is associated with longer duration mechanical ventilation, greater hospital costs and increased postdischarge impairments in physical function, quality of life and survival. …”
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Harnessing Exosomes: A Brief Overview of Nature’s Nanocarriers and a Glimpse into Their Implications in Pituitary Neuroendocrine Tumors (PitNETs) by Ligia Gabriela Tataranu

“…Besides the general overview of exosomes as nature’s nanocarriers and their functions, this article aims to discuss their implications in PitNETs, especially since there have been many recent studies regarding the clinical benefits of biomolecular medicine.…”
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The Impact of Immunosenescence on Pulmonary Disease by Michelle A. Murray, Sanjay H. Chotirmall

“…Key facets of advancing age include genomic instability, telomere shortening, epigenetic changes, and declines in immune function termed immunosenescence. Immunosenescence and its associated chronic low grade systemic “inflamm-aging” contribute to the development and progression of pulmonary disease in older individuals. …”
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Experimental testing of a modified active disturbance rejection control for microphonics reduction in a 9-cell TESLA superconducting cavity by A. Elejaga, J. Jugo, P. Echevarria, A. Neumann, A. Ushakov, J. Knobloch

“…To begin with, a theoretical design of the controller based on an experimental transfer function of the cavity is carried out and its performance is compared with that of a proportional integral control. …”
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Emerging roles for E3 ubiquitin ligases in neural development and disease by Maya Hale, Greg J. Bashaw

“…In addition, a deeper understanding of the molecular mechanisms of E3 ligase function in development promises to offer new insights into the pathogenesis of neurodevelopmental disorders.…”
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Dissemination of Scientific Knowledge through Libraries in African Countries by L. K. Kurmysheva

“…The library, as one of the leading cultural institutions, takes on this function and implements it through its work with readers. …”
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Genome-wide identification, expression profile and selection analysis of the CPK gene family in Nelumbo nucifera by Teng Cheng, Mengyang Li, Chufeng Zhao, Tao Wang, Xingwen Zheng, Liangbo Yang, Ying Diao, Sai Yang, Zhongli Hu

“…It is responsive to environmental stress. Calcium functions as a ubiquitous second messenger in various signal transduction pathways in plants. …”
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Tubulointerstitial Biomarkers for Diabetic Nephropathy by Bancha Satirapoj

“…Recently, certain biomarkers, which were initially identified in acute kidney injury, also have been reported to confer value in evaluating patients with chronic kidney disease. …”
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Parboiled Rice and Glycemic Control: Effects on Postprandial Glucose, Insulin Sensitivity, and Incretin Response in Healthy and Type 2 Diabetic Individuals, a Pilot Study by Sara Alkandari, Tasleem A. Zafar, Suleiman Al-Sabah, Mohammed Abu Farha, Jehad Abubaker, Fahd Al-Mulla

“…Nevertheless, the impact of PBR consumption on insulin sensitivity, β-cell function, and incretin hormone responses remains poorly understood. …”
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Home-based mobile-guided exercise-based cardiac rehabilitation among patients undergoing transcatheter aortic valve replacement (REHAB-TAVR): protocol for a randomised clinical tri... by Ying Lin, Wenzhi Pan, Yuxia Zhang, Daxin Zhou, Zhiyun Shen, Shouling Mi, Chenxu Huang, Xiaohua Xu

“…The secondary outcomes include the 6-min walk distance at month 6, physical function measured by total Short Physical Performance Battery score and exercise adherence measured by the Exercise Adherence Rating Scale at months 3 and 6. …”
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Modeling Overall Survival in Patients With Pancreatic Cancer From a Pooled Analysis of Phase II Trials by Eva Rahman Kabir, Faruque Azam, Tanisha Tabassum Sayka Khan, Hasina Yasmin, Namara Mariam Chowdhury, Syeda Maliha Ahmed, Baejid Hossain Sagar, Nasrin Ahmed Tahrim

“…Moreover, gamma GLM (log‐link function) is a robust tool for modeling positively skewed survival data with non‐constant variance, thus can be applied to other cancers' OS data of such nature.…”
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