Liposomal Lactoferrin Reduces Brain Neuroinflammation in Rats and Alleviates Jetlag and Improves Sleep Quality After Long-Haul Travel by Shoko Uesaki, Masanori Yamato, Atsushi Ishikado, Yutaka Suekawa, Yasuhisa Tamura, Yosky Kataoka

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Impact of resistance exercise rehabilitation and whey protein supplementation in elderly patients with heart failure with preserved ejection fraction with sarcopenia: a study proto... by Rui Li, Hong Jiang, Yan Gao, Yi Chen, Mo Zhou, Yuhao Wei, Meishan Lu, Jieren Xi, Zhizhou Lin, Xiaoyun Zheng

“…HFpEF and sarcopenia can interact with each other and contribute to reduced physiological function and increased mortality in elderly patients. …”
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Association of pregnancy complications/risk factors with the development of future long-term health conditions in women: overarching protocol for umbrella reviews by Richard Riley, Shakila Thangaratinam, Kelvin Okoth, Holly Hope, Francesca Crowe, Siang Ing Lee, Jemma Healey, Mairead Black, Ngawai Moss, Katherine Phillips, Kelly-Ann Eastwood, Kathryn Mary Abel, Steven Wambua, Megha Singh, Neil Cockburn, Zoe Vowles

“…Findings will be disseminated through publications in peer-reviewed journals and conference presentations.…”
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An inner membrane complex protein IMC1g in Plasmodium berghei is involved in asexual stage schizogony and parasite transmission by Yinjie Liu, Shitong Cheng, Gang He, Dawei He, Duo Wang, Sicong Wang, Lumeng Chen, Liying Zhu, Yonghui Feng, Liwang Cui, Yaming Cao, Xiaotong Zhu

“…ABSTRACT The inner membrane complex (IMC), a double-membrane organelle underneath the plasma membrane in apicomplexan parasites, plays a significant role in motility and invasion and confers shape to the cell. We characterized the function of PbIMC1g, a component of the IMC1 family member in Plasmodium berghei. …”
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Edaravone dexborneol provides neuroprotective benefits by suppressing ferroptosis in experimental intracerebral hemorrhage by Han Li, Xiang Li, Mingzhi Li, Wenxin Li, Jinghui Wei, Yuming Huang, Haiqing Yan, Juntang Lin, Ping Zhang

“…This study aimed to evaluate the function and mechanism of EDB in treatment of ICH. …”
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The Church in the Camouflage of Mass Housing Construction. The Ecumenical Centre of Scharnhorst-Ost in Dortmund by Anna Kloke

“…Located in the densely populated industrial region of western Germany, the Scharnhorst-Ost Ecumenical Centre is an example of the important social and urban function of parish centres, especially in the newly built social housing estates of the post-war period. …”
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Feasibility and cross-cultural validation of an adapted social skills group training programme (KONTAKTTM CHILD) for Chinese autistic children: a waitlist RCT protocol by Sven Bölte, Peipei Yin, Uchong Lao, Huilin Zhu, Fengjing Liang, Wuxia Bai, Xiaoqian Huang, Sonya Girdler, Xiaobing Zou

“…Other outcomes include parents and teachers’ reports of participants’ autistic traits and adaptive functioning, participants’ self-report and projective tests for self-assertiveness and psychosocial functioning, and parent reports on parental reflective functioning and perceived school support. …”
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Global Grin2a loss causes divergent impairments to PV+ and SST+ interneurons and alters gamma oscillations in prefrontal cortex by Hassan Hosseini, Sky Evans-Martin, Kevin S. Jones

“…Background: Loss-of-function mutations in the Grin2a gene, encoding the GluN2A subunit of NMDA receptors, confer elevated schizophrenia (SCZ) risk. …”
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Study protocol of a randomised controlled trial of the effects of near-infrared spectroscopy neurofeedback training coupled with virtual reality technology in children with ADHD by Que Zheng, Kathy Tsam-ling Kei, Ka Yu Chiu, Kathy Kar-man Shum

“…Primary outcomes will include measures of executive function, such as attentional control, response inhibition and working memory, along with changes in oxygenated and deoxygenated haemoglobin levels monitored by functional NIRS. …”
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Early versus delayed mobilisation for non-surgically treated proximal humerus fractures: a systematic review and meta-analysis of randomised trials by Dimitris Challoumas, Haroon Minhas, Stephanie Bagni, Neal Millar

“…Conclusions Our meta-analysis of RCTs showed that commencement of mobilisation within one week from injury for non-surgically managed PHFs is safe and may confer short-term functional benefits compared to delayed mobilisation.…”
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Comparative effectiveness of non-pharmacological therapies for postoperative cognitive dysfunction: Protocol for a systematic review and network meta-analysis. by Kexin Wu, Qiongnan Bao, Jun Huang, Shanshan Sun, Yaqin Li, Xinyue Zhang, Manze Xia, Zhenghong Chen, Jin Yao, Wanqi Zhong, Zihan Yin, Fanrong Liang

“…The primary outcome will be the changes in the overall cognitive function before and after the intervention. The secondary outcome will be the incidence of POCD. …”
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Surgical considerations towards inducing proprioceptive feedback in dental implants by Siddhartha Das, Subhashis Ghosh, Qisheng Tu, Zoe Xiaofang Zhu, Jake Jinkun Chen

“…Abstract Periodontal ligament (PDL) consists mainly of collagen fiber bundles with specialized mechanoreceptors and free nerve endings that connect the cementum of the tooth root to alveolar bone and are vital for dental proprioceptive function. When a tooth is lost and replaced with a dental implant, osseointegration occurs without the intervening PDL, leading to a loss of proprioceptive function. …”
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Territorial Spatial Governance for High-Quality Urban Agglomerations Development: Insights from the Yangtze River Delta and Guangdong-Hong Kong-Macao Greater Bay Area by Yue Wenze, Xia Haoxuan, Zhang Xianchun

“…These include transcending administrative barriers; improving the regional performance assessment system, territorial spatial planning and use control system, and joint conference system; optimizing the spatial layout, ensuring food security in urban agglomerations, enhancing the efficiency of urban development, implementing the strategy of main functional areas, strengthening the management of ecological space, and enhancing the territorial spatial resilience of urban agglomerations; and promoting the flow of elements by referring to innovative policies such as the enclave economy mode, the linkage management of land-use plans, and comprehensive land consolidation.…”
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Biochemical and Computational Analysis of the Substrate Specificities of Cfr and RlmN Methyltransferases. by Eleni Ntokou, Lykke Haastrup Hansen, Jacob Kongsted, Birte Vester

“…Almost all replacements showed no function in the primer extension assay, apart from a few that had a weak effect. …”
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Beijing Longitudinal Disability Survey in Community Elderly (BLINDSCE): protocol for a community-based prospective longitudinal cohort study about disability prediction model by Yue Wu, Shaoyuan Lei, Siqi Cheng, Xinyan Du, ChengBei Hou, Hongjun Liu, Xiaolin Yue, Yansu Guo

“…Disability is assessed using the WHO’s Disability Assessment Schedule 2.0, activities of daily living, the Barthel index, locomotor function and physical function. Based on baseline cross-sectional information, the relationships between multiple factors and disability can be initially screened using logistic regression. …”
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Early warning and stratification of the elderly cardiopulmonary dysfunction-related diseases: multicentre prospective study protocol by Ping Wang, Min Zhou, Li Fan, Yi Xia, Ziwei Zhang, Zhiping Guo, Zaiyi Liu, Yang Hou, Xiuxiu Zhou, Qianxi Jin, Yu Guan, Chuanchang Li, Yongping Bai, Wei-Hua Liao, Hongyu Lin, Shiyuan Liu

“…To address this gap, this study protocol launched a project to build a clinical imaging technology integration and a multicentre database for early warning and stratification of cardiopulmonary dysfunction in the elderly.Methods and analysis This study employs a cross-sectional design, enrolling over 6000 elderly participants from five regions across China to evaluate cardiopulmonary function and related diseases. Based on clinical criteria, participants are categorized into three groups: a healthy cardiopulmonary function group, a functional decrease group and an established cardiopulmonary diseases group. …”
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The Evolution of the Neural Basic Helix-Loop-Helix Proteins by Michel Vervoort, Valerie Ledent

“…The proneural function of Drosophila bHLH genes may be an innovation that occurs in the evolutive lineage that leads to arthropods. …”
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Thalamic neural activity and epileptic network analysis using stereoelectroencephalography: a prospective study protocol by Takahiro Suzuki, Ryuta Saito, Tomotaka Ishizaki, Satoshi Maesawa, Shun Yamamoto, Miki Hashida, Yoshiki Ito, Takafumi Tanei

“…The thalamus plays a crucial role in coordinating neural networks, both in normal brain function and the propagation of epileptic activity. …”
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Role of selenium in the pathophysiology of cardiorenal anaemia syndrome by Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata

“…Selenium critically regulates the function of selenoproteins, in which selenocysteine is present at the active centres. …”
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The Hepatoprotective Properties of Gentiopicroside, Sweroside, and Swertiamarin Against Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) by Anthony O. Boateng, Vinood B. Patel, S. W. Annie Bligh

“…It was concluded that phytochemicals gentiopicroside, sweroside, and swertiamarin play key roles in the hepatocyte protection against the cytotoxic effects of fatty acids. This protection is conferred by enhancing mitochondrial function in terms of increasing the maximal respiratory capacity in response to a high influx of fatty acids, promoting ATP production as well as scavenging ROS produced as a result of high fatty acid influx and increased mitochondrial respiration. …”
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