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1301
Paediatric goal management training in patients with acquired brain injury: study protocol for a randomised controlled trial
Published 2019-08-01“…Furthermore, we aim to assess generalisation effects of pGMT on other cognitive functions, as well as emotional, behavioural, adaptive and family function, academic performance, fatigue and quality of life.Ethics and dissemination Results from this study will be disseminated to relevant research, clinical, health service and patient communities through publications in peer-reviewed and popular science journals, in addition to presentations at scientific conferences. …”
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1302
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1303
Concurrent Physical Activity Protects Against C26 Adenocarcinoma Tumor-Mediated Cardiac and Skeletal Muscle Dysfunction and Wasting in Males
Published 2025-06-01“…Exercise may help preserve muscle mass and function, yet the translatability of preclinical methods remains questionable. …”
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1304
Multidimensional pain profiling in people living with obesity and attending weight management services: a protocol for a longitudinal cohort study
Published 2022-12-01“…Obesity is associated with increased self-reported pain intensity and pain-related disability, reductions in physical functioning and poorer psychological well-being. People living with obesity tend to respond less well to pain treatments or management compared with people living without obesity. …”
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1305
Aerobic exercise protects against pressure overload-induced cardiac dysfunction and hypertrophy via β3-AR-nNOS-NO activation.
Published 2017-01-01“…Aerobic exercise confers sustainable protection against cardiac hypertrophy and heart failure (HF). …”
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1306
Health literacy interventions in adult speech and language therapy: A scoping review
Published 2024-02-01“…Most explored basic functional health literacy or narratively described core components of health literacy, which an SLT should understand, without employing an investigative research design. …”
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1307
Comprehensive and robust stability-indicating reversed phase high performance liquid chromatography (RP-HPLC) method for Rivaroxaban: synergistic integration of infrared spectrosco...
Published 2025-04-01“…A method has been developed and validated for its analysis, adhering to guidelines from the International Conference on Harmonisation (ICH) and the U.S. Pharmacopeia (USP). …”
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1308
Rapid evolution of virus sequences in intrinsically disordered protein regions.
Published 2014-12-01“…Thus, the function of an intrinsically unstructured protein region can be independent of most of its primary sequence, conferring both functional robustness and sequence plasticity on the protein. …”
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1309
Network features of the mammalian circadian clock.
Published 2009-03-01“…We also observed several examples where a gene is up-regulated following knockdown of its paralog, suggesting the clock network utilizes active compensatory mechanisms rather than simple redundancy to confer robustness and maintain function. We propose that these network features act in concert as a genetic buffering system to maintain clock function in the face of genetic and environmental perturbation.…”
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1310
Two-Component MprAB System Regulates the Expression of Genes Involved in Cell Envelope Biosynthesis in <i>Corynebacterium glutamicum</i>
Published 2025-05-01“…The results indicated that the MprAB TCS directly controls a broad regulon, including cell wall biosynthesis proteins, alternative sigma factors, secreted proteins of unknown function, and the <i>mprAB</i> gene locus itself. Among these, the HtrA-like serine protease confers vancomycin and penicillin resistance. …”
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1311
Examining the effects of creatine supplementation in augmenting adaptations to resistance training in patients with prostate cancer undergoing androgen deprivation therapy: a rando...
Published 2019-09-01“…Introduction Creatine supplementation has consistently been demonstrated to augment adaptations in body composition, muscle strength and physical function in a variety of apparently healthy older adults and clinical populations. …”
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1312
SCIENCE TEACHERS’ ICT USE FREQUENCY AND THE BARRIERS THEY WERE EXPOSED
Published 2014-07-01“…</p><p align="center"><strong>Extended Abstracts</strong><strong></strong></p><p><strong>Introduction</strong></p><p>Developments in ICTs effect construct and function of educational initiatives and institutions and in the same time, change the expectations of several sectors (e.g. economy, industry and communication) from educational institutions. …”
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1313
A phase II double-blind multicentre, placebo-controlled trial to assess the efficacy and safety of alpelisib (BYL719) in paediatric and adult patients with Megalencephaly-CApillary...
Published 2024-12-01“…Introduction The megalencephaly capillary malformation polymicrogyria (MCAP syndrome) results from mosaic gain-of-function PIK3CA variants. The main clinical features are macrocephaly, somatic overgrowth, neurodevelopmental delay and brain anomalies. …”
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1314
Agile development of a digital exposure treatment for youth with chronic musculoskeletal pain: protocol of a user-centred design approach and examination of feasibility and prelimi...
Published 2022-09-01“…Introduction Chronic pain affects a significant number of children and impacts multiple domains including social, emotional and behavioural functioning, and negatively impacts family functioning. …”
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1315
PCSK9-antibodies fail to block PCSK9-induced inflammation in macrophages and cannot recapitulate protective effects of PCSK9-deficiency in experimental myocardial infarction
Published 2025-01-01“…Despite its known effects on cholesterol metabolism, the role of PCSK9 in cardiac function, especially post-myocardial infarction (MI), remains unclear. …”
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1316
Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases
Published 2025-06-01“…Recent advancements, including germ‐free animal models, fecal microbiota transplantation (FMT), and diverse probiotic strains, have revealed the underlying mechanisms linking gut health to brain function. Notably, several Lactobacillus and Bifidobacterium species have been shown to exert neuroprotective effects via the upregulation of neurotrophic factors such as brain‐derived neurotrophic factor and enhancing mitochondrial function through reducing the impacts of oxidative stress. …”
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1317
Pelota: A double-edged sword in virus infection.
Published 2025-07-01“…Beyond its canonical role in maintaining translational fidelity via No-Go Decay and Non-Stop Decay pathways, Pelota exhibits a dual function during viral infection-serving either as a restriction factor or as a susceptibility element depending on the virus species and their hosts. …”
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1318
Special Issue on Contemporary Research Studies in Operations Research, Business Analytics, and Business Intelligence
Published 2025-06-01“…Optimization Algorithms: Developing efficient algorithms to solve linear fractional transshipment problem with multi-objective linear fractional functions. 4. AI in Business Intelligence: Investigating long-term impacts of AI-enabled Business Intelligence tools on data-driven decision-making and organizational performance. 5. …”
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1319
Vagus nerve stimulation in dementia: A scoping review of clinical and pre-clinical studies
Published 2024-09-01“…The main reported outcomes of VNS in the dementia cases were enhanced cognitive functions, an increased functional connectivity of various brain regions involved in learning and memory, microglial structural modifications from neurodestructive to neuroprotective configurations, a reduction of cerebral spinal fluid tau-proteins, and significant evoked brain tissue potentials that could be utilized to diagnose neurodegenerative disorders. …”
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1320
An In-Depth Examination of Phytochemicals and Medicinal Uses on <i>Morus alba</i>
Published 2024-12-01“…Morus alba's cardiovascular benefits include improved endothelial function and lipid metabolism. Its neuroprotective effects protect the brain from oxidative damage and neuroinflammation, supporting cognitive function. …”
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