Evaluation of eight-style Tai chi on cognitive function in patients with cognitive impairment of cerebral small vessel disease: study protocol for a randomised controlled trial by Bin Chen, Hong-Jia Zhao, Hui Liang, Rui Xia, Xiaoyong Zhong, Xinghui Yan

“…At the same time, fMRI and P300 will be measured the structure and function of brain regions related to cognitive function at baseline and 24 weeks after randomisation. …”
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Effects of traditional Chinese medicine massage therapy on pain, functional activity, muscle activation patterns and proprioception in knee osteoarthritis: a randomised controlled... by Xin Zhou, Cheng Tang, Bowen Zhu, Yangyang Fu, Min Fang, Sitong Fang, Qingguang Zhu, Yuen Yee Janice Hiew

“…Secondary outcomes include knee function (measured using the WOMAC stiffness and WOMAC functional subscale questionnaire and the timed ‘Up and Go’ test), muscle activation states (evaluated with electromyography techniques), knee proprioception and treatment satisfaction, adherence, safety evaluation and other relevant factors. …”
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A Review of the Nutritional Profile, Chemical Composition and Potential Health Benefits of Aronia melanocarpa (Chokeberry) Berries and Products by Ayşe Semra Aksoy

“…The abundant presence of polyphenols, such as phenolic acids, flavonols, anthocyanins, flavanols, and proanthocyanidins, plays a crucial role in conferring the remarkable bioactivity of chokeberries. …”
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Pain, gastrointestinal function and fertility outcomes of modified nerve‐vessel sparing segmental and full thickness discoid resection for deep colorectal endometriosis – A prospec... by Gernot Hudelist, Daria Pashkunova, Ezgi Darici, Anna Rath, Johanna Mitrowitz, Bernhard Dauser, Birgit Senft, Attila Bokor

“…Conclusions NVSSR and FTDR for symptomatic colorectal DE confer a significant amelioration of GI function reflected by decreased LARS symptoms and increased GIQLI scores with no differences in postsurgical function in between the two techniques. …”
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DEcreased Cognitive functiON, NEurovascular CorrelaTes and myocardial changes in women with a history of pre-eclampsia (DECONNECT): research protocol for a cross-sectional pilot st... by Marc E A Spaanderman, Chahinda Ghossein-Doha, Sander MJ van Kuijk, Gwyneth Jansen, Walter H Backes, Emma B N J Janssen, Yentl Brandt, Robert-Jan Alers, Lisanne P W Canjels, Laura M Jorissen, Tamara Michelle Went, Dennis Koehn, Suzanne C Gerretsen, Petra P M Hurks, Vincent van de Ven, M Eline Kooi, Jacobus FA Jansen

“…This study will explore differences in cerebral and myocardial microvascular function between women after pre-eclampsia and women after normotensive gestation. …”
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How does the intensity of physical therapy affect the Gross Motor Function Measure (GMFM-66) total score in children with cerebral palsy? A systematic review protocol by Mary Rahlin, Burris Duncan, Carol L Howe, Heidi L Pottinger

“…Many studies use the Gross Motor Function Measure (GMFM-66) to assess functional progress in children with CP. …”
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Assessing the feasibility and impact of specially adapted exercise interventions, aimed at improving the multi-dimensional health and functional capacity of frail geriatric hospita... by Carolyn A Greig, Paul Doody, Janet M Lord, Anna C Whittaker

“…The findings will be disseminated through publication in open access scientific journals, public engagement events, online via social media, conference presentations and directly to study participants on request.Trial registration number NCT03141866…”
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Effect of extracorporeal shock wave combined with Kinesio taping on upper limb function during individuals with biceps brachii tendinopathy：protocol for a double-blind, randomised... by Ye Zhang, Kun Liu, Yanhong Ma, Ran Zhu, Ping Fang, Lihua Huang, Zheng Ma, Lulu Yin, Gongliang Liu

“…In addition to international conference reports, findings will be disseminated through international publications in peer-reviewed journals.Trial registration number ChiCTR2100051324.…”
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RESTORE—Cognitive functional therapy with or without movement sensor biofeedback versus usual care for chronic, disabling low back pain: study protocol for a randomised controlled... by Alison H McGregor, Mark Hancock, Peter Kent, P O'Sullivan, Anne Smith, Terry Haines, Amity Campbell, Jan Hartvigsen, Kieran O'Sullivan, Alistair Vickery, JP Caneiro, Robert Schütze, Robert A Laird, Stephanie Attwell

“…Recent evidence suggests that individualised cognitive and movement rehabilitation combined with lifestyle advice (cognitive functional therapy (CFT)) may produce larger and more sustained effects than traditional approaches, and movement sensor biofeedback may enhance outcomes. …”
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Molecular mechanisms of drug resistance and compensation in SARS-CoV-2 main protease: the interplay between E166 and L50 by Sarah N. Zvornicanin, Ala M. Shaqra, Julia Flynn, Heidi Carias Martinez, Weiping Jia, Stephanie Moquin, Dustin Dovala, Daniel N. Bolon, Nese Kurt Yilmaz, Celia A. Schiffer

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TaCIPK19-3D Improves Photosynthetic Machinery, Growth, Yield, and Salt Tolerance in Transgenic Rice by Muhammad Arif, Dingli Hong, Ruhong Xu, Mo Xian Chen, Hafiz Mamoon Rehman, Zhongni Wang, Luhua Li

“…In this study, we characterized the function of TaCIPK19-3D through overexpression in transgenic rice and CRISPR-Cas9-mediated oscipk19 knockout lines. …”
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CoronaVac-induced antibodies that facilitate Fc-mediated neutrophil phagocytosis track with COVID-19 disease resolution by Chuang Li, Jie Yu, Rahma Issa, Lili Wang, Mingzhe Ning, Shengxia Yin, Jie Li, Chao Wu, Yuxin Chen

“…To fully define the potential immune correlates of Fc-mediated effector functions, we comprehensively analysed the above Fc-mediated effector functions in two study cohorts. …”
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Unveiling the Biological Properties of <i>Rosa rubiginosa</i> L. Leaf Extract as a Bio-Functional Ingredient Based on 2D Cell-Based Models and In Vitro Assessments by Sophia Letsiou, Aliki Tsakni, Dionysis Antonopoulos, Alexandros Tsoupras, Dimitra Houhoula

“…This study explores its diverse bioactivity on human primary keratinocytes and fibroblasts, highlighting its potential as a bio-functional agent in cosmeceuticals or nutraceuticals. …”
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Arthroscopic Latarjet combined with remplissage and capsulolabral repair in the treatment of anterior shoulder instability—the quadruple effect. A prospective study of functional o... by Ayyappan V. Nair, DOrtho, DNB, MNAMS, Bharath Bharadwaj M S, MS Ortho, DNB(Ortho), Maythilisharan Rambhojan, MS Ortho, Sreejith Thampy J, MS Ortho, Aravind Rajan, MS Ortho, DNB ORTHO, Kiran V, MS Ortho, MRCS (Edinburgh), Prince Shanavas Khan, DOrtho, MS Ortho

“…Though an external rotation deficit was observed, when compared to the opposite shoulder, the patients did not have any functional deficits in performing daily activities. …”
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Protocol for a prospective cohort study on the feasibility of application of nutritional ultrasound in the diagnosis and follow-up of patients with nutritional risk at hospital dis... by Gabriel Olveira, Daniel de Luis, José Manuel García Almeida, Diego Bellido, Germán Guzmán Rolo

“…The results from this study will be presented at scientific conferences and in peer-reviewed scientific journals.Trial registration number NCT05433831.…”
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Effects of repetitive transcranial magnetic stimulation over the contralesional dorsal premotor cortex on upper limb function in severe ischaemic stroke: study protocol for a rando... by Xi Yang, Yi Zhu, Tong Wang, Ying Shen, Lu Fang, Wenjun Dai, Canhuan Liu, Hongyuan Ding, Chuan Guo, Manyu Dong, Yilun Qian

“…The secondary outcomes include the Arm Subscore of the Motricity Index, Hong Kong edition of Functional Test for the Hemiplegic Upper Extremity, Modified Barthel Index and Modified Ashworth Scale score of the paralysed pectoralis major and biceps brachii. …”
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Mediating role of gut microbiota on Baduanjin for cognitive function in community-dwelling older adults with mild cognitive impairment: a study protocol for a cluster randomised co... by Guohua Zheng, Liwei Sun, Qian Geng

“…Introduction The gut microbiome plays an important role in maintaining both cognitive and physical functions in older adults, and gut dysbiosis is an important pathophysiological mechanism of mild cognitive impairment (MCI) in older adults. …”
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hUMSC-Exosomes suppress TREM1-p38 MAPK signaling via HMGB1-dependent mechanisms to reprogram microglial function and promote neuroprotection in ischemic stroke by Zengyu Zhang, Rong Ji, Zhuohang Liu, Zhiwen Jiang, Min Chu, Yong Wang, Jing Zhao

“…By delivering HMGB1, hUMSC-Exos inhibit TREM1-dependent NF-κB/p38 activation, reprogram microglial function, and confer neuroprotection. Validated across in vivo, primary, and BV2 microglial models, and supported by multi-omics analyses, this study establishes hUMSC-Exos as a promising cell-free therapy targeting microglial reprogramming for ischemic stroke recovery. …”
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Using functional near-infrared spectroscopy to study effects of virtual reality intervention for adolescents with depression in a clinical setting in China: study protocol for a pr... by Yan Zhang, Lijun Wang, Dongsheng Zhou, Xiaofang Ye, Kunqiang Yu, Shaochang Wu, Shiqiao Lv, Linhui Liu, Xiuxiu Zheng, Ruomei Jin, Guoqing Min

“…In addition, patients randomised to VR treatment group (n=33) will complete three 20 min VR sessions including attention, executive function and relaxation training per week. Moreover, 33 healthy adolescents will be recruited as the general population. …”
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Morin Flavonoid Interaction with Albumin and Its Nanoparticle Conjugation: An Efficient Antioxidant Vehicle for Nutraceuticals by Guillermo Montero, Víctor Guarnizo-Herrero, Catalina Sandoval-Altamirano, Germán Günther, Soledad Bollo, Francisco Arriagada, Javier Morales

“…These findings support BSA–morin nanoparticles as a promising system for the oral delivery and functional food incorporation of polyphenolic antioxidants.…”
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