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Transcription termination and antitermination are critical for the fitness and function of the integrative and conjugative element Tn916.
Published 2024-12-01“…We identified a transcription terminator near one end of Tn916 that functions as an insulator that prevents expression of element genes when Tn916 is integrated downstream from an active host promoter. …”
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282
PI3-kinase has multiple functions in asexual blood stages of Plasmodium falciparum
Published 2025-05-01“…Here we dissect the functions of PfPI3-kinase by inducible deletion of its gene using the loxP-DiCre system and find that PfPI3-kinase is essential for parasite survival. …”
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283
Molecular cloning and functional identification of an apple flagellin receptor MdFLS2 gene
Published 2018-12-01“…Furthermore, the ectopic expression of MdFLS2 complemented the function of the Arabidopsis fls2 mutant and conferred enhanced flg22 tolerance to the transgenic Arabidopsis, suggesting that MdFLS2 acts as a positive regulator in the response to pathogens in apple.…”
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284
BrWax1 function in wax biosynthesis was verified by allelic mutations in Chinese cabbage
Published 2025-05-01“…The primary function of cuticular wax is to prevent non-stomatal water loss, while the wax deficiency conferring a glossy appearance on plants is conductive to crop commodity qualities. …”
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285
Exogenous Ubiquitin Differentially Modulates the Phenotype and Function of M1 and M2 Macrophages
Published 2025-06-01“…Exogenous ubiquitin (eUB) is shown to decrease inflammatory response and confer cardioprotection in mice 3 days post-ischemia/reperfusion (I/R) injury. …”
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286
The active site of a carbohydrate esterase displays divergent catalytic and noncatalytic binding functions.
Published 2009-03-01“…Multifunctional proteins, which play a critical role in many biological processes, have typically evolved through the recruitment of different domains that have the required functional diversity. Thus the different activities displayed by these proteins are mediated by spatially distinct domains, consistent with the specific chemical requirements of each activity. …”
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Objective Functions for the Blade Shape Optimisation of a Cross-Flow Tidal Turbine under Constraints
Published 2025-06-01Get full text
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290
Investigation of the gas-sensing performance of CuO sensors functionalized with different stabilized Au nanoparticles
Published 2025-03-01“…The CuO/Cu<span class="inline-formula"><sub>2</sub></span>O films are functionalized with sodium citrate and also with synthesized Au nanoparticles (Au NPs), which are stabilized with different types of ligands, namely, <span class="inline-formula"><i>α</i></span>-methoxypoly(ethylene glycol)-<span class="inline-formula"><i>ω</i></span>-(11-mercaptoundecanoate) (PEG–MUA), 3-mercaptopropionic acid (MPA), and citrate. …”
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291
Multimorbidity patterns and function among adults in low- and middle-income countries: a scoping review
Published 2025-01-01“…Objectives To map the scope of available evidence on relationships between multimorbidity patterns and functioning among adults in low- and middle-income countries (LMICs), and describe methods used.Design Scoping review guided by a five-step methodological framework and Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews reporting guidelines.Data sources PubMed/MEDLINE, Scopus, EBSCOhost (CINAHL) and Cochrane databases were searched from January 1976 to March 2023, plus reference lists of included studies.Eligibility criteria for selecting studies Peer-reviewed full-text articles or conference proceedings of any design, published in English or Afrikaans, involving adults (>18 years) with multimorbidity living in LMICs. …”
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A preimage attack on reduced GIMLI‐HASH with unbalanced squeezing phase
Published 2023-01-01“…Abstract In Conference on Cryptographic Hardware and Embedded System 2017, Bernstein et al. proposed GIMLI, a 384‐bit permutation with 24 rounds, which aims to provide high performance on various platforms. …”
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295
Contributions of mirror-image hair cell orientation to mouse otolith organ and zebrafish neuromast function
Published 2024-11-01“…These results clarify how molecular mechanisms that confer bi-directionality to sensory organs contribute to function, from single hair cell physiology to animal behavior.…”
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296
Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
Published 2024-12-01“…Moreover, we report copper sequestration by neuroblastoma attenuates neutrophil function which can be successfully reversed using copper chelation to increase pro-inflammatory effector functions. …”
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297
Functional polymorphism of the mu-opioid receptor gene (OPRM1) influences reinforcement learning in humans.
Published 2011-01-01“…Previous reports on the functional effects (i.e., gain or loss of function), and phenotypic outcomes (e.g., changes in addiction vulnerability and stress response) of a commonly occurring functional single nucleotide polymorphism (SNP) of the mu-opioid receptor (OPRM1 A118G) have been inconsistent. …”
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298
Functional link between mitochondria and Rnr3, the minor catalytic subunit of yeast ribonucleotide reductase
Published 2019-05-01“…Together, these results unveil involvement of Rnr3 in mitochondrial functions and Mec1 in mediating the carbon source dependent regulation of Rnr3.…”
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299
Influence of Bilberry Pomace Powder Addition on the Physicochemical, Functional, Rheological, and Sensory Properties of Stirred Yogurt
Published 2024-09-01“…The present study was conducted to develop a novel functional yogurt by adding bilberry pomace powder (BPP) at 0.5%, 1.0%, and 1.5% (<i>w</i>/<i>w</i>) levels in stirred-type yogurt production to confer color and to increase the dietary fiber and polyphenol content. …”
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Association of Interleukin-1α Functional Polymorphism with Risk of Chronic Periodontitis in Han Chinese Population
Published 2021-01-01“…Genetic factors are thought to play important roles in its onset and development. A functional polymorphism (rs1800587) in the promoter of the interleukin-1α gene (−889 C/T) has been found to confer risk of CP primarily in Europeans, but the association between this variant and CP in the Chinese population remains less conclusive. …”
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