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    Design and evaluation of novel triazole derivatives as potential anti-gout inhibitors: a comprehensive molecular modeling study by Mohammed Er-rajy, Mohammed Er-rajy, Mohamed El fadili, Sara Zarougui, Somdutt Mujwar, Mourad Aloui, Mohammed Zerrouk, Belkheir Hammouti, Larbi Rhazi, Rachid Sabbahi, Mohammed M. Alanazi, Khalil Azzaoui, Khalil Azzaoui, Rachid Salghi, Menana Elhallaoui

    Published 2025-03-01
    “…A computational study was carried out to identify the xanthine oxidase inhibitory structural features of a series of triazole inhibitors using computational method.ResultsA model based on CoMFA and CoMSIA/SEA has been built to predict new triazole derivatives.DiscussionThe optimal model established from CoMFA and CoMSIA/SEA was successfully evaluated for its predictive capability. …”
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