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Ubiquitous memory augmentation via mobile multimodal embedding system
Published 2025-06-01Get full text
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Systems metabolic engineering of Corynebacterium glutamicum for efficient l-tryptophan production
Published 2025-06-01“…This study presents a comprehensive metabolic engineering approach to establish robust C. glutamicum strains for l-tryptophan biosynthesis, including: (1) identification of potential targets by enzyme-constrained genome-scale modeling; (2) enhancement of the l-tryptophan biosynthetic pathway; (3) reconfiguration of central metabolic pathways; (4) identification of metabolic bottlenecks through comparative metabolome analysis; (5) engineering of the transport system, shikimate pathway, and precursor supply; and (6) repression of competing pathways and iterative optimization of key targets. …”
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The Combination of Pairwise and Group Interactions Promotes Consensus in Opinion Dynamics
Published 2021-01-01Get full text
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Improving neural network training using dynamic learning rate schedule for PINNs and image classification
Published 2025-09-01Get full text
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Treatment of inoperable pancreatic adenocarcinoma with focused ultrasound and microbubbles in patients receiving chemotherapy
Published 2025-06-01“…Nine boluses of MBs were injected intravenously (i.v) with a 3.5 min interval. Patients were scheduled for two months of treatment. …”
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Investigation of the Effect of Dimple Bionic Nonsmooth Surface on Tire Antihydroplaning
Published 2015-01-01Get full text
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Rational Design for Improving the Thermostability of Saccharomyces cerevisiae Nicotinamide Riboside Kinase 1
Published 2024-12-01“…The results showed that after two rounds of mutagenesis, a mutant named T136P/S209A with significantly improved thermal stability and catalytic activity was obtained. Its optimal reaction temperature was increased to 45 ℃, and its half-life at 45 ℃ was 48.98 min, which was 4.2 times as high as that of the wild-type ScNRK1. …”
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