Enhanced genome editing with a Streptococcus equinus Cas9 by Jingtong Liu, Yao Wang, Jingjing Wei, Shengzhou Wang, Miaomiao Li, Zheyong Huang, Sufang Zhang, Huihui Liu, Jinhai Huang, Yongming Wang

“…Abstract A large number of SpCas9 orthologs has been computationally identified, but their genome editing potential remains largely unknown. …”
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Complete O α s 2 $$ \mathcal{O}\left({\alpha}_s^2\right) $$ corrections to the leptonic invariant mass spectrum in b → X c l ν ¯ l $$ b\to {X}_cl{\overline{\nu}}_l $$ decay by Mateusz Czaja, Mikołaj Misiak, Abdur Rehman

“…We present our results in terms of numerical fits in both the single- and triple-charm cases. We confirm the recently found results for the single-charm correction, and analyze the triple-charm channel impact on centralized moments of the spectrum.…”
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Impact of Wave COVID-19 Responses on Black Carbon Air Pollution in Moscow Megacity Background by Olga B. Popovicheva, Marina A. Chichaeva, Roman G. Kovach, Ekaterina Yu. Zhdanova, Victor M. Stepanenko, Alexander Varentsov, Nikolay S. Kasimov

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Surgical Strategy in Patients with Complete Transposition of Internal Organs in Cancer of the Biliopancreatoduodenal Zone by R. V. Ischenko, Yu. V. Ivanov, A. V. Smirnov, V. N. Antipov

“…Аim: to present two clinical cases of successful surgical treatment of patients with a combination of complete transposition of internal organs and cancer of the biliopancreatoduodenal zone.Key points. …”
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2014/15 Picking, Roadsiding, and Hauling Charges for Florida Citrus by Ariel Singerman

“…The fact sheet will assist growers in the effort to compute the changes to their economic returns as the industry adapts to remain profitable. …”
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Clinicoradiological Manifestations of Melioidosis with Pulmonary Involvement in a Tertiary Hospital Setup by P Prem Ananth, R Anand, R Prathipa, S Raghul Raj, N Nagarajan

“…The delay in diagnosis in these chronic cases is attributed to their atypical presentation often mimicking tuberculosis or malignancy. …”
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Synthetic CT generation from CBCT and MRI using StarGAN in the Pelvic Region by Paritt Wongtrakool, Chanon Puttanawarut, Pimolpun Changkaew, Supakiet Piasanthia, Pareena Earwong, Nauljun Stansook, Suphalak Khachonkham

“…Abstract Rationale and objectives This study evaluated StarGAN, a deep learning model designed to generate synthetic computed tomography (sCT) images from magnetic resonance imaging (MRI) and cone-beam computed tomography (CBCT) data using a single model. …”
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A mathematical model of mechanotransduction by Bradley J. Roth

“…A one-dimensional example illustrates the model, which is then extended to two or three dimensions. In a few cases, the bidomain equations can be solved analytically, demonstrating how tissue motion can be divided into two parts: monodomain displacements that are the same in both spaces and therefore do not contribute to mechanotransduction, and bidomain displacements that cause mechanotransduction. …”
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En plaque meningioma of the temporal bone: A systematic review on the imaging and management of a rare tumor by Arianna Burato, Giuseppe Maruccio, Livio Presutti, Ignacio Javier Fernandez, Gabriele Molteni, Giulia Molinari

“…Objective: To review the published cases of meningioma en plaque of the temporal bone (TB-MEP), to gather evidence on the clinical assessment and management of this rare entity. …”
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Ontology-based expansion of virtual gene panels to improve diagnostic efficiency for rare genetic diseases by Jaemoon Shin, Toyofumi Fujiwara, Hirotomo Saitsu, Atsuko Yamaguchi

“…We also performed computational experiments on an evaluation dataset comprising 74 patients to determine the optimal VGP design method. …”
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Using Internet of Things for Child Care: A Systematic Review by Saeed Saeedbakhsh, Maryam Mohammadi, Sarina Younesi, Mohammad Sattari

“…Articles not meeting criteria were excluded. Finally, 29 cases had the necessary criteria to enter this study. …”
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Tolerability and efficacy of Mycobacterium avium complex pulmonary disease treatment in elderly patients by Kyota Shinfuku, Hiromichi Hara, Keitaro Okuda, Hanae Miyagawa, Naoki Takasaka, Takeo Ishikawa, Jun Araya

“…Treatment efficacy of the two-drug regimen was non-inferior, and no cases of macrolide resistance were observed. Conclusions The two-drug regimen of EB and macrolide without RFP may be a tolerable and effective treatment for elderly MAC-PD patients.…”
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Analysis of ADR reports of cetuximab based on the FDA adverse event reporting system database by Shuai Zhao, Yan Wang, Xiaoli Deng, Xi Chen, Zhaoyi Lu

“…This study retrospectively analyzed the cases reported in the FDA adverse event reporting system (FAERS) related to the application of cetuximab from 2013 Q1 to 2022 Q4. …”
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Multijunction solar cell parameter estimation based on metaheuristic algorithms by Marwa M. Elzalabani, Doaa M. Atia, Aref Y. Eliwa, Belal A. Abou Zalam, Mahmoud S. AbouOmar

“…The results demonstrate the superior performance of the AHA algorithm, which has the lowest RMSE value (0.0582) in the SDM and DDM cases, while WSA has the lowest RMSE value (0.0488) in the TDM instance. …”
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PROVIDING DISTANCE EDUCATION DURING THE WAR: THE EXPERIENCE OF UKRAINE by Lidia Londar, Marcus Pietsch

“…Even for students who are not affected by flight and displacement, learning opportunities in war zones can be limited because of newly dangerous circumstances. In such cases, distance education can offer students the opportunity to use distance learning technologies even under extremely difficult and challenging conditions and, in this way, contribute to a stable learning environment for students in times of war. …”
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Trabecular Bone Remodeling after Lateral Lumbar Interbody Fusion: Indirect Findings for Stress Transmission between Vertebrae after Spinal Fusion Surgery by Naoki Segi, Hiroaki Nakashima, Sadayuki Ito, Jun Ouchida, Ryotaro Oishi, Ippei Yamauchi, Yuichi Miyairi, Yoshinori Morita, Mikito Tsushima, Hiroyuki Tomita, Kazuaki Morishita, Kazuma Ohshima, Tokumi Kanemura, Shiro Imagama

“…Methods: A total of 53 cases who underwent one- or two-level LLIF with polyether ether ketone cage and posterior spinal fixation/fusion (PSF) were retrospectively included in this study. …”
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Fifth Lumbar Vertebral Shape in Early-Stage Lumbar Spondylolysis: Three-Dimensional Bone Morphology Analysis Using Homologous Models by Yuji Yamane, Hajime Toda, Masaki Katayose

“…However, there are no comprehensive examinations of the three-dimensional vertebral shape in early-stage cases. This study aimed to investigate the overall L5 vertebral shape in early-stage spondylolysis. …”
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Comparative Analysis of Biomarkers in Type 2 Diabetes Patients With and Without Comorbidities: Insights Into the Role of Hypertension and Cardiovascular Disease by Symeon Savvopoulos, Haralampos Hatzikirou, Herbert F Jelinek

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Hypnotics' association with mortality or cancer: a matched cohort study by Daniel F Kripke, Lawrence E Kline, Robert D Langer

“…Hazard ratios (HRs) for death were computed from Cox proportional hazards models controlled for risk factors and using up to 116 strata, which exactly matched cases and controls by 12 classes of comorbidity.Results As predicted, patients prescribed any hypnotic had substantially elevated hazards of dying compared to those prescribed no hypnotics. …”
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Exploring the role of ESR1 mutations in metastatic hormone receptor-positive breast cancer T cell immune surveillance disruption by Morgane Lopez, Laurie Spehner, Fabrice André, Julien Viot, Evan Seffar, Amélie Marguier, Elsa Curtit, Guillaume Meynard, Erion Dobi, Sylvain Ladoire, Romain Boidot, Romain Loyon, Valentin Derangere, François-Clément Bidard, Christophe Borg, Laura Mansi, Marie Kroemer

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