The Role of Diffusion-Tensor Magnetic Resonance Imaging and Tractography in the Diagnosis of Structural Brain Disorders in Children with Cerebral Palsy by Yu. V. Ermolina, L. S. Namazova-Baranova, A. M. Mamedyarov, A. V. Anikin, O. I. Maslova

“…Using diffusion-tensor magnetic resonance imaging and tractography, it became possible to conduct comprehensive structural and functional studies, to study the main stages of the brain maturation in dynamics, and to compare the morphological data with peculiarities of psycho-verbal and motor development of a child, as well as to conduct clinical and neuroimaging comparison. …”
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Protein lactylation of citrate synthase promotes the AKI-CKD transition by activating the NLRP3 inflammasome by Fang Yu, Yan Meng, Xiaoyue Wang, Jia Chen, Junling He, Xiangling Yi, Yani He, Kehong Chen

“…Notably, the rate-limiting enzyme citrate synthase (CS) exhibits significantly elevated lactylation levels post-AKI induction, and K370 was the most significant lysine residue. …”
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A Novel One-Stop Multidisciplinary Clinic for Chronic Postoperative Inguinal Pain: Initial Experiences and Outcomes by Federica Cocciolo, Alice Birch, Maciej Pawlak, Lucy Miller, Alan Bennett, Matthew Lund, David Sanders, John M. Findlay, John M. Findlay, John M. Findlay

“…BackgroundChronic Postoperative Inguinal Pain (CPIP) affects 10%–20% of patients following inguinal hernia repair, persisting for over 3 months post-surgery. It involves a complex interplay of neuropathic and nociceptive pain, secondary sensitization, and functional and psychological impacts. …”
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Congenital infection with Plasmodium malariae: a rare case of intrauterine transmission in Germany by Sarah Goretzki, Nora Bruns, Anna Daniels, Anne Schönecker, Adela Della Marina, Andrea Gangfuß, Bernd Schweiger, Andreas Schönfeld, Oliver Witzke, Jutta Dedy, Jan Dziobaka, Caroline Holtkamp, Peter-Michael Rath, Ursula Felderhoff-Müser, Christian Dohna-Schwake, Hedda-Luise Verhasselt

“…Following treatment with intravenous artesunate and oral atovaquone/proguanil, the infant showed significant improvement and was discharged after 36 days (22 days of paediatric intensive care) with a multidisciplinary follow-up plan. At six months post-discharge, she demonstrated stable organ function and mild developmental delay. …”
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Effect of diabetes mellitus on spinal cord high signal relief after anterior cervical spine surgery in patients with cervical spondylotic myelopathy by Zichuan Wu, Xuhong Zhang, Hanlin Song, Aochen Xu, Baifeng Sun, Chen Xu, Min Qi, Yang Liu

“…Our analysis reveals that although preoperative HbA1c levels did not significantly impact outcomes at six months post-surgery (Table2 and Table4), maintaining low HbA1c levels was associated with considerable improvements in both spinal cord high signal (HCS) and neurological function at two years postoperatively (Table3 and Table5). …”
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An artificial intelligence-based platform for personalized predictions of Metacognitive Training effectiveness by Caroline König, Pedro Copado, Alfredo Vellido, Àngela Nebot, Cecilio Angulo, Maria Lamarca, Vanessa Acuña, Fabrice Berna, Steffen Moritz, Łukasz Gawęda, Susana Ochoa

“…The platform is meant to function as an experimental prototype in the scope of a clinical research project for a decision support system to assist clinicians in tailoring treatment plans for patients with psychosis. …”
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Multi-Domain Environmental Quality of Indoor Mixed-Use Open Spaces and Insights into Healthy Living—A Quarantine Hotel Case Study by Han Wang, Wenjian Pan

“…In the post-pandemic context, data-driven design interventions that can endow architectural spaces with mixed-use and open characteristics that are adaptable and environmentally resilient are increasingly important. …”
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Ataxin-2: a powerful RNA-binding protein by Lulu Li, Meng Wang, Lai Huang, Xiaoli Zheng, Lina Wang, Hongming Miao

“…The impact of ATXN2 on diseases extends beyond functional outcomes; it mainly interacts with various RNA-binding proteins (RBPs) to regulate different stages of post-transcriptional gene expression in diseases. …”
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Influence of Sulfur Fumigation on Angelicae Dahuricae Radix: Insights from Chemical Profiles, MALDI-MSI and Anti-Inflammatory Activities by Changshun Wang, Yongli Liu, Xiaolei Wang, Zhenhe Chen, Zhenxia Zhao, Huizhu Sun, Jian Su, Ding Zhao

“…These findings provide a chemical basis for comprehensive safety and functional evaluations of sulfur-fumigated ADR, supporting further research in this field.…”
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EVALUATION OF THE PSYCHOSOCIAL IMPACT OF DENTAL AESTHETICS BY SOCIODEMOGRAPHICS AND MALOCCLUSIONS by Kalender Muhammed Emin, Ucan Yarkac Fatma, Emiroglu Yunus

“…These results align with previous studies but expand understanding by including a wider age range and malocclusion analysis.Conclusion: Dental aesthetics deeply influence self-confidence and social interactions, emphasizing the importance of addressing these concerns for both functional and psychological reasons. Further research should examine pre- and post-treatment effects to provide comprehensive insights. …”
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Failure Analysis of Fire in Lithium-Ion Battery-Powered Heating Insoles: Case Study by Rong Yuan, Sylvia Jin, Glen Stevick

“…This study investigates a lithium-ion battery failure in heating insoles that ignited during normal walking while powered off. Through comprehensive material characterization, electrical testing, thermal analysis, and mechanical gait simulation, we systematically excluded electrical or thermal abuse as failure causes. …”
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An Observational Study on Pre-natal Diagnosis of Congenital Talipes Equinovarus by Gaurav Vatsa, Saurabh Suman, Siddharth Kumar Singh

“…Future research should assess long-term functional outcomes and optimize pre-natal screening protocols, particularly in resource-limited settings, to ensure comprehensive CTEV management.…”
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IFIT2-induced transcriptomic changes in Mycobacterium tuberculosis infected macrophages by Ewura-Esi Manful, Ray-Dean Pietersen, Bienyameen Baker

“…Using a vector-based overexpression approach, IFIT2 expression was induced in THP-1 cells infected with R179 M. tb, followed by RNA extraction 12 hours post-infection and AmpliSeq-based targeted transcriptome sequencing. …”
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Cell fate acquisition and reprogramming by the proneural transcription factor ASCL1 by Jethro Lundie-Brown, Francesca Puletti, Anna Philpott, Roberta Azzarelli

“…By integrating these perspectives, this review provides a comprehensive overview of the diverse roles of ASCL1 in development, reprogramming and cancer, offering insights into its molecular functions and therapeutic potential.…”
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Exploring the role of gut probiotic metabolites in the prevention and treatment of otitis media by Bo Zheng, Haiyong Jin

“…PPI interaction was used to identify the 10 hub targets. To understand the post-transcriptional regulation of these common genes, we identified miRNAs targeting them using the multiMiRR package.ResultsThe functional enrichment and disease association analyses of these genes and miRNAs revealed their significant involvement in inflammatory and immune regulatory pathways, many of which are shared with chronic otitis media pathogenesis.DiscussionOverall, this integrative approach established a strong link between gut microbial metabolites, their host gene targets, and miRNA-mediated regulatory mechanisms in otitis media. …”
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Integrative glycomic analysis reveals the crucial role of protein glycosylation in fungal pathogenesis. by Heeji Moon, Eun Jung Thak, Yejin Choi, Sieun Kim, Jiyeun Park, Nahyun Lee, Soobin Shin, Hosung Jeon, Jessica Winarto, Soyoung Choi, Ji Young Shin, Jung-Eun Kim, Dae-Geun Song, Hun Kim, Gyung Ja Choi, Hyun Ah Kang, Hokyoung Son

“…Protein glycosylation, a co- and post-translational modification that enhances the functional diversity of the proteome, contributes to various molecular and cellular functions by transferring different polysaccharides onto proteins. …”
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Effectiveness of Pain Neuroscience Education in Physical Therapy: A Systematic Review and Meta-Analysis by Andrea Sánchez-Robalino, Hugo Sinchi-Sinchi, Andrés Ramírez

“…<b>Results</b>: The findings indicate that PNE combined with physical therapy significantly reduces pain intensity and enhances functionality. The mean pain score decreased from 5.89 (pre-intervention) to 3.03 (post-intervention), with similar improvements observed in disability outcomes. …”
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Genome-wide identification and characterization of the bZIP family in the Mangrove Plant Kandelia obovata and its role in response to stress by Yuchong Yi, Yuting Qiu, Hongyao Hu, Dandan Qin, Hechen Huang, Taiping Chen, Wenqi Zha, Yingjia Shen

“…This study aims to provide a comprehensive characterization of the bZIP gene family in K. obovata and investigate its functional roles in response to environmental stresses. …”
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Impact of a Digital Platform for Wildlife Information Management in the Cerro Blanco Protected Forest of Guayaquil Using Plithogenic Statistics by Sonia Jacqueline Tigua Moreira, Edison Luis Cruz Navarrete, Diana Lucia Tigua Moreira, Pedro Manuel García Arias

“…The results indicate a highly significant positive sentiment from users toward the post-application functionality and the standardization of faunal resources. …”
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Hybrid Grey–Fuzzy Approach for Optimizing Circular Quality Responses in Plasma Jet Manufacturing of Aluminum Alloy by Ivan Peko, Boris Crnokić, Jelena Čulić-Viskota, Tomislav Matić

“…In this paper, a comprehensive analysis regarding the machinability and optimal circular quality of aluminum alloy 5083 was performed. …”
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