Physiology and Pathophysiology of Marathon Running: A narrative Review by Lorin Braschler, Pantelis T. Nikolaidis, Mabliny Thuany, Daniela Chlíbková, Thomas Rosemann, Katja Weiss, Matthias Wilhelm, Beat Knechtle

“…Concerning lung function, a decrease after a marathon race was observed. …”
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Cumulative health burden and adjustment challenges following road traffic injuries: a controlled prospective study by Ilaria Pozzato, Yvonne Tran, Mohit Arora, Candice McBain, James W. Middleton, Ian D. Cameron, Ashley Craig

“…Conclusions RTIs lead to sustained, multidimensional challenges to adjustment, emphasizing the need for early, comprehensive, and ongoing interventions for at least 1-year post-injury. …”
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Advanced 4-chamber echocardiography techniques enable clinically matched precise characterization of heart disease progression in mice by Ege Kacira, Mariam F. Oueis, Nawal H. Tamimi, Sarah L. Sturgill, Xianyao Xu, Thomas J. Hund, Mark T. Ziolo, Yuchi Han, Isabelle Deschênes, Ji-dong Fu

“…Results: Here we show that LAX-BP echocardiography demonstrates volumetric accuracy comparable to cardiac magnetic resonance (CMR) and detects significant LV functional decline within the first week post-TAC–changes that are not clearly captured by M-mode imaging. …”
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Mental well‐being in prostate cancer: A multi‐institutional prospective cohort study by Oliver Brunckhorst, Jaroslaw Liszka, Callum James, Jack B. Fanshawe, Mohamed Hammadeh, Robert Thomas, Shahid Khan, Matin Sheriff, Gordon Muir, Hashim U. Ahmed, Mieke Van Hemelrijck, Robert Stewart, Prokar Dasgupta, Kamran Ahmed

“…Patient factors for poorer mental well‐being included younger age, a previous psychiatric history, social deprivation, poorer baseline mental health symptoms and poorer baseline sexual and urinary function. Symptom trajectory analysis demonstrated the increasing symptom load in body image and masculine self‐esteem experienced post any active treatment modality, with more stable scores for other mental well‐being measures. …”
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A differentiated approach to the surgical treatment of intraarticular fracture of the proximal tibia by A.V. Kalashnikov, Y.M. Litun, Ye.E. Chip, A.M. Syvak

“…The tactics of surgical treatment depended on the type of fracture, the age of the patients and the presence of concomitant diseases. A comprehensive assessment of knee function was performed using the Knee Society Score. …”
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Identification of potential pathogenic genes associated with the comorbidity of rheumatoid arthritis and renal fibrosis using bioinformatics and machine learning by Jiao Qiu, Yalin Xu, Luyuan Tong, Xingchun Yang, Xiao Wu

“…Gene set enrichment analysis (GSEA) clarified the potential biological pathways through which BIRC3 and PSMB9 might function in RF. The constructed miRNA-TF-mRNA regulatory network provided a comprehensive overview of the post-transcriptional and transcriptional regulatory mechanisms. …”
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Proximity‐dependent biotinylation reveals an interaction between ubiquitin‐specific peptidase 46 and centrosome‐related proteins by Kazuma Yoshioka, Reiko Nakagawa, Chi Lieu Kim Nguyen, Hayate Suzuki, Kiyohiro Ishigaki, Seiya Mizuno, Tsukasa Okiyoneda, Shizufumi Ebihara, Kazuya Murata

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Cell based high-throughput screening for small molecule inhibitors of ATE1 by Claudia McCown, Evan A. Ambrose, Devang M. Patel, Hassan Al-Ali, Louis Scampavia, Fangliang Zhang, Timothy P. Spicer

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Development and evaluation of a reproductive health promotion program for women of reproductive age with kidney transplant: protocol for a mixed methods study by Zohreh Haghighatdana, Fatemeh Mohammadi, Mohammad Saad Forghani, Shahnaz Kohan

“…A significant portion of the kidney transplant burden is related to the women’s reproductive function and potential. Kidney transplantation significantly improves the quality of life and survival of women with ESRD; thus, they are more inclined to resume fertility health care. …”
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Genome and Pathogenicity Analysis of an NADC30-like PRRSV Strain in China’s Xinjiang Province by Honghuan Li, Wei Zhang, Yanjie Qiao, Wenxing Wang, Wenxiang Zhang, Yueli Wang, Jihai Yi, Huan Zhang, Zhongchen Ma, Chuangfu Chen

“…Serum biochemical tests indicated significant impairment of liver and kidney function. PRRSV antibodies began to appear gradually after 10 days post infection. …”
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Signaling networks and MiRNA crosstalk in ovarian cancer chemoresistance by Raksha Nayak, Samyak Pandey, Dileep Kumar, Sachindra Kumar, K Sreedhara Ranganath Pai

“…The review provides a comprehensive overview of the molecular mechanisms driving chemoresistance, emphasising critical elements of signalling pathways and associated miRNAs that contribute to resistance and may function as biomarkers or therapeutic targets to mitigate chemoresistance. …”
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The role of psychosocial factors in mediating the treatment response of epidural steroid injections for low back pain with or without lumbosacral radiculopathy: A scoping review. by Meredith Stensland, Donald McGeary, Caleigh Covell, Elizabeth Fitzgerald, Mahsa Mojallal, Selena Lugosi, Luke Lehman, Zachary McCormick, Paul Nabity

“…Of the 51 included studies, only 10 (20%) analyzed and reported the relationship between at least one psychosocial variable and post-injection pain at any follow-up timepoint. The other 41 (80%) included no analyses examining ESI response as a function of psychosocial variables. …”
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Legal regulation of organization and provision of rehabilitation assistance to anti-terrorist operation/joint forces operation participants by O. D. Gavlovskyy

“…It has been established that there are no unified protocols for medical rehabilitation in Ukraine: only a protocol of measures for post-traumatic stress disorder has been developed. …”
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The Effect of High-Intensity Interval Training (HIIT) on Brain-Derived Neurotrophic Factor Levels (BNDF): A Systematic Review by Milosz Mielniczek, Tore Kristian Aune

“…Bias was evaluated using visualization tools such as RobVis, and the review was conducted by a single researcher, which may limit its comprehensiveness. Results: Twelve studies met the inclusion criteria, with most indicating significant increases in BDNF levels post-HIIT, suggesting HIIT’s potential to enhance neuroplasticity and cognitive functions. …”
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L-arginine Supplementation in Endurance Athletes: A Systematic Review of Recovery Mechanisms and Performance Enhancement by Łukasz Karoń, Anna Ewa Zygmunt, Karolina Karoń, Wojciech Grabowski, Grzegorz Drapała, Emilia Pedrycz, Daria Pedrycz

“…Recognized for its multifaceted roles in cardiovascular, immune, and metabolic functions, L-arginine serves as a precursor to biologically active molecules, including nitric oxide (NO), creatine, and polyamines, which are integral to muscle function and recovery. …”
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A current view of the issue of rehabilitation of patients with ocular pathology by S.V. Katsan, M.Yu. Morozova, O.S. Zadorozhnyy, N.V. Pasyechnikova

“…The following major aspects of further development of the vision rehabilitation system in Ukraine were determined: 1) organization of up-to-date process of rehabilitation in the field of healthcare requires forming specialty rehabilitation units/words for persons with visual impairments (PVAs); 2) a comprehensive and continuous process of rehabilitation for PVAs should be achieved through established relationships among the parties involved; 3) rehabilitation is not only for people whose visual impairment is permanent and irremediable, but is primarily for those whose visual impairment is potentially remediable; 4) increasing awareness of vision rehabilitation issues among ophthalmologists and rehabilitation specialists should be a strategic objective of the healthcare system; 5) rehabilitation of vision should not only involve measures for adaptation of low-vision patients to new life conditions, but also should consider a range of measures aimed at optimizing visual function, including postoperative rehabilitation, post-medication rehabilitation, surgical rehabilitation, esthetic rehabilitation (including prosthetics), etc, and 6) developing specialty rehabilitation care for PVIs and moving forward from empirical approaches to an era of evidence-based practice requires further research on the efficacy of measures of medical vision rehabilitation.…”
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Health Status After Total Hip Arthroplasty: A Literature Review by Mădălin Bulzan, Florica Voiță-Mekeres, Simona Cavalu, Gheorghe Szilagyi, Gabriel Mihai Mekeres, Lavinia Davidescu, Călin Tudor Hozan

“…An analysis of 67 studies reveals significant postoperative enhancements in physical function, pain alleviation, and overall patient satisfaction. …”
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Gut microbiota mediates the pro-pyroptosis effect of xierezhuyubuxu decoction in hepatocellular carcinoma by Zhili Zeng, Zhili Zeng, Zhili Zeng, Zhili Zeng, Mingxuan Feng, Fan He, Enxin Zhang, Xiushen Li, Zebiao Cao

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Dynamic Monitoring of Goaf Stress Field and Rock Deformation Driven by Optical Diber Sensing Technology by Jing Chai, Zhe Yan, Yibo Ouyang, Dingding Zhang, Jianfeng Yang, Gaoyi Yang, Chenyang Ma

“…By coupling the fracture mechanics model of the critical layer and the settlement trajectory function model, the dynamic transformation of the pre-fracture and post-fracture stages is realized, and the stress evolution can be monitored and predicted in real time. …”
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Blood–brain barrier disruption and neuroinflammation in the hippocampus of a cardiac arrest porcine model: Single-cell RNA sequencing analysis by Tangxing Jiang, Yaning Li, Hehui Liu, Yijun Sun, Huidan Zhang, Qirui Zhang, Shuyao Tang, Xu Niu, Han Du, Yinxia Yu, Hongwei Yue, Yunyun Guo, Yuguo Chen, Feng Xu

“…Our findings provide a comprehensive single-cell map of the post-cardiac arrest hippocampus, offering potential novel targets for neuroprotection and repair following cardiac arrest.…”
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