DMN network and neurocognitive changes associated with dissociative symptoms in major depressive disorder: a research protocol by Asli Ercan Dogan, Herdem Aslan Genc, Herdem Aslan Genc, Sinem Balaç, Sinem Balaç, Sevin Hun Senol, Görkem Ayas, Zafer Dogan, Emre Bora, Emre Bora, Deniz Ceylan, Deniz Ceylan, Deniz Ceylan, Deniz Ceylan, Vedat Şar

“…The primary objective of this study is to determine whether MDD patients with prominent dissociative symptoms differ from those without such symptoms in clinical presentation, neurocognitive performance, and markers of functional connectivity. This investigation will be the first to integrate comprehensive clinical evaluations, advanced neurocognitive testing, and high-resolution brain imaging to delineate the contribution of dissociative symptoms in MDD.MethodsWe will recruit fifty participants for each of three groups: (1) depressive patients with dissociative symptoms, (2) depressive patients without dissociative symptoms, and (3) healthy controls. …”
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Adaptive landscapes unveil the complex evolutionary path from sprawling to upright forelimb function and posture in mammals. by Robert J Brocklehurst, Magdalen Mercado, Kenneth D Angielczyk, Stephanie E Pierce

“…We shed new light on the origins of mammalian posture, using evolutionary adaptive landscapes to integrate 3D humerus shape and functional performance data across a taxonomically comprehensive sample of fossil synapsids and extant comparators. …”
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Multimodal Alzheimer’s disease classification through ensemble deep random vector functional link neural network by Pablo A. Henríquez, Nicolás Araya

“…Early detection, particularly among individuals at high risk, is critical for effective treatment or prevention, yet remains challenging due to data variability and incompleteness. Most current research relies on single data modalities, potentially limiting comprehensive staging of AD. …”
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RNA Binding Motif Protein 15 (RBM15): Structure, Function and Its Research Progress in Tumors by Long X, Hu B, Zhu S, Wu Y, Wang T

“…RBM15 is an important component of the methyltransferase complex. Although its functions are increasingly being recognized, a comprehensive overview of its critical roles in cancer regulation and potential therapeutic relevance is still lacking. …”
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Current situation of pharmacy services in community health centers and the functioning of pharmacists in family doctor teams in Shanghai by Rui LIU, Yu CAO, Aiqun CHU, Huanyun WU

“…Background: Currently, polypharmacy is common among residents at high risk of unsafe medication practices, partly due to a lack of medication reconciliation and comprehensive medication management. Pharmacy services, facilitated by community health centers with regional advantages, align with their functional orientation. …”
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Resting-state functional magnetic resonance imaging in bipolar affective disorder. A systematized umbrella review by K. V. Markin

“…Qualitative synthesis of results of nine systematic reviews and six meta-analyses has allowed the definition of changes in spontaneous activity and functional connectivity most characteristic for BD, confirming the unity of functional disturbances of this nosological unit. …”
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A role for transcription factor GTF2IRD2 in executive function in Williams-Beuren syndrome. by Melanie A Porter, Carol Dobson-Stone, John B J Kwok, Peter R Schofield, William Beckett, May Tassabehji

“…Executive functions are amongst the most heritable cognitive traits with twin studies indicating a strong genetic origin. …”
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Structural and functional imaging studies in chronic cannabis users: a systematic review of adolescent and adult findings. by Albert Batalla, Sagnik Bhattacharyya, Murat Yücel, Paolo Fusar-Poli, Jose Alexandre Crippa, Santiago Nogué, Marta Torrens, Jesús Pujol, Magí Farré, Rocio Martin-Santos

“…<h4>Background</h4>The growing concern about cannabis use, the most commonly used illicit drug worldwide, has led to a significant increase in the number of human studies using neuroimaging techniques to determine the effect of cannabis on brain structure and function. …”
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Radial Basis Function Coupling with Metaheuristic Algorithms for Estimating the Compressive Strength and Slump of High-Performance Concrete by Amir Reza Taghavi Khangah, Erfan Khajavi, Hasti Azizi, Amir Reza Alizade Novin

“…Compressive strength (CS) and slump flow (SL) are two of the most essential parameters in High-Performance Concrete (HPC), which directly affect its structural capacity, durability, and workability. …”
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Neuropsychological Function and the Relationship Between Subjective Cognition, Objective Cognition, and Symptoms in Hypermobile Ehlers–Danlos Syndrome by Amber Sousa, Min‐Kyung Jung, Arline Allera, Bernadette Riley

“…Very little research has directly examined the neuropsychological functioning profile in hEDS, but some research has found associations of hypermobility with cognitive difficulties, psychological symptoms, and structural brain differences. …”
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Cognitive Function Tests: Application of MMSE and MoCA in Various Clinical Settings- a Brief Overview by Piotr Oleksy, Karol Zieliński, Bartosz Buczkowski, Dominik Sikora, Ewa Góralczyk, Adam Zając, Magdalena Mąka, Łukasz Papież, Jakub Kamiński

“… Introduction:  Cognitive impairment can emerge as part of aging or from conditions affecting brain function, such as stroke, brain tumors, delirium, and neurodegenerative diseases. …”
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Complex Assessment of the Functional State of the Urinary System in Preclinical Studies. Part 2. Markers of Nephrotoxicity (Review) by M. V. Miroshnikov, K. T. Sultanova, M. N. Makarova, N. M. Faustova, S. O. Khan, E. A. Loseva

“…Having compared the prognostic significance of common biomarkers, the authors provided general recommendations for a comprehensive preclinical assessment of urinary system function, including laboratory investigations, instrument-based tests, and necropsy. …”
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Rumen microbiome nutriomics: Harnessing omics technologies for enhanced understanding of rumen microbiome functions and ruminant nutrition by Zhongtang Yu, Ming Yan, Jiakun Wang

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Impact of post-COVID-19 syndrome on quality of life and functionality in ethnically diverse and vulnerable populations in the Amazon by Marcelo Silva de Paula, Sheyla Mara Silva de Oliveira, Tatiane Costa Quaresma, Guilherme Augusto Barros Conde, Laura Maria Vidal Nogueira, Valney Mara Gomes Conde, Adjanny Estela Santos de Souza, Waldiney Pires Moraes, Camila Castilho Moraes, Marcos Manoel Honorato, Daliane Ferreira Marinho, Franciane de Paula Fernandes, Lívia de Aguiar Valentim

“…Abstract This study investigated the impact of post-COVID-19 syndrome on the quality of life, mental health, and functional capacity of individuals from ethnically diverse and socioeconomically vulnerable populations in the Brazilian Amazon. …”
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Exploring the Impact of Semaglutide on Cognitive Function and Anxiety-Related Behaviors in a Murine Model of Alzheimer’s Disease by Ianis Kevyn Stefan Boboc, Petrica-Daniel Dumitrelea, Andreea Daniela Meca, Liliana Mititelu-Tartau, Maria Bogdan

“…Conclusions: The findings of this pilot study suggest that SEM may play a dual role in managing AD by improving glycemic control and potentially enhancing cognitive function. As the landscape of AD treatment evolves, the comprehensive approach of utilizing SEM could pave the way for innovative interventions targeting the complex interplay of metabolic and cognitive dysfunctions in this challenging neurodegenerative disorder.…”
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Identification and functional characterization of the RPP13 gene family in potato (Solanum tuberosum L.) for disease resistance by Baoqi Yuan, Chuang Li, Qingfeng Wang, Qi Yao, Xiaowei Guo, Yuhang Zhang, Zhongwei Wang

“…The RPP13 gene family is known to play a pivotal role in plant disease resistance responses; however, its specific functions in potato remain unclear. In this study, we conducted the first comprehensive identification and analysis of 28 RPP13 gene family members in potato, examining their gene structures, chromosomal locations, expression patterns, and functional characteristics. …”
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Plant-Derived Exosomes: Carriers and Cargo of Natural Bioactive Compounds: Emerging Functions and Applications in Human Health by Sorur Yazdanpanah, Silvia Romano, Anna Valentino, Umberto Galderisi, Gianfranco Peluso, Anna Calarco

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CO30 | Joint prosthetic surgery in patients with hemophilia A: clinical-functional outcomes and quality of life

“…It is a major source of morbidity in patients with severe hemophilia A, significantly impairing their functional independence and quality of life. The knee, hip, and ankle are the most frequently affected joints, often requiring surgical intervention when conservative measures are no longer effective. …”
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Effects of isometric muscle training on shoulder pain, function and performance in bowlers: A randomized clinical trail by Sheeraz Ali, Ubaid Ullah, Riafat Mehmood, Osama Faisal, Helping Hand Rehabilitation Center Lower Dir Khyber Pakhtunkhwa Pakistan, Muhammad Khalil ur Rehman

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Pediatric Tuina for the treatment of functional dyspepsia: A systematic review and meta-analysis of randomized controlled trials by Na-Yeon Ha, Chang-Yul Keum, Jinsung Kim

“…Background: Functional dyspepsia (FD) is the most prevalent pediatric gastrointestinal disorder, imposing a significant burden on healthcare services and often persisting into adulthood. …”
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