Histone and non-histone lactylation: molecular mechanisms, biological functions, diseases, and therapeutic targets by Xia Peng, Juan Du

“…Histone lactylation has been observed in H2A, H2B, H3, and H4, with H3K18la and H4K12la being the most extensively studied sites, linked to numerous biological functions. …”
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Comprehensive DFT study of 3-(2-furyl)-1 H-pyrazole-5-carboxylic acid: structural, spectroscopic, and electronic properties with optoelectronic implications by Mücahit Yılmaz

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Effects of Alternative Wrist Grip Techniques on Pain, Strength, and Function in the Wrists of Novice Weightlifters by Muhammad Usama, Saba Riaz, Muhammad Muzammil, Ahmer Ali, Ayesha Noor

“…However, diseases or injuries can significantly impair wrist function, necessitating a comprehensive understanding of its anatomy and biomechanics. …”
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What are end-users' needs and preferences for a comprehensive e-health program for type 2 diabetes? - A qualitative user preference study. by Tina Rishaug, Anne-Marie Aas, André Henriksen, Gunnar Hartvigsen, Kåre Inge Birkeland, Eirik Årsand

“…To ensure end-users' satisfaction with the program and increase motivation for long-term usage, the participants rendered tailoring of desired functionalities and content as crucial.<h4>Conclusion</h4>Based on the findings, a list of recommendations was created, containing the most crucial functionalities and features to include when developing e-health and/or m-health tools for people with pre-diabetes and T2D. …”
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Exploring the Neural Correlates of Visuospatial Memory: A Comprehensive Review of Brain Activity Assessment in Immersive Virtual Reality Research During the Last Decade by Tania Llana, David Perpetuini, Candela Zorzo, Marta Mendez

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A comprehensive analysis to reveal the underlying molecular mechanisms of natural killer cell in thyroid carcinoma based on single-cell RNA sequencing data by Xiaoqiong Li, Kejiang Wang, Jiaxin Liu, Yan Li

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Physical activity modifies associations between cerebrospinal fluid tau measures and executive function by Ryan J. Dougherty, Anja Soldan, Corinne Pettigrew, Barry Greenberg, Adam P. Spira, Abhay Moghekar, Marilyn Albert

“…METHODS One hundred and seventeen adults free of dementia from the BIOCARD study (mean age 72.2 ± 8.0 years, 70% women) wore a wrist accelerometer for 1 week, underwent lumbar puncture to collect CSF, and completed a comprehensive neuropsychological exam. Multivariable linear regression analyses were used to examine whether physical activity (total activity counts over the 10 most active hours of the day) moderates the association between AD CSF biomarkers [Aβ42/40, phosphorylated tau (p‐tau181), and total tau] and cognitive composite scores (episodic memory, executive function). …”
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Genetic and functional characterization of inherited complex chromosomal rearrangements in a family with multisystem anomalies by He Fang, Stephen M. Eacker, Yu Wu, Whitney Neufeld-Kaiser, Mercy Laurino, Siobán Keel, Marshall S. Horwitz, Yajuan J. Liu

“…Purpose: Complex chromosomal rearrangements (CCRs) are rare structural variants involving 3 or more chromosomal breakpoints. Most de novo-reported CCRs pose challenges for diagnosis and management. …”
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Unraveling the cohesin-chromatin interface: identifying protein interactions that modulate chromosome structure and function by Natalie L. Rittenhouse, Riya Gohil, June E. Arricastres, Jill M. Dowen

“…Conclusions This work represents the most comprehensive investigation of cohesin-interacting proteins to date. …”
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Highly conserved ion binding sites are not all functionally relevant in mouse KCC4 by Lisa Becker, Jens Hausmann, Rieke Wellpott, Anna-Maria Hartmann, Anna-Maria Hartmann

“…Three out of five residues (N131, Y216, and T432) are functionally relevant for potassium coordination. For chloride coordination in Cl1, all three residues (G134, V135, and I136) are important, whereas three out of four residues (G433, M435, and Y589) are relevant for chloride binding in Cl2. …”
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STAT1β modulates the tumor immune microenvironment to improve prognosis in ovarian cancer: a comprehensive study of transcriptional and protein expression differences by Ning Lan, Xintong Li, Yifan Qiao, Siyi Zhang, Min Chen, Xiaofeng Yang, Yuliang Zou, Juan Ren, Meili Pei

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Fc-effector functional antibody assays for SARS-CoV-2 variants of concern by Xuemin Chen, Grace Li, Caroline Ciric, Theda Gibson, Larry J. Anderson, Larry J. Anderson, Christina A. Rostad, Christina A. Rostad

“…Combining Fc-mediated functional and neutralizing antibody assays provides a more comprehensive model for understanding vaccine-induced immunity and optimizing vaccination strategies.…”
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STRUCTURAL AND FUNCTIONAL CHANGES EVALUATED BY ECHOCARDIOGRAPHY IN PATIENTS WITH SYSTEMIC SCLEROSIS AND HEART RATE VARIABILITY by E. O. Saad, L. P. Ananyeva, R. T. Alekperov, D. S. Novikova, Yu. O. Korsakova, A. V. Volkov

“…Objective: to estimate heart rate variability (HRV) in patients with systemic sclerosis (SS) and to investigate their relationship to echocardiographic structural and functional changes in the heart.Subjects and methods. …”
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Effects of traditional Chinese exercises on cardiopulmonary function in stroke patients: A meta-analysis by Danmeng Tong, Hongyu Li, Wei Zhao, Wang Guo, Bin Chen, Qiang Tang

“…Conclusions: Traditional Chinese exercise positively influences cardiorespiratory function in stroke patients, demonstrating the most significant improvements in athletic endurance and cardiac function. …”
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Gaps in the physical therapy approach to functioning and disability after stroke: a scoping review by Sofia Queiros Vieira, Shamyr Sulyvan de Castro

“…With the ICF categories, a more detailed content analysis was conducted, enabling a precise comparison across intervention settings. We found that the functioning/disability approach mostly focuses on covering the activity elements of the biopsychosocial model, mainly mobility and self-care, regardless of the intervention setting. …”
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Impacts of microplastics on agroecosystem multifunctionality: From plant production to soil microbial diversity and functions by Zhenxiu Liu, Yali Liu, Zifang Zhou, Yangbeijia Liu, Shiqiang Ge, Chang Shen, Ziqiang Liu, Jianwu Wang

“…Ubiquitous microplastics (MPs) in agricultural practices garner global concerns, with potential implications for agroecosystem functions and services. The comprehensive evaluation of MPs impacts in agroecosystem is imperative and crucial for understanding their ecological risks. …”
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Elucidating the role of compositional and processing variables in tailoring the technological functionalities of plant protein ingredients by Lorenzo Barozzi, Stella Plazzotta, Ada Nucci, Lara Manzocco

“…To fill this gap, abundant literature has appeared but data are hardly comparable due to the absence of a recognized classification of PP ingredients accounting not only for protein purity but also for the process history, and of standardised protocols for technological functionality assessment. In this review, a comprehensive analysis of comparable literature data was thus carried out to elucidate the effect of composition and processing variables on PP technological functionalities. …”
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“New technologies” and “old values”: The function of various text and media forms in literary studies by Anette Svensson

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Identification and Preliminary Functional Analysis of Responsive Genes to Short-term Heat Stress in Lettuce by Shuping He, Guotao Huo, Guojun Ge, Li Du, Du Long, Lijun Luo, Ping Long, Shiwei Wei

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Research progress and prospect of underground utilization of coal-based solid waste functional materials by Jixiong ZHANG, Nan ZHOU, Hengfeng LIU, Yachen XIE, Zhihui SUN, Shenyang OUYANG

“…The paper systematically introduces the classification and properties of coal-based solid waste functional materials, deeply explores the mechanisms and methods for regulating the properties of these materials, and comprehensively looks forward to the development directions of coal-based solid waste functional materials. …”
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