Long-term functional outcomes after aneurysmatic subarachnoid hemorrhage: a review by Karlo Prižmić, Hrvoje Barić, Helena Ljulj, Sara Komljenović, Ivo Somek, Lana Maljković, Vjerislav Peterković, Vjenceslav Vrtarić, Irina Bagić, Goran Mrak

“…Despite improvements in survival, morbidity, associated societal burden and economic cost in survivors remains high. Comprehensive data on long-term cognitive outcomes in aSAH survivors are lacking. …”
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A Novel Hypoxia-Related Gene Signature with Strong Predicting Ability in Non-Small-Cell Lung Cancer Identified by Comprehensive Profiling by Huajun Yang, Zhongan Wang, Ling Gong, Guichuan Huang, Daigang Chen, Xiaoping Li, Fei Du, Jiang Lin, Xueyi Yang

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Optimizing Total Ankle Arthroplasty Analysis: A Comprehensive Assessment of Alignment and Patient-Reported Outcome Measures via Weight-Bearing CT by Carlos Felipe Albarrán MD, MSc, Mario Ignacio Escudero MD, Carlos Felipe Muñoz MD, Eddie Birman MD, Hugo Letelier MD, Felipe Chaparro MD, Giovanni Carcuro MD, Manuel Jose Pellegrini MD

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Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders by Huizhen Liu, Ming Zhang, Minqi Chen, Liusi Chen, Tingrong Huang, Tingrong Huang, Zhao Ye, Zhao Ye

“…Concurrently, exercise has been shown to improve several indicators of heart function.MethodsA comprehensive search was conducted across seven databases. …”
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Characterization and functional analysis of the BAM gene family in peanut (Arachis hypogaea L.) by Chaonan Shi, Peilin Li, Long Li, Long Li, Zhitao Qi, Tong Lu, Jinming Shi, Haodong Yang, Jin Wu, Jingyu Guo, Minghui Liu, Xiaozong Wu

“…This comprehensive analysis provides a holistic view of the potential functions of the AhBAM families in peanuts and lays the foundation for future experimental validation of their roles in enhancing peanut stress resistance and productivity.…”
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Socioeconomic inequalities in patient-reported outcome measures among total hip and knee arthroplasty patients: a comprehensive analysis of instruments and domains by Joshua M. Bonsel, Max Reijman, Erin M. Macri, Jan A. N. Verhaar, Liza N. van Steenbergen, Gouke J. Bonsel

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Deep behavioral phenotyping tracks functional recovery following tibia fracture in mice by Jonathan E. Layne, Dustin M. Snapper, Dustin M. Snapper, Molly E. Czachor, Charles Lam, Jacob D. Matityahu, Dane R. G. Lind, Matthieu Huard, Johnny Huard, Kazuhito Morioka, Julian C. Motzkin, Julian C. Motzkin, Allan I. Basbaum, Jarret A. P. Weinrich, Jarret A. P. Weinrich, Chelsea S. Bahney, Chelsea S. Bahney

“…Our goals were to identify and characterize metrics most indicative of fracture-induced behavioral impairment and to use these metrics to quantify how functional recovery is altered in mice with pin stabilized versus non-stabilized fractures. …”
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Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases by Ana I. Rojo, Brigitta Buttari, Susana Cadenas, Ana Rita Carlos, Antonio Cuadrado, Ana Sofia Falcão, Manuela G. López, Milen I. Georgiev, Anna Grochot-Przeczek, Sentiljana Gumeni, José Jimenez-Villegas, Jarosław Olav Horbanczuk, Ozlen Konu, Isabel Lastres-Becker, Anna-Liisa Levonen, Viktorija Maksimova, Charalambos Michaeloudes, Liliya V. Mihaylova, Michel Edwar Mickael, Irina Milisav, Biljana Miova, Patricia Rada, Marlene Santos, Miguel C. Seabra, Dubravka Svob Strac, Sandra Tenreiro, Ioannis P. Trougakos, Albena T. Dinkova-Kostova

“…Research on model organisms has provided tremendous knowledge of the molecular mechanisms by which NRF2 affects NCDs pathogenesis. This review is a comprehensive summary of the most commonly used model organisms of NCDs in which NRF2 has been genetically or pharmacologically modulated, paving the way for drug development to combat NCDs. …”
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Regulations, biosecurity measures, and impact of COVID-19: A comprehensive mixed method study in traditional wet and live animal markets in Bangladesh by Sukanta Chowdhury, Tushar Kumar Das, Nurun Nahar Chisty, Sajal Kanti Biswas, Mohammed Ziaur Rahman, Jiaxin Ling, Mahmoud M. Naguib, Johanna F. Lindahl

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Indian hidden tuber “Ram Kand Mool” (Maerua oblongifolia A. Rich): Cultivation, phytochemistry and potential applications—A comprehensive review by Poornima Singh, Anurag Singh

“…The leaves and roots of Maerua oblongifolia A. Rich have most commonly been used for ages. This shrub has a mythological importance in Indian beliefs. …”
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Association Between Cognitive Function and Emotion, Sleep, Frailty, and Nutrition in Hospitalized Patients by Nan Wang, Qunying Zhang, Peng Li, Lilan Guo, Xiaoman Wu, Qiuyun Tu

“…Aims In this study we performed a cross‐sectional analysis to comprehensively investigate the relationship between cognitive function and emotion, sleep, frailty, nutrition, and clinical variables in hospitalized geriatric patients according to age group and sex. …”
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Effect of cold plasma processing on the immunoreactivity, structure and functional properties of peanut protein by Yuxin Wang, Jialu Shi, Jing Qian, Jinlong Zhao, Lili Zhang, Vijaya Raghavan, Jin Wang

“…The impact of CP on the immunoreactivity, structure, and functional properties of peanut protein (PP) was investigated, aiming to comprehensively evaluate the influence of CP on PP. …”
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Comprehensive analysis of element and metabolite content between the seeds of Apocynum venetum and Apocynum pictum provides new sights for the salt tolerance in Apocynum by Li Jiang, Yu Zhao, Zijun Jiang, Yukun Wu, Bin Wen, Siyu Zhang, Junyi Zhan, Nana Su

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Comprehensive GWAS and Transcriptome Analysis Discovered Candidate Gene Associated with Starch Pasting Properties of Temperate japonica rice (Oryza sativa L.) by Yoon Kyung Lee, Su Jang, Jihwan Im, Hee-Jong Koh

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Exploring the Anti-Menopausal Potential of Rhizophora mucronata Lam. Ethanol Extract: A Comprehensive Study on Estrogen Receptor β Agonist Activity by Ernawati Ernawati, Moh. Awaludin Adam, Irawati Mei Widiastuti, Era Insivitawati, Muhammad Nikmatullah, Putut Har Riyadi, Mohamad Nor Azra

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Comprehensive Analysis of a circRNA-miRNA-mRNA Network to Reveal Potential Inflammation-Related Targets for Gastric Adenocarcinoma by YunXia Liu, YeFeng Xu, Feng Xiao, JianFeng Zhang, YiQing Wang, YongWei Yao, JieWen Yang

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Incidence of opportunistic infections and its predictors among HIV/AIDS patients on antiretroviral therapy in Gondar University Comprehensive and Specialized Hospital, Ethiopia by Mequanente Dagnaw, Haileab Fekadu, Adhanom Gebre Egziabher, Tesfaye Yesfue, Meera Indracanti, Alemu Tebeje

“…Pneumocystis’ pneumonia at 90(16.51%) was the most encountered OI at follow-up. Adults are presenting with baseline CD4 < 200 cells/µl counts (AHR = 1.41, 95% CI 1.18 to 1.69), bedridden baseline functional status (AHR = 1.35, 95% CI 1.01 to 1.82), WHO clinical stage II (AHR = 5.87, 95% CI 3.97 to 8.69) and WHO clinical stage III (AHR = 5.85, 95% CI 3.55 to 9.65) were notably associated with the incidence of opportunistic infections development. …”
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Comprehensive analysis of scRNA-seq and bulk RNA-seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathy by Siyu He, Chunyu Li, Mingxin Lu, Fang Lin, Sangyu Hu, Junfang Zhang, Luying Peng, Li Li

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The double-edged sword of distress tolerance: Exploring the role of distress overtolerance in nonsuicidal self-injury by Harin Chung, Gyumyoung Kim, Da-In Kim, Ji-Won Hur

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Rethinking the Sustainability of Industrial Buildings in High-Density Urban Areas: Balancing Adaptability and Public Satisfaction by Xiao Ding, Yuchen Shao, Botao Feng

“…The findings reveal the following: (1) “Reuse of old architectural spaces” is the most critical category to prioritize, and, at the indicator level, “adaptability and efficiency of building reuse”, “public participation in the renewal process”, “cooperative operation structures”, and “planning vision” are identified as the four key influencing factors. (2) The functional layout, historical value, and richness of public amenities in the transformed industrial buildings have a significant positive impact on the evaluation results, while the building’s construction time and floor area do not significantly affect public post-evaluation. (3) Younger and more highly educated groups tend to view the transformed exhibition spaces as tourist attractions, particularly expressing satisfaction with the repurposing of the Kinwei Brewery and OCAT B10 New Hall, and consider the adaptive reuse of industrial buildings to promote sustainable urban renewal (SUR). …”
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