Quality by Design and In Silico Approach in SNEDDS Development: A Comprehensive Formulation Framework by Sani Ega Priani, Taufik Muhammad Fakih, Gofarana Wilar, Anis Yohana Chaerunisaa, Iyan Sopyan

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Numerical Tools for Composite Woven Fabric Preforming by Abel Cherouat, Houman Bourouchaki

“…The prediction of the angular distortion of the reinforcement during draping and the changes in fibre orientation are essential for the understanding of the manufacture process and the evaluation of the mechanical properties of the composite structures. This paper presents an optimization-based method for the simulation of the forming processes of woven fabric reinforced composites. …”
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STUDY OF THE INFLUENCE OF THE COMPOSITION OF CULTURAL MEDIUM ON THE BASIS OF A WHITE CABBAGE ON DEVELOPMENT OF LEUCONOSTOC MESENTEROIDES AT THE PRE-FERMENTATION STAGE by V. V. Kondratenko, O. Yu. Lyalina, N. E. Posokina, A. Yu. Kolokolova, V. I. Tereshonok

“…The main task in the research process was to perform a stepby-step mathematical processing of experimental data and analyze them, to obtain functional dependencies adequately approximating the experimental data for the base (BMS) and modified (MMC) model media. Analysis of the experimental data showed that, depending on the type (composition) of the medium, the same species of microorganisms exhibit different dynamics of titer growth. …”
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Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches by Abdul Qadir, Syed Umer Jan, Muhammad Harris Shoaib, Muhammad Sikandar, Rabia Ismail Yousuf, Fatima Ramzan Ali, Fahad Siddiqui, Abdul Jabbar Magsi, Ghulam Mustafa, Muhammad Talha Saleem, Shafi Mohammad, Mohammad Younis, Muhammad Arsalan

“…The optimized patch was further evaluated for skin irritation, in vivo pharmacodynamics, in silico prediction, and simulation using the GastroPlus TCAT® model and stability. …”
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An efficient p-n type based (NiO/CeO2) hybrid composite photocatalyst and its performance for cationic dye degradation: Probable degradation pathways, optimization activities, and... by Manoj Kumar, Atikur Rahman, Vijay Pratap Singh

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The Impact of High Temperatures on the Strength of Recycled Aggregate Concrete by Kamal Ibtisam, Ali Abed Ammar

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Innovation-Oriented HR Strategy Transformation and Business Model Reengineering: Empirical Insights from Ukrainian Agribusiness

“…The research employs factor analysis to assess the need for business process optimization across the following indicator groups: the integral vector of enterprise resource productivity (land, labour, and capital), reflecting resource efficiency; the integrated vector of business process profitability; the integrated financial vector; and the vector of business model effectiveness. …”
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An effect of the recipe composition on minced meat properties by E. V. Tsaregorodtseva

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Optimized Development of High-Porosity Structural and Thermal Insulation Foam Ceramics Based on Local Natural and Technogenic Raw Materials by Aidana Kuanyshbay, Sayat Niyetbay, Indira Tashmukhanbetova, Ruslanzhan Sadyrov, Nurgul Amangeldi, Laura Mustafa, Akmaral Nurakhova, Ilyas Rustemov, Assel Yesbolat

“…This study explores the optimization of foam ceramic materials through experimental research and mathematical modeling. …”
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A multi-modal graph-based framework for Alzheimer’s disease detection by Najmeh Mashhadi, Razvan Marinescu

“…Each directed path in the graph functions as a DL predictor, supporting both forward propagation for transforming data representations, as well as backpropagation for model finetuning, saliency map computation, and input data optimization. …”
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Enhanced drilling waste-water treatment through magnetic nano-composite coagulant application: A central composite design study by Behrad Shadan, Arezou Jafari, Reza Gharibshahi

“…A magnetic nano-composite coagulant has been designed, originally applied in a specific industrial waste-water treatment, and statistically investigated using Central Composite Design (CCD). …”
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First-principles study on the interfacial interactions between h-BN and Si3N4 by Zhang Kuo, Gao Tengchao, Che Xiangming, Li Yanhua, Li Qun

“…This work provides valuable insights into the interfacial interaction between h-BN and Si3N4 and will give a promising theoretical guidance for designing and optimizing h-BN-based ceramic composites.…”
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Peripheral blood metabolic composite score based on peripheral blood metabolism can be used as an assessment of recurrence after surgery in patients with locally advanced gastric c... by Ning Meng, Zhiqiang Wang, Yaqi Peng, Xiaoyan Wang, Wenju Yue, Le Wang, Jingxia Lv, Jingxia Lv, Jingxia Lv, Wenqian Ma, Wenqian Ma, Wenqian Ma

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A Neural Network Constitutive Model and Automatic Stiffness Evaluation for Multiscale Finite Elements by Aliki D. Mouratidou, Georgios E. Stavroulakis

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Machine learning-driven prognostic prediction model for composite small cell lung cancer: identifying risk factors with network tools and validation using SEER data and external co... by Fei Li, Mengfan Zhao, Linlin Cao, Shuai Qie

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Optimizing blood-brain barrier permeability in KRAS inhibitors: A structure-constrained molecular generation approach by Xia Sheng, Yike Gui, Jie Yu, Yitian Wang, Zhenghao Li, Xiaoya Zhang, Yuxin Xing, Yuqing Wang, Zhaojun Li, Mingyue Zheng, Liquan Yang, Xutong Li

“…Our approach utilizes a variational autoencoder (VAE) generative model integrated with reinforcement learning for multi-objective optimization. …”
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Mathematical Modelling and Optimisation of Operating Parameters for Enhanced Energy Generation in Gas Turbine Power Plant with Intercooler by Anthony O. Onokwai, Udochukwu B. Akuru, Dawood A. Desai

“…This study developed an optimal model for gas turbine power plants (GTPPs) with intercoolers, focusing on the challenges related to power output, thermal efficiency and specific fuel consumption. …”
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Development of a Heat Transfer Model for a Free Double Piston and Identification of Thermal Management Challenges by Konstantinos Fotis, Zinon Vlahostergios, Dimitrios Misirlis, Kyros Yakinthos

“…For this reason, in the present work, a heat transfer model to address the thermal management challenges in this innovative engine design is developed. …”
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Optimization of chlorpheniramine maleate (CPM) delivery by response surface methodology – four component modeling using various response times and concentrations of chitosan-alanin...

“…The release behavior of drug was affected by preparation variables. A central composite design was used to evaluate and optimize the effect of preparation variables; chitosan concentration (X1), percentage of crosslinker (X2), concentration of drug (X3) and release time (X4) on the cumulative amount of drug release, Y in solutions of pH = 2.0 and pH = 7.4, respectively. …”
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A Statistical Modeling and Optimization for Cr(VI) Adsorption from Aqueous Media via Teff Straw-Based Activated Carbon: Isotherm, Kinetics, and Thermodynamic Studies by Surafel Mustefa Beyan, Sundramurthy Venkatesa Prabhu, Temesgen Abeto Ambio, C. Gomadurai

“…The prepared TSAC was characterized using BET, FTIR, SEM, and XRD. A central composite approach-based RSM analysis was undertaken for statistical modeling and optimization for maximized Cr(VI) removal with respect to four important factors, namely, initial concentration of Cr(VI), the dosage of TSAC, pH, and adsorption time. …”
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