Advanced biomaterial strategies for overcoming age-associated wound healing impairments by Rodrigo Dores, Telma A. Rodrigues, Daniel Carvalho, Eva Batista, Myroslava Kozak, Cristina Blanco-Elices, Hugo Fernandes, Luis M. Bimbo

“…Recent advances in aged skin models have established them as crucial platforms for translational research, enabling more accurate prediction of biomaterial performance in elderly patients. …”
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AntagomiR-192-5p-engineered exosomes encapsulated in MXene-modified GelMA hydrogel facilitated epithelization of burn wounds by targeting OLFM4 by Wenzhang Liu, Hongchao Huang, Futing Shu, Yingying Liu, Jiezhi Lin, Lu Yang, Wei Zhang, Luofeng Jiang, Tianyi Liu, Chaoran Xie, Lei Li, Yin He, Shichu Xiao, Yongjun Zheng, Zhaofan Xia

“…Inhibition of miR-192-5p enhanced epidermal cell function by upregulating olfactomedin-4 (OLFM4), a key gene associated with cell proliferation, adhesion and migration. To optimize delivery and therapeutic efficacy, we engineered MSC-derived exosomes loaded with antagomiR-192-5p (ant-192; Final content: 2 nmol per wound; Loading efficiency: 35.22 ± 0.34 %) and then encapsulated into a composite hydrogel composed of GelMA and MXene (Ti3C2Tx) nanosheets, forming a multifunctional dressing (Exo-ant-192@M-Gel). …”
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The association of systemic immune-inflammation index with incident breast cancer and all-cause mortality: evidence from a large population-based study by Yu Li, Yu Li, Meng Yu, Ming Yang, Jingqi Yang

“…Within the breast cancer population, SII exhibited a J-shaped relationship with all-cause mortality. The optimal inflection point for SII/100 in this context was 5.22, and above this threshold, there was a marked escalation in all-cause mortality (HR=1.09, 95% CI: 1.04-1.14).ConclusionThe SII, as a novel inflammatory composite index, is significantly associated with the risk of breast cancer incidence and all-cause mortality in breast cancer patients. …”
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Modification of the WaldBoost algorithm to improve the efficiency of solving pattern recognition problems in real-time by A. N. Chesalin, S. Ya. Grodzenskiy, M. Yu. Nilov, A. N. Agafonov

“…The paper studies modifications of compositions (ensembles) of algorithms for solving real-time pattern recognition problems. …”
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Dynamic Aerial Small Target Detection Algorithm Based on Compound Zoom Scaling by Jiang Yuan, Zhu Gaofeng, Zhu Fenghua, Xiong Gang

“…Firstly, a more efficient backbone network is introduced, and a composite scaling method is employed to optimize the balance among network depth, width, and image resolution. …”
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Neutron Cross-Section Uncertainty and Reactivity Analysis in MOX and Metal Fuels for Sodium-Cooled Fast Reactor by Oyeon Kum

“…These results underscore the importance of accurate nuclear data libraries to minimize uncertainties in criticality evaluations, and they provide a foundation for optimizing fuel compositions and refining reactor control strategies. …”
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Psycholinguistic Peculiarities of the Development of Communicative Competence of Teachers of Secondary Schools by Едуард Івашкевич, Людмила Примачок

“…In the content of communicative competence of teachers we can emphasize the ability to optimize interpersonal relationships in the group; social sensitivity; a set of communicative skills, behavior patterns and communication techniques; a communicative potential; the interpretative competence. …”
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A multifunctional hydrogel system with synergistic effects against Staphylococcus aureus infections and inflammation in perioperative cataract surgery by Wendi Zheng, Meiting Lin, Hong Cheng, Xiang Gao, Yongguo Xiang, Wenjuan Wan, Shijie Zheng, Xiaobei Huang, Ke Hu

“…Given its noninvasive nature, simple yet composite regimen, and feasibility for clinical translation, FQT1/8 presents a promising approach for perioperative cataract management.…”
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Combined healthy lifestyles and overactive bladder: a cross-sectional study of NHANES 2007–2020 by Tianjie Li, Tianjie Li, Jian Hou, Bo Xiao, Jianxing Li, Xiaodong Liu

“…Weighted multivariable logistic regression models were employed to assess the association between the healthy lifestyle score and risk of OAB, adjusting for demographic, socioeconomic, and clinical covariates.ResultsAmong the 20,195 participants, 3,901 (14.58%) were identified as having OAB. …”
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Caninoid Necro-Robots: Geometrically Selected Rearticulation of Canine Mandibles by Ben Jørgensen, Oscar Powell, Freddie Coen, Jack Lord, Yang Han Ng, Jeremiah Brennan, Gurå Therese Bergkvist, Parvez Alam

“…Our research uses 3D scans of a real canine head, which is modelled using the finite element method to ascertain optimal geometrical reinforcements for the mandible. …”
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Ticagrelor versus Clopidogrel in Patients with Severe Renal Insufficiency Undergoing PCI for Acute Coronary Syndrome by Yunxian Chen, Shaowen Tu, Zhixin Chen, Jue Xia, Baofeng Chen, Jinfeng Chen, Jiarong Liang, Xiangyang Liu, Liangqiu Tang

“…We used the adjusted Cox proportional hazards models to analyze the 1-year outcome endpoints, including the primary endpoint (the composite of cardiovascular death, recurrence of MI, or nonfatal ischemic stroke), death from any cause, and bleeding events (Bleeding Academic Research Consortium, BARC criteria). …”
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Recent Advances in Nanozymes for the Treatment of Atherosclerosis by Zou Z, Bi X, Ma H, Chen L, Jin H, Gong S, Li X, Liu X

“…This review comprehensively summarizes recent advances in nanozyme-based interventions for AS, focusing on representative systems such as Prussian blue, cerium oxide, selenium-based, and multifunctional composite nanozymes. We critically discuss their design principles, catalytic mechanisms, lesion-targeting strategies, and therapeutic outcomes in preclinical models. …”
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Computerized cognitive testing to capture cognitive decline in Alzheimer's disease: Longitudinal findings from the ARMADA study by Roos J. Jutten, Emily H. Ho, Tatiana Karpouzian‐Rogers, Carol van Hulle, Cynthia Carlsson, Hiroko H. Dodge, Cindy J. Nowinski, Richard Gershon, Sandra Weintraub, Dorene M. Rentz

“…DISCUSSION These findings support the use of the NIHTB‐CB in early AD, but also imply that the optimal NIHTB‐CB composite score to detect change over time may differ across clinical stages of AD. …”
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Association of urbanization-related factors with tuberculosis incidence among 1992 counties in China from 2005 to 2019: a nationwide observational study by Yaping Wang, Xiaoqiu Liu, Yuhong Li, Min Liu, Yiheng Wang, Hongliang Zhang, Jue Liu, Yanlin Zhao

“…The annual incidence rate and number of TB cases were obtained from the national Tuberculosis Information Management System, maintained by the Chinese Center for Disease Control and Prevention. Fixed-effects models were used to examine the association between urbanization factors and TB incidence. …”
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Latent classes of anthropometric growth in early childhood using uni- and multivariate approaches in a South African birth cohort. by Noëlle van Biljon, Marilyn T Lake, Liz Goddard, Maresa Botha, Heather J Zar, Francesca Little

“…<h4>Conclusions</h4>With the identification of these classes, a better understanding of distinct childhood growth trajectories and their predictors may be gained, informing interventions to promote optimal childhood growth.…”
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A reliable analytical procedure to determine the carbon isotopic signature of CO₂-bearing COH fluids generated in petrological experiments by L. Toffolo, L. Minopoli, E. Ferrari, S. Tumiati

“…This offers a multitude of opportunities in designing experiments focused on determining isotopic fractionation models for geological processes that involve, but are not restricted to, CO<span class="inline-formula">₂</span>-bearing COH fluids.…”
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Mechanisms of Chromium Removal from Water and Soil Using Bioleached Nano Zero-Valent Iron-Mediated Biochar via Co-Pyrolysis by Zhiyi Liu, Shuhong Zhou, Yubing Cai, Xuehai Zhang, Muhammad Shaaban, Qi-an Peng, Yajun Cai

“…In aqueous conditions, the removal capacity of Cr(VI) by nZVI@BC increased by 72.01% and 66.92% compared to biochar (BC) and biochar–bioleachate composite (BBC), respectively. Under optimal conditions, nZVI@BC eliminated 90.11% of 20 mg/L Cr(VI), with experimental data fitting the Freundlich and pseudo-second-order kinetic models. …”
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Efficient removal of tetracycline from wastewater using chitosan-based aerogels functionalized with natural zeolite, Fe₃O₄, and MOF-808 by Fatemeh Babaei, Rauf Foroutan, Abolfazl Tutunchi, Mehrshad Ahmadi, Bahman Ramavandi

“…In this study, chitosan (CS) aerogel, a CS/N-zeolite composite, and a magnetic nanocomposite (CS/N-zeolite/Fe₃O₄/MOF-808) were developed as efficient, eco-friendly adsorbents for tetracycline (TC) removal from pharmaceutical wastewater. …”
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Remnant cholesterol inflammatory index, calculated from residual cholesterol to C-reactive protein ratio, and stroke outcomes: a retrospective study using the National institutes o... by Yanmei Yu, Yiming Zhang, Chunyan Zhu, Tingting Duan, Zichen Rao

“…Subpopulation analysis, inflection point analysis, generalized additive models (GAM), and receiver operating curve (ROC) analyses were utilized to evaluate the ability of these biomarkers to predict outcomes and to identify their optimal cutoff points. …”
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Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms by Jozsef Nagy, Wolfgang Fenz, Stefan Thumfart, Julia Maier, Zoltan Major, Harald Stefanits, Maria Gollwitzer, Johannes Oberndorfer, Nico Stroh, Michael Giretzlehner, Michael Sonnberger, Andreas Gruber, Philip-Rudolf Rauch, Matthias Gmeiner

“…Abstract Accurate rupture risk assessment is essential for optimizing treatment decisions in patients with cerebral aneurysms. …”
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