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2261
Kinetics and thermodynamics of Mn(II) removal from aqueous solutions onto Mg-Zn-Al LDH/montmorillonite nanocomposite
Published 2018-12-01“…The data indicated that Langmuir model fits the experimental data better than Freundlich model and pseudo-second order model is sufficient to depict the kinetics of Mn(II) onto Mg-Zn-Al (LDH)/MMT composite. …”
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2262
Targeting the activated microenvironment with endosialin (CD248)-directed CAR-T cells ablates perivascular cells to impair tumor growth and metastasis
Published 2024-02-01“…We hypothesized that targeting the endosialin (CD248) receptor, strongly expressed by tumor-associated pericytes and perivascular cancer-associated fibroblasts, would circumvent these challenges and offer an exciting antigen for CAR-T cell therapy due to the close proximity of target cells to the tumor vasculature, the limited endosialin expression in normal tissues and the lack of phenotype observed in endosialin knockout mice.Methods We generated endosialin-directed E3K CAR-T cells from three immunocompetent mouse strains, BALB/c, FVB/N and C57BL/6. E3K CAR-T cell composition (CD4+/CD8+ ratio), activity in vitro against endosialin+ and endosialin– cells, and expansion and activity in vivo in syngeneic tumor models as well as in tumor-naive healthy and wounded mice and tumor-bearing endosialin knockout mice was assessed.Results E3K CAR-T cells were active in vitro against both mouse and human endosialin+, but not endosialin–, cells. …”
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2263
Wettability alteration and IFT reduction during carbonated water injection; a critical investigation into the role of pH
Published 2024-10-01“…Gaining insight into these processes is essential for optimizing EOR strategies, improving predictive models, and enhancing CO2 sequestration. …”
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2264
Capturing the Heterogeneity of the PDAC Tumor Microenvironment: Novel Triple Co-Culture Spheroids for Drug Screening and Angiogenic Evaluation
Published 2025-03-01“…These models were assessed through growth assays, multicolor flow cytometry to optimize cell ratios, cell viability assays to evaluate drug responses, and a tube formation assay with a spheroid-conditioned medium to examine angiogenesis. …”
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2265
Study of the effect of cutting modes on output parameters under high-speed steel turn-milling
Published 2022-07-01“…An experimental research method was applied to verify the adequacy of the mathematical model. The experiment was planned according to the non-composite design proposed by Box and Behnken. …”
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2266
Congo red adsorption in water using a novel nano zero-valent iron intercalated Zn–Al–CO3 layered double hydroxide: adsorption isotherm, kinetics and thermodynamics
Published 2025-06-01“…Kinetic and isotherm studies revealed that pseudo-second-order (PSO) kinetic and Redlich-Peterson models had the best fit compared to other kinetic and isotherm models used. …”
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2267
Development of Adaptive Testing Method Based on Neurotechnologies
Published 2022-04-01“…The aim of the study is to create neural network models of modules in an adaptive testing system to design an individual testing trajectory.The research article discusses the implementation of an adaptive testing system in terms of introducing artificial neural network modules into its composition, which should solve the problem of choosing a topic and the complexity of the next question, taking into account previous answers and the complexity of previously asked questions, as well as the connectivity of topics and response time as a factor guessing or searching for an answer, thereby forming an individual testing trajectory.Materials and methods. …”
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2268
Comprehensive experimental study of multivariable oil–brine–rock interactions: impact of brine–rock chemistry and crude oil polarity on enhanced oil recovery in carbonate reservoir...
Published 2025-07-01“…These results highlight the relevance of surface charge in EOR processes and support the development of charge-based recovery models.…”
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2269
Spray drying of buriti oil-in-water emulsions as potential systems for the delivery of bioactive compounds
Published 2025-12-01“…Based on the adjusted quadratic models of response variables, the optimal conditions were determined: SPI 5.45 % w/w and drying temperature of 180 °C, with a low predictive error and a desirability of 0.884. …”
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2270
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients
Published 2025-07-01“…Methods In this study, stool samples from 67 patients were collected preoperatively and 1 month postoperatively and metagenomic sequencing was performed to assess the composition of the gut microbiota. The differential abundances of species and MetaCyc pathways were analyzed using microbiome multivariate associations with linear models. …”
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2271
Prediction of Gait Neurodegenerative Diseases by Variational Mode Decomposition Using Machine Learning Algorithms
Published 2024-12-01“…Prediction of different neurodegenerative disease such as Parkinsons Disease (PD), Huntingtons Disease (HD), Amyotrophic Lateral Sclerosis (ALS) and healthy subjects are carried out by Multilayer Perceptron (MLP) with the parameters optimized with Genetic Algorithm (GA). The results of the experiments shows that the proposed model produces a better accuracy of 98.4% than the other existing algorithms for the gait dataset.…”
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2272
Regional analysis of myelin basic protein across postnatal brain development of C57BL/6J mice
Published 2025-03-01“…This study aims to address this gap by providing a detailed spatiotemporal account of MBP distribution across 13 developmental ages from postnatal day 2 to 60. We used an optimized immunohistochemistry protocol to overcome the challenges of myelin’s unique lipid-rich composition, enabling more consistent staining across diverse brain structures and developmental stages, offering a robust baseline for typical myelination patterns, and enabling comparisons with pathological models. …”
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2273
Characteristics and risk profile of the over fifty adult congenital heart surgical population, a retrospective cohort
Published 2025-06-01“…Primary outcome was the composite of severe postoperative complications and secondary outcomes were 1-year mortality, ICU stay and hospital length of stay. …”
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2274
A methodology for evaluating the fracture width of a notched RC multiple-layer flat slab under cyclic loading
Published 2025-06-01“…This model not only bridges the gap between theory and practical application in crack width prediction but also contributes to optimizing durability in RC structures exposed to cyclic stresses. …”
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2275
Experimental study on cobalt adsorption by bone powder modified with poly Pyrrole and polyethylene glycol
Published 2025-03-01“…Increasing the initial pH of the solution enhanced the adsorption capacity, with maximum cobalt adsorption observed at pH 7. The optimal composite adsorbent demonstrated an equilibrium time of 30 mins. …”
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2276
Analysis of the Blasting Compaction on Gravel Soil
Published 2015-01-01“…Then, the thermal strains got from the model are used to estimate the displacement of surrounding soil to predict the degree of compaction and optimize the distribution of blast holes in plan.…”
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2277
How spatial resolution mediates canopy spectral diversity as a proxy for marsh plant diversity
Published 2025-12-01“…Spectral reflectance variations comprehensively capture differences in the biochemical composition and morphological characteristics among plant species, making them a promising approach for monitoring and estimating plant diversity. …”
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2278
DMSO-free cryopreservation of hiPSC-derived cardiomyocytes: low temperature characterization and protocol development
Published 2025-06-01“…A differential evolution (DE) algorithm was utilized to determine the optimal composition of a mixture of a sugar, sugar alcohol and amino acid to replace DMSO as the CPA. …”
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2279
Transinger: Cross-Lingual Singing Voice Synthesis via IPA-Based Phonetic Alignment
Published 2025-06-01“…Transinger achieves breakthroughs in phoneme representation learning by precisely modeling pronunciation, which effectively enables compositional generalization to unseen languages. …”
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2280
Beyond the Surface: Mesophotic Reefs as Potential Refuges for Shallow Fish Assemblages
Published 2024-12-01“…Generalized linear models revealed significant variations in reef fish composition across spatial (site and zone) and temporal (season and year) dimensions. …”
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