Machine learning-derived diagnostic model of epithelial ovarian cancer based on gut microbiome signatures by Cheng Chen, Chengyuan Deng, Yanwen Li, Shuguang He, Yunhong Liu, Shuwen Pan, Wenqian Xu, Lu Fang, Yixi Zhu, Yingying Wang, Xiaoxin Jiang

“…The clinical data and pathological characteristics were comprehensively recorded for further analysis, PICRUSt2 was utilized to conduct an analysis of microbial functional predictions, WGCNA networks were constructed by integrating microbiome and clinical data. …”
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Forest fire hazard assessment based on forest typology by Volodymyr P. Voron, Andriy D. Kuzyk, Sergiy V. Ivashyniuta, Yilia R. Tsipan

“…The greatest representation of fire-prone species was observed in dry pine forests (A1), where out of 11 species, 8 have a high inflammability. …”
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Single-cell sequencing on PBMCs from patients with HA and HB with inhibitors reveals different immune responses to FVIII and FIX by Enhao Li, Zekun Li, Jinzeng Wang, Haoyang Wu, Yilun Xue, Can Lou, Zhenping Chen, Feng Liu, Wenman Wu, Qiulan Ding, Runhui Wu, Xuefeng Wang, Jing Dai

“…Transcriptome analysis revealed differences in the composition of lymphocyte subsets and the functional status of immune cells between the HA and HB groups. …”
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Effects of tongue tamers and customized bonded spurs as an early treatment of anterior open bite: a randomized clinical study by Safa B. Alawy, Shaimaa S. EL-Desouky, Ibrahim A. Kabbash, Shimaa M. Hadwa

“…Overjet decreased in all groups, with the greatest reduction observed in group-I(-2.58 ± 1.02 and -2.47 ± 0.80 in model and cephalometric respectively) and was significantly different from group-II using pairwise analysis. …”
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Treatment of extensive tumors of the jaws by hemimandibuloectomy with simultaniouse reconstruction of the mandible, arthroplasty of temporomandibular joint, orthopedic rehabilitati... by C. R. Rahimov, A. A. Ahundov, G. I. Hajiyeva, R. Ch. Rahimli, D. A. Safarov, I. M. Farzaliyev

“…Within virtual preoperative planning one performed: resection of the mandible associated with exarticulation of condylar head, virtual plate bending according to contours of the mandible (that were determined by application of “mirror” function of virtual planning software), arthroplasty of temporomandibular joint, determination of donor site on fibula bone, osteotomy of fibula free flap, positioning of dental implants, transferring of composite flap and it’s fixation by reconstructive plate. …”
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Genetic and transcriptional insights into immune checkpoint blockade response and survival: lessons from melanoma and beyond by Jiaxin Wen, Yanfeng Wang, Song Wang, Yuxin Liang, Xiaozhen Hu, Qiuxiang Ou, Hua Bao, Kuo Zhao, Youyu Wang

“…DNAH-altered melanomas exhibited upregulation of chemokine signaling, cytokine-cytokine receptor interaction, and cell cycle-related pathways, along with elevated expression of immune-related signatures in interferon signaling, cytolytic activity, T cell function, and immune checkpoints. Using LASSO logistic regression, we identified a 26-gene composite signature predictive of clinical response, achieving an area under the curve (AUC) of 0.880 (95% CI 0.825–0.936) in the training dataset and 0.725 (95% CI 0.595–0.856) in the testing dataset. …”
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Conserving biodiversity, carbon, and community values in a fragmented landscape by A. Susilowati, Y. Lisnawati, H.H. Rachmat, H. Kurniawan, W.C. Adinugroho, R. Imanuddin, D.J. Sudrajat, I.W.S. Dharmawan, M. Iqbal, S. Fahmi, L.M. Nugraha, E. Novriyanti, E. Sutrisno, A.B. Siswanto

“…Observations were conducted on 18 sample plots. Vegetation analysis was conducted to assess stand structure and composition, which formed the basis for calculating carbon stock potential. …”
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Severity of native pulmonary annular hypoplasia and late outcomes of tetralogy of Fallot: retrospective cohort study by Tugba Erdil, Klaus Steigmiller, John Ethan Rampa, Martin Christmann, Ulrike Held, Hitendu Dave

“…The Kaplan-Meier 10-year freedom from primary outcome was 85% (95% CI 78–92%); 69% (46–100%), 91% (82–100%) and 84% (74–95%) for groups 1, 2 and 3, respectively (log rank p = 0.16). Composite dysfunction at follow-up was observed in 29.8% (overall): 45%, 28.6% and 25.9% for groups 1, 2 and 3, respectively (p = 0.12). …”
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A retrospective cohort study of the efficacy and safety of oral azvudine versus nirmatrelvir/ritonavir in elderly hospitalized COVID-19 patients aged over 60 years by Bo Yu, Haiyu Wang, Guangming Li, Junyi Sun, Hong Luo, Mengzhao Yang, Yanyang Zhang, Ruihan Liu, Ming Cheng, Shixi Zhang, Guotao Li, Ling Wang, Guowu Qian, Donghua Zhang, Silin Li, Quancheng Kan, Jiandong Jiang, Zhigang Ren

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Magnetically sensitive nanocomposites for targeted antitumor therapy with application of gemcitabine by N. M. Korniichuk, S. P. Turanska, A. L. Petranovska, M. V. Abramov, P. P. Gorbyk, N. Yu. Luk'yanova, N. V. Kusyak, V. F. Chekhun

“…The thickness of the adsorbed layer of GEM in the composition of Fe3O4@GEM NC was determined by magnetic granulometry. …”
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Traditional Mongolian Medicine Qiqirigan-8 alleviates non-alcoholic fatty liver disease via restoring gut microbiota and metabolism by Dandan Yang, Dandan Yang, Wuyunsiqin, Wuyunsiqin, YanNiu, Hashentuya, Tana, Anna, Mingxing Ma, Wenhui Zhao, Menggenduxi, Minjie Wang, Minjie Wang

“…Hematoxylin and Eosin (H&E)-staining, combined with serum biochemical indexes, was used to observe liver appearance and characterize the pathological changes and functions of the liver. …”
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New tectonic discrimination diagrams for basic and ultrabasic volcanic rocks through log-transformed ratios of high field strength elements and implications for petrogenetic proces... by Surendra P. Verma, Salil Agrawal

“…In addition to other requirements, both these aspects were considered for proposing five new discriminant function diagrams based on log-ratios of five high-field strength elements – (TiO2)adj, Nb, V, Y, and Zr. …”
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Preliminary evaluation of a mindfulness intervention program in women with long COVID dysautonomia symptoms by Elizabeth Vandenbogaart, Matthew Figueroa, Diana Winston, Steve Cole, Julienne Bower, Jeffrey J. Hsu

“…No significant changes were observed for the active stand test or 6MWT. A significant reduction in insomnia severity (ISI: 16.6 vs. 13.6; p = 0.001) was observed post-intervention, but scores reverted toward baseline levels at 4-week follow-up. …”
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Vision-related Quality of Life (VRQOL) and its determinants among the Elderly in rural blocks of Haryana, India by Mona Duggal, Ankita Kankaria, Latika Rohilla, Harashish Jindal, Limalemla Jamir, Parul Chawla Gupta, Debarati Sarkar, Vaibhav Miglani, Akash Kumar, Drishti Sharma, Neha Dahiya, Siddhartha Sharma, Sandeep Grover

“…The study found higher VR-QOL scores in General Health, Distance activities, and Near activities, while lower scores were observed in Mental health, Dependency, Social functioning, Ocular pain, General vision, and Role difficulties. …”
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Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation by Yitao Dai, Vitor Lourenzon, Laura P. Ióca, Dua Al-Smadi, Lydia Arnold, Ian McIntire, Roberto G. S. Berlinck, Alessandra S. Eustáquio

“…Here, we first assign functions to pseudovibriamide biosynthetic genes using reverse genetics. …”
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A study on toxicity, local irritative effect of and allergic response to a novel intranasal medication containing N-phenylacetyl-L-prolylglycine ethyl ester by B. S. Burlaka, I. F. Bielenichev

“…These conditions lead to impairment of mnestic and intellectual brain functions, to a decrease in mental alertness and memory in particular, which results in deterioration in the quality of life, sometimes in disability and patients’ partial or complete dependence on other people. …”
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Effects of pH on Oat Protein Isolate and Pickering Emulsion Stabilized by the Protein by Jing WANG, Yingxue JIAO, Wei GAO, Lipeng FAN, Sunshuo LIANG, Huiting WANG, Lijuan LU, Wenhui QI, Zhisheng ZHANG

“…The structural and functional characteristics of oat protein isolate (OPI) were systematically investigated across varying pH conditions (3, 5, 7, 9, and 11), with emphasis on microstructural properties, Zeta potential dynamics, and protein subunit compositions. …”
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Gut dysbiosis is associated with difficult-to-treat rheumatoid arthritis by Patricia Ruiz-Limón, Patricia Ruiz-Limón, Patricia Ruiz-Limón, Natalia Mena-Vázquez, Natalia Mena-Vázquez, Isabel Moreno-Indias, Isabel Moreno-Indias, Isabel Moreno-Indias, Jose Manuel Lisbona-Montañez, Jose Manuel Lisbona-Montañez, Jose Manuel Lisbona-Montañez, Arkaitz Mucientes, Arkaitz Mucientes, Sara Manrique-Arija, Sara Manrique-Arija, Sara Manrique-Arija, Rocío Redondo-Rodriguez, Rocío Redondo-Rodriguez, Laura Cano-García, Laura Cano-García, Francisco J. Tinahones, Francisco J. Tinahones, Francisco J. Tinahones, Francisco J. Tinahones, Antonio Fernández-Nebro, Antonio Fernández-Nebro, Antonio Fernández-Nebro

“…The gut microbiota was analyzed using 16S rRNA gene sequencing; bioinformatics analysis was performed using QIIME2, and its functionality was inferred through PICRUSt. We recorded data on clinical findings, inflammation, and cytokines. …”
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A vascular endothelial cell, neuron, and microglia tri-culture model to study hypertension-related depression by Hongxia Zhao, Hongxia Zhao, Lingge Huang, Jian Liu, Min Feng, Yeqian Liu, Hong Li, Shan Gong, Chunming Chen, Shuiqing Zeng, Weiqiong Ren

“…Vascular endothelial function and inflammatory levels were assessed using fluorescent probes and enzyme-linked immunosorbent assays. …”
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Clopidogrel Versus Aspirin as Chronic Maintenance Antiplatelet Monotherapy in Patients After Percutaneous Coronary Intervention With Chronic Kidney Disease: A Post Hoc Analysis of... by Jeehoon Kang, Sang‐Hyeon Park, Kyung Woo Park, Bon‐Kwon Koo, Huijin Lee, Minju Han, Doyeon Hwang, Han‐Mo Yang, In‐Ho Chae, Won‐Yong Shin, Ju Hyeon Oh, Yong Hoon Kim, Tae‐Ho Park, Bum Soo Kim, Jung‐Kyu Han, Eun‐Seok Shin, Hyo‐Soo Kim

“…However, it is uncertain whether the beneficial effect of clopidogrel over aspirin is different according to the renal function. Methods and Results We conducted a post hoc analysis of the HOST‐EXAM trial. …”
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